KEGG   Balaenoptera musculus (blue whale): 118886696
Entry
118886696         CDS       T09887                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus04010  MAPK signaling pathway
bmus04015  Rap1 signaling pathway
bmus04218  Cellular senescence
bmus04380  Osteoclast differentiation
bmus04620  Toll-like receptor signaling pathway
bmus04664  Fc epsilon RI signaling pathway
bmus04668  TNF signaling pathway
bmus04750  Inflammatory mediator regulation of TRP channels
bmus04912  GnRH signaling pathway
bmus04935  Growth hormone synthesis, secretion and action
bmus04936  Alcoholic liver disease
bmus05014  Amyotrophic lateral sclerosis
bmus05022  Pathways of neurodegeneration - multiple diseases
bmus05132  Salmonella infection
bmus05135  Yersinia infection
bmus05145  Toxoplasmosis
bmus05161  Hepatitis B
bmus05163  Human cytomegalovirus infection
bmus05167  Kaposi sarcoma-associated herpesvirus infection
bmus05169  Epstein-Barr virus infection
bmus05170  Human immunodeficiency virus 1 infection
bmus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bmus05417  Lipid and atherosclerosis
bmus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118886696 (MAP2K6)
   04015 Rap1 signaling pathway
    118886696 (MAP2K6)
   04668 TNF signaling pathway
    118886696 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    118886696 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118886696 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    118886696 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118886696 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    118886696 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118886696 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118886696 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118886696 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118886696 (MAP2K6)
   05161 Hepatitis B
    118886696 (MAP2K6)
   05163 Human cytomegalovirus infection
    118886696 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118886696 (MAP2K6)
   05169 Epstein-Barr virus infection
    118886696 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118886696 (MAP2K6)
   05135 Yersinia infection
    118886696 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118886696 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118886696 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    118886696 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118886696 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    118886696 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118886696 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bmus01001]
    118886696 (MAP2K6)
Enzymes [BR:bmus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     118886696 (MAP2K6)
Protein kinases [BR:bmus01001]
 Serine/threonine kinases: STE group
  STE7 family
   118886696 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 118886696
NCBI-ProteinID: XP_036692671
UniProt: A0A8B8W6E4
LinkDB
Position
20:2453365..2587654
AA seq 389 aa
MPNSQQGEKGRSSWVKRIGSLILTFPPGLVKNLTRDLSLHLGSSAQPGDWSLSFTAVLVG
GKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYG
VVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDV
WICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNV
LINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGI
TMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADEFSDEFADFTSQCLKKNSKERPTY
PELMHHPFFTLHESKATDVASFVKSILGD
NT seq 1170 nt   +upstreamnt  +downstreamnt
atgccgaactcccagcagggagaaaagggcaggtcttcctgggtaaagagaattggcagc
cttatactgacatttccccctggactggtgaaaaacctcacccgtgacctcagcctgcac
ttgggaagctctgctcagcctggtgactggagcttgtcattcacagccgtcctggtagga
ggcaagaagcgaaaccctggccttaaaatcccgaaagaagcatttgaacaacctcagacc
agttccacgccacctcgagatttagactccaaagcttgcatttctattggaaatcagaac
tttgaggtgaaggcagatgacctggagcctatagtggagctgggccggggggcgtacggg
gtggtggagaagatgcggcatgtgcccagcgggcagatcatggcggtgaagcggatccgg
gccacagtaaatagccaggagcagaaaaggttactgatggatttggatatttccatgagg
accgtggactgtccttttacggtcaccttttatggcgcactcttccgtgagggggatgtc
tggatctgcatggagctcatggacacgtccctagataaattctacaaacaagtgattgat
aaaggccaaacaattccagaggacatcttagggaaaatagcagtttctattgtaaaagca
ttagaacatttacacagtaagctctctgtcattcatcgagatgtcaagccttccaatgtg
ctcatcaacaccctgggccaggtgaagatgtgcgattttgggatcagcggctaccttgtt
gactctgtcgctaaaactattgatgcaggatgcaaaccgtacatggctcccgagagaata
aacccagagctcaaccagaagggatacagcgtgaagtccgacatttggagtctgggcatc
accatgatcgagctggccatccttcggtttccctatgactcgtggggaaccccttttcag
cagctcaaacaggtggtggaggagccgtcgccacaactccccgcagacgagttctccgac
gagtttgccgacttcacctcgcagtgcttgaagaagaattccaaagaaaggccaacatat
ccagagcttatgcaccatccatttttcaccctacacgaatccaaagcgacagacgtggca
tcttttgtaaaatcgattcttggagactaa

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