Balaenoptera musculus (blue whale): 118894582
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Entry
118894582 CDS
T09887
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00230
Purine metabolism
bmus00670
One carbon pool by folate
bmus01100
Metabolic pathways
bmus01523
Antifolate resistance
Module
bmus_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118894582 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118894582 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118894582 (GART)
Enzymes [BR:
bmus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
118894582 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
118894582 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
118894582 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
LUD_dom
RimK
ATP-grasp_5
DUF3104
SNF5
Motif
Other DBs
NCBI-GeneID:
118894582
NCBI-ProteinID:
XP_036706803
UniProt:
A0A8B8XAW6
LinkDB
All DBs
Position
4:complement(133404910..133434985)
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AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSNHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIAGSLASAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKAEEACRFIMSADFPALVVKASGLAAGKGVVVAKSKEEACKAVQEIMQDKAF
GEAGETTVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQQEGVPYAGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLHGLLCTSLPVWLDNRTAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEGAKKGLAAIKFEGAIYRND
IGYRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFNDPLLACGTDGVGTKLKIAQQCHKHETIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDPSTTEAVVAGIAKACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGGQALGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLTQQILQDIQQHKEEAWVIGRVVACPEGSPRVKVKH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAHIVVV
ISNKAAVTGLDKAERAGIPTRVINHKLYKNRVAFDTTVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGTVRLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagggaacatactctggcctggaaa
cttgcacagtctaatcatgtcaagcaagtgttagtcaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcgaacactgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgctgggagcctggcgtctgcaggagtgcggtgctttggcccgacagcggaagca
gctcagttagagtccagcaagagatttgccaaagagttcatggaccgacatggaatccca
actgcacagtggagagccttcaccaaagctgaagaagcctgccgcttcattatgagtgca
gacttccccgctttggttgtgaaggccagtggtcttgcagctggaaaaggggtagttgtc
gcaaagagcaaagaagaggcctgcaaagctgtacaggagattatgcaggataaagctttt
ggagaagctggagaaacaactgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaagactgtggcccccatgcccccagcacaggaccataagcga
ttgctggagggagatcagggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttgctaaaaattaaaaatactattcttcagaggacagtggat
ggcatgcagcaggagggtgtgccatatgcaggtatcctctatgctggtataatgctgacc
aaggacggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgacctttatgaagtgattcagtctaccttacatggcctg
ctctgcacatctctgcctgtttggcttgacaaccgcactgccgtaactgtggtcatggca
agtaaaggctatccaggagactacaccaagggtgtagagataacagggtttcctgaggct
caagctttaggactagaggtgttccaagcaggcactgccctaaaagatggcaaagtggtg
actaacgggggtagggtccttacagtaacggccatccgggaaaatctcatctcagccctt
gaaggagccaagaaaggactagctgctataaagtttgagggagccatttataggaacgac
attggctatcgtgccatagctttcctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaagcctttagcaaaagcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagccggtttcaacgatcctcttctggcctgtggaacagatggcgttggaactaaactg
aagattgcccagcagtgccataaacatgaaaccattggtcaagatttggttgcgatgtgt
gtaaatgatattctggcacaaggagcggagcccctctttttcctcgactacttttcctgt
ggaaaacttgaccccagtacgactgaagctgttgttgctggaatcgctaaagcttgtaaa
aaagccggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatgtaccctcct
ggagagtatgatctagccggttttgccgttggtgcaatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggagatgctgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcgaaatcttcccttcagtactcctct
ccagcacctgatggctgtggtggccaggccttaggtgacttacttctaactccaaccaga
atctacagccattcactgttacctgtcctgcgttcaggacatgttaaggcctttgcacat
attaccggtggaggattgctagaaaacatccccagagtcctacctcagaaatttggggtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaggaagga
cacctctctgaagaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaaaggatctgacacagcagattctgcaggatattcagcagcacaaggaagaagcc
tgggtgatcggcagagtggttgcatgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcaaataaatggatcagtattggagaatggcaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagtagctgtcttaatatctgggacaggatcaaac
ctccaagctctcatagacagtactagggagccaagcagctccgcacacattgttgttgtg
atctccaacaaagctgcagtgactggcttagataaagcagaaagagccggaattcccacc
agagtaattaatcataaattatataaaaatcgtgtagcatttgacactacagtagaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggatgccggggtcactgtcactggg
tgcaccgtgcactttgtagctgaagacgtagatgctggacaaattattttacaagaagct
gttccggtgaagaggggtgacactgttgaaactctatctgaaagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggaactgtacggcttggagaa
aatggcaagatctgttgggtcaaagaggaatga
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