KEGG   Brucella melitensis bv. 1 16M: BMEI1270
Entry
BMEI1270          CDS       T00072                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
bme  Brucella melitensis bv. 1 16M
Pathway
bme00290  Valine, leucine and isoleucine biosynthesis
bme00620  Pyruvate metabolism
bme01100  Metabolic pathways
bme01110  Biosynthesis of secondary metabolites
bme01210  2-Oxocarboxylic acid metabolism
bme01230  Biosynthesis of amino acids
Module
bme_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:bme00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    BMEI1270
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    BMEI1270
Enzymes [BR:bme01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     BMEI1270
SSDB
Motif
Pfam: HMGL-like LeuA_dimer HCS_D2
Other DBs
NCBI-ProteinID: AAL52451
UniProt: Q8YG91
LinkDB
Position
I:complement(1321139..1322770)
AA seq 543 aa
MPGRAIMARERIYIYDTTLRDGQQTPGVDFSVEDKKSIVTLLEELGVDYVEGGYPGANPT
DTAFFKRRQTARAKFVAFGMTKRAGVSVSNDPGLSSLLQASADAVCFVAKSWDYHVRLAL
GCTNEENLESITASVTAARMAGREALVDCEHFFDGYKANPEYALACAKAAYSAGARWVVL
CDTNGGTQPLEVAAIVEAVKAVVPGESLGIHAHNDTEQAVAVSLAAIDAGVRHVQGTLNG
IGERCGNANLVSLIPTLVLKPYWAERFELGIKPASLKSITRISRAFDDILNRPATEQAPY
TGTSAFATKAGIHASALMKEPQTYEHIPPESVGNSRRVMVSDQGGKSNFIAELERRGIRV
AKDDVRLDTLIALVKEREAEGYAYEGADASFELLARGMLNPQPEFFKVESFRCLVERRFD
ANGMLKTVSEAVVKVEVDGEMHMSVAEGHGPVNALDIALRKDLGRFQAEIEDLELVDFKV
RILNGGTAAITRVLIESGDATGARWRTVGVSDNIIDASFQALMDSVNYKLMKNRAMAGLA
AAE
NT seq 1632 nt   +upstreamnt  +downstreamnt
ttgcctgggagggcaataatggcacgcgagcgcatttatatttacgatacgaccctgcgg
gatgggcagcaaacgcccggcgttgacttctctgtggaggacaaaaagtcgattgtcacg
ctgttggaagagctgggcgtcgattatgtggaaggcggttatccgggggccaacccgact
gatacggctttcttcaagcgtcgccagaccgctcgcgccaagttcgtggctttcgggatg
acaaagcgggcgggcgtttccgtttccaacgatcccggcctgtcgagcttgttgcaggct
tctgccgatgcggtctgctttgtcgccaagagctgggattatcatgtgcgtctggcgctc
ggctgcaccaatgaggaaaatctggaatccatcacggcttcggtaacggcggcgcgcatg
gctggccgtgaggcgctggtcgattgcgaacatttcttcgatggatacaaggcgaacccg
gaatatgcgctggcctgcgcgaaggcggcctattcggcgggtgcgcgctgggtggtgctg
tgcgataccaacggcggcacgcagcctctggaagtggcggcaatcgttgaagcggtgaag
gcggttgttcccggtgagagcctcgggatccatgcccataacgataccgaacaggctgtt
gcggtttcccttgctgcaatcgatgcgggggtgcgtcatgtgcagggcaccttgaacggc
attggcgagcgttgcggcaatgccaatctcgtttcactcatcccgacgctggttctcaaa
ccatattgggcggagcggttcgagcttggcatcaagcctgcatcgctgaaatccatcacg
cgcatttcgcgcgctttcgatgatatcctgaaccgcccggccacggagcaggcaccctat
acgggcacttcggcctttgccacgaaggctggcatccacgcttcggcgctgatgaaagag
ccgcagacctacgagcatattccgccggaatcggttggcaatagccgccgtgtcatggtg
tcggatcagggcggcaagtcgaatttcattgccgagctggagcgccggggtatccgcgtt
gccaaggacgatgttcggctcgatacgctgattgcgctggtcaaggagcgtgaggccgag
ggttatgcctatgagggtgcggacgcaagttttgagcttctggcacgcggtatgctcaat
ccgcaaccggagttcttcaaggttgaatcgttccgctgcctcgtggagcgccggtttgat
gccaacggcatgttgaaaaccgtgtccgaggcggtggtcaaggtcgaggtggatggcgag
atgcatatgtcggtcgcggagggccatggccctgtcaacgcgctcgatatcgcattgcgc
aaggatctgggccgctttcaggccgagatcgaggatctcgaactggtcgatttcaaggtg
cgtattctcaacggcggcacggcggcgatcacccgcgttctgatcgaatcgggtgatgcc
acgggtgcgcgctggcgcacggtgggcgtttccgacaatatcatcgatgcttcctttcag
gctttgatggattccgtcaattacaagctgatgaaaaaccgggccatggcaggtctggcc
gctgccgaatag

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