Balaenoptera musculus (blue whale): 118892841
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Entry
118892841 CDS
T09887
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus04217
Necroptosis
bmus04380
Osteoclast differentiation
bmus04620
Toll-like receptor signaling pathway
bmus04621
NOD-like receptor signaling pathway
bmus04630
JAK-STAT signaling pathway
bmus04658
Th1 and Th2 cell differentiation
bmus04659
Th17 cell differentiation
bmus05145
Toxoplasmosis
bmus05160
Hepatitis C
bmus05161
Hepatitis B
bmus05162
Measles
bmus05164
Influenza A
bmus05165
Human papillomavirus infection
bmus05167
Kaposi sarcoma-associated herpesvirus infection
bmus05168
Herpes simplex virus 1 infection
bmus05169
Epstein-Barr virus infection
bmus05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118892841 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
118892841 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
118892841 (TYK2)
04621 NOD-like receptor signaling pathway
118892841 (TYK2)
04658 Th1 and Th2 cell differentiation
118892841 (TYK2)
04659 Th17 cell differentiation
118892841 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
118892841 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
118892841 (TYK2)
05160 Hepatitis C
118892841 (TYK2)
05171 Coronavirus disease - COVID-19
118892841 (TYK2)
05164 Influenza A
118892841 (TYK2)
05162 Measles
118892841 (TYK2)
05168 Herpes simplex virus 1 infection
118892841 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
118892841 (TYK2)
05169 Epstein-Barr virus infection
118892841 (TYK2)
05165 Human papillomavirus infection
118892841 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
118892841 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bmus01001
]
118892841 (TYK2)
Enzymes [BR:
bmus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118892841 (TYK2)
Protein kinases [BR:
bmus01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118892841 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
118892841
NCBI-ProteinID:
XP_036703716
UniProt:
A0A8B8X2J4
LinkDB
All DBs
Position
3:164023779..164046885
Genome browser
AA seq
1197 aa
AA seq
DB search
MPGKPAVKSMPLCQWGATTRGRKPDGDGAQPMATRGGLKVLLHWAGPGGGEPWVTFSEAT
LTAEEVCIHIAHKVGITPPCFNLFALFDVQAQVWLPPNHVLDMSRDSSLMLHFRMRFYFR
NWHGMHPQEPAVYRCGPPGSEPSSERAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWEL
SSEEEIHHFQNESLGMAFLHLCHLALCHGVPLEKVAKKTSFKDCIPRSFRQQIRQHNALT
RLRLRSIFRKFLRAFQPGCLSRQVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEP
CYIRVGGQAPPDPGPESAAGPPTHEVLVSGTDGIRWRLVQAEGPSDGGGGGGRRMPHAGP
SGKKAKAQEVGNQPVDRPQEAPWAYFCDFQDITHVVLKERRVSIHCQDNKCLDLTLPSRA
AALSLVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLQPGDGLY
LIHWSTSHLNRLILTVAQRDQARGVKGLHLRKFPIELQAGTVALEGWDRSFPSVRELRVA
LQGCSLRAGDDCFSLRHCCLPRPGEISNLIVTRGPRASSRPLNLSHLSFHRVRQEDITQL
SHLGQGTRTNVYEGLLRVGGGGPEEDKVDGGEPPMPGAGCEQELRVVLKVLDPSHHDIAL
AFYETASLMSQVSHVHLVFVHGIYVHGSENIMVTEYVEHGPLDVWLRRERGHVPLAWKLA
VAQQLASALSYLEDKSLVHSNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERV
ERIPWTAPECLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKL
PEPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQTLPDLADVLSVNPDSPASDPT
VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQLRTGWRREIEI
LRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFSQQICEG
MAYLHAQHYVHRDLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAP
ECLKECKFYYASDVWSFGVTMYELLTYCDSTQSPPSKFIELIGLTQGQMTVLRLTELLER
GERLPQPEKCPCEIYCLMKNCWKAEASFRPTFQNLIPILKTVHEKYQGQPPSVFSVC
NT seq
3594 nt
NT seq
+upstream
nt +downstream
nt
atgcccgggaagccagctgtcaagagcatgcctctgtgccaatggggggccaccacccgg
ggcagaaagcccgatggggatggagctcagcccatggccaccagaggaggcctgaaggtg
cttctgcactgggccggccccggtggcggggagccctgggtcaccttcagcgaggccaca
ctgactgcggaggaggtctgcatccacattgcacacaaagtcggcatcactccaccctgc
ttcaatctttttgccctcttcgatgtccaggcccaggtctggctgcctccaaaccacgtc
ctggatatgtccagagactcgagcctgatgctgcacttccgcatgaggttttatttccgg
aactggcatggcatgcacccccaggagccggctgtgtaccgctgcggtcccccggggtcc
gagccttcctcagaacgggcagagcagggggtgcaactcctggaccctgcctcctttgag
tacctctttgagcagggcaagcatgagtttgtaaatgacgtggcatcgctgtgggagctg
tcaagcgaggaggagatccaccactttcagaacgagagcctgggcatggcctttctgcac
ctctgccacctcgctctctgccatggtgtcccccttgagaaggtggccaagaagacaagc
ttcaaggactgcatcccacgctccttccggcagcagatccggcagcacaacgctctgacg
cggctgcgcctgcggagcatcttccgcaagttcctgcgggccttccagccgggctgcctc
tcgcggcaggttgtcatggtgaagtacctggccacactcgagcggctggcgccccgcttc
ggcacagagcgcgtgcccgtgtgccacctagagctactggcccaggccgagggggagccc
tgctacatccgggttggcggacaggcccctcccgaccccgggcccgagtctgccgccgga
ccccccacccacgaggtgctggtgtcgggcactgacggcatccggtggcggctggtgcag
gcagagggtcccagtgatggtggtggtggtggcggcagaaggatgccccatgctggccca
tctgggaagaaagccaaggcccaggaggtgggcaaccagcccgtggacaggcctcaggag
gccccatgggcctacttctgcgacttccaggacatcacccacgtggtgctgaaagaacgc
cgcgtcagcattcattgtcaggacaacaagtgcctggatttgaccctgccttcccgggct
gcggcactgtccttggtgtcactggtggacggctacttccgcctgacggccgactcgagc
cactacctatgccatgaggtggctcctccacggctggtgatgagtatccaggacggtatc
cacggacccctgctggagccatttgtgctggccaagctgcagcccggggatggcctctac
ctcatccactggagcaccagccacctcaaccgcctcatcctcacggtggcccagcgcgac
caggcacgtggcgtgaagggcttgcacctacggaagttccccatcgagctgcaggctggg
actgtcgcgctggagggctgggaccggtccttccccagcgtgcgcgagctgcgggttgcc
ctgcagggctgctccctgcgggccggcgacgactgcttttccctgcgccactgctgcctg
ccacggccaggagagatctccaacctcatcgtcacgcggggacctcgggccagcagcagg
ccactcaacctcagccatctcagcttccaccgggtccgccaggaagacatcacccagctg
tcccacttgggccagggcacgaggaccaacgtgtatgagggcctcttgcgagtggggggc
ggaggccccgaggaggacaaggtggatggcggggaaccccccatgcccggggcgggctgt
gaacaggagctgcgagtggtgctcaaggtgctagatcccagtcaccatgacatcgccctg
gccttctacgagacagccagcctcatgagccaggtctcccacgtgcacctggtcttcgtg
cacggcatctacgtgcacggctccgagaacatcatggtgacggagtacgtggagcacggg
cccctggacgtgtggctgcggcgggagcggggccacgtgcccctggcctggaagctggca
gtggcccagcagctggccagcgccctcagctacctggaagacaagagcctggttcacagc
aacgtgtgtggccggaacatcctgctggcacggctggggctggcggagggcaccagcccc
ttcatcaagctgagtgaccccggcgtgggcctgagcgccctctccagggaggaacgggtg
gagcggatcccctggacagcccctgagtgcctgtccggtggagccaacagcctaagcact
gcagccgacaagtggggctttggtgccaccctcctggagatctgcttcgatggggaggcc
cccctgcagggccgcagcccctccgagaaagagcgcttctaccagaagcagcacaagctg
cctgagccctcgtgcccagagctggccacactcaccagccagtgcctgacctatgagcca
gcccagcggccgtccttccgcaccatcctgcgtgacctcactcagctgcagccccaaact
cttccagatctcgctgatgtcttgtctgtgaacccggactcaccggcgtcagatcctacg
gttttccacaagcgctatttgaaaaagatccgggatctgggtgagggtcacttcggaaag
gtcagcctgtactgctatgatccaaccaatgacggcactggtgagatggtggccgtgaag
gccctcaaggcagactgcggtccccagctccgtacaggctggaggcgagagatcgaaatc
ttgcgcacactctaccacgagcacattgtcaagtacaagggctgctgcgaggaccaaggc
gagaagtcggtacagctggtcatggagtacgtgcccctgggcagcctccgagactacttg
ccccggcacaatgtcgggctggcccagctgctgctcttctcccagcagatctgcgagggt
atggcctacctgcacgcgcagcactacgtgcaccgagacctggccgcacgcaacgtgctg
ctggacaacaacaggctggtcaagattggggacttcggcctcgccaaggccgtgcccgaa
ggccacgagtactactgcgtgcgcgaggatggggacagtcccgtgttctggtatgccccg
gagtgcctgaaggagtgtaagttctactatgcatccgacgtctggtcctttggggtcacc
atgtatgagctgctgacctactgtgactccacccagagccccccctcgaaattcatcgag
ctcataggcctcacccaggggcagatgacagtgctgaggctcactgagctgctggaacga
ggggagaggctgccacagccagagaaatgtccctgtgagatctattgccttatgaagaac
tgctggaaagcagaggcctcattccgcccgaccttccagaacctcatacccatcctcaaa
acggtccacgagaaataccaaggccagccaccctcagtgttcagtgtctgctga
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integrated database retrieval system
