Brucella melitensis bv. 1 16M: BMEI0575
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Entry
BMEI0575 CDS
T00072
Name
(GenBank) udp-n-acetylmuramoylalanyl-d-glutamyl-2,6-diaminopimelate--d-alanyl-d-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bme
Brucella melitensis bv. 1 16M
Pathway
bme00300
Lysine biosynthesis
bme00550
Peptidoglycan biosynthesis
bme01100
Metabolic pathways
bme01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bme00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BMEI0575
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BMEI0575
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BMEI0575
Enzymes [BR:
bme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BMEI0575
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AAL51756
UniProt:
Q8YI70
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All DBs
Position
I:593644..595089
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AA seq
481 aa
AA seq
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MSNRELSDWLWTSDAMVEAMEGRPFGNLPAGVTGISIDSRTLKPGEAFFAIKGEQFDGHD
FATAAMAAGAGLLVVAEHRLPAFGNTKVPMIVVEDVLEALIRLGIAARARSKAQIIAVTG
SVGKTTTKEALRHVLSDVGKVHASAASFNNHWGVPLTLARMPADVDYGVFEIGMNHHGEI
RPLVKMVRPHVALITLIAPAHLGHFANLEEIAVAKAEIFEGIVPGGYALLNRDDKRFRQL
QELAEKAGVEHIATFGENARADYRLRDVKLHPTCSCMTVKIGTHEAAVKVGIPGRHVVQN
MLAVLGAAHLVGADIAKVMMAMATLSAQGGRGARHVLQHPEGAFTLIDESYNANPTSMRA
ALSLLHSTVPEGSRGRRIAVLGDMVELGRQSGKLHADLARPIVDAEVNTLFIGGSEMSVL
KNALPVEIQTEYRQSTDELLPLVVKAVRPGDVVMVKSSNRTGFSKIVKALIAQFPPVEAA
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgagcaatcgggaattgagcgattggctctggacatccgacgccatggtggaagccatg
gaaggcaggccgttcggcaatctgccggcgggagtaaccggcatttccatcgatagccgc
accctgaagcccggtgaggcttttttcgccatcaagggcgaacagttcgacggccacgat
tttgcaacggccgccatggcggcaggcgcggggcttctggttgtggcggaacatcgcctg
cctgctttcggcaatacaaaagtgccgatgatcgtggtcgaggacgtgctggaagccctg
atcaggcttggcatcgctgcgcgcgcgcgctcgaaggcgcagatcatcgccgtgacgggt
tcggtcggcaagacaaccaccaaggaagccctgcgccatgttctgtccgatgtcggcaag
gttcatgcttccgccgcctcgttcaacaatcattggggcgtgccgctgacacttgcccgt
atgcccgccgatgtggattacggcgtgttcgagatcggcatgaaccatcatggcgaaatc
cgtccgctggtgaagatggtgcgcccgcatgtcgcgctgattacgctgattgcaccggcg
catcttggccattttgccaatctggaagagattgcggttgccaaggcggagattttcgag
ggcatcgtgcctggtggctatgcgcttttgaaccgcgacgacaagcgcttcaggcaattg
caggaactggccgaaaaggccggggtcgaacatattgcgactttcggcgagaatgcgcgt
gccgattatcgcctgcgcgatgtgaagcttcatccaacctgttcgtgcatgacggtgaag
atcggaacgcatgaggcagcggtgaaggtgggaataccgggccgccatgtcgtgcagaac
atgcttgccgttctcggcgccgcgcaccttgtcggtgcggatattgccaaggttatgatg
gcgatggcgacgctttctgcccagggcgggcgcggtgcacgtcatgtgcttcaacatccg
gaaggcgctttcacgctgatcgatgaaagctacaatgccaatccgacctcgatgcgcgcg
gccctttcgctgctgcattcgaccgtaccggaaggatcgcgcgggcggcgtattgcggtt
ctgggcgatatggtggaacttggccgacagtccggcaagctgcatgcagaccttgcgcgt
cccattgtggacgcggaagtgaatacactttttatcggcggatcggagatgtctgtgctg
aaaaatgccttgccggttgaaattcagaccgaatacaggcagagcaccgacgaattattg
ccgcttgtggtcaaggcggtccgtcccggcgatgtcgtcatggtgaaatcgtccaacagg
accggcttctccaaaatcgtcaaggcgctgattgcccagtttccgcccgtagaagcggcg
gaatag
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