Balaenoptera musculus (blue whale): 118890984
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Entry
118890984 CDS
T09887
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00230
Purine metabolism
bmus01100
Metabolic pathways
bmus04927
Cortisol synthesis and secretion
bmus04934
Cushing syndrome
bmus05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118890984 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
118890984 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
118890984 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
118890984 (PDE8A)
Enzymes [BR:
bmus01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
118890984 (PDE8A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS
PAS_9
PDE8_3rd
PAS_4
PAS_3
Response_reg
PAS_8
DUF5894
Motif
Other DBs
NCBI-GeneID:
118890984
NCBI-ProteinID:
XP_036700384
UniProt:
A0A8B8WSX2
LinkDB
All DBs
Position
2
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AA seq
840 aa
AA seq
DB search
MGCAPSIHASESRAVYHGGNEAEDAPGPTAPPLQPGVPRLPPGQTTAASARSCGSSLVES
EPNGGSDSGNGNTVAVADIQFGPMRFHPDQLQVLLVFPKEDKQCNGFCRACEKAGFKCTV
IKEAQTALACFLDKHHDVIIIDHRNPQQLDGEVLCRSIRSSELSENTVIVGVVRRAVREE
SSVMSLIEAGFTRRYVENPSAMACYNELLQMEFGLVRPQLKLRACNSMFTALEKSQEAIE
ITSEDHIVQYANPAFETTMGYESGELIGKDLAEVPVNEKKADLLDTINSCIRIGKEWQGI
CSAKEKNGDNVQQNVKILPVIGQGGKIRHYVSIVRACNGNNKATKIAECVQSDTHTDNQS
GKHNDRRKSSLDVRTAASRTSKVSSQRRRSSMARIHSMKIEAPITKAINIISAAQESSPM
PVTEALDRVLEILRTTELYSPQFDAKDDDPHAIDLVGGLMSDVFRRPARNEYVLSTKNLQ
QVSSSVITPTSLHDIPSQITQALENEESWDFDIFELEAATHKRPLIYLGLKIFARFGVCE
VLKCSETTLRSWMQIIEANYHASNPYHNSTHSADVLHATAYFLCKERIKQTLDPLDEVTT
LIAATVHDLDHPGRTNSFLCNAGSELAILYNDTAVLERHHAALAFQLTTGDDKCNIFKNM
ERNDYRTLRQSIIDMVLATEMTKHFEHVNKFVNSINKPLAALEEDGETDKNQEAIITMPR
TPDNRCLIKRMLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVFDR
NTCSIPKSQISFIDYFITDMFAAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2523 nt
NT seq
+upstream
nt +downstream
nt
atgggttgtgccccgagcatccacgcttccgagagccgggcggtgtaccacggcggcaac
gaggccgaggacgcgccgggccccacggcgccgccgttgcagcccggcgtgccgcgcctc
ccacccggccagacgacggccgcctcggcccggtcctgcggctccagcctcgtggagtcc
gagccaaacggcggcagcgacagcggcaacggcaatacggtagcagtagctgatatacaa
tttggccccatgagatttcatccagatcagctccaggtacttttagtgtttcccaaagaa
gataagcagtgtaatggattctgtagggcatgtgaaaaagcagggtttaagtgtacagtt
atcaaggaggctcagacggcccttgcctgtttcctggacaaacatcatgatgtcatcatc
attgaccacagaaatccccaacagctggacggggaggtgctgtgcaggtctatcagatca
tcagaactctcagaaaacacagttattgttggtgtagtacgcagggcggttagagaagag
tcatctgtaatgtccctcattgaggctggctttacaaggaggtatgtagaaaaccccagc
gccatggcctgttacaacgaactgctccagatggagtttggattggtgcgcccacagctg
aaactcagggcttgtaactcaatgttcactgcattagagaaaagtcaagaagcaattgaa
attacaagtgaagaccacattgtacagtatgcaaatccagcatttgaaacaacaatgggc
tatgagtcaggtgaattaatagggaaggatttagcagaagtgcctgtaaatgaaaaaaag
gctgatttgctcgatactataaattcatgcatcaggataggcaaggaatggcaaggaatt
tgctctgccaaagagaaaaacggagataatgtacaacaaaatgtgaagatactacctgtc
attggacagggaggaaaaattagacactatgtgtccattgtcagagcgtgcaatggcaac
aataaggctacgaaaatagctgaatgtgttcagtctgacactcatacagataatcagtca
ggcaaacataacgacaggagaaaaagctcactagatgtcagaactgctgcctctcgaaca
agcaaagtttccagccagagacgacgctcctccatggcccggatacattccatgaagatc
gaggcgcccatcaccaaggcaatcaatatcatcagtgctgcccaggaaagcagtcccatg
cctgtgacagaagccttagatcgtgtgctggaaattctaagaaccactgaattatattca
ccacaatttgatgctaaggatgatgatcctcatgccattgaccttgttgggggcttaatg
tctgatgtttttcgaagaccagccaggaatgagtatgttctttcaacaaaaaaccttcaa
caggtttccagcagtgtaatcacccccacctcccttcacgacatcccatcacagataact
caggccctggaaaatgaggaatcctgggactttgatatttttgaactggaggctgccact
cataaaaggcctttgatttatcttggtctcaaaatatttgctcgctttggagtctgtgaa
gtcttaaaatgctctgagacaacgctgagatcgtggatgcaaattatcgaagccaattat
catgcttctaacccctaccacaattctacacattctgccgatgtgcttcacgccactgcc
tattttctctgcaaagagaggataaagcaaactttagatccacttgatgaggtcactacc
ctcattgcagccactgtccatgacctggaccaccccgggagaaccaactccttcctgtgc
aatgctgggagcgagctggccattctgtataacgacactgctgtgctcgagagacaccac
gcggccttggccttccagctgaccactggtgatgataaatgcaacatctttaaaaacatg
gagaggaatgactaccggacgctgcgccagagtattatcgacatggtcttagccacagaa
atgacaaagcactttgagcacgtcaacaaatttgtcaacagcatcaacaagcccttggca
gcattagaggaagatggggaaactgataaaaatcaagaagccataatcactatgcccaga
actccagacaaccgctgtttgatcaaacgaatgctgattaagtgtgctgatgtgtccaat
ccctgccgacccctggagcagtgcattgagtgggccgcacgtatctcagaagaatatttt
tctcagactgatgaagagaagcgacaggacttgcctgtggtgatgccagtttttgacaga
aatacctgcagcatccccaaatcccaaatctctttcattgactacttcatcacagacatg
tttgctgcttgggacgcctttgtagacctgcctgagttaatgcagcatcttgacaacaat
tttaaatactggaagggactggacgaaatgaagctgcggagcctccgcccacctcctgaa
tag
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