Balaenoptera musculus (blue whale): 118887492
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Entry
118887492 CDS
T09887
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118887492 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
bmus03032
]
118887492 (TOP2A)
03036 Chromosome and associated proteins [BR:
bmus03036
]
118887492 (TOP2A)
Enzymes [BR:
bmus01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
118887492 (TOP2A)
DNA replication proteins [BR:
bmus03032
]
Eukaryotic type
DNA Topoisomerases
118887492 (TOP2A)
Chromosome and associated proteins [BR:
bmus03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
118887492 (TOP2A)
Centrosome formation proteins
Centriole proteins
118887492 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
118887492
NCBI-ProteinID:
XP_036694238
UniProt:
A0A8B8WAS5
LinkDB
All DBs
Position
20:complement(19587495..19613537)
Genome browser
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNDNMQVNKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ
MWVYDEDIGINCREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTVDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFRQTWMDNMGRAGEMELKPFSGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPIKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ
IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKLLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
SMPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTID
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETAKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQIGLPGKGGKA
KGKKTQRAEVLPSPCGKRVIPQVTIEMKAEAEKKIKKKIKNENTEGSPQEDGMEIEGLKQ
RLEKKQKREPGTKTRKQTTLPFKPVKKAKKRNPWSDSESDMSSNESNFDVPPREKEPRRA
ATKTKFTMDLDSDEDFSDFDENAQDEDFVPSDASPPGTKTSPKHTNKELKPQKSATSVTD
LNADDAKGNVPPPPSSPAADFPAVTKTINPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAP
KGTKKDPDLDSDVSKKPNPPQTKSRRKRKPSTSDDSDSNFEKMISKAVTSKKPKEDSDDF
HLDLDSAVASRAKSGRTKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccactgcagcctgtaaatgacaatatgcaagtcaacaaaacaaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaagacacaactg
gaacatattctgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa
atgtgggtttacgatgaagatattggcattaactgtagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacagttgacccggagaataatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacaactcctaacttctagtaactatgatgatgaagaaaagaaagtaacgggt
ggtcgaaatggctatggagccaaattgtgtaatatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcagacagacatggatggataacatggggaga
gctggtgagatggaactcaagccctttagtggagaagattatacatgtattaccttccac
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaggtctttctcaatggaaat
aagcttccaataaaaggattccgtagctatgtagatatgtatctgaaggataaggtagat
gaaactggcaatccactgaaaattatccacgaacaagtaaaccccaggtgggaagtgtgc
ttaacaatgagtgaaaagggctttcagcaaatcagctttgtcaacagcattgccacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaaaaagaacaagggtggtgttgcagtaaaagcacatcaggtaaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaaccttcgactcccagacaaaagagaac
atgactttacaagtcaagagctttggatcaacatgccaactgagtgaaaaattcatcaaa
gctgcaactggctgtggtattgtagaaagcatactaaattgggtgaaatttaaggcccaa
atccagttaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattcccaaa
cttgatgatgccaatgatgcaggaggccgaaactctactgagtgtacacttatcctgaca
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaag
tacggagttttccctcttagaggaaaactgcttaatgttcgagaagcttctcataaacag
ataatggaaaatgctgaaattaacaatataatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactctgcgttatgggaagataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcataac
tggccctctcttctgcgacatcgttttctggaagaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagccttcctgagtttgaagaatggaagagt
tctatgccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagagtactttgcagatatgaaaagacatcgtatccaattcaaatat
tcaggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaagatagaaggcaacgaaagttacttggcctt
cctgaggattacttatatgggcaaactaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagaggtctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaactttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcacacgttaaagtttttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtgctgataaatggcgctgaagggattggtactggctgg
tcctgcaaaatccccaactttgatgttcgtgaagttgtgaataacatcagacgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgac
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattctacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatataaagaacaggttcta
gaacccatgttgaatggcactgagaagacaccccctctgataacagattatagggaatac
cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaaactggcagaggca
gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatacgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggcgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaacaagcctaagaaagaattaattaaagttctgattcaaaga
ggttatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgcaaagagtgactctgtaacagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaaccaaggaaaag
aaagatgaactgtgcaaactaagaaatgaaaaagagcaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagagctggaggct
gttgaagcaaaggagaaacaagatgaacaaataggacttcctgggaaaggtgggaaagca
aaggggaaaaaaacacaaagggcagaagttttgccttctccatgtggaaaaagagtcatc
ccccaagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaaaaaaattaag
aatgaaaatactgaaggaagccctcaagaggatgggatggaaatagaaggcctaaaacag
agattagaaaagaaacagaaaagagaaccaggtaccaagacaaggaaacaaactacattg
ccatttaaaccagtcaagaaagccaaaaagagaaacccctggtctgattcggaatcagat
atgagcagtaacgaaagtaattttgatgtccctccccgagaaaaagagccacggagagca
gcaacaaaaaccaaattcacaatggatttggattcagatgaagatttctcagattttgat
gaaaacgctcaagatgaagattttgtcccatcagatgctagtccacctgggaccaaaacg
tccccaaaacatactaacaaagaactgaagccacagaaaagtgccacatcagtaacggac
cttaacgctgatgatgccaagggtaatgtaccacctcctccaagctctcctgctgctgat
ttcccagctgtaactaaaaccataaaccctgttcctaaaaagaatgtgacagtgaagaag
acggcagcaaaaagtcagtcttccacctctactacaggggccaaaaaaagggctgcacca
aaaggaaccaaaaaggatccagacttggattctgatgtctctaaaaagcctaatcccccc
caaaccaagagtcgccgcaagaggaagccgtccacttctgatgattccgactctaatttt
gagaaaatgatttctaaagcagtcacaagcaagaaacccaaggaggacagcgatgacttc
catctggacttagactcagctgtggcttctcgggcaaaatctggacggacaaaaaaacct
ataaagtacctcgaagaatcagatgaagatgatctgttttaa
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integrated database retrieval system
