KEGG   Burkholderia mallei FMH 23344: DM51_2731
Entry
DM51_2731         CDS       T03523                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
bmaf  Burkholderia mallei FMH 23344
Pathway
bmaf00290  Valine, leucine and isoleucine biosynthesis
bmaf00620  Pyruvate metabolism
bmaf01100  Metabolic pathways
bmaf01110  Biosynthesis of secondary metabolites
bmaf01210  2-Oxocarboxylic acid metabolism
bmaf01230  Biosynthesis of amino acids
Module
bmaf_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:bmaf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    DM51_2731 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DM51_2731 (leuA)
Enzymes [BR:bmaf01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     DM51_2731 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 BP74_N
Other DBs
NCBI-ProteinID: AIP78065
UniProt: A0AAX1X7B5
LinkDB
Position
1:3023968..3025608
AA seq 546 aa
MKRNPAEKYRPFEPVRINGRRWPSRAIERAPIWMSTDLRDGNQSLIEPMTIEQKLEYFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIVERRIPDDVTIEVLVQSREDLIARTFDALEGA
PRAIVHLYNAICPSFRRIVFGMSKDDVKALAVDGTRIIKAHAQARPATHWTFQYSPETFS
MTELPFAREVCDAVAQTWRPTRDHKMIVNLPATVEAATPNVFADQIEWMDRNLGYRDSIV
LSVHPHNDRGTAVAAAELALLAGAERIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNRIPVHPRHPYAGDLVFTAFSGSHQDAIRKGLAQQRPDAIWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATYLLERAMGFAPPRRVQIEFSHAVQTLADTSGAE
VTADAICALFTREYLQTIGPAARAGASASWHDREVALAHAEDAPSAARQAAAAFASAAGV
AIDITSCEVERTVNGETAVFVGARIGDAALRHGAGVHRDPVAAATDAVASAINRSAWSRD
KRRAAA
NT seq 1641 nt   +upstreamnt  +downstreamnt
atgaagcgcaaccccgccgagaaataccgaccgttcgaacccgttcgcatcaacggacgc
cgatggccgagccgcgcgatcgagcgcgcgccgatctggatgagcaccgatctgcgcgac
ggcaaccagtcgctgatcgagccgatgacgatcgagcagaagctcgaatacttcgagatg
ctcgtcgcgatcggcttcaaggaaatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtgcgcaagctgatcgtcgagcggcgcattcccgacgatgtgacgatcgaa
gtgctcgtgcaatcgcgcgaagacctgatcgcgcgcacgttcgacgcgctcgaaggcgcg
ccgcgcgcgatcgtccacctgtacaacgcgatctgcccgtcgttccgccggatcgtgttc
gggatgtcgaaggacgacgtgaaggcgctcgcggtggacggcacgcggatcatcaaggcg
cacgcgcaggcgcgccccgccacccactggacgttccagtactcgcccgagacgttcagc
atgaccgagctgccgttcgcgcgggaggtctgcgacgccgtcgcgcagacgtggcggccg
acgcgcgatcacaagatgatcgtgaacctgcccgccaccgtcgaggccgcgacgccgaac
gtgttcgccgaccagatcgaatggatggaccgcaatctcggctatcgcgacagcatcgtg
ctgtccgtgcatccgcacaacgaccgcggcacggcggtcgcggcggccgagctcgcgttg
ctcgcgggcgcggagcgcatcgaaggatgcctgttcggcaacggcgagcgcacgggcaac
gtcgatctcgtcacgctcgcgctgaacctgtacacgcaggggatcgatccgggcctcgat
ttctccgatatcgacgcggtgcgccgcgtcgtcgagcgctgcaaccggattcccgtgcat
ccgcgccatccgtacgcgggcgacctcgtgttcaccgcgttctccggctcgcatcaggac
gcgatccgcaagggcctcgcgcagcagcggcccgatgcgatctgggaagtgccgtacctg
ccgatcgatcccgccgacctcggccgcagctacgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgacctatctgctcgagcgcgcaatgggtttcgcgccgccgcgc
cgcgtgcagatcgaattcagccatgcggtgcaaacgctcgccgacacgtccggcgcagag
gtgacggccgatgcgatttgcgcgctcttcacgcgcgaatatctgcagacgatcggcccg
gccgcgcgcgcgggcgcgtcggcgagctggcacgatcgcgaagtcgcgctcgcgcacgcc
gaggatgcgccgagcgcggcgcggcaggcggcggccgcgttcgcgtcggccgcgggcgtc
gcgatcgacatcacgtcgtgcgaggtcgagcgcaccgtgaacggcgagaccgccgtgttc
gtcggcgcgaggatcggcgacgccgcgttgcgccacggcgcgggcgtgcatcgcgacccg
gtcgcggccgcgacggacgccgtcgcgagcgcgatcaaccgctcggcgtggagccgcgac
aagcggcgcgccgcggcctga

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