Brucella melitensis bv. 1 16M: BMEII0748
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Entry
BMEII0748 CDS
T00072
Name
(GenBank) 2-oxoisovalerate dehydrogenase alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bme
Brucella melitensis bv. 1 16M
Pathway
bme00280
Valine, leucine and isoleucine degradation
bme00640
Propanoate metabolism
bme00785
Lipoic acid metabolism
bme01100
Metabolic pathways
bme01110
Biosynthesis of secondary metabolites
bme01210
2-Oxocarboxylic acid metabolism
Module
bme_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bme00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BMEII0748
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BMEII0748
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BMEII0748
Enzymes [BR:
bme01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BMEII0748
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AAL53990
UniProt:
Q8YBY8
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Position
II:complement(786825..788057)
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AA seq
410 aa
AA seq
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MSDDVVLSLHVPEPEWRPGDAPDFSHVKIPRAGSVRRPEIDEKPEAMRDMAFSIIRVLNR
EGEAVGPWAGTLTDEELKDGLRHMMMLRAYDARMMMAQRQGKTSFYMQHLGEEAVSCAFR
KALRKGDMNFPTYRQAGLLIADDYPLVTMMNQIFSNEQDPLKGRQLPVMYSSKEHGFFTI
SGNLATQYTQAVGWAMASAISHDTKIAAAWIGDGSTAESDFHAALVFASTYKAPVVMNIV
NNQWAISTFQGIARGGSGTFAARGHGFGIPSLRVDGNDYLAVHAVAKWAVERARRNLGPT
IVEYVTYRAGGHSTSDDPSAYRPKAENDAWPLGDPILRLKNHLIKRGVWSEERHKQAEAE
VMDIVVSAQREAEAIGTLHDGRKPSMRDMFEDVYAETPPHLIRQRQEAGF
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgatgtcgtactttcactgcatgttcccgagccggaatggcgcccgggtgat
gcgccggatttctcccacgtcaagattccccgtgcaggcagcgtgcgcaggcccgaaatc
gatgaaaagccggaagccatgcgcgatatggcgttcagcatcatccgcgtgctgaaccgg
gaaggtgaggcggttggcccatgggcgggcacgcttaccgacgaggaactgaaggacggg
cttcgtcacatgatgatgttgcgtgcctatgatgcgcgcatgatgatggcgcaacgtcag
ggcaaaacctcgttctacatgcagcatctgggtgaagaggcggtgagttgcgccttccgc
aaggcgctgcgcaagggcgacatgaatttcccgacctaccgccaggcgggccttctcatc
gcggacgactatcccctcgtcacgatgatgaaccagatattctccaacgagcaggacccg
ctgaaaggccgccagcttccggtgatgtattcctcgaaagagcatggctttttcaccatt
tccggcaatctggcgacgcaatatacgcaggccgtcggctgggcgatggcatcggccatc
agccacgacacgaagattgccgccgcatggatcggtgacggctcgacggcggaaagcgat
ttccacgccgcactggtcttcgcctcgacctacaaggccccggtggtgatgaacatcgtc
aacaaccaatgggctatttccacctttcagggcattgcgcgcggcggttccggcactttt
gcggcgcggggccacggcttcggcattccgtcgctgcgcgtcgatggcaatgactatctg
gccgtccatgcggtggcgaaatgggcggtcgaacgcgcgcggcgcaatctcggcccgacc
atcgtggaatatgtgacctatcgcgccggcgggcactccacttcggacgatccgtccgcc
tatcgccccaaggcggaaaatgacgcatggccgcttggcgatccgatcctgcggctcaag
aaccacctcattaagcgcggcgtgtggtcggaagagcgccacaagcaggcggaagccgag
gtgatggatattgtggtgagtgcgcagcgcgaggcggaagccatcggcacgctgcatgat
ggccgtaagccctccatgcgcgacatgttcgaggatgtctatgccgaaacgccgccgcat
cttatccgccagcgtcaggaggcggggttttga
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