KEGG T11435: 129646058

Bubalus kerabau (carabao): 129646058

Entry

129646058         CDS       T11435

Symbol

HSD17B8

Name

(RefSeq) (3R)-3-hydroxyacyl-CoA dehydrogenase isoform X1

K13370

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Organism

bke Bubalus kerabau (carabao)

Pathway

bke00061

Fatty acid biosynthesis

bke00140

Steroid hormone biosynthesis

bke01100

Metabolic pathways

bke01212

Fatty acid metabolism

Module

bke_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:bke00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    129646058 (HSD17B8)
   00140 Steroid hormone biosynthesis
    129646058 (HSD17B8)
Enzymes [BR:bke01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     129646058 (HSD17B8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     129646058 (HSD17B8)

SSDB

Motif

Pfam:

adh_short_C2 adh_short KR Epimerase RmlD_sub_bind ALOG_dom

Other DBs

NCBI-GeneID:

129646058

NCBI-ProteinID:

XP_055427703

LinkDB

Position

AA seq 266 aa
MASPLRLRSALALVTGAGGGLGRAISVRLAAEGAAVAACDLDGAAARETVRLLGGPGTEE
GAPRGAHAAFQADVSEAGAARRLLEQVQACFSRPPSVVVSCAGITRDEFLLHMSEDNWDK
VIAVNLKGIFLVTQAAAQALVSSGCPGSIINISSIIGKVRLSWEEVGNMGQTNYAASKAG
VIGLTQSAARELGRHGIRCNSVLPGFIRTPMTQKVPQKVLDKVTGMIPMAHMGNPEDVAD
VIAFLASEDSGYITGASVEVTGGLFM

NT seq 801 nt +upstreamnt +downstreamnt
atggcgtctccgctccgattgcgctccgcgctggccctggttacaggtgcgggcggcggc
cttggccgcgccatcagcgtgcgcctcgccgccgagggggccgccgtagccgcttgcgac
ctggacggggcagcagcgcgggagacggtgcggctgctgggagggccggggaccgaggag
ggggcgccccgcggagcccacgccgccttccaggctgatgtgtccgaggcaggggccgct
aggcgcctgctggagcaagtgcaggcctgcttttctcgcccgccgtctgtcgttgtgtcc
tgtgcgggcatcaccagggatgaatttctactccacatgtctgaggacaactgggacaaa
gtcatagctgtcaacctcaagggcatctttctagtcactcaggctgcagcccaagccctc
gtgtccagcggctgtcctggctccatcatcaacatcagtagcatcataggcaaggtcagg
ctgagctgggaggaggtggggaacatgggacagacgaactatgcagcatccaaggctgga
gtgattgggctgacccagtctgcagcccgggaacttggacgacacgggatccgctgtaac
agtgtcctcccaggattcattagaacacccatgacccagaaagtgccgcagaaagtgctg
gacaaggtgactggaatgatcccaatggcacatatggggaaccctgaggatgtggcagat
gtcatcgcattcttggcatctgaagacagtggatacatcacaggggcatcagtggaagtc
actggaggtcttttcatgtaa

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