Brucella abortus bv. 1 9-941: BruAb1_1555
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Entry
BruAb1_1555 CDS
T00241
Symbol
leuA
Name
(GenBank) LeuA, 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bmb
Brucella abortus bv. 1 9-941
Pathway
bmb00290
Valine, leucine and isoleucine biosynthesis
bmb00620
Pyruvate metabolism
bmb01100
Metabolic pathways
bmb01110
Biosynthesis of secondary metabolites
bmb01210
2-Oxocarboxylic acid metabolism
bmb01230
Biosynthesis of amino acids
Module
bmb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bmb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BruAb1_1555 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BruAb1_1555 (leuA)
Enzymes [BR:
bmb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BruAb1_1555 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AAX74882
UniProt:
Q57BV2
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Position
I:complement(1533945..1535672)
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AA seq
575 aa
AA seq
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MNQPVSTPKSVSQAVSARKGMPIAGTKYAPFPAPQLDDRTWSSKRIEKAPIWCSVDLRDG
NQALIDPMGHDRKERMFRLLIDMGFPEIEIGFPSASQTDFDFCRWAIEQGDVPDDVDLQV
LVQCRPELITRTFEALEGAKTPIIHFYNSTSELQRRVVFAKDVGGIKQIATDAAKMIMDM
AAKAGGGYRFQYSPESFTGTELDVALEICNAVIEIVKPTPDNKLIVNLPSTVEMNTPNVY
ADQIEWMCRNLDNRESLIISLHPHNDRGTGIAATELGLMAGADRVEGTLFGNGERTGNVD
VVTLALNMYTQGIDPGLDCTDINRMKEVYEYSNQLKIAERHPYVGELVYTAFSGSHQDAI
NKGMKARRSANSPVWEVPYLPIDPQDVGRSYEAIIRINSQSGKGGIAYILQADYGLNLPR
NLQVEFREIIQHITDEEGKELPSKRIYEEFQKLYVTQPDARIKFVDHHTYPDPEQKGRRI
LTAEITDNGVTKTIEGKGTGPIDGFVDALSKYLGVKMSVVDYSEHSLQQGSDASAISYVE
MVYPGGKLFGVGINDNIVSASLEAVVSAANRVIAK
NT seq
1728 nt
NT seq
+upstream
nt +downstream
nt
atgaaccagcctgtctccacgccaaagtccgtgtcccaagccgtatcggcacgcaagggc
atgcctattgccggtaccaaatacgcgccgttccctgcgccgcagctcgatgaccgcact
tggtcttccaaacgcatcgaaaaggcgccgatctggtgttcggtcgatctgcgcgacggc
aaccaggctttgatcgaccccatggggcatgaccgcaaggagcgcatgttccgcctgctg
atcgatatgggtttcccggaaatcgagatcggtttcccgtccgcttcgcagacggatttc
gacttctgccgctgggccattgaacagggcgatgttcctgacgacgtggatttgcaggtt
ctggtccagtgccgtcctgaattgattacgcgcactttcgaggcgctggaaggcgcgaag
acgccgatcatccatttctacaattccaccagcgaattgcagcgccgcgtggtgtttgcc
aaggatgtcggcggcatcaagcagattgcaaccgatgcggccaagatgatcatggatatg
gctgccaaggctggcggcggttatcgcttccagtattcgccggaaagctttaccggcacc
gaactggatgtggcgctggaaatctgcaatgcggtgatcgagatcgtgaagccgacgccg
gacaacaagctgatcgtcaacctgccttcgacggtggagatgaacacgccgaatgtctat
gccgaccagatcgaatggatgtgccgcaatctggacaatcgcgagagcctgattatctcg
ctgcatccgcataatgaccgcggcacgggcattgccgccactgaactgggcctgatggca
ggcgctgatcgcgtggaaggcacgctgttcggcaatggcgagcgcacgggcaatgtggat
gtggtgacgctggcgctcaacatgtacacgcagggcatcgaccccgggctggattgcacc
gatatcaaccggatgaaggaagtctacgaatattccaaccagttgaagatcgccgagcgc
catccttatgtgggcgagctggtctatacggctttctccggctcgcatcaggatgcgatc
aacaagggcatgaaagcgcgccgttcggccaattcgccggtttgggaagttccttacctg
ccgatcgatccgcaggatgtgggccgctcctacgaggcgatcatccgcatcaattcgcaa
tcgggcaagggcggtatcgcctatatcctgcaagccgattacggcctgaacctgccgcgc
aacctgcaggtcgagttccgcgaaatcatccagcacattacggatgaagagggcaaggag
ctgccatcgaagcgcatttacgaggagttccagaaactctatgtgacgcagcccgatgcc
cgcatcaagttcgtggatcaccacacctatcccgatcctgagcaaaagggccggcgcatc
ctgacggctgagatcaccgataacggtgtcaccaagactatcgagggcaagggcacggga
ccgatcgatggtttcgtggatgcgctgtcgaaatatcttggcgtgaaaatgtcggtggtc
gattattccgaacattcgctccagcagggttcggatgcttcggccatttcctatgtcgag
atggtttatcccggcggcaagctgttcggtgtcggcatcaacgataatatcgtcagcgcc
tcgcttgaagccgtggtgtcggcggcaaatcgtgtgattgctaagtag
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