Balaenoptera musculus (blue whale): 118888539
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Entry
118888539 CDS
T09887
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00010
Glycolysis / Gluconeogenesis
bmus00020
Citrate cycle (TCA cycle)
bmus00620
Pyruvate metabolism
bmus00785
Lipoic acid metabolism
bmus01100
Metabolic pathways
bmus01200
Carbon metabolism
bmus01210
2-Oxocarboxylic acid metabolism
bmus04066
HIF-1 signaling pathway
bmus04922
Glucagon signaling pathway
bmus05230
Central carbon metabolism in cancer
bmus05415
Diabetic cardiomyopathy
Module
bmus_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118888539 (PDHA1)
00020 Citrate cycle (TCA cycle)
118888539 (PDHA1)
00620 Pyruvate metabolism
118888539 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
118888539 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118888539 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
118888539 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118888539 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
118888539 (PDHA1)
Enzymes [BR:
bmus01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
118888539 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
118888539
NCBI-ProteinID:
XP_036695614
UniProt:
A0A8B8WEM8
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All DBs
Position
X:15819944..15843630
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNEKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgccgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcactacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgttcgtcgaatggagttaaaagcagatcag
ctatataagcagaaaataattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaaccccacagaccatctgatcacagcgtatcgggct
catggctttacgtttactcgtgggctttctgtccgagcaattcttgcagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtacgccaagaacttc
tacgggggcaatggcattgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataacgaaaaagatgaaatctgtttgactttgtatggtgatggcgctgctaat
cagggtcagatattcgaagcttacaatatggcggctttgtggaaattgccttgtattttc
atctgtgagaataaccgctatgggatgggaacatctgtggagagagcggcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagatggaatggatatccta
tgtgtccgggaggccacaaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagttagaagtaagagtgatcctatcatgcttctc
aaggataggatggtgaacagcaatcttgccagtgttgaagaactaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgctacagctgatcctgagccacct
ttggaagaactcggctatcacatctactgcagcgatccgccttttgaagtccggggggca
aaccagtggatcaagtttaagtccatcagttaa
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