Bacillus megaterium NBRC 15308 = ATCC 14581: BG04_1686
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Entry
BG04_1686 CDS
T03825
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
bmeg
Bacillus megaterium NBRC 15308 = ATCC 14581
Pathway
bmeg00290
Valine, leucine and isoleucine biosynthesis
bmeg00660
C5-Branched dibasic acid metabolism
bmeg01100
Metabolic pathways
bmeg01110
Biosynthesis of secondary metabolites
bmeg01210
2-Oxocarboxylic acid metabolism
bmeg01230
Biosynthesis of amino acids
Module
bmeg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bmeg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
BG04_1686 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BG04_1686 (leuC)
Enzymes [BR:
bmeg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
BG04_1686 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
BG04_1686 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AJI25147
UniProt:
A0A0B6AVJ1
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Position
complement(1541793..1543208)
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AA seq
471 aa
AA seq
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MKPKTIIDKLWEQHVVRREEGKPDLLYIDLHLIHEVTSPQAFEGLRVANRQVKRPDLTFA
TMDHNIPTVDRFNIKDPIAKKQVDKLSENCHEFGVKLLDLTSEEQGIVHIIGPELGLTQP
GKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLWQAKPKTLQVKVNGKKQPGVYA
KDIVLAIIQKFGVNFGTGSIVEFTGECIRDLSMEERMTICNMSIEAGAKAGLISPDDVTF
SYIKGRQYAPKGEQFEKAVEAWAALATDEGATYDETLEIDADTIEPVVTWGTNPAMSSYV
SKQVPTLEECKTEAERKSLSRALEYMGLQPGMAIEEIPVQHVFIGSCTNARLSDLRDVAA
FIKGKKVSPDVRAIIVPGSQKVKRVAEEEGLSAIFIEAGFDWRDSGCSMCLGMNSDLVPQ
GEHCASTSNRNFEGRQGKGARTHLVSPVMAAAAAVYGHFVDVRKLQEQAVR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccaaaaacaattattgataagctttgggaacaacatgttgtacgtcgagaagag
gggaagccggacttattatatatcgatcttcatcttattcatgaagtaacgtctcctcaa
gcatttgaaggtcttcgcgtggcaaatcgccaagtgaagcgtccagacttaacgtttgct
acaatggatcacaacattccaacagttgaccgttttaatattaaagatccgattgcaaag
aaacaagtagacaaactatctgaaaactgtcatgagtttggtgtgaagcttttagattta
acaagtgaagagcaaggaattgtgcatatcattggaccggaattaggattaactcagcct
ggaaaaaccattgtgtgcggagatagtcatacatctactcacggtgcatttggagcgctt
gcttttgggataggaactagtgaggtagagcatgttttagcaacacaaacgctatggcaa
gcgaaaccaaaaacgctacaagtgaaagtgaatggcaaaaagcagcctggcgtttatgct
aaggacattgtgttagcaataattcaaaaattcggtgtgaattttggaacgggttcaatc
gtggaatttacgggcgaatgtattcgcgatctttcaatggaagagcgcatgaccatttgt
aatatgtctattgaagccggtgcaaaagctggtttaatcagtccagacgatgtcacgttc
tcttatattaaaggacgtcagtatgctcctaaaggagaacagtttgaaaaagcagtggaa
gcttgggcagctttagcaacagatgaaggtgcaacgtacgatgaaacgctggaaattgat
gcagatacaattgaacctgttgtaacatggggaacaaacccggcgatgagttcttatgtt
agcaagcaagttcctacattagaagagtgtaaaacagaagctgagagaaagtctttgtca
cgagcacttgagtatatgggcttacagcctggtatggcaatagaagagattccagttcag
catgtatttatcggttcatgtacgaatgctcgtttgtctgatcttcgtgacgtggcagcc
tttattaaaggaaagaaagtgtcaccagatgtgcgagcgatcattgtaccaggttctcaa
aaagtaaagcgagtggctgaagaagaagggttatctgctatttttattgaagcaggtttt
gattggagagactcaggctgcagcatgtgtctaggcatgaactctgacttagttccacaa
ggcgaacactgtgcgtccacttctaaccggaattttgaaggacgtcaaggaaaaggcgcc
agaacgcatttagtaagcccggtaatggcagcagcggcagcggtatatggacattttgtt
gatgtacgcaaactacaagaacaagcggtgcgataa
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