Burkholderia mallei 6: DM78_741
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Entry
DM78_741 CDS
T03489
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bmae
Burkholderia mallei 6
Pathway
bmae00290
Valine, leucine and isoleucine biosynthesis
bmae00620
Pyruvate metabolism
bmae01100
Metabolic pathways
bmae01110
Biosynthesis of secondary metabolites
bmae01210
2-Oxocarboxylic acid metabolism
bmae01230
Biosynthesis of amino acids
Module
bmae_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bmae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DM78_741 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DM78_741 (leuA)
Enzymes [BR:
bmae01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DM78_741 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
BP74_N
Motif
Other DBs
NCBI-ProteinID:
AIO58491
UniProt:
A0AAX1X7B5
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Position
1:complement(819060..820700)
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AA seq
546 aa
AA seq
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MKRNPAEKYRPFEPVRINGRRWPSRAIERAPIWMSTDLRDGNQSLIEPMTIEQKLEYFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIVERRIPDDVTIEVLVQSREDLIARTFDALEGA
PRAIVHLYNAICPSFRRIVFGMSKDDVKALAVDGTRIIKAHAQARPATHWTFQYSPETFS
MTELPFAREVCDAVAQTWRPTRDHKMIVNLPATVEAATPNVFADQIEWMDRNLGYRDSIV
LSVHPHNDRGTAVAAAELALLAGAERIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNRIPVHPRHPYAGDLVFTAFSGSHQDAIRKGLAQQRPDAIWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATYLLERAMGFAPPRRVQIEFSHAVQTLADTSGAE
VTADAICALFTREYLQTIGPAARAGASASWHDREVALAHAEDAPSAARQAAAAFASAAGV
AIDITSCEVERTVNGETAVFVGARIGDAALRHGAGVHRDPVAAATDAVASAINRSAWSRD
KRRAAA
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcaaccccgccgagaaataccgaccgttcgaacccgttcgcatcaacggacgc
cgatggccgagccgcgcgatcgagcgcgcgccgatctggatgagcaccgatctgcgcgac
ggcaaccagtcgctgatcgagccgatgacgatcgagcagaagctcgaatacttcgagatg
ctcgtcgcgatcggcttcaaggaaatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtgcgcaagctgatcgtcgagcggcgcattcccgacgatgtgacgatcgaa
gtgctcgtgcaatcgcgcgaagacctgatcgcgcgcacgttcgacgcgctcgaaggcgcg
ccgcgcgcgatcgtccacctgtacaacgcgatctgcccgtcgttccgccggatcgtgttc
gggatgtcgaaggacgacgtgaaggcgctcgcggtggacggcacgcggatcatcaaggcg
cacgcgcaggcgcgccccgccacccactggacgttccagtactcgcccgagacgttcagc
atgaccgagctgccgttcgcgcgggaggtctgcgacgccgtcgcgcagacgtggcggccg
acgcgcgatcacaagatgatcgtgaacctgcccgccaccgtcgaggccgcgacgccgaac
gtgttcgccgaccagatcgaatggatggaccgcaatctcggctatcgcgacagcatcgtg
ctgtccgtgcatccgcacaacgaccgcggcacggcggtcgcggcggccgagctcgcgttg
ctcgcgggcgcggagcgcatcgaaggatgcctgttcggcaacggcgagcgcacgggcaac
gtcgatctcgtcacgctcgcgctgaacctgtacacgcaggggatcgatccgggcctcgat
ttctccgatatcgacgcggtgcgccgcgtcgtcgagcgctgcaaccggattcccgtgcat
ccgcgccatccgtacgcgggcgacctcgtgttcaccgcgttctccggctcgcatcaggac
gcgatccgcaagggcctcgcgcagcagcggcccgatgcgatctgggaagtgccgtacctg
ccgatcgatcccgccgacctcggccgcagctacgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgacctatctgctcgagcgcgcaatgggtttcgcgccgccgcgc
cgcgtgcagatcgaattcagccatgcggtgcaaacgctcgccgacacgtccggcgcagag
gtgacggccgatgcgatttgcgcgctcttcacgcgcgaatatctgcagacgatcggcccg
gccgcgcgcgcgggcgcgtcggcgagctggcacgatcgcgaagtcgcgctcgcgcacgcc
gaggatgcgccgagcgcggcgcggcaggcggcggccgcgttcgcgtcggccgcgggcgtc
gcgatcgacatcacgtcgtgcgaggtcgagcgcaccgtgaacggcgagaccgccgtgttc
gtcggcgcgaggatcggcgacgccgcgttgcgccacggcgcgggcgtgcatcgcgacccg
gtcgcggccgcgacggacgccgtcgcgagcgcgatcaaccgctcggcgtggagccgcgac
aagcggcgcgccgcggcctga
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