Brucella melitensis bv. 1 16M: BMEI1270
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Entry
BMEI1270 CDS
T00072
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bme
Brucella melitensis bv. 1 16M
Pathway
bme00290
Valine, leucine and isoleucine biosynthesis
bme00620
Pyruvate metabolism
bme01100
Metabolic pathways
bme01110
Biosynthesis of secondary metabolites
bme01210
2-Oxocarboxylic acid metabolism
bme01230
Biosynthesis of amino acids
Module
bme_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bme00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BMEI1270
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BMEI1270
Enzymes [BR:
bme01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BMEI1270
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AAL52451
UniProt:
Q8YG91
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All DBs
Position
I:complement(1321139..1322770)
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AA seq
543 aa
AA seq
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MPGRAIMARERIYIYDTTLRDGQQTPGVDFSVEDKKSIVTLLEELGVDYVEGGYPGANPT
DTAFFKRRQTARAKFVAFGMTKRAGVSVSNDPGLSSLLQASADAVCFVAKSWDYHVRLAL
GCTNEENLESITASVTAARMAGREALVDCEHFFDGYKANPEYALACAKAAYSAGARWVVL
CDTNGGTQPLEVAAIVEAVKAVVPGESLGIHAHNDTEQAVAVSLAAIDAGVRHVQGTLNG
IGERCGNANLVSLIPTLVLKPYWAERFELGIKPASLKSITRISRAFDDILNRPATEQAPY
TGTSAFATKAGIHASALMKEPQTYEHIPPESVGNSRRVMVSDQGGKSNFIAELERRGIRV
AKDDVRLDTLIALVKEREAEGYAYEGADASFELLARGMLNPQPEFFKVESFRCLVERRFD
ANGMLKTVSEAVVKVEVDGEMHMSVAEGHGPVNALDIALRKDLGRFQAEIEDLELVDFKV
RILNGGTAAITRVLIESGDATGARWRTVGVSDNIIDASFQALMDSVNYKLMKNRAMAGLA
AAE
NT seq
1632 nt
NT seq
+upstream
nt +downstream
nt
ttgcctgggagggcaataatggcacgcgagcgcatttatatttacgatacgaccctgcgg
gatgggcagcaaacgcccggcgttgacttctctgtggaggacaaaaagtcgattgtcacg
ctgttggaagagctgggcgtcgattatgtggaaggcggttatccgggggccaacccgact
gatacggctttcttcaagcgtcgccagaccgctcgcgccaagttcgtggctttcgggatg
acaaagcgggcgggcgtttccgtttccaacgatcccggcctgtcgagcttgttgcaggct
tctgccgatgcggtctgctttgtcgccaagagctgggattatcatgtgcgtctggcgctc
ggctgcaccaatgaggaaaatctggaatccatcacggcttcggtaacggcggcgcgcatg
gctggccgtgaggcgctggtcgattgcgaacatttcttcgatggatacaaggcgaacccg
gaatatgcgctggcctgcgcgaaggcggcctattcggcgggtgcgcgctgggtggtgctg
tgcgataccaacggcggcacgcagcctctggaagtggcggcaatcgttgaagcggtgaag
gcggttgttcccggtgagagcctcgggatccatgcccataacgataccgaacaggctgtt
gcggtttcccttgctgcaatcgatgcgggggtgcgtcatgtgcagggcaccttgaacggc
attggcgagcgttgcggcaatgccaatctcgtttcactcatcccgacgctggttctcaaa
ccatattgggcggagcggttcgagcttggcatcaagcctgcatcgctgaaatccatcacg
cgcatttcgcgcgctttcgatgatatcctgaaccgcccggccacggagcaggcaccctat
acgggcacttcggcctttgccacgaaggctggcatccacgcttcggcgctgatgaaagag
ccgcagacctacgagcatattccgccggaatcggttggcaatagccgccgtgtcatggtg
tcggatcagggcggcaagtcgaatttcattgccgagctggagcgccggggtatccgcgtt
gccaaggacgatgttcggctcgatacgctgattgcgctggtcaaggagcgtgaggccgag
ggttatgcctatgagggtgcggacgcaagttttgagcttctggcacgcggtatgctcaat
ccgcaaccggagttcttcaaggttgaatcgttccgctgcctcgtggagcgccggtttgat
gccaacggcatgttgaaaaccgtgtccgaggcggtggtcaaggtcgaggtggatggcgag
atgcatatgtcggtcgcggagggccatggccctgtcaacgcgctcgatatcgcattgcgc
aaggatctgggccgctttcaggccgagatcgaggatctcgaactggtcgatttcaaggtg
cgtattctcaacggcggcacggcggcgatcacccgcgttctgatcgaatcgggtgatgcc
acgggtgcgcgctggcgcacggtgggcgtttccgacaatatcatcgatgcttcctttcag
gctttgatggattccgtcaattacaagctgatgaaaaaccgggccatggcaggtctggcc
gctgccgaatag
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