Bos indicus (zebu cattle): 109578279 Help Entry 109578279         CDS       T04792                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism biu  Bos indicus (zebu cattle) Pathway biu04072   Phospholipase D signaling pathway biu04115   p53 signaling pathway biu04140   Autophagy - animal biu04150   mTOR signaling pathway biu04151   PI3K-Akt signaling pathway biu04152   AMPK signaling pathway biu04211   Longevity regulating pathway biu04218   Cellular senescence biu04714   Thermogenesis biu04910   Insulin signaling pathway biu04919   Thyroid hormone signaling pathway biu05163   Human cytomegalovirus infection biu05165   Human papillomavirus infection biu05168   Herpes simplex virus 1 infection biu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     109578279 (TSC2)    04151 PI3K-Akt signaling pathway     109578279 (TSC2)    04152 AMPK signaling pathway     109578279 (TSC2)    04150 mTOR signaling pathway     109578279 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     109578279 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     109578279 (TSC2)    04218 Cellular senescence     109578279 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109578279 (TSC2)    04919 Thyroid hormone signaling pathway     109578279 (TSC2)   09149 Aging    04211 Longevity regulating pathway     109578279 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     109578279 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109578279 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     109578279 (TSC2)    05163 Human cytomegalovirus infection     109578279 (TSC2)    05165 Human papillomavirus infection     109578279 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:biu01009]     109578279 (TSC2) Protein phosphatases and associated proteins [BR:biu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      109578279 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Motif Other DBs NCBI-GeneID:  109578279 NCBI-ProteinID:  XP_019842880 UniProt:  A0A6P5E0P1 LinkDB All DBs Position 25:2106072..2136960 Genome browser AA seq 1813 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVARTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMVCLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYHMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLNIIERLLQQLQSLDSPELSAIVHDLLSTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDCLETERSSEKKAG CPLSPPAGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDVILKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKELKESSAADAFRCRSISVSEHVVRRIQTSLTSASLGSADENSMAQADDNLKNLHLE LTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLL GLDSGELQGGPELSSDPSMHVRQTKEAPAKLESQAGQQVYHGARDRVRSMSGGHGLRVGA LDAPACYFPSSPTSPGSQTAPASQPEKASAGSPLPAQKEKTNLAAYMPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS AKPSPPPRSNTVASFSSLCQSRCQGKLHRSISWADSAVVLEEGGPGEAGLSAEPPELEDF EATLGSDGRCGRSDAFSRSSSTSSQEEKSFHAEELPPGGIPIERAVSEGSRASVDLAFQP SQPLSKSSSSPELQTLQDILGDPGDKAEVGRLSPEAKARSQSGILDGEGAAWSAPGEERR GRGPAQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKNRAGTSNTEKVPG INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSN SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPL DYECNLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY PSKWIARLRHIKRLRQRIREEAHYSSASLPLMQTHPPGHAKAPAQAPAESTPTYETGQRK RLVSSVDDFTEFV NT seq 5442 nt NT seq  +upstreamnt  +downstreamnt atggctaagccagcaagcaaagattcaggcttgaaggagaagttcaagattcttttggga ctggggactccacggccaaatcccaggtctgcagagggcaaacagactgagtttatcatc accgcggaaatcctgagagagctgagtgttgaatgtggcctcaataatcgcatccgggtg atagggcagatctgtgaggttgccagaacgaagaaattcgaagagcacgcggtggaagca ctctggaaggccgtctcggacctgctgcagccagagcggccacccgaggcccggcatgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcctgggcgttctcagg gccctcttcttcaaggtcatcaaggattacccctctaatgaagacctccacgagagactg gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaagaagagctg gcggactttgtcctgcagtggatggacgttggcctgtcctccgaattcctcctggtgctc gtgaacttagtcaaattcaacagctgttaccttgatgagtacatcgcatccatggtccac atggtctgcctgctgtgtgtccagaccgtgtcctccgtggacatagaggtgtctctgcag gtgctggatgctgtggtctgctacaactgtctgccagccgagagcctccccctattcatc gtcactctctgccgcaccatcaacgtcaaggagctctgtgaaccttgctggaagctgatg cgcaacctcctgggcacccacctgggccacagcgccatctaccacatgtgccgcatcatg gaagacagagcctacatggaggacgcaccactgctgagaggagccgtgttctttgttggc atggctctctggggtgcccaccggctctattctctcaagaactccccaacatctgtgttg ccatcgttttatgaggccatgacctgtccgaatgaggtggtgtcctacgagattgtcctc tccataaccagactcatcaagaagtacaggagggagctccaggccgtgacctgggacatc ctgctgaacatcatcgagcgcctgctccagcagctccagagcctggacagcccagagctg agcgccatcgtgcacgatctgctgagcacagtggaggagctgtgtgaccagaacgagttt cacggctcccaggagagatactttgaactcgtggagaggtgtgcggaccagaggcctgag tcatcccttttaaacttaataacctacagggctcagtccatccatccagcgaaggacggc tggatccacaacctgcagctgctgatggagaggtttttcaggaacgagtcacgcagtgcc gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctac gaggaggagcttatcaactcagtggtcatctcgcagctctcccacatccctgaggataga gaccaccaggtccggaagctggccactcagctgctggtagatctggccgaaggctgccac acccaccacttcaacagcctgctggacattgttgagaaggtgatcgcccgttccctctct ccgccccccgagctggaggagagggatgtggccgcgtactcggcctccttggaggatgtg aagactgcggtcctggggctcctggtcatccttcagactaagctgtatgccctgcctgcc agccatgccacacgcgtgtacgagacgctggtcagccacattcagctccactacaagcac agctacaccctgcccatcgccagcagcatccgtctgcaggccttcgacttcctgctgcag ctgcgggccgactcactgcaccgcctgggcctgcccagcaaagacgggcttgtgaggttc agcccctactgcgtctgtgactgcctggagacagagaggagctccgagaagaaggccggg tgccccctgtccccgcccgccgggccccctggccctgcgcctgcgggccctgccgtgcgc cttgggtccctgccctactccctgctcttccgtgttctgctgcagtgtctgaagcaggag accgactggaaggtgctgaagctggtgctcagcaaactgcccgagtcgctgcgctataag gtcctcatcttcacctccccatgcagtgtcgaccagctgtccgccgccctctgctccatg ctttcaggtcccaagaccctggagcggctccgaggcactccagaaggcttctccagaacc gacctgcatctcgctgtggttcccgtgctgacagccctgatctcttaccataactacttg gacaaaactagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgt gccagccagtgtgtggtggccctggccgtgtgcagcgtggagatgcccgacgtcatcctc aaggcactgcccgtcctggttgtgaagctcacacacatctcggccacggccagcatggcc atcccgctcctcgagttcctgtccactctggccagactgcctcacctctacaggaacttc gcagcagagcagtatgccagtgtgtttgccatctccctgccgtataccaacccctccaag ttcaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcatcaggtgc cgcctgcccttccggaaggactttgttccttacatcaccaagggtctgcgctccaacgtc ctcctgtctttcgatgacacccccgagaaggacagcttccgagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaactcaaggagagctctgcagccgatgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcaggatccagacctctctcacgagcgccagcttgggg tctgcagacgagaactcgatggcccaggccgacgacaacttgaaaaacctccacctggag ctcacagagacgtgtctggacatgatggccagatatgtgttctccaacttcacggcggtc cccaagaggtcccccgtgggagagttcctcctggctggtggcaggaccaaaacctggctg gttgggaacaagcttgtcaccgtgacgacaagcgtggggaccgggacccggtcactgcta ggcctggactctggagagctgcagggtggcccggagttgagctctgaccccagcatgcat gtgagacagacaaaggaggcacccgccaagctggagtcccaagctgggcagcaggtgtac cacggagcccgggaccgggtccgctccatgtccgggggccatggccttcgagtgggtgcc ttggacgctccagcctgctacttccccagcagccccacgtccccgggctcccagaccgct ccagccagccagcccgagaaggcctcagctggcagcccgctcccagcacagaaggagaag acaaacctggccgcttacatgcccctgctgacccagggctgggcagagatcctggtccgc aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccccttctcc tcggacatcaacagcatgccgctgcaggagctgtccaatgccctcatggccgccgagcgc ttcaaggagcgccgcgacacagccctgtacaagtcgctgtcggtgccggcggccggctca gccaagccatccccgcccccacgctccaacacagtggcctctttctcctccctgtgccag tccaggtgccaaggaaagctgcacaggagcatttcctgggcagattctgcggtggtcctg gaggagggaggtccaggtgaggctggtttgtctgcagagcctcccgagttggaagatttt gaggcgacactgggctccgacgggcgctgtgggcgcagcgacgctttcagcaggtcatct tccacctccagccaggaggagaagtcattccatgccgaggagttgcctcctgggggcatc cccatcgagcgggcggtctcggagggctcccgggcctccgtggacctcgccttccagccc tctcagcccctgagcaagtccagctcgtcgcctgaactgcagaccctgcaggacatcctg ggggaccccggggacaaggctgaggttggccggctgagccccgaggccaaggcccggtcg cagtcagggatcctggacggggaaggtgccgcctggtcagccccgggtgaggaacgccgg ggtcggggccctgcccagccagagggccccctgccttccagctgtcctcgctcccccagc gggctgcggccccgaggctacaccatctcggattcggccccgtcacgcaggggcaagagg gtggagagggatgccttcaagaaccgagcagggacctccaacaccgagaaggtgccaggc atcaaccccagcttcgtgttcctgcagctctaccactcaccgttctttggtgacgagtcc aacaagccaatccttttgcctaacgagtctttcgaacgatcagtgcagctccttgatcag atcccgtcgtacgacacgcacaagatcgcggtcctgtacgtgggagaaggccagagcaac agcgagctcgccatcctgtccaacgagcatggctcctacaggtacacagagttcctcacg gggctgggcaagctcatcgagctcaaggactgccagccggacaaggtgtacctgggcggc ctggacgtgtgcggcgaggatggccagttcacctactgctggcacgacgacatcatgcaa gctgtcttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgctgtgac aagaagcgccacctgggcaacgacttcgtgtccatcgtctacaacgactctggcgaggac ttcaagttgggcaccatcaagggccaattcaacttcgtccacgtgattatcacgcccctg gactacgagtgcaacctggtgtctctgcagtgcaggaaagacatggagggccttgtggat accagcatggccaagatcgtgtctgaccgaaacctgcccttcgtggcccgccagatggcc ctgcacgccaatatggcctcgcaggtgcaccatagccgctccaatcccaccgacatttat ccctccaagtggattgccaggctccgccacatcaagcggctgcgccagcggatccgtgag gaagcccactactcaagcgccagcctgcccctgatgcagacacaccctcctggtcatgcc aaggctccggcacaggccccggccgagtccacgcccacctatgagacgggccagcggaaa cgcctggtctcctctgtggacgacttcactgagttcgtgtga

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