Burkholderia mallei NCTC 10247: BM44_1896
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Entry
BM44_1896 CDS
T03524
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
bmaz
Burkholderia mallei NCTC 10247
Pathway
bmaz00230
Purine metabolism
bmaz01100
Metabolic pathways
bmaz01110
Biosynthesis of secondary metabolites
Module
bmaz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
bmaz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
BM44_1896 (purL)
Enzymes [BR:
bmaz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
BM44_1896 (purL)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
SMC_hinge
Motif
Other DBs
NCBI-ProteinID:
AIS29043
LinkDB
All DBs
Position
1:2116366..2120436
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AA seq
1356 aa
AA seq
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MAHFSCFPGASALSDFRQTRLLDALKQIDGDIVAVRGQYLHFVNAHEPLTADDEARIGAL
MHYGAPLEPAAEKGATETFVVLPRFGTVSPWASKATDIARHCGLARVRRIERGIEFTVTL
KAGVLGVGAKKALAADARAAVAAALHDRMTESVVASREDARHLFDELPAKPLATVDVLAE
GRAALERANAELGLALADDEIDYLVDAFIKLERNPTDVELMMFAQANSEHCRHKIFNAQW
TIDGQAQDMSLFAMIRNTEKMSPQGTIVAYSDNSSIMSGAHAERWFPRGAGEPGEPGERY
GRHTELTHTLMKVETHNHPSAISPFPGAATGAGGEIRDEGATGRGARPKAGLTGFTVSNL
DLPGARESWENARDAAQPAAARNAQQPCAPYGRPDRIASPLSIMIDGPLGGAAFNNEFGR
PNLGGYFRVYEQNVGGQVRGYHKPIMIAGGIGNISDAHTHKHDVPAGSLLIQIGGPGMRI
GMGGGAASSMATGANTAELDFDSVQRGNPEIERRAQEVINGCWQLGEHNPILSIHDVGAG
GLSNAFPEIVDGAGKGARFELRKIALEESGLSPREIWSNEAQERYVLAISPADLPRFEAI
CARERCPFSVVGVATDERRLQLVDGEATGAAAYPVDMPMEVLLGKPPRMHRDVKRVHIER
AGVDVTGVALADAARDVLRHPTVASKSFLITIGDRTVGGTSVRDQMVGPWQVPVADCAVT
ALDYAGFAGEAMTMAERTPLAVIDAPASGRMAVGEAITNIAAAPIASLDKLKLSANWMAA
CGTEGEDAKLFDTVKAIGMELCPALGIGIPVGKDSLSMKTKWNDNGVAKEVVAPVSLIIS
AFAPVEDVRRHLTPQLRRVADVGASVLIAIDLGRGKNRLGGSILAQVTQQVGDATPDVDD
PEDLKRFFAAVQSLNARDLLLAYHDRSDGGLWATVCEMALAGHAGVSLNVDMLTLDQQHE
SDYGDAKDWAKQTSGRREDRTIRALFSEELGAVVQVRAADRDAVLGALREHGLSACSHVI
GAVNETDAIEVYRDAKKIYEAPRVELQRAWSEVSWRIARLRDNPACADAEYDAILDAGDP
GLSPVLTFDPAEDVAAPFIATGARPRVAILREQGVNSHLETAYAFDRAGFDAHDVHMSDL
LAGRATLADFAGAVACGGFSYGDVLGAGEGWAKTIRFNDKLADMFAAFFARPDTFALGIC
NGCQMMSSLASMIPGAQAWPKFTRNKSEQFEARFSFVEVQSSPSIFFAGMEGSRIPVAVA
HGEGYADFSQQGDQSRVAVAMRYVDHRGDATERYPFNPNGSPAGITSVTTADGRFTVLMP
HMERVHRTVTMSWHPQGWGEASPWLRVFRNARRWIG
NT seq
4071 nt
NT seq
+upstream
nt +downstream
nt
atggctcacttctcgtgttttcccggtgcttcggcgctttccgatttccgtcaaacccgc
ctgctcgacgcgctcaagcaaatcgacggcgacatcgtcgcggttcgcggccagtatctg
catttcgtcaacgcgcatgagccgctcaccgccgacgacgaagcgcgcatcggcgcgctg
atgcattacggcgcgccgctcgagcccgccgcggagaagggcgcgaccgagaccttcgtc
gtgctgccgcgcttcggcaccgtctcgccgtgggcgagcaaggcgaccgacatcgcgcgg
cactgcggcctggcgcgcgtgcgccggatcgagcgcggcatcgagttcacggtgacgctg
aaggcgggcgtcctgggcgtcggcgcgaagaaggcgctcgccgccgacgcgcgcgcggcg
gtcgcggccgcgctgcacgaccggatgacggaaagcgtcgtcgcgtcgcgcgaggacgcg
cggcacctgttcgacgagctgccggccaagccgctcgcgacggtcgacgtgctcgccgaa
ggccgagccgcgctcgagcgcgcgaacgccgaactcggcctcgcgctcgccgacgacgag
atcgactacctcgtcgacgcgttcatcaagctcgagcgcaacccgaccgacgtcgagctg
atgatgttcgcgcaggcgaacagcgaacactgccgccacaagatcttcaacgcgcagtgg
acgatcgacgggcaggcgcaggacatgtcgctgttcgcgatgatccgcaatacggagaag
atgagcccgcaaggcacgatcgtcgcgtattcggacaactcgtcgatcatgagcggcgcg
cacgcggagcggtggttcccgcgcggcgcgggcgagccgggcgagccgggcgagcggtat
ggccggcataccgagctcacgcatacgctgatgaaggtggagacgcacaatcacccgagc
gcgatctcgccgttccccggcgcggcgacgggcgcgggcggcgagattcgcgacgaaggc
gcgacgggccgcggcgcgcggccgaaggcgggcttgacgggcttcacggtgtcgaacctg
gatctgccgggcgcgcgcgaatcgtgggaaaacgcgcgcgacgccgcgcagccggcggcc
gcgcgcaacgcgcagcagccgtgcgcgccgtacggccgcccggaccggatcgcgtcgccg
ctgtcgatcatgatcgacggcccgctcggcggcgccgcattcaacaacgaattcgggcgc
ccgaacctgggcggctacttccgcgtgtacgagcagaacgtcggcggccaggtgcgcggc
tatcacaagccgatcatgatcgcgggcggcatcggcaacatctcggacgcgcacacgcac
aagcacgacgtgccggccggctcgctgctcatccagatcggcggcccgggcatgcgcatc
ggcatgggcggcggcgcggcgagctcgatggccaccggcgcgaacaccgccgagctcgac
ttcgattcggtccagcgcggcaacccggaaatcgagcggcgcgcgcaggaagtgatcaac
ggctgctggcagctcggcgagcacaacccgattctcagcattcacgacgtcggcgcgggc
ggtctgtccaatgcgttccccgagatcgtcgacggcgcgggcaagggtgcgcgcttcgag
ctgcgcaagatcgcgctcgaggaatcgggcctgtcgccgcgcgagatctggtcgaacgag
gcgcaggagcgctacgtgctggcaatttcgcccgccgatctgccgcgcttcgaggcgatc
tgcgcgcgcgagcgctgcccgttctcggtcgtcggcgtcgcgaccgacgagcgccgcctc
cagcttgtcgacggcgaggcgacgggcgcggccgcgtatccggtcgacatgccgatggag
gtgctgctcggcaagccgccgcggatgcaccgcgacgtgaagcgcgtgcacatcgagcgc
gcgggcgtggacgtgacgggcgtcgcgcttgccgacgccgcgcgcgacgtgctccggcac
ccgaccgtcgcgagcaagtcgttcctcatcacgatcggcgaccgcacggtgggcggcacg
tcggtgcgcgaccagatggtcggcccgtggcaggtgcccgtcgccgattgcgcggttacc
gcgctcgactacgcgggcttcgccggcgaggcgatgacgatggccgagcgcacgccgctc
gcggtgatcgacgcgccggcgtcgggccgcatggcggtgggcgaggcgatcacgaacatc
gcggccgcgccgatcgcctcgctcgacaagctgaagctgtccgcgaactggatggccgcg
tgcggcaccgagggcgaggacgcgaagctcttcgacacggtcaaggcgatcggcatggag
ctgtgcccggcgctcggcatcggcattccggtcggcaaggattcgctgtcgatgaagacg
aagtggaacgacaacggcgtcgcgaaggaagtggtcgcgccggtgtcgctgatcatctcg
gcgttcgcgcccgtcgaggacgtgcgccgccatctgacgccgcagctgcgccgcgtcgcg
gacgtcggcgcgagcgtgctgatcgcgatcgatctcgggcgcgggaagaaccgcctcggc
ggcagcattctcgcgcaggtcacgcagcaggtcggcgacgcgacgcccgacgtcgacgat
ccggaagacctgaagcgtttcttcgcggcggtccagtcgctgaatgcgcgggacctgctg
ctcgcgtaccacgaccgctcggacggcggcctgtgggcgaccgtctgcgaaatggcgctc
gccgggcacgcgggcgtgtcgctgaacgtcgacatgctgacgctcgatcagcagcacgaa
tccgactacggcgacgcgaaggactgggcgaagcagacgagcggccgccgcgaggatcgc
acgatccgcgcgctcttctccgaggaactcggcgcggtcgtccaggtgcgcgcggcggac
cgcgacgcggtgctcggcgcgctgcgcgagcatggcctgtccgcgtgctcgcacgtgatc
ggtgcggtcaacgagaccgacgcgatcgaggtgtaccgcgacgcgaagaagatctacgag
gcgccgcgcgtcgagctgcagcgcgcatggagcgaggtgagctggcggatcgcgcggctg
cgtgacaacccggcgtgcgcggacgccgagtacgacgcgatcctcgacgccggcgatccg
ggcctctcgcccgtgctgacgttcgatccggcggaggatgtcgccgcgccgttcatcgcg
acgggcgcgcgtccgcgtgtcgcgatcctgcgcgagcagggcgtgaactcgcatctcgaa
accgcctacgcgttcgaccgcgcgggcttcgacgcgcatgacgtccacatgagcgacctg
ctcgccggccgcgcgacgctcgccgatttcgccggcgcggtcgcgtgcggcggcttctcg
tacggcgacgtgctcggcgcgggcgagggctgggcgaagacgatccgcttcaacgacaag
ctcgccgacatgttcgccgcgttcttcgcgcgccccgacacgttcgcgctcggcatctgc
aacggctgccagatgatgtcgagcctcgcgtcgatgatcccgggcgcgcaggcgtggccg
aagttcacgcgcaacaagtccgagcagttcgaggcgcgtttctcgttcgtcgaagtgcaa
agctcgccgtcgatcttcttcgcgggcatggaaggctcgcggattccggtggcggtcgcg
catggcgaaggctacgcggacttctcgcagcagggcgatcagagccgcgtcgcggtcgcg
atgcgctacgtcgatcaccgcggcgacgcgaccgagcgctatccgttcaacccgaacggc
tcgcccgcgggcatcacgtcggtgacgacggcggacggccgcttcacggtgctgatgccg
cacatggagcgcgtgcatcgcacggtgacgatgagctggcatccgcagggctggggcgaa
gcgagcccgtggctgcgcgtgttccgcaacgcgcgccgctggatcggctga
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