Bombyx mori (domestic silkworm): 101739070 Help Entry 101739070         CDS       T02817                                  Name (RefSeq) ryanodine receptor isoform X7   KO K04962   ryanodine receptor 2 Organism bmor  Bombyx mori (domestic silkworm) Brite KEGG Orthology (KO) [BR:bmor00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:bmor04040]     101739070    04990 Domain-containing proteins not elsewhere classified [BR:bmor04990]     101739070 Ion channels [BR:bmor04040]  Voltage-gated cation channels   Ryanodine receptor    101739070 Domain-containing proteins not elsewhere classified [BR:bmor04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    101739070 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  101739070 NCBI-ProteinID:  XP_012544765 UniProt:  A0A8R2G974 LinkDB All DBs Position 24:complement(3936816..4109362) Genome browser AA seq 5125 aa AA seqDB search MAEAEGGASEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDL SQCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYGNAILLRHLNSDMYLACLST SSSQDKLAFDVGLQEHSQGEACWWTLHPASKQRSEGEKVRVGDDLILVSVATERYLHTTK ENEVSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWTRDG GQNIVVYEGGSVMSQARSLWRLELARTKWAGGFINWYHPMRIRHITTGRYLGVNDQNELH LVSREEATTASCAFCLRQEKDDQKQVLEDKDLEVIGAPIIKYGDSTVIVQHSETGLWLSY KSYETKKKGVGKVEEKQAILHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTKFINGL ETLQENRRHSMFFASVNLGEMVMCLEDLINYFAQPDEDMEHEEKQNKFRALRNRQDLFQE EGILNLILEAIDKINVITSQGFLAGFLAGDESGQSWEMISGYLYQLLAAIIKGNHTNCAQ FANSNRLNWLFSRLGSQASGEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGR DPKVLDVLCSLCVGNGVAVRSSQNNICDYLLPGKNLLLQTQLVDHVSSVRPNIFVGRVEG SAVYRKWYFEVTMDHIEKTTHMMPHLRIGWANTSGYVPYPGGGEKWGGNGVGDDLYSFGF DGAYLWSGGRKTPVNRTHHEEPYIRKGDVIGCALDLNVPLINFMFNGVRVTGSFTNFNLE GMFFPAISCSSKLSCRFLFGGEHGRLRYAAPEGYSPLVESLLPQQILSLEPCFYFGNLNK RALAGPSLVQDDTAFVPTPVDTMTISLPTYVEQIRDKLAENIHEMWAMNKIEAGWMYGDQ RDDIHKIHPCLVPFERLPPAEKRYDIQLAVQTLKTILALGYYITLDKPPARIRNVRLPNE PFLQSNGYKPAPLDLGAVTLTPKMDELVDQLAENTHNLWARERIQQGWTYGLNEDPEMHR SPHLVPYPKVDDAIKKANRDTASETVRTLLVYGYNLDPPTGEQHEALLAEASKQKQADFR TYRAEKNYAVSSGKWYFEFEILTAGPMRVGWAHADMAPGMMLGQDENSWAFDGYNEEKVY SSSTEAFGKQWAVGDVVGVFLDLIDKTISFSLNGELLMDALGGETTFADVQGDNFVPACT LGVGQKARLTYGQDVNTLKYFTTCGLQEGYEPFCVNMKRDVTHWYTKDQPIYENTDEMAD TRIDVTRIPAGSETPPCLKISHNTFETMEKANWEFLRLSLPVICHSQFIDESEKARRWVE IKERQQILMKEATEAQIPAHIDQIMRSGFTMNDIKGLHYEDNQEEIQSSKVKRQPSRPPR KGSVTRGVTIQNYNTPSGQQVNGIHRSTSEAEMAKYELGAQTLAPDEKKDKRGRSPFKFF KSKRAESSDRAKIRKSKTPDPFSDTELSPDRGTKRPNPQIKVSQPNQRYNNGTQPRASRP NLYGSQSGLNMATPTQERKQLMTTTNLSAAATETVGNEIFDSECLKLINEYFYGVRIFPG QDPTHVYIGWVTTQYHLHSKDFNQNKVMKSSVIITDDYDRVIESVNRQSCYMVRADELYN EVMAEATAKGASQGMFIGCSVDTSTGTVAFTCEGKSTSIKFKMEPETKLFPAIFVEATSK EILQIELGRSPTSLPLSAAVLPTSDKHVTPQFPPRLKVQCLKPHQWARVPNSSLQVHALK LSDIRGWSMLCEDAVSMLALHIPEEDRCIDILELIEMDKLLSFHSHTLTLYAALCYQSNY RAAHALCQHVDQKQLLYAIKSQYMSGPLRQGFYDLLIALHLESHATTMETCKNEFVIPLG PELKVLYDEPDMGHSLRSLQTESVRPQLEMTDITEKSIMDISNLYSPKFPLEVVREFVMQ ALAEAVETNQVHNRDPVGGSNENLFLPLIKLVDRLLLVGKMRDEDVEKLLIMINPETWDP TFNKEGKDEHRKGLLHMKMAEGAKLQMCYLLQHLNDMQLRHRVESIVAFAHDFVGDLQSD QLRRYTEIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKHLEDIDKENCPCGEELIARM NGFHESLMVHVSLNALQEPDPEEPTEPEIKPGAINKLYSLINTVKELEEEPKTLEEPAKK TPEERFRKVLIQTIVNWAEESQIETPKLVREMFSLLVRQYDAVGELIRALEKTYVINAKT KQDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNHTFFQHPDLIRVLRVHENVM AVMMNTLGRRAQAQSDAAPNQPLAEDTKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFD HFDFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQS NSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALR GEGEGLLKAIVDANKMSERIADRRKLREIEQEGDINFSHPLPESDDDEDYIDTGAAILNF YCTLVDLLGRCAPDAAVIALGKNESLRARAILRSLVPLEDLQGVLSLRFTLNNPAAGEER PKSDMPSGLIPGHKQSVGLFLERVYGIETQELFYKLLEEAFLPDLRAATMLDRNDGCESD MALSMNRYIGNSILPLLIKHANFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSD FLVALTSAMQPSMLLKLLRKLTVDVSRLSEYTTVALRLLTLHYERCAKYYGSTGGQGIYG ASSDEEKRLTMMLFSNIFDSLSKMDYEPELFGKALPCLIAIGCALPPDYSLSKNYDDEFY GKEQASVGSDNPQYDPQPINTSSVALNNDLNTIVQKFSEHYHDAWASRKIENGWVYGESW SDSQKTHPRLKPYNMLNDYEKERYKEPVRESLKALLALGWSVEHSDVDLPANSRGSVRRQ SKSGLRSSELPTDSATPFNYNPHPVDMTNLTLSREMQNMAERLADNAHDIWAKKKKEELV TNGGGIHPQLVPYDLLTDKEKKKDRERSQEFLKYLQYQGYKLHRPSKIPQSDTEQTSAGV AIELRFAYSLLEKLIQYIDRATINMKLLKPSTTFSRRSSFKTSTRDIKFFSKVVLPLMEK YFSTHRNYFIAVATATNNVGAASLKEKEMVAALFCKLASLLRSRLAAFGPDVRITVRCLQ VLVKGIDAKSLVKNCPEFIRTSMLTFFNNMADDVGHTIINLQDGKYAHLRGTHLKTSTSL GYINGVQLPVLTAMFDHLANCEYGSDLLLDEIQVASYKMLGSLYTLGTDVTLTHDRKYLK TEIERHKPALGSCLGAFSSTFPVAYLEPHLNKHNQFSLLNRIAEHSLEAQDIMAKMEQSM PTLETILNEVDQFVESDKTYNEAPHIIDVVLPLLCSYLPFWWAQGPDNVTPTGGNHVTMV TAEHMNQLLKNVLKLIKKNIGNESAPWMTRIATYTQQIIINSSEELLRDSFLPLAERVRK RTDNMFHKEESLRGFIKSSTDDTSQVESQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWL RNNVPEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMVLIMPTATRRVTAVVDG TSQSGGKKKKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRFLK KMSEHDVAEFAKTQLTLPDKIDPADEMSWQHYLYSKLGSKSKTAITLENAENKAKIIDDT VERIVAMSKVLFGLHMIDHPQQMSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNI FARTYYELWLEEENIGQEVMIEDLTQSFEDAELKKSDVVEEDGKPDPLTQLVTTFCRGAM TERSGALQEDPLYMSYAHIIAKSCGEEEEEGGGEEEEGGGEAEGEEEGRASIHEQEMEKQ KLLFHQARLANRGVAEMVLLHISASKGVPSEMVMKTLQLGISILRGGNIDIQMGMLNHLK DKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGLEGAAGEKNMHDAEFTCALFRF IQLTCEGHNLDWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDPAG KANFFKAIGVASQVFNTLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHS SQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLK LKDLTSSASFQEIDANNDGWVLPKDFKEKMEQQKSYTPEEIEFLLACCETNHDGKLDYVG FCDRFHEPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEIMGGS KRIERVYFEIKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTH ASGLMAASDDTAGGPKNREASYMYMGDDDDDRAGKDPFRRGIQSVKDGISTAFSSLSPSN IKAKIADLQQMPPAELAVGFFKMFFYMFYYLGYGVLVVVRYIFGVLLGLMRGPQVEEPPP EPTEEEKIGQLRHRLLANQSPRHLPALPPADDTGQMQVSAFGLDITKEDNGQIQVKPHES PTTSTPSSGEEADASLDEGLEHSEEQRPPSLIDLLGGEQAKKQALERIEAQAAQQAAMSA IEAESKKAVQGPASSSALSQVDLSQYTRRAVSFLARNFYNLKYVALVLAFCINFVLLFYK VSTLDGEKAEGSGIGDIIAGSGSGQGSGSGDGSGEEDDALEVVHIDEDFFYMEHVIKVAA VLHSIVSLAILIGYYHLKVPLAIFKREKEIARKLEFDGLYIAEQPEDDDFKSHWDKLVIS AKSFPVNYWDKFVKKKVRAKYSETYDFDSISNMLGMEKTSFSAQEDEGSKGLLHYIINID WRYQVWKAGVTITDNSFLYSLWYFAFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTH NGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYVQEEDDEVNRNCHDMLTCFVFNLYKGVRA GGGIGDELEPPDGDDSEVYRIIFDISFFFFIIVILLAILQGLIIDAFGELRDQLESVKED MESNCFICGINKDYFDKVPHGFDTHVQREHNLANYMFFLMHLINKPDTEYTGQETYVWNM YTQRCWDFFPVGDCFRKQYEDLMGE NT seq 15378 nt NT seq  +upstreamnt  +downstreamnt atggcggaagctgagggcggggcgagcgagcaagatgacgtttccttcttacgaacggaa gacatggtgtgcctctcgtgtaccgctaccggggaacgcgtgtgcctcgcagctgaagga tttggaaaccggcactgcttcctggagaacatcgcggacaagaacataccacccgatctg tcgcaatgcgtcttcgtcatagaacaggcgttatcagtgagagctctccaagaattggtg acggcggccggatcggaaaccggcaagggcactggatccggtcacaggacactgctttac ggaaacgcgatccttttgagacatctcaacagtgatatgtacttggcgtgcttgtcgaca tcatcatctcaagacaaactggctttcgacgttggtctccaagagcactcccagggtgaa gcgtgctggtggacattgcatccggccagtaaacaaagatcggagggtgaaaaagtgcga gtgggagatgatttgattcttgtatctgttgccactgagagatatttgcacacaactaaa gagaatgaagtatcgatcgtcaatgcctcgtttcacgtgacacactggtcggtccagcca tacggaaccggcatctcgaggatgaaatacgtcggctacgtcttcgggggagacgttcta cgtttcttccacggaggagacgaatgccttacaatacctagcacttggactcgggatgga ggacagaatattgtagtatacgaaggcggatcggtcatgtcacaagctcgttcgctatgg cgtttggaactagctcgtaccaaatgggccggaggctttatcaactggtaccatccaatg aggattcggcacatcactacgggtcgatacttgggtgttaacgaccagaatgaactccat ttggtcagcagagaggaagccacaaccgcttcctgcgccttttgtcttcgtcaagaaaaa gatgatcagaaacaagtgcttgaagataaagatttggaagtgatcggagcgccaattatt aaatacggtgactcaacagtaattgtgcagcactctgaaactggcttgtggctttcatat aagtcttacgaaacaaagaagaaaggcgtcggtaaagtagaagagaaacaagccatacta cacgaagaaggtaaaatggacgacggccttgatttctccaggtcccaagaagaagagtcg aggaccgccagagtcatcaggaagtgttcttctttattcactaagttcatcaatggcctt gaaactcttcaagaaaacagaagacactcgatgttcttcgcgtccgtgaacttaggagag atggtgatgtgcttggaggatcttataaactatttcgcacagcccgatgaggacatggaa cacgaagaaaagcaaaacaagttccgtgctcttcgaaaccgccaagatcttttccaagag gagggtatcctgaatttaatcctggaagcaatcgacaagatcaacgtgatcacgtcccag ggattccttgctgggttcctagctggagacgaatcgggacagagctgggaaatgatctct ggatacctttatcagcttttagctgctattataaaaggaaaccacacgaactgcgcacag ttcgcaaactccaaccgtctgaactggttgttctctagactcggctcacaggcatctggc gaaggaactgggatgctggacgtgttgcattgcgtgctcatagactcgcctgaagccttg aatatgatgagggatgagcacataaaagtaatcataagcttattagaaaagcacgggcgt gacccgaaagttctcgacgtgctgtgctcgctgtgcgtcggcaacggagtggccgtgcgc tcgtcccagaacaacatctgcgactacttgctgccagggaagaacttgctactgcagact cagctagtagaccacgtttccagtgtgcgaccgaacattttcgtgggccgcgtcgaagga tcagcagtgtaccgtaaatggtacttcgaagtgacgatggaccacatcgagaaaaccacg cacatgatgccccatctgcgcataggatgggctaacacttctggatacgtaccgtatcct ggtggtggcgaaaagtggggcggtaacggtgtcggtgatgatttgtattcctttggtttc gatggagcatatttgtggtctggtggcaggaaaaccccggttaatcgcactcaccacgaa gaaccttatatcagaaaaggcgatgtgattgggtgcgctctggacttgaacgttccttta atcaacttcatgttcaacggcgtcagggtgaccggatctttcaccaacttcaacttggaa ggcatgttcttccccgccatcagctgctcaagtaaattaagttgtcggtttctattcggc ggcgaacatggtcgtctgcgttacgcggctcccgagggatactctccgctggttgagtcg ctgcttccgcaacagatcctcagtctcgaaccctgcttctattttggcaacctcaacaag agggctctagctggaccatctttagttcaagatgataccgcatttgtgcctacaccggtt gatacgatgacgatatctctgccaacatacgtggaacaaatcagggataagctagccgaa aatattcacgaaatgtgggctatgaataagattgaagccggctggatgtacggtgatcag cgcgacgacatacataagatccatccttgcttggtgcccttcgagcgactaccacctgct gagaagagatacgatatccaactagctgtgcaaacattgaaaacaattcttgcgcttggc tactacattactttggataagccaccagcacgtatccgcaacgtccgacttccaaacgaa ccatttttacagtcaaacggctataaaccagcacctttagaccttggtgctgttactctg acacccaaaatggatgaactagtggaccaattagctgagaatactcacaatctttgggcc agggaaagaatacaacaaggttggacttacggtctcaatgaggatccggagatgcatcgc tcccctcacttagtgccgtatcctaaagttgatgatgccataaaaaaagccaaccgagac accgcgtctgaaactgtccgaactttattggtttacggatataatctggatccgcccact ggagaacagcatgaagctctactagcggaggcttctaagcagaaacaagctgatttcaga acctacagggcggaaaagaactacgccgttagttctgggaaatggtatttcgaatttgaa atattaacggctgggccaatgagggttggttgggctcatgctgacatggctccgggcatg atgttgggacaagacgagaattcttgggcgttcgacggatacaacgaggaaaaggtatac tccagtagcacagaagccttcggcaagcaatgggcagtcggtgatgtggttggcgtgttc cttgatctcatcgataagacgataagtttctctcttaacggagagcttctgatggatgcc cttggcggggagacgacattcgcagatgtccaaggcgataatttcgtgccggcttgcaca cttggggtcgggcagaaggccaggttgacatacggacaagacgtgaacactctaaaatac ttcacgacctgcggtcttcaagagggatacgaacctttctgtgtcaacatgaaaagagat gtcactcattggtacacaaaagaccagcccatctatgaaaacacagatgaaatggccgac acaagaatcgatgtaaccaggataccagctggatcagagactccaccgtgtctgaaaata tctcacaacacattcgaaacgatggaaaaagccaactgggagtttctgcgtttgtctcta ccggtcatttgccattcgcagtttatagatgaatcagagaaagcacgacgctgggtagag attaaggaacgtcagcagatcctcatgaaagaggccaccgaagctcagataccagctcac atcgaccaaatcatgaggagtggatttactatgaatgacataaaaggtctgcactacgaa gacaatcaagaagagatccagagctccaaagtgaaacgtcagccgtccagaccaccacgt aagggttcagtcacacgcggtgtcacgatacagaattacaatacaccatcaggacaacaa gtaaatggaattcatcggtccaccagtgaagcagaaatggcgaaatatgaattaggcgct caaactttagcgccagatgagaagaaagataaaagaggacgttctcctttcaaatttttc aagagcaaacgtgccgagagcagtgatcgcgccaaaatccgcaagtccaaaactccagat cccttcagtgacaccgaactgtctcctgacagggggacgaagagacccaaccctcagatc aaggtgtctcagccgaaccaaaggtataataatggcacgcagccccgagcaagcagaccc aacttgtatggaagtcaaagcggtcttaacatggcgactccaactcaggagagaaagcag ttaatgacaaccacgaatctgtcggccgctgcgacggagaccgtcggcaacgagatattc gactccgagtgcttaaagctcattaatgaatacttctacggggtcagaatattccctggc caagacccaactcacgtgtacattgggtgggtgaccactcagtaccatctgcactcgaaa gacttcaaccaaaacaaggtgatgaagtcatcagtcatcatcaccgacgactacgaccgg gtcattgaaagcgtaaaccgtcagtcctgctacatggtgcgagctgatgagctttacaac gaagtgatggcggaagctacggccaagggcgcgtcccaaggaatgtttattggatgttca gtggacacttccaccgggactgtagcgttcacatgcgagggaaaaagcactagcattaaa ttcaagatggagccagagaccaaattattcccggcgatcttcgtcgaagcgacatcgaaa gagatcctccagatagagctgggcaggtctccgacaagtctaccgctaagtgccgcggtg ctaccaacgagcgacaagcacgtcacgccgcagttcccgcccaggctgaaagtgcagtgt ctcaagccgcatcagtgggctagagtaccaaattcatcgttgcaagtgcacgctctaaag ctgtctgacatacgaggctggtcgatgctgtgcgaagacgcagtttctatgctcgcattg cacataccagaggaagaccggtgcatcgacatattggagcttatcgaaatggataagctg ttgagcttccactcgcacaccctcacgttatatgcagctttatgctaccaaagcaactac agggctgcccacgctttatgccagcatgtagatcaaaagcaattgttatacgccatcaag tcccagtacatgtccgggccactgcgccagggtttctacgatctactcattgctctacat ttagaatcgcacgcaaccacgatggaaacctgcaagaatgaatttgtgatacccctgggg ccggagctgaaggttctgtacgacgagcccgacatggggcacagcctccgctcgctgcag acggagagcgtcagaccgcagttggaaatgaccgatatcacggaaaaaagtataatggac ataagtaatctgtactctccgaagttccctctggaagttgtccgtgaattcgtgatgcag gcactcgcggaggccgtggaaactaaccaggtccacaacagagatccggtcggtggaagc aacgagaatctcttcctgccgctaattaagctcgtggaccgtctactcctggtcggaaaa atgcgcgacgaagacgttgagaaacttctcatcatgatcaaccccgagacctgggatcca acgttcaataaagaaggcaaagacgaacaccgaaaaggacttcttcacatgaaaatggct gaaggcgctaaactgcaaatgtgttatttgctccaacatctgaacgacatgcagctacgt cacagggttgaatctatagtggcttttgcacatgactttgtcggggacctgcagtccgac cagttgagacgctacactgagatcaagcagtcagatttaccgagtgcggttgcagccaag aagaccagagaattccgttgtcctcctagggaacagatgaacgcaatcctgagtttcaaa catcttgaagatatcgataaggagaactgtccttgtggcgaagaactcatcgctaggatg aacggcttccacgaaagtctcatggtccacgtatctctaaacgccctgcaagaacctgat cctgaggagcccactgaaccagaaataaagccgggggccattaataaattatatagcctt ataaataccgtcaaggaactagaagaggaacccaagacattagaggaaccagccaagaag actccggaggaacgtttccggaaagtactcatacagacgatcgtgaattgggcggaggaa tcgcagattgagactcccaagttagtcagggagatgtttagcctactggttcgccagtat gacgccgtaggagaactgatccgagctctcgaaaagacttacgtcatcaatgcgaagacc aagcaggacgtggccgagatgtgggtgggactcagtcagatcagagccctgctcccggtg caaatgagtcaagaagaggaggaactcatgaggaaaaggctttggaaactggtcaacaac cacactttcttccagcatccagatctgataagagtattgagggtacacgaaaacgtgatg gctgtaatgatgaatactttgggaaggagagcccaagcgcagtctgatgctgcaccgaac cagccgcttgccgaggataccaaggagaaggacacttcgcatgaaatggttgtggcctgt tgtcgattcctctgctacttctgtcgcaccggtcgtcagaatcaaaaagccatgttcgat cactttgacttcttgctggagaactccaatattctactgtcgagaccttcgttgcgaggt tcgactcctttggatgttgcctactccagtttgatggagaacacggaattggctttagct ttgagggagcactatcttgagaaaatagcggtatacctttctcgttgtggactacagagc aactctgagttagtggaaaaggggtatccagaccttggatgggatccggtagaaggcgag agatatttggacttcctgagattttgtgtttgggtaaatggtgaaagcgtagaagaaaac gccaacttagtgatccgcttgctaatcaggcggccggagtgtcttggcccggcccttcgg ggagaaggcgaaggtctactgaaggctattgtggacgcgaacaaaatgagcgaaaggatc gcagatagaagaaaactaagagagatagaacaggaaggggatattaatttcagccatcca ctcccggagtcggacgacgacgaggattacatcgatactggagcggccatacttaacttc tactgcaccctggtcgatctgctggggcgctgtgctccggatgcggcagtaattgctctt ggtaagaacgagtcgcttcgggcccgtgccattctgcgctccttggtaccgttggaagat cttcaaggagtgctcagtcttcggttcaccctcaacaatcccgctgccggtgaagagaga cccaagtccgacatgccatccggactaatcccgggacacaagcagagcgtcggacttttc ttagaacgagtctatggcatcgagacccaagagcttttctacaagcttctcgaagaagct ttcttgccagacttgagagctgccactatgctagacaggaacgacggctgcgaatcggac atggcgctttcaatgaaccggtacatcgggaattcgatcctcccgctgctgatcaaacac gccaacttctacaacgaagccgagaactacgccagtctgctggacgccacgctgcacacc gtctacagattatccaaaaaccgcatgctgacaaaaggccaacgtgaggctgtctccgac ttcttggtggctctgacgtcagcgatgcagccctccatgctgttgaagctgctgaggaag ctcacggttgacgtctcgagactgtccgagtacaccaccgtggctctcagactcctgacg ctgcactacgaacgttgcgccaagtactacggcagcactggtgggcagggaatatacgga gcatcttctgatgaggagaagcgtctcaccatgatgctcttctctaacatcttcgattcc ctcagcaagatggactacgaacccgagctgtttgggaaagctttaccctgtctcatcgct ataggctgtgctctaccaccagactactctctatcgaagaattacgacgatgaattctat ggaaaggagcaagcatcagtaggctccgacaacccgcagtacgatccccagccgatcaac acctcatcagtcgccctgaacaacgacttgaacacgatcgtgcagaagttctccgagcat taccacgacgcctgggcctccaggaaaattgagaacggctgggtgtacggcgagtcttgg tcagacagccagaagacgcatccacgactgaagccttacaacatgctcaatgactatgag aaagagcggtacaaagaaccggtccgcgagtcgctgaaggcacttctggctctgggctgg tccgtggaacattccgacgtagacctgcccgccaacagtcgcggctctgtgcgaagacag tccaagtccggactgcgttcgtctgaattaccgaccgactcagcaacccctttcaactac aaccctcaccccgtggacatgacgaatctgacgctgtccagagaaatgcagaacatggcc gagagactggctgacaacgcacatgacatctgggctaagaagaaaaaagaagaactagtt actaatggagggggaatccatcctcaactagttccttacgacctcctaactgataaagaa aagaagaaagaccgagaacgctcacaggagttcctcaagtacctccaatatcagggctat aagctgcacaggccaagcaaaatcccgcagagcgacacggaacagacctctgccggagtg gcaatagagctgagattcgcttactcgttgctagaaaagttgatccagtacatagacagg gctacaatcaacatgaaactcctgaagccatcgacgacgttcagtcgtagaagcagcttc aagacaagcaccagagatataaagttcttctcgaaagtggttctccctctaatggagaag tacttctcgacccatcgcaactacttcatagcggttgcaactgccaccaataatgtggga gccgcgagccttaaagagaaagaaatggtcgccgctttgttctgtaagctggccagcctg cttcgatctagactagcagcttttggccccgacgtccgcatcaccgttcgctgtctccaa gtcctcgtcaagggcattgacgctaaatctctggtcaaaaactgcccggaattcattcgg acttcaatgctgacctttttcaacaacatggccgacgatgttgggcacaccatcattaat ttgcaggatggcaagtacgcgcacctccgcggtacccatttgaaaacgtctacatctctt ggatacattaacggagtacaattacctgtactgactgctatgttcgatcacctagcgaac tgcgaatacggatcagatctgcttttggacgaaattcaagttgcgtcatacaagatgctc gggtcactctacacgttgggcactgatgtaacgctgacccacgaccgcaagtacttgaag acggagattgaaagacacaagcctgctttgggttcgtgtctgggcgctttcagttcaacc ttccccgtggcgtatctggagccgcatctcaacaaacacaaccagttttctctgcttaac aggatcgctgagcattcgctcgaggcccaagatataatggcgaaaatggagcaatctatg ccgactctagagacgatcttgaacgaagtggaccaattcgttgaatcagacaagacgtat aatgaagcgccgcatattatcgacgtggtcctgccattactgtgctcttacctgccgttc tggtgggcgcagggacccgacaacgtcacccctactggagggaaccacgttaccatggta acggcggagcacatgaaccaactcctcaagaacgtgctcaaactaatcaaaaagaacatc ggcaatgaaagcgccccgtggatgacgaggatcgccacttacacccagcagatcatcatc aacagctccgaagagttgctcagggattccttcctgcctctcgccgagagagtcaggaaa cgaacagacaatatgttccacaaggaagagagcttgaggggcttcataaagtcctcgacc gacgacacttcgcaagtagagtctcagatacaagaagactggcagttactggtgcgagac atctactccttctatccgcttctcatcaagtacgtggacttgcagaggaatcactggttg aggaataatgttccagaggccgaggagctatacaaccacgtggccgaaatcttcaacatc tggtcgaagagtcaatacttcttgaaggaagaacaaaactttatatcggcaaacgaaatc gataatatggtcttgataatgccaacagccacacgccgagtcacggccgtggtcgacggc acgtcgcaaagtggtgggaagaaaaagaagaagcatcgcgacaagaaacgtgacaaggac aaggaagttcaggcgtctctgatggtcgcctgtctgaagcggttgctgccggtaggactg aatctcttcgctggaagggaacaggaactggtacagcactgcaaggataggttcctgaag aaaatgtccgagcatgacgttgccgaattcgcgaagacccagctgacgctaccggataaa atagacccggccgacgagatgtcgtggcaacactacctctacagcaaattagggtcgaaa agcaagactgccatcactctggagaatgccgagaacaaagcgaaaatcatcgacgacacc gttgagaggatcgtcgcgatgagcaaagtgctcttcggattgcatatgatcgaccatccg caacaaatgagcaagaacgtttatcgatcagtggtctccatacaaaggaagagggccgtg atagcgtgtttcagacagacgtccctacattcgctgccgagacatcgtgcttgtaacatc ttcgcgaggacttattacgagctgtggctggaggaagaaaacatcggacaagaagtcatg attgaggatttgacgcaatcgttcgaggatgctgaactcaagaagagtgatgtggtagag gaggatgggaagccagatccactgacccagttggtcacgaccttctgcaggggagctatg acggaacggtccggagccttgcaggaagatccactgtacatgtcgtacgcgcatatcatt gcgaagtcatgcggagaagaggaggaggaaggaggcggagaggaggaggagggaggagga gaagcggaaggggaagaggaaggtcgggccagtatacacgagcaagaaatggagaagcag aagctactcttccaccaggcgaggctcgccaacaggggggtcgcggagatggtgctccta cacatatctgcgtccaagggggtgcccagtgaaatggtcatgaaaacgctacagctcggc atatccatactgcgcggcgggaacattgacatacagatgggaatgctgaaccatttgaaa gacaagaaagacgtgggcttcttcacgtccatagctggcctcatgaactcttgctctgtg ttggatctggatgccttcgaaaggaacactaaggctgaaggtctcggggtggggctggag ggagccgccggcgaaaagaacatgcacgacgcagagttcacgtgcgctctcttcagattc atccagctgacttgcgaagggcacaacttggattggcagaactacctccggacccaggcc gggaacacgactaccgtgaacgtcgtgatctgcactgtggactacctgctacgtctccag gagtccatcatggacttctactggcactattcgagcaaggaactgatcgacccggccggt aaagcgaacttctttaaggcgatcggcgtcgcttcgcaagtcttcaacacgctcactgaa gtcatccagggaccttgtactcagaaccagcaggccttagcccactccagactgtgggac gctgtgggagggtttctcttcctgttctcgcacatgcaggacaagctgtcgaagcactcg tcacaagtggacctgctgaaggagctactcaatttgcagaaggacatgatcaccatgatg ctttcgatgctcgaaggaaacgtcgtcaatggtaccatcggtaagcagatggtggacaca ttagtagagtcggcttcaaacgtggaactgatcctcaagtacttcgacatgttcctgaag ctgaaggacttgacctctagcgccagtttccaagaaatcgacgccaataacgacggctgg gtcctgccgaaagacttcaaagagaagatggaacagcaaaagagttacacgcccgaagag atagagttcttactcgcttgctgcgagacgaaccacgacggtaaacttgactacgtgggc ttctgcgaccgtttccacgaaccggccaaagaaatcggcttcaaccttgccgtactgctg accaacctctcggagcacatgcccaacgaaccaagattggcccgtttcctggaaacagct ggctcggtgctgaactacttcgagccattcctcggccgcatcgagatcatgggtggatcg aagcgcatcgaacgagtctactttgagatcaaagaatctaatattgaacagtgggagaag ccgcagatcaaggaatcaaagcgcgcgtttttctacagcatcgtaaccgaaggcggcgac aaggagaagctggaagcgttcgtgaacttctgcgaggacgccatctttgagatgacccac gcgtcgggtctgatggccgcttcggacgacaccgccggcggacctaagaacagggaggcc agctacatgtacatgggagacgacgatgatgatcgtgccggcaaggatccgttccgtcgc ggcatccaatcagtgaaagacggcatctccacggcgttctcgtctttatcaccgtcgaac ataaaggcgaaaattgcagatctacagcaaatgccaccggcagaattggccgtcggcttc ttcaaaatgttcttctatatgttctattacttgggctatggagtgctggtcgttgtcagg tacatattcggagtgctccttggactaatgcggggcccgcaggtggaggagccaccacca gagccaactgaagaggagaaaatcggtcagttaagacacaggttgctcgcgaatcaaagt ccgagacatctgccagctttaccgcctgctgatgacactggacagatgcaagtctcggcc ttcggtttggacataactaaagaagacaacgggcagatccaggtgaagccgcacgagtct cctactacatcgacgccgtcttcaggtgaagaggctgacgcgtctctcgacgagggactg gaacactccgaagagcaacgaccaccgtcgctgatcgacttattaggcggggaacaagca aagaaacaagctctagagcgcattgaggctcaggccgcgcaacaggccgccatgtcggcg atcgaggccgagagcaagaaggccgtccagggtcctgcttcgtcgtcagctctctcccaa gtggatctgtcgcagtacacacggcgagccgtttcgtttttggccagaaacttctacaac ttgaaatacgtggccctcgtgctggctttttgcatcaacttcgtgcttttgttttataag gtttcgactcttgatggcgaaaaagccgaaggttcgggcatcggagatatcattgcgggg tctggttctgggcaaggctctggcagtggtgacggaagcggcgaagaagacgacgcatta gaagtggtacatatcgatgaagacttcttctatatggagcacgtcatcaaagtggcagcg gtcctgcattccatcgtgtccctggctatactgatcgggtattatcatttgaaggtaccg cttgcgatcttcaaacgcgagaaggaaatagctcgtaaactggagtttgacggcctgtac atcgccgagcaacccgaagatgatgacttcaaaagtcattgggataaactcgtcatatcc gctaagtccttccctgtgaactattgggacaaattcgtgaagaagaaagtacgagctaag tactctgagacctacgacttcgattcaatatcgaatatgctcgggatggagaagacttcg ttctcagctcaagaagacgaaggcagcaaggggttgctccactacattataaacatcgac tggcgttaccaagtgtggaaggccggcgtcacgataacggacaactccttcttgtactcg ctgtggtatttcgctttctcggtcatgggaaatttcaataatttcttcttcgcggcccat ctactggacgtcgccgtcggcttcaagactctaaggacgattcttcaatcagtaacacat aatgggaaacagctcgtcttaacagtgatgttgcttacgatcatcgtgtacatatacact gtgatcgctttcaatttcttccgcaagttctacgtccaggaggaagatgacgaggtcaac cggaactgtcatgacatgctgacgtgcttcgtgttcaacctgtacaagggagtgcgcgcc ggcggtggtatcggggacgagctggagccgcccgacggagacgactccgaggtctacagg atcatattcgacatatccttcttcttcttcatcatcgtcattctgctggccattttgcag ggtttgatcatcgatgccttcggtgagctccgtgaccagctcgagtccgtgaaggaggac atggagtccaactgctttatatgcggcatcaataaagactactttgataaggttccacat gggttcgatacgcacgtgcagcgagaacataatttagcgaattacatgttcttccttatg catctcatcaataaaccagacacggaatacaccggtcaagaaacatacgtatggaacatg tacacgcagcgttgctgggacttcttcccggtcggtgactgcttcaggaagcaatacgaa gatcttatgggagaataa

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