Balaenoptera musculus (blue whale): 118889611
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Entry
118889611 CDS
T09887
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus01521
EGFR tyrosine kinase inhibitor resistance
bmus01522
Endocrine resistance
bmus04010
MAPK signaling pathway
bmus04012
ErbB signaling pathway
bmus04014
Ras signaling pathway
bmus04062
Chemokine signaling pathway
bmus04068
FoxO signaling pathway
bmus04072
Phospholipase D signaling pathway
bmus04150
mTOR signaling pathway
bmus04151
PI3K-Akt signaling pathway
bmus04510
Focal adhesion
bmus04540
Gap junction
bmus04630
JAK-STAT signaling pathway
bmus04650
Natural killer cell mediated cytotoxicity
bmus04660
T cell receptor signaling pathway
bmus04662
B cell receptor signaling pathway
bmus04664
Fc epsilon RI signaling pathway
bmus04714
Thermogenesis
bmus04722
Neurotrophin signaling pathway
bmus04810
Regulation of actin cytoskeleton
bmus04910
Insulin signaling pathway
bmus04912
GnRH signaling pathway
bmus04915
Estrogen signaling pathway
bmus04917
Prolactin signaling pathway
bmus04926
Relaxin signaling pathway
bmus04935
Growth hormone synthesis, secretion and action
bmus05034
Alcoholism
bmus05160
Hepatitis C
bmus05161
Hepatitis B
bmus05163
Human cytomegalovirus infection
bmus05165
Human papillomavirus infection
bmus05200
Pathways in cancer
bmus05205
Proteoglycans in cancer
bmus05206
MicroRNAs in cancer
bmus05207
Chemical carcinogenesis - receptor activation
bmus05208
Chemical carcinogenesis - reactive oxygen species
bmus05210
Colorectal cancer
bmus05211
Renal cell carcinoma
bmus05213
Endometrial cancer
bmus05214
Glioma
bmus05215
Prostate cancer
bmus05220
Chronic myeloid leukemia
bmus05221
Acute myeloid leukemia
bmus05223
Non-small cell lung cancer
bmus05224
Breast cancer
bmus05225
Hepatocellular carcinoma
bmus05226
Gastric cancer
bmus05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118889611 (SOS2)
04012 ErbB signaling pathway
118889611 (SOS2)
04014 Ras signaling pathway
118889611 (SOS2)
04630 JAK-STAT signaling pathway
118889611 (SOS2)
04068 FoxO signaling pathway
118889611 (SOS2)
04072 Phospholipase D signaling pathway
118889611 (SOS2)
04151 PI3K-Akt signaling pathway
118889611 (SOS2)
04150 mTOR signaling pathway
118889611 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118889611 (SOS2)
04540 Gap junction
118889611 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118889611 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
118889611 (SOS2)
04660 T cell receptor signaling pathway
118889611 (SOS2)
04662 B cell receptor signaling pathway
118889611 (SOS2)
04664 Fc epsilon RI signaling pathway
118889611 (SOS2)
04062 Chemokine signaling pathway
118889611 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
118889611 (SOS2)
04912 GnRH signaling pathway
118889611 (SOS2)
04915 Estrogen signaling pathway
118889611 (SOS2)
04917 Prolactin signaling pathway
118889611 (SOS2)
04926 Relaxin signaling pathway
118889611 (SOS2)
04935 Growth hormone synthesis, secretion and action
118889611 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
118889611 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
118889611 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118889611 (SOS2)
05206 MicroRNAs in cancer
118889611 (SOS2)
05205 Proteoglycans in cancer
118889611 (SOS2)
05207 Chemical carcinogenesis - receptor activation
118889611 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
118889611 (SOS2)
05231 Choline metabolism in cancer
118889611 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
118889611 (SOS2)
05225 Hepatocellular carcinoma
118889611 (SOS2)
05226 Gastric cancer
118889611 (SOS2)
05214 Glioma
118889611 (SOS2)
05221 Acute myeloid leukemia
118889611 (SOS2)
05220 Chronic myeloid leukemia
118889611 (SOS2)
05211 Renal cell carcinoma
118889611 (SOS2)
05215 Prostate cancer
118889611 (SOS2)
05213 Endometrial cancer
118889611 (SOS2)
05224 Breast cancer
118889611 (SOS2)
05223 Non-small cell lung cancer
118889611 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
118889611 (SOS2)
05160 Hepatitis C
118889611 (SOS2)
05163 Human cytomegalovirus infection
118889611 (SOS2)
05165 Human papillomavirus infection
118889611 (SOS2)
09165 Substance dependence
05034 Alcoholism
118889611 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118889611 (SOS2)
01522 Endocrine resistance
118889611 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
IQ_SEC7_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
118889611
NCBI-ProteinID:
XP_036697394
UniProt:
A0A8B8WJK9
LinkDB
All DBs
Position
2:complement(125852377..125954053)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRLGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRITETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaacggaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatcccaacag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggcttggtttctctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcttttctttctgacagaaagctgtttaaaccttctgatatt
gaaaagattttcagtaacattttagatatacatgaattgaccgtgaaacttttaggttta
attgaagacacagttgaaatgactgatgaaagcagccctcatcccttagctggaagctgt
tttgaagatttggcagaggaacaagcatttgatccttatgaaacattatcacaggatatt
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaatttattatggaaggcccattgacaagaattggtgctaaacacgaacggcatattttt
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccagga
tacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacttgcgagtgcaaacatgcttttgaattagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattattgaaggaagaa
aatgaacaaccacttagattaccgagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggttaacatatcacatgtatgcagatcctaat
tttgttcgcacttttcttactacgtatcgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gtagagaaaggcgagcagccaatcagtgcagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagacttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagactaggacagtttgaaacgtttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccacaccacaaatctcactctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatctgaataatttcaatggtgtattagagatcgtcagtgcagtaaattcagtatca
gtctatagactagatcatacctttgaggcattgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcaatatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaaatgcttctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggtactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattactgaaacagagcttgaatcaacagtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca
gtcctcttgcctcattcaaagtctttctttagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaaatttgatcatgatgcttca
aattccaagggaactatgaaatctgatgatgacccccctgctattccgccaagacagcct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgacgggcctctg
catagtccaccaccgccgccgccgagagatcctcttcccgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccgtttactcttcagccacctccgctggga
catcttcacagagatccagactggttcagagacgttagtacgtgtccaaattctccaaac
actcctcctagcacaccctctccaagggtaccacgtcgatgctatgtgctcagttctagt
caaaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcgcaccccccattgtat
agactgcctttgctagaaaatgcagaaactcctcaatga
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