Brevundimonas mediterranea: GYM46_07205
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Entry
GYM46_07205 CDS
T06564
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bmed
Brevundimonas mediterranea
Pathway
bmed00280
Valine, leucine and isoleucine degradation
bmed00640
Propanoate metabolism
bmed00785
Lipoic acid metabolism
bmed01100
Metabolic pathways
bmed01110
Biosynthesis of secondary metabolites
bmed01210
2-Oxocarboxylic acid metabolism
Module
bmed_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bmed00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
GYM46_07205
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
GYM46_07205
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GYM46_07205
Enzymes [BR:
bmed01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
GYM46_07205
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QIH72754
UniProt:
A0AB37E654
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Position
complement(1479474..1480733)
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AA seq
419 aa
AA seq
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MDARMNDKLSQKNSRPLSLRVPEPSGRPGDAPDFSHLLMDAPGAVERPEVGTTPYEMRDL
AFRLIRVLDDEGQAVGPWNPRLDPDTLRRGLKAMILTRAFDDRMHRAHRQGKTSFYMKCT
GEEAIAVAQGMLLSREDMGFPTYRQQGLLIARGYPLVEMMNQIYSNAADPIKGRQLPIMY
SAKDYGFFTISGNLGTQVPQAVGWAMASAYKGDDKIAISWIGDGATAEGDFHNALTFASV
YRAPVILNIVNNQWAISSFQGIAGGLETTFASKAIGYGLPALRVDGNDFLAVWAATQWAE
ERARSNQGATVIELFTYRGAPHSTSDDPSRYRPGDEHEKWPLGDPLERLRQHLTVIGEWD
DERHAVALREAVEQVRAAGKESEAIGTLGQSRPSVKTMFEEVYATEDWRLIEQRREVGV
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atggacgcccgcatgaacgacaaattgagccaaaagaacagccgcccgctgtcgctgcgc
gtgcccgagccttcgggccggccgggcgacgcgcctgacttcagtcatctgttgatggac
gcccccggcgccgtcgaacggcccgaggtgggcacgacgccttacgagatgcgcgacctt
gcgttccggttgatccgggtgctggacgacgaaggccaggccgtcggtccgtggaatccg
cgtctggatccggacaccctgcgtcgcggcctgaaggccatgatcctgacccgcgccttc
gacgaccggatgcaccgcgcccaccgccagggcaagaccagcttctacatgaaatgcacc
ggcgaggaggccatcgcggtcgcgcaaggcatgctgctgagccgcgaggacatgggtttt
ccgacctaccgccagcaggggctgctgatcgcccgcggctatccgctggtcgagatgatg
aaccagatctattccaatgctgcggacccgatcaaagggcgtcagctgccgatcatgtat
tcggccaaggactacggcttcttcaccatcagcggcaatctgggcacccaggtgccccag
gccgtgggctgggccatggccagcgcctacaagggcgacgacaagatcgccatcagctgg
atcggcgacggcgccacggccgagggcgattttcacaacgccctgaccttcgcctccgtc
tatcgcgcgccggtcattctgaacatcgtcaacaaccagtgggccatcagctccttccag
ggcatcgccggcgggctggagaccaccttcgcctccaaggccatcggctatggcctgccg
gccctgcgggtggacggcaacgacttcctggcggtctgggcggcgacccagtgggccgag
gagcgcgcccggtccaaccagggggcgacggtgatcgaactgttcacctatcgcggcgcc
ccgcactcgacctccgacgaccccagccgctaccgccccggcgacgagcacgagaaatgg
ccgctgggcgatccgctggagcggctgcgccagcacctgaccgtcatcggcgagtgggat
gacgagcgccacgccgtcgccctgcgcgaggcggtcgaacaggtccgcgccgccggcaag
gaatcggaggccatcggcaccctgggccagtcgcgccccagcgtgaagacgatgttcgaa
gaggtctatgcgaccgaagactggcggctgatcgaacagcgccgcgaggtgggggtctga
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