Brucella melitensis ATCC 23457: BMEA_A1961
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Entry
BMEA_A1961 CDS
T00867
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
bmi
Brucella melitensis ATCC 23457
Pathway
bmi00290
Valine, leucine and isoleucine biosynthesis
bmi00660
C5-Branched dibasic acid metabolism
bmi01100
Metabolic pathways
bmi01110
Biosynthesis of secondary metabolites
bmi01210
2-Oxocarboxylic acid metabolism
bmi01230
Biosynthesis of amino acids
Module
bmi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
BMEA_A1961 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BMEA_A1961 (leuC)
Enzymes [BR:
bmi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
BMEA_A1961 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
BMEA_A1961 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
DUF3717
Motif
Other DBs
NCBI-ProteinID:
ACO01623
UniProt:
C0RFF1
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All DBs
Position
I:complement(1858649..1860058)
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AA seq
469 aa
AA seq
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MSAPRTLYDKIWDDHVVDQQEDGTCLLYIDRHLVHEVTSPQAFEGLHMAGRPVRHPEKTL
AVVDHNVPTSPDRINGIQNEESRIQVEALARNAADFGVEYYSERDKRQGIVHIVGPEQGF
TLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGKLPAG
VTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAPDE
TTFEYIKGRPRAPQGETLEQAINYWKTLHSDEGAHFDKIVTLDAGSLPPIVSWGSSPEDV
VSVTGVVPNPDDIADETKRASKWRALDYMGLKPGTKITDIAVDRVFIGSCTNGRIEDLRA
AAKVVEGKKVAPTVNAMIVPGSGLVKEQAEAEGLHKIFIEAGFDWREPGCSMCLAMNDDR
LKPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIRAWK
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcgccgcgtacactttatgacaagatttgggatgaccatgtagtggatcagcag
gaagacggcacctgcctcctttatattgatcgccatcttgtgcatgaagtgacgagcccg
caggcctttgaggggctgcacatggcaggccgcccggtgcgccacccggaaaagacgctt
gccgtggtggaccataacgttccgacgtcgcccgaccgcatcaatggcatccagaacgag
gaaagccgcatccaggtcgaggcactggccaggaatgccgccgatttcggcgtcgaatat
tattccgaacgcgacaagcgccagggcatcgtgcatatcgtcgggccagagcagggcttc
accctgccgggcatgaccatcgtttgcggtgacagccacacttccacccacggcgctttc
ggtgcgcttgcacatggcatcggcacatcggaggtggagcatgtgctcgccacccagacg
ctgatccagaaaaaagccaagaatatgctggtgcgcgttgacggcaagttgccggcgggc
gtgaccgccaaggatattgttctggcgatcattggcgagatcggcacggcaggcggcacc
ggctatgtcatcgaatatgcgggcgaagccattcgctcgctgtcgatggaaggccgcatg
acgatctgcaacatgtcgatcgagggcggcgcgcgtgccggtcttatcgctcccgacgag
acgacgtttgaatatatcaagggccgcccgcgtgctccgcagggcgaaacgctggaacag
gcgatcaattactggaagacgctgcattcggatgaaggggcgcatttcgacaagatcgtg
acgctcgacgccggcagcctgccgcccatcgtttcctggggttcttcgccggaagacgtc
gtttccgtcacgggggtcgtgcccaatccggacgatatcgccgacgaaaccaagcgtgcc
tccaagtggcgtgcgctcgactatatgggcctgaagcccggcacgaaaatcacggatatc
gcggttgatcgcgtcttcatcggttcgtgcaccaatggccgcatcgaagaccttcgcgct
gccgccaaggtcgtggaaggcaagaaggttgccccgaccgtcaatgccatgatcgttccg
ggttcgggtctcgtaaaggaacaggcggaagccgaaggcctgcacaagattttcattgaa
gccggtttcgactggcgcgagccgggctgctccatgtgccttgcgatgaacgatgaccgg
ctgaagccgggcgagcgttgcgcttcgacctcgaaccgcaatttcgagggccgtcagggc
ttcaagggtcgtacgcatctggtatcgccagcaatggctgcggcggctgcaattgccggt
cacttcgtcgatattcgcgcgtggaagtga
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