Bacillus velezensis JS25R: NG74_00473
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Entry
NG74_00473 CDS
T03423
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bmp
Bacillus velezensis JS25R
Pathway
bmp00300
Lysine biosynthesis
bmp00550
Peptidoglycan biosynthesis
bmp01100
Metabolic pathways
bmp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bmp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NG74_00473 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NG74_00473 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NG74_00473 (murF)
Enzymes [BR:
bmp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NG74_00473 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AIU80630
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Position
462300..463670
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AA seq
456 aa
AA seq
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MIKRTVKRIADMVKGTLTNPVFEQTMIEGAATDTRTLEKNQLFIPLKGEHFNGHTFVPQA
FEKGVSAVLWDRSEPNPPEERAVILVDDTLEALQTLAKAYLKELGTRVIGVTGSNGKTTT
KDMLHAVLGTQYRVHKTAGNFNNHIGLPLTVLAMPEDTEIAVLEMGMSARGEIDFLSRLA
EPEAAVITNIGESHMQDLGSREGIAEAKLEIINGLREDGVLFYFGDEPLLREKTYTCRTT
TYGAGADNDLRLKEIKQAEEGTYFNIDGIDRSFFIPVLGRHNVMNAMAAYAAGIYFGITP
ENAALGLSRLKVTGMRLELVKTENGISIVNDAYNASPTSMKAAVELIETMKGYRKKMLVL
GDMLELGDEEKAFHEECGAAVNPAEIDHVFTYGTLGAFIADGARRHFEEGRVSHYLDKKE
LLHAIQDMAASGDLLLFKASRGMKLEEIVKDLLEKH
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
ttgataaagcgaactgtaaaacgaatcgcagatatggtcaaaggcacactgacaaatccc
gtatttgaacaaacaatgattgagggcgccgcaaccgatacgcggactttggaaaaaaat
cagctgttcattcctttaaaaggcgagcattttaacggccacacctttgtgccgcaagca
tttgaaaaaggcgtttccgcggtgttgtgggaccgctctgaaccgaatccgccggaagag
cgtgctgtcatcctggtcgatgacacgctggaggcgctgcaaacattggcaaaagcttat
ttgaaagagctcggcacacgggttatcggggtgactgggagcaacggaaaaacgacaacg
aaagacatgcttcacgccgttctcggcacgcagtaccgcgttcacaaaaccgccggcaat
ttcaacaaccatatcggcctgccgctgaccgtgcttgccatgcctgaagatacagaaatc
gccgttttagaaatgggaatgagcgcgagaggcgaaattgattttctgagccgtcttgct
gaaccggaagctgccgtcattaccaatatcggcgaatcccacatgcaggatttaggctca
agagaaggaattgcggaggcaaaacttgaaattataaacggacttcgggaagacggcgtt
ctgttttatttcggggatgagccgctgcttcgcgaaaagacgtacacttgccggacaacg
acatacggcgcaggcgcggacaatgatctccgcctgaaagaaataaaacaggcggaagaa
ggcacgtactttaatatcgacgggatcgaccgttctttctttattcccgttctcggcaga
cataatgtgatgaatgccatggccgcatacgccgccggcatctatttcggcattacgccg
gaaaatgccgctctgggactgagccgcctgaaggtgacggggatgagattggaactggtc
aaaacggaaaacggcatctcgatcgtaaacgacgcatataatgcgagcccgacgtcaatg
aaagcggcggtcgaattaatcgaaacgatgaaaggctatcggaagaaaatgctcgtgctc
ggtgatatgcttgaacttggtgatgaagaaaaagcattccacgaagaatgcggtgctgcg
gtcaatccggcggaaatcgaccatgtatttacttacggcacactcggcgcattcatcgct
gacggagcacgccggcattttgaagaagggcgcgtcagccattatcttgacaaaaaagaa
ctgcttcacgccatacaggatatggccgcttccggcgatctccttctgtttaaagcatcg
agaggtatgaagctcgaagaaatcgttaaagatttattagagaagcactga
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