KEGG   Balaenoptera musculus (blue whale): 118886231
Entry
118886231         CDS       T09887                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus01521  EGFR tyrosine kinase inhibitor resistance
bmus01522  Endocrine resistance
bmus04012  ErbB signaling pathway
bmus04066  HIF-1 signaling pathway
bmus04140  Autophagy - animal
bmus04150  mTOR signaling pathway
bmus04151  PI3K-Akt signaling pathway
bmus04152  AMPK signaling pathway
bmus04211  Longevity regulating pathway
bmus04213  Longevity regulating pathway - multiple species
bmus04350  TGF-beta signaling pathway
bmus04371  Apelin signaling pathway
bmus04666  Fc gamma R-mediated phagocytosis
bmus04714  Thermogenesis
bmus04910  Insulin signaling pathway
bmus04931  Insulin resistance
bmus05163  Human cytomegalovirus infection
bmus05165  Human papillomavirus infection
bmus05170  Human immunodeficiency virus 1 infection
bmus05200  Pathways in cancer
bmus05205  Proteoglycans in cancer
bmus05207  Chemical carcinogenesis - receptor activation
bmus05210  Colorectal cancer
bmus05212  Pancreatic cancer
bmus05221  Acute myeloid leukemia
bmus05224  Breast cancer
bmus05225  Hepatocellular carcinoma
bmus05226  Gastric cancer
bmus05231  Choline metabolism in cancer
bmus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    118886231 (RPS6KB1)
   04350 TGF-beta signaling pathway
    118886231 (RPS6KB1)
   04371 Apelin signaling pathway
    118886231 (RPS6KB1)
   04066 HIF-1 signaling pathway
    118886231 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    118886231 (RPS6KB1)
   04152 AMPK signaling pathway
    118886231 (RPS6KB1)
   04150 mTOR signaling pathway
    118886231 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118886231 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    118886231 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118886231 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    118886231 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    118886231 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    118886231 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118886231 (RPS6KB1)
   05205 Proteoglycans in cancer
    118886231 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    118886231 (RPS6KB1)
   05231 Choline metabolism in cancer
    118886231 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118886231 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118886231 (RPS6KB1)
   05212 Pancreatic cancer
    118886231 (RPS6KB1)
   05225 Hepatocellular carcinoma
    118886231 (RPS6KB1)
   05226 Gastric cancer
    118886231 (RPS6KB1)
   05221 Acute myeloid leukemia
    118886231 (RPS6KB1)
   05224 Breast cancer
    118886231 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118886231 (RPS6KB1)
   05163 Human cytomegalovirus infection
    118886231 (RPS6KB1)
   05165 Human papillomavirus infection
    118886231 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    118886231 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118886231 (RPS6KB1)
   01522 Endocrine resistance
    118886231 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bmus01001]
    118886231 (RPS6KB1)
Enzymes [BR:bmus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     118886231 (RPS6KB1)
Protein kinases [BR:bmus01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   118886231 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 118886231
NCBI-ProteinID: XP_036691544
UniProt: A0A8B8W393
LinkDB
Position
20:35469121..35505801
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQAPVEYPMETSG
IEQMDVTVSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggtttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggagcattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgagtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaataccgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaacagattttggactatgc
aaagaatctattcatgacggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtctggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagttcaagctcatccattcttcagacatattaactgggaagaactg
ctggctcggaaggtagagcccccctttaaacctctgttgcaatctgaagaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctg
agtgaaagtgccaaccaggtctttctgggttttacatatgtggctccatctgtacttgaa
agcgtgaaagaaaagttttcctttgaaccaaaaatccggtcacctcgaagatttattggc
agcccacgaacacctgtcagccctgtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacggcaaatcctcaggcgcctgtggaatacccaatggaaacaagtgga
atagagcagatggatgtgacggtgagtggggaagcttcagcaccacttccaatacgacag
ccgaactccgggccatacaaaaaacaagcttttcccatgatctccaaacgaccagaacac
ctgcgtatgaatctatga

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