KEGG   Balaenoptera musculus (blue whale): 118890390
Entry
118890390         CDS       T09887                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus00140  Steroid hormone biosynthesis
bmus01100  Metabolic pathways
bmus04913  Ovarian steroidogenesis
bmus04925  Aldosterone synthesis and secretion
bmus04927  Cortisol synthesis and secretion
bmus04934  Cushing syndrome
Module
bmus_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    118890390
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    118890390
   04925 Aldosterone synthesis and secretion
    118890390
   04927 Cortisol synthesis and secretion
    118890390
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118890390
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:bmus00199]
    118890390
Enzymes [BR:bmus01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     118890390
Cytochrome P450 [BR:bmus00199]
 Cytochrome P450, animal type
  CYP11 family
   118890390
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 118890390
NCBI-ProteinID: XP_036699084
UniProt: A0A8B8WPB5
LinkDB
Position
2:60630336..60643402
AA seq 520 aa
MLARGLPLHSVLVRGCQPLLSTPWEGLGHPRVGTGEGAGISTKTPRPFNEIPTPGDNGWL
NLYRFWREKGSQKIHYHHVQNFQKYGPIYREKLGNLESVYIIDPEDVALLFKFEGPNPER
YNIPPWVAYHQYYQKPIGVLLKKAGAWKKDRLVLNTEVMAPEAIKNFIPLLNPVSQDFVG
VLHRRIKQQGSGKFSGDIREDLFRFAFESITNVMFGERLGMLEEVVDPEAQKFIDAVYQM
FHTSVPMLNLPPDLFRLFRTKTWRDHVAAWDIIFNKAEKYTENFYWDLRRKREFTNYPGI
LYRLLGNDKLLSEDVKANITEMLAGGVDTTSMTLQWHLYEMARSLNVQDMLREEVLNARR
QAQGDTSKMLQLVPLLKASIKETLRLHPISVTLQRYLANDLVLRDYMIPAKTLVQVAIYA
MGRDPAFFSNPDKFDPTRWLGKDRDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE
NFKVELQHLSDVDTIFNLILMPDKPIFLVFQPFNQDPPQA
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgctggccagggggcttcccctccactcagtcctggtcagaggctgccagcccctcctg
agcaccccgtgggagggcctggggcatcccagggtgggcactggagagggagccggcatc
tccactaaaacccctcgccccttcaacgagatccccacccctggtgacaatggctggctt
aacctataccgtttctggagggagaagggctcacagaaaatccactatcaccacgtccag
aacttccagaagtatggccccatttacagagagaagctcggcaatttggagtcagtttat
atcatcgaccctgaagatgtggcccttctctttaagttcgagggacccaacccagaacga
tacaacatcccaccctgggttgcctatcaccagtattaccagaaacccatcggggtcctg
ttgaagaaggcaggagcctggaagaaagaccggttggtcctgaacacggaggtgatggct
ccagaggccataaagaacttcattcccctgctgaacccagtgtctcaggacttcgtcggc
gtcctgcacaggcgcatcaagcagcagggctctggaaagttctcaggggacatcagggaa
gacctgtttcgcttcgcctttgagtccatcaccaatgtcatgtttggggagcgcctgggg
atgctggaggaagtagtggaccctgaggcccagaagttcattgatgccgtctaccagatg
ttccacaccagtgtccccatgctcaacctccctccagaccttttccgtctgttcaggacc
aagacctggagagaccatgtagccgcatgggacataattttcaataaagctgaaaaatac
accgagaacttctactgggacctgagacggaaaagagagttcaccaattacccaggtatc
ctctaccgcctcctgggaaatgacaagctgctctcggaggacgtcaaggccaacattacg
gagatgcttgcagggggcgtggacacgacatccatgacattgcaatggcacttgtatgag
atggcacgcagcctgaatgtgcaagacatgctgcgggaggaggtcctgaatgcccggcgc
caggcccagggagacacaagcaagatgctgcaattggtcccactcctcaaagctagtatc
aaggagacactgagactccaccccatctccgtgaccctacagagatacctcgcaaatgac
ttggttcttcgagattacatgattcctgccaagacattggtgcaagtggccatctatgcc
atgggccgagaccctgccttcttctcgaatccggacaagtttgacccaaccaggtggctg
ggtaaagacagggacctcatccacttccggaacctgggctttggctggggtgtacggcag
tgtgtgggccggcggattgctgagctcgagatgaccctcttcctcatccatattctggag
aacttcaaggttgaattgcagcatctcagtgatgtggacaccatattcaatctcatcctg
atgcccgacaagcccatcttccttgtcttccagcccttcaaccaggacccaccccaggcg
tga

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