Bos javanicus (banteng): 133244473 Help Entry 133244473         CDS       T11659                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism bjv  Bos javanicus (banteng) Pathway bjv01521   EGFR tyrosine kinase inhibitor resistance bjv04151   PI3K-Akt signaling pathway bjv04217   Necroptosis bjv04380   Osteoclast differentiation bjv04550   Signaling pathways regulating pluripotency of stem cells bjv04620   Toll-like receptor signaling pathway bjv04621   NOD-like receptor signaling pathway bjv04630   JAK-STAT signaling pathway bjv04658   Th1 and Th2 cell differentiation bjv04659   Th17 cell differentiation bjv05140   Leishmaniasis bjv05145   Toxoplasmosis bjv05152   Tuberculosis bjv05160   Hepatitis C bjv05161   Hepatitis B bjv05162   Measles bjv05163   Human cytomegalovirus infection bjv05164   Influenza A bjv05165   Human papillomavirus infection bjv05166   Human T-cell leukemia virus 1 infection bjv05167   Kaposi sarcoma-associated herpesvirus infection bjv05168   Herpes simplex virus 1 infection bjv05169   Epstein-Barr virus infection bjv05171   Coronavirus disease bjv05200   Pathways in cancer bjv05203   Viral carcinogenesis bjv05212   Pancreatic cancer bjv05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:bjv00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     133244473 (JAK1)    04151 PI3K-Akt signaling pathway     133244473 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     133244473 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     133244473 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     133244473 (JAK1)    04621 NOD-like receptor signaling pathway     133244473 (JAK1)    04658 Th1 and Th2 cell differentiation     133244473 (JAK1)    04659 Th17 cell differentiation     133244473 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     133244473 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     133244473 (JAK1)    05203 Viral carcinogenesis     133244473 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     133244473 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     133244473 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     133244473 (JAK1)    05161 Hepatitis B     133244473 (JAK1)    05160 Hepatitis C     133244473 (JAK1)    05171 Coronavirus disease     133244473 (JAK1)    05164 Influenza A     133244473 (JAK1)    05162 Measles     133244473 (JAK1)    05168 Herpes simplex virus 1 infection     133244473 (JAK1)    05163 Human cytomegalovirus infection     133244473 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     133244473 (JAK1)    05169 Epstein-Barr virus infection     133244473 (JAK1)    05165 Human papillomavirus infection     133244473 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     133244473 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     133244473 (JAK1)    05140 Leishmaniasis     133244473 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     133244473 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bjv01001]     133244473 (JAK1) Enzymes [BR:bjv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      133244473 (JAK1) Protein kinases [BR:bjv01001]  Non-receptor tyrosine kinases   JAK family [OT]    133244473 (JAK1) SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  133244473 NCBI-ProteinID:  XP_061267703 LinkDB All DBs Position 3:80661025..80800316 Genome browser AA seq 1158 aa AA seqDB search MQYLNIKEDCSAMAFCAKMRSSKKAEMNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTVTVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN RFHPNDSGNVLCYEVMVTGNLGIQWRQKPHIVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGIQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYTMSQLSFDRILKKDITQGEHLGRGTRTHIYSGT LTDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQHMRKCWEFQPSNRTT FQNLIEGFEALLRSMSNI NT seq 3477 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcagtgccatggctttctgtgctaaaatgagg agctccaagaaggcggagatgaatctggaggcccctgagccgggggtggaggtgctcttc tacctgtcggatagggagcctctccggctgggcggtggagagtacacggcggaggagctg tgcatccgggcggcgcaggagtgctgtatctctcctctgtgtcacaacctctttgccctg tatgacgagaacaccaagctctggtatgctccgaatcgcaccgtcaccgtcgacgacaaa acgtcactccggcttcactaccggatgaggttctatttcaccaactggcatgggaccaac gacaatgaacaatcagtatggcgacattctccaaagaagcagaaaaacggctacgagaaa aaaaaagttccagatgcaacacctctccttgatgccagctcgctggagtatctgtttgct cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag gatgggcacgacattgagaacgagtgtcttgggatggccgtgctggccatctcccattac gccatgatgaagaagatgcaattgccagaactccccaaggacattagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggattttctaaaggagtttaacaacaagaccatttgtgacagcagc gtgtccacgcacgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat cggttccatccaaatgatagtggaaatgttctctgctatgaagtgatggtgactggaaat cttggaatccagtggagacagaaaccacatattgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggaaaaaaacaaaatccga gaagagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgag gaggccttgtccttcgtgtccctggtcgatggctacttccggctcacggcagacgcccat cactacctctgcactgacgtggctcccccattgatcgtccacaacatacagaatggctgt catggtccaatctgcacggagtatgccatcaataagctgcggcaggaggggagcgaggag gggatgtacgtgctgcggtggagctgcaccgactttgacaacatcctcatgaccgtcacc tgcttcgaaaagtctgaggtgctgggtatccagaaacagttcaagaactttcagatcgag gtgcagaagggccgctacagcctgcatggctcggaccgcagcttcccgagccttggggac ctcatgagccacctaaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc caggagtggcagcctgtctacaccatgagccagctgagtttcgatcgaatcctcaagaaa gatattacgcaaggcgagcaccttgggagaggcacgcggacacacatctactctgggacc ctcacggattacaaggatgatgaagggacttctgaagagaagagaataaaagtcatcctg aaggtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctatggggtttgcgtccgagatgtg gagaatatcatggtggaagagtttgtggaggggggacccctggacctcttcatgcatcgg aaaagtgacgtcctcaccacaccctggaagtttaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagacctggtccacggaaatgtgtgcactaaaaacctcctt ctggcccgcgagggcatcgacagtgagtgcggccccttcatcaagctcagtgaccctggc atccccatcactgtgctctccaggcaagagtgcatagaacgaatcccctggattgctccc gagtgtgttgaagactccaagaatctgagtgtggctgctgacaagtggagctttggaacc acactctgggaaatctgctacaatggcgagatccccttgaaagacaagacgctgattgag aaagagagattctatgaaagccggtgcaggccagtgaccccatcttgtaaggagctagct gacttgatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc atgagagacatcaataagctggaggagcagaatccagacattgtatcagaaaaaaagcca acaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca ggggagcaagtggctgtcaaatccctgaagcccgagagtggagggaaccacatcgctgat ctgaagaaggagattgaaatcttaagaaatctttatcatgagaacattgtgaagtataaa ggcatctgcacagaagatggtggaaacggtattaagctcatcatggagtttctgccttca gggagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta aaatatgccgttcagatttgtaaggggatggactatctgggttctcggcagtacgttcac cgggacttagcagcaagaaacgtcctcgtggagagtgagcaccaggtgaaaatcggggac ttcggtctcaccaaagccatcgaaactgataaggagtactacacagtcaaggacgaccgg gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttctatatcgcc tctgatgtctggtctttcggagtgactctgcatgagctgcttacttactgtgattcagat tccagtcccatggccttgttcctgaaaatgataggcccaactcatggtcagatgacggta acaagactcgtgaatacattaaaagaaggaaaacgcttgccatgtccaccgaactgtcca gatgaggtttatcaacatatgcgaaagtgttgggaatttcaaccatctaatcggacaacc tttcagaaccttattgaaggatttgaagcacttctaagaagcatgagtaacatttaa

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