Burkholderia multivorans ATCC 17616 (JGI): Bmul_0489
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Entry
Bmul_0489 CDS
T00624
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bmu
Burkholderia multivorans ATCC 17616 (JGI)
Pathway
bmu00290
Valine, leucine and isoleucine biosynthesis
bmu00620
Pyruvate metabolism
bmu01100
Metabolic pathways
bmu01110
Biosynthesis of secondary metabolites
bmu01210
2-Oxocarboxylic acid metabolism
bmu01230
Biosynthesis of amino acids
Module
bmu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Bmul_0489
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Bmul_0489
Enzymes [BR:
bmu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Bmul_0489
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
BP74_N
Motif
Other DBs
NCBI-ProteinID:
ABX14184
UniProt:
A0A0H3KMB2
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All DBs
Position
1:complement(534937..536583)
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AA seq
548 aa
AA seq
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MKRNPQEKYRAFEPVRLNGRKWPTRTIERAPVWMSTDLRDGNQSLIEPMSIEQKLEFFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIDEKRIPDDVTIEVLVQSREDLIARTFEALEGV
PRAIVHLYNAICPSFRRIVFGMSKDDVKALAVEGTRLIKAYAAARPDTQWTYQYSPETFS
MTELTFAREVCDAVAQMWRPTRDHKMIVNLPATVEAAMPNVFADQIEWMDRNLAYRDSIV
LSVHPHNDRGTAVAAAELALLAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNQIPVHPRHPYAGDLVFTAFSGSHQDAIRKGFAQQRADALWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATYLLERGMGFTPTRRVQIEFSHAVQTLADASGAE
VTGDAICALFAREFLETDGPAARHGNGARWQNREIAGAFAADAAPEAAVQRAAAAFAAAA
GATIDVASCEHVRTADGRIAVSVGCRVGDAPLRHGVGVHADASCAALDAVVSAINRSAWQ
HADRRAAA
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcaacccgcaagaaaagtaccgagcgttcgaacccgtccgcctcaacggccgc
aagtggccgacccgcacgatcgagcgggcgccggtgtggatgagcaccgacttgcgcgac
ggcaaccagtcgctgatcgaaccgatgagcatcgagcagaaactcgagttcttcgagatg
ctggtcgcgatcgggttcaaggagatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgttcgcaagctgatcgacgagaagcgcatccccgacgacgtgacgatcgaa
gtgctcgtgcagtcgcgcgaagacctcatcgcccgcacgttcgaagcgctcgaaggcgtg
ccgcgtgcgatcgtgcatctgtacaacgcgatctgcccgtcattccgccgcatcgtgttc
gggatgtcgaaggacgacgtgaaggcgctcgcggtcgaaggcacgcggctcatcaaggca
tacgcggccgcgcgcccggacacgcagtggacctaccagtattcgccggaaaccttcagc
atgaccgagctgacgttcgcgcgcgaagtgtgcgacgcggtcgcgcaaatgtggcgtccg
acccgcgaccacaagatgatcgtcaacctgccggcgaccgtcgaagccgcgatgccgaac
gtgttcgccgatcagatcgaatggatggaccgcaatctcgcgtatcgcgacagcatcgtg
ctgtccgtgcatccgcacaacgatcgcggcaccgcggtcgcggccgccgaactcgcgctg
ctcgccggcgcggaccgcatcgagggctgcctgttcggcaacggcgagcgcaccggcaac
gtcgatctcgtcacgctcgcgctcaatctgtatacgcaaggcatcgatccgggcctcgac
ttctccgacatcgatgcggtgcgccgcgtcgtcgaacgctgcaaccagattcccgtgcat
ccgcgccacccgtacgcgggcgacctcgtcttcaccgcgttctccggctcgcaccaggac
gcgatccgcaagggcttcgcgcagcaacgcgcggacgcgctgtgggaagtgccgtatctg
ccgatcgatccggccgatctcggccgcagctacgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgacgtacctgctcgagcgcggcatgggctttacgccgacgcgc
cgcgtgcagatcgaattcagccatgcggtgcagacgctcgccgatgcgtcgggcgccgaa
gtcaccggcgacgcgatctgcgcgctctttgcccgcgaattcctcgaaaccgacggcccg
gccgcgcggcacggcaacggcgcgcgctggcagaaccgcgagatcgcgggcgcgttcgcg
gccgacgcagcgcccgaagcggccgtgcagcgcgcggccgcggcattcgcggcggccgcc
ggcgcgacgatcgacgtcgcgtcgtgcgagcacgtgcgcacggccgacggccggatcgcc
gtgtcggtcggctgccgcgtcggcgatgcgccgctgcggcacggcgtcggcgtccatgcc
gacgcgtcgtgcgcggcgctcgatgcggtcgtcagcgcgatcaatcgctccgcgtggcag
cacgcggatcggcgcgcggccgcctga
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