Brucella microti: BMI_II518
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Entry
BMI_II518 CDS
T00955
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bmr
Brucella microti
Pathway
bmr00280
Valine, leucine and isoleucine degradation
bmr00640
Propanoate metabolism
bmr00785
Lipoic acid metabolism
bmr01100
Metabolic pathways
bmr01110
Biosynthesis of secondary metabolites
bmr01210
2-Oxocarboxylic acid metabolism
Module
bmr_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bmr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BMI_II518
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BMI_II518
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BMI_II518
Enzymes [BR:
bmr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BMI_II518
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ACU49650
UniProt:
C7LI12
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Position
2:502370..503602
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AA seq
410 aa
AA seq
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MSDDVVLSLHVPEPEWRPGDAPDFSHVKIPRAGSVRRPEIDEKPEAMRDMAFSIIRVLNR
EGEAVGPWAGTLTDEELKDGLRHMMMLRAYDARMMMAQRQGKTSFYMQHLGEEAVSCAFR
KALRKGDMNFPTYRQAGLLIADDYPLVTMMNQIFSNEQDPLKGRQLPVMYSSKEHGFFTI
SGNLATQYTQAVGWAMASAISHDTKIAAAWIGDGSTAESDFHAALVFASTYKAPVVMNIV
NNQWAISTFQGIARGGSGTFAARGHGFGIPSLRVDGNDYLAVHAVAKWAVERARRNLGPT
TVEYVTYRAGGHSTSDDPSAYRPKAENDAWPLGDPILRLKNHLIKRGVWSEERHKQAEAE
VMDIVVSAQREAEAIGTLHDGRKPSMRDMFEDVYAETPPHLIRQRQEAGF
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgatgtcgtactttcactgcatgttcccgagccggaatggcgcccgggtgat
gcgccggatttctcccacgtcaagattccccgtgcaggcagcgtgcgcaggcccgaaatc
gatgaaaagccggaagccatgcgcgatatggcgttcagcatcatccgcgtgctgaaccgg
gaaggtgaggcggttggcccatgggcgggcacgcttaccgacgaggaactgaaggacggg
cttcgccacatgatgatgttgcgtgcctatgatgcgcgcatgatgatggcgcaacgtcag
ggcaaaacctcgttctacatgcagcatctgggtgaagaggcggtgagttgcgccttccgc
aaggcgctgcgcaagggcgacatgaatttcccgacctaccgccaggcgggccttctcatc
gcggacgactatcccctcgtcacgatgatgaaccagatattctccaacgagcaggacccg
ctgaaaggccgccagcttccggtgatgtattcctcgaaagagcatggctttttcaccatt
tccggcaatctggcgacgcaatatacgcaggccgtcggctgggcgatggcatcggccatc
agccacgacacgaagattgccgccgcatggatcggtgacggctcgacggcggaaagcgat
ttccacgccgcactggtcttcgcctcgacctacaaggccccggtggtgatgaacatcgtc
aacaaccaatgggctatttccacctttcagggcattgcgcgcggcggttccggcactttt
gcggcgcggggccacggcttcggcattccgtcgctgcgcgtcgatggcaatgactatctg
gccgtccatgcggtggcgaaatgggcggtcgaacgcgcgcggcgcaatctcggcccgacc
accgtggaatatgtgacctatcgcgccggcgggcactccacttcggacgatccgtccgcc
tatcgccccaaggcggaaaatgacgcatggccgcttggcgatccgatcctgcggctcaag
aaccacctcattaagcgcggcgtgtggtcggaagagcgccacaagcaggcggaagccgag
gtgatggatattgtggtgagtgcgcagcgcgaggcggaagccatcggcacgctgcatgat
ggccgtaagccctccatgcgcgacatgttcgaggatgtctatgccgaaacgccgccgcat
cttatccgccagcgtcaggaggcggggttttga
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