Bubalus kerabau (carabao): 129649034
Help
Entry
129649034 CDS
T11435
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
bke Bubalus kerabau (carabao)
Pathway
bke01521
EGFR tyrosine kinase inhibitor resistance
bke01522
Endocrine resistance
bke01524
Platinum drug resistance
bke04010
MAPK signaling pathway
bke04012
ErbB signaling pathway
bke04020
Calcium signaling pathway
bke04066
HIF-1 signaling pathway
bke04151
PI3K-Akt signaling pathway
bke04510
Focal adhesion
bke04518
Integrin signaling
bke04520
Adherens junction
bke04530
Tight junction
bke05200
Pathways in cancer
bke05205
Proteoglycans in cancer
bke05206
MicroRNAs in cancer
bke05212
Pancreatic cancer
bke05213
Endometrial cancer
bke05215
Prostate cancer
bke05219
Bladder cancer
bke05223
Non-small cell lung cancer
bke05224
Breast cancer
bke05226
Gastric cancer
bke05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bke00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129649034 (ERBB2)
04012 ErbB signaling pathway
129649034 (ERBB2)
04066 HIF-1 signaling pathway
129649034 (ERBB2)
04020 Calcium signaling pathway
129649034 (ERBB2)
04151 PI3K-Akt signaling pathway
129649034 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
129649034 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
129649034 (ERBB2)
04520 Adherens junction
129649034 (ERBB2)
04530 Tight junction
129649034 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129649034 (ERBB2)
05206 MicroRNAs in cancer
129649034 (ERBB2)
05205 Proteoglycans in cancer
129649034 (ERBB2)
05230 Central carbon metabolism in cancer
129649034 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
129649034 (ERBB2)
05226 Gastric cancer
129649034 (ERBB2)
05219 Bladder cancer
129649034 (ERBB2)
05215 Prostate cancer
129649034 (ERBB2)
05213 Endometrial cancer
129649034 (ERBB2)
05224 Breast cancer
129649034 (ERBB2)
05223 Non-small cell lung cancer
129649034 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129649034 (ERBB2)
01524 Platinum drug resistance
129649034 (ERBB2)
01522 Endocrine resistance
129649034 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bke01001
]
129649034 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
bke04147
]
129649034 (ERBB2)
04090 CD molecules [BR:
bke04090
]
129649034 (ERBB2)
Enzymes [BR:
bke01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129649034 (ERBB2)
Protein kinases [BR:
bke01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
129649034 (ERBB2)
Exosome [BR:
bke04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
129649034 (ERBB2)
CD molecules [BR:
bke04090
]
Proteins
129649034 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
APH
CcmD
Motif
Other DBs
NCBI-GeneID:
129649034
NCBI-ProteinID:
XP_055431958
LinkDB
All DBs
Position
4:complement(24150343..24174815)
Genome browser
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPADASLSFLQEIQEVQGYVLIAHNRVSQVPLQRLRIVRGTQLFEERYALAVLDNG
DFLESAAPAAGTAPGGLQELQLRSLTEILKGGVLIQRNPQLCHQDTILWEDIFHKNNQLP
LKQIDTNRSRACAPCSPVCKAPNCWGESSEDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCAPVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFAGDPDSNIAPLQAEQLKVFESLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFQNPHQALLHSANRPEDECVGEGLACYPLCAQGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHPECHPQNGSVTCFGSEADQCVACAHYKDLPFCVARC
PSGVKPDLSFMPIWKFPDEEGICQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
VLLVVLVGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDMGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAAGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQPLPQHDSSPLQRYSEDPTVPLSPEADGYVAPLTCSPQPEYV
NQPEVHPQPPSPLEGPLPPPRPAGSTLERPKTLSPGKNGVVKDVFAFGAAVENPEYLAPR
GRAAPQSHSSPAFSPAFDNLYYWDQDPSERGTPPSTFEETPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctaccggccagtcccgag
acccacctggacatgctgcgccacctctaccaaggctgtcaggtggtgcagggtaacctg
gagctcacctacctgcctgctgatgccagcctctccttcctgcaggaaatccaggaggtg
cagggctatgtgctcatcgctcacaatcgagtgagtcaggtcccactgcagagactgcga
attgtgcgaggcacccagctttttgaggaacgctacgccctggccgtgctggacaatgga
gactttctggaaagtgctgcccctgctgcaggcacagccccaggagggctgcaggagctg
cagctgcgaagcctcacagagatcctcaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattttgtgggaggatatcttccacaagaacaaccagctgccc
ctcaagcagatagacaccaaccgctcacgggcctgcgcaccttgttctccagtttgtaaa
gctcccaactgctggggagaaagttctgaggactgtcagagcttgacgcggaccgtctgt
gccagtggctgtgcccgctgtaagggcccacagcccaccgactgctgccatgagcagtgc
gctgctggctgtactggccccaagcactctgactgcctggcctgcctccacttcaaccac
agcggcatctgcgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tccatgcccaaccccgaggggcgttataccttcggtgccagctgtgtgacggcctgtcct
tacaactacctgtctacggatgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagaggtgtgagaaatgcagcaagccctgtgcccca
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggagtttgctggctgcaagaagatttttgggagcctggcgtttctgccagagagc
tttgcaggggacccagactctaacatcgccccgctgcaggctgagcagctcaaagtgttt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgcct
gacctcagcgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctccctgagggaa
ctgggcagcgggctggctctcatccaccgcaacgcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccagaacccccaccaggctctgctccacagcgccaacaggcca
gaggatgagtgcgtgggcgagggcctggcgtgctacccactgtgcgcccaagggcactgc
tggggtcccgggcccacccagtgcgtcaactgcagccagttccttcggggccaggaatgc
gtggaggaatgccgagtactgcaggggctcccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccccgagtgtcatccccagaatggctcagtgacctgctttggctcggag
gctgaccaatgtgtggcttgtgcccactacaaggatcttcctttctgcgtggctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagtttccagatgaggag
ggcatatgccagccatgccccatcaactgcacccactcctgtgtggacttggatgacaag
ggctgccccgccgagcagagagccagccctgtgacatccatcattgccgctgtggtgggc
gttctgctggttgtccttgtggggctggtgttcggcatcctcattaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacggagctggtggagcccctg
acgcccagcggagcgatgcccaatcaggctcagatgcggatcttaaaagagacagagctg
aggaaggtgaaggtgctaggatctggagcttttggcaccgtctacaagggcatctggatc
cccgatggggaaaatgtgaaaatccccgtggccatcaaggtgttgagggaaaacacatct
cccaaagccaacaaggaaatcttggacgaagcatatgtgatggctggtgtaggctcccca
tatgtgtcccgcctcctgggcatctgcctgacatccacagtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgttcgagaacaccgtgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgtgcgg
ctcgtgcatagggacctggccgcccggaacgtgctggtcaagagtcccaaccatgtgaag
attacagacttcgggctagctcggctgctagacattgacgagacagagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcattggagtccatcctccggcggcggttcacc
caccagagtgacgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggagaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttagtggctgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacatgggccctgctagccccctg
gatagcaccttctaccgctcgctgctggaggatgacgacatgggcgacctggtggatgcg
gaggagtacctggtgccccagcagggcttcttctgcccagaccctgccccgggtgctgca
ggcacagcccatcgcaggcaccgcagcacatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctctgaggaggagcctcccagatctccgctggcaccttccgaaggg
gcaggctctgatgtgtttgatggcgacttgggaatgggggcggccaaggggctgcagccc
ctcccccaacatgactctagtcctctacagcggtacagcgaggaccccacagtacccctt
tctcccgaggctgatggctacgttgcccccttgacctgcagcccccagccggaatatgtg
aaccagccagaggttcacccacagcccccctcgcccctagagggtcctctgccacctcct
cgacctgccggttccactctggaaaggcccaagacgctctcccctgggaagaatggggtt
gtcaaagacgtttttgcctttggggctgccgtggagaaccctgagtacttggcaccccgg
ggcagggctgcccctcagtcccactcttctccagccttcagcccagcctttgacaacctc
tattattgggaccaggacccatcagagcggggcactccacccagcacctttgaagagacc
cctacggcagagaaccctgagtacctgggtctggacatgccagtatga
DBGET
integrated database retrieval system
