Brucella melitensis bv. 1 16M: DK63_972
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Entry
DK63_972 CDS
T03831
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bmel
Brucella melitensis bv. 1 16M
Pathway
bmel00290
Valine, leucine and isoleucine biosynthesis
bmel00620
Pyruvate metabolism
bmel01100
Metabolic pathways
bmel01110
Biosynthesis of secondary metabolites
bmel01210
2-Oxocarboxylic acid metabolism
bmel01230
Biosynthesis of amino acids
Module
bmel_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bmel00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DK63_972 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DK63_972 (leuA)
Enzymes [BR:
bmel01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DK63_972 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AIJ89051
UniProt:
Q8YIJ3
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All DBs
Position
1:complement(985811..987478)
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AA seq
555 aa
AA seq
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MPIAGTKYAPFPAPQLDDRTWPSKRIEKAPIWCSVDLRDGNQALIDPMGHDRKERMFRLL
IDMGFPEIEIGFPSASQTDFDFCRWAIEQGDVPDDVDLQVLVQCRPELITRTFEALEGAK
TPIIHFYNSTSELQRRVVFAKDVGGIKQIATDAAKMIMDMAAKAGGGYRFQYSPESFTGT
ELDVALEICNAVIEIVKPTPDNKLIVNLPSTVEMNTPNVYADQIEWMCRNLDNRESLIIS
LHPHNDRGTGIAATELGLMAGADRGEGTLFGNGERTGNVDVVTLALNMYTQGIDPGLDCT
DINRMKEVYEYSNQLKIAERHPYVGELVYTAFSGSHQDAINKGMKARRSANSPVWEVPYL
PIDPQDVGRSYEAIIRINSQSGKGGIAYILQADYGLNLPRNLQVEFREIIQHITDEEGKE
LPSKRIYEEFQKLYVTQPDARIKFVDHHTYPHPEQKGRRILTAEITDNGVTKTIEGKGTG
PIDGFVDALSKYLGVKMSVVDYSEHSLQQGSDASAISYVEMVYPGGKLFGVGINDNIVSA
SLEAVVSAANRVIAK
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atgcctattgccggtaccaaatacgcgccgttccctgcgccgcagctcgatgaccgcact
tggccttccaaacgcatcgaaaaggcgccgatctggtgttcggtcgatctgcgcgacggc
aaccaggctttgatcgaccccatggggcatgaccgcaaggagcgcatgttccgcctgctg
atcgatatgggtttcccggaaatcgagatcggtttcccgtccgcttcgcagacggatttc
gacttctgccgctgggccattgaacagggcgatgttcctgacgacgtggatttgcaggtt
ctggtccagtgccgtcctgaattgattacgcgcactttcgaggcgctggaaggcgcgaag
acgccgatcatccatttctacaattccaccagcgaattgcagcgccgcgtggtgtttgcc
aaggatgtcggcggcatcaagcagattgcaaccgatgcggccaagatgatcatggatatg
gctgccaaggctggcggcggttatcgcttccagtattcgccggaaagctttaccggcacc
gaactggatgtggcgctggaaatctgcaatgcggtgatcgagatcgtgaagccgacgccg
gacaacaagctgatcgtcaacctgccttcgacggtggagatgaacacgccgaatgtctat
gccgaccagatcgaatggatgtgccgcaatctggacaatcgcgagagcctgattatctcg
ctgcatccgcataatgaccgcggcacgggcattgccgccactgaactgggcctgatggca
ggcgctgatcgcggggaaggcacgctgttcggcaatggcgagcgcacgggcaatgtggat
gtggtgacgctggcgctcaacatgtacacgcagggcatcgaccccgggctggattgcacc
gatatcaaccggatgaaggaagtctacgaatattccaaccagttgaagatcgccgagcgc
catccttatgtgggcgagctggtctatacggctttctccggctcgcatcaggatgcgatc
aacaagggcatgaaagcgcgccgttcggccaattcgccggtttgggaagttccttacctg
ccgatcgatccgcaggatgtgggccgctcctacgaggcgatcatccgcatcaattcgcaa
tcgggcaagggcggtatcgcctatatcctgcaagccgattacggcctgaacctgccgcgc
aacctgcaggtcgagttccgcgaaatcatccagcacattacggatgaagagggcaaggag
ctgccatcgaagcgcatttacgaggagttccagaaactctatgtgacgcagcccgatgcc
cgcatcaagttcgtggatcaccacacctatccccatcctgagcaaaagggccggcgcatc
ctgacggctgagatcaccgataacggtgtcaccaagactatcgagggcaagggcacggga
ccgatcgatggtttcgtggatgcgctgtcgaaatatcttggcgtgaaaatgtcggtggtc
gattattccgaacattcgctccagcagggttcggatgcttcggccatttcctatgtcgag
atggtttatcccggcggcaagctgttcggtgtcggcatcaacgataatatcgtcagcgcc
tcgcttgaagccgtggtgtcggcggcaaatcgtgtgattgcgaagtag
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