Balaenoptera musculus (blue whale): 118896585
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Entry
118896585 CDS
T09887
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
118896585 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
bmus03021
]
118896585 (SETX)
Enzymes [BR:
bmus01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
118896585 (SETX)
5.6.2.5 RNA 5'-3' helicase
118896585 (SETX)
Transcription machinery [BR:
bmus03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
118896585 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
UvrD-helicase
AAA_19
AAA_30
AAA_22
Viral_helicase1
nSTAND3
ResIII
AAA_16
SLFN-g3_helicase
NAT10_TcmA_helicase
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
118896585
NCBI-ProteinID:
XP_036710443
UniProt:
A0A8B8XKY1
LinkDB
All DBs
Position
6:complement(112092475..112175854)
Genome browser
AA seq
2678 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLQRYASETHSSEFQTADEDLCYCLECVAEYHKARDELPFLHKV
LWELETSRLINHFEKAMKAEIGDDDELYIIDSNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTANYKNYWLG
ICMLLTILEEQAMDSLLLGSNKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSVRSKLEAESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDTVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCAKGTTMITSLSLHSVPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNTKFKVP
QCSTSVDLTPPASYNKEESEQTGKKSKKDRHCLENSSPTFSKEPMKADACQVQESIFSKA
NNAIEEDNEQTYIKDLKLEDHFSAELCLKPSSKRLVNERARGQVKISTGKHKSVKENSSY
TPQNCTSRNGPEKVFDRGIITSTRLLTDSSSDSLEKVSTSNEDFSLKDDALGKTSKAKTK
AHKDEICAKLSHVIKKQHRKSITLEENLTVSSIESFYSKKDTGGQKGYGFIHNPSLGPNG
ILDDKNGEQKSENSLLLKKKQVKEEELGIFSTPEISCQILECHVDNKDLVSFTEMTNIFV
EKTPPFKDPVTGLESRDTEISKSTVQFSSNLREQALSISHNSDTLTDSQIDRDLRELSLI
AQASVTKFPSDSAKKKSLSQLQRKVKDDRRRFTANKNSVRETCCGQVIIISDSDEDDEND
DERIVGFKKHIRQDKTCIEKDCPEQHTSIANTNVEQKVKEENTRSLLQFEESDSQFFEFE
SPCEVFSVWQDQKPDNKNSVRENEENSCLTHITNDGGYDTDYVPEEVIKKAAEGIEEHAE
PHSSSISVEKFCEIEVKKPKRKRYKKAAMAEDPVRPSSPVKSEDQSDILNERDVTENDFK
SIDIRTTTPSSSIQRTTTVSLKRSPPKLRTYSKPVRRVSLSKTPKKTHSDTKTGQSKSLN
YLSCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLECLAQLRDHGKTVG
VVDTRKKTKLISPQTLSVKNNKKLLTSQDLQLRRQRRPRSQQNRQGCFDYQSTDTARAGP
HAAQNSDKFVPESDTSDYSYKRGAEVTAKSKEKQLIKCVSSETEPTKAKYVSQVADDTCL
LNQCNSVVLNGEIPTNEIVVSTSGDPLGGGDLTVHHLDVAALKEGEPESSSDIEEDNIFL
TQCDPEDMDLCSQMEKENDKLIEVVHGKDTVQVEEDSVSRPQLESLSSTKCKYKDCVETL
KNQGEYCSKHSEAKAADEDIFRKPGLPLSASKPSRPSTAKIFSSSSTSRIAGLSKSLENT
SALLPTLKNKSSGVQSVLKVPQPASPVSQKPVAEVKGLCNVLRSHTPNNSNRQGYKVPFG
ENRSFLATSPVNILLSAQSISDTFVKEILKWKYEMFVNFDHCGPPSTLCQSIARHVPVRF
QDCGDYFNVFFPLMILNTFETVAQEWTSSPNKEKFHQLHLRKFPTDYKKYWEFVVYLEEC
ELAKQLHPKENDLVFLVPERLNGEKKDIERHRMQDPHEYYCGYVHKFRRTSVMRNGKSEC
SLSIQTQHNLPVNLNEFVKCLVISSLVTTQRKLKAMSLLSGRSQLARAVLNPNPMDFCTK
DLLTTASERIIAYLKDFNEDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSKTIVGLL
YRLLTERRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCG
DINLVRLGPEKSINTEVLKFSLDSQVNHRMKKDLPSHIQEMHRRKEFLDHQLDELSRQRA
LCRGGRELQRQELDEKIAKVSKERQELASKIKEVQGRPQKTQNIIILESHIICCTLSTSG
GLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCSKLILVGDPKQLPPTVISVK
AQDYGYDQSMMARFYKLLEENVEHNVIGRLPVLQLTIQYRMHPDICLFPSNYVYNKSLKT
NRLTETIRCSSEWPFQPYLVFDVGDGSEKRDNDSYVNVQEIKLVMEIIKLIKDKRKDVTF
RNIGIITHYKAQKMMIQKDLDKEFDGKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSI
GFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTWDKNYRHDA
VKILKLKPILQRSLTHPPAVAPEVSTPQGGVPSNKLDSEFAKMSFASSPYHSPSDSKEAT
VTVTAKDPERPPIQDRLRDPRLLRRMGLGCEAKGKCLSELQPSSPQYPGATPPLGEPGFP
GSHQDPTSIGQQPPAKGAAVNRHSPHAQCDAPAASTNASASKRAQEGGALSHRRETRAFT
EGDQERRGSLSHHTKRNSGWDERGLEEEDSSLKKRRLL
NT seq
8037 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggtatttccaccattgacttcctgcaacgc
tatgcatctgagacccactccagtgaatttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtggctgaataccacaaagcaagggacgaattgccattcttacataaggtt
ttatgggaattagaaacctcacgtctcataaatcactttgaaaaggccatgaaagcagaa
attggagatgatgacgagttatatataatagacagcaatggagaggcacagctgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatttgcttttacatgaacgtgttaatgaattatgcgttgaagcactttgccggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccagggatatatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttgggaaaa
gtagacagagatgattattatgacttacaggaggttttgacttgcctttttaaagttatt
gagttggggcttttagaaagtccagacatttatacttcttctgtccttgagaagggtaaa
ctgattcttctgccttcacacatgtatgatactgccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
aacaaacagaatgattttatgcaatcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac
aacgtgagctacaataaagagatccagaatatacggaacagctctgtgaggagcaagtta
gaagcggagtcatatttggatgatatggtgacttgcagccagattgtatacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggagacgctagctaacgtgcttcagtcagatatcggtcaagac
atgcgtgttcataacagcacgtttctgtggttcatccctttcgtgcagtccctcatggat
cttaaggatctgggtgtggcttatatagtggaggttattcatcatctgcattccgaagtc
aaagacgtcctcaaccagacagacgccgtgtgtgacacagtcactgagtttttccttctc
attttggtgtcagtgattgaacttcatagaaataaaaagtgtttgcatttgctgtgggtt
agttcccagcagtgggtggaagccgtcgtaaaatgtgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcgtctggaaactgtgccaaaggcacaacaatgataacatct
ctgtcattgcattcagtgccatctaactctgtacaacttgcttgtgtgcagctgatcaga
agtctccttaaagaaggctatcagcttgggcagcagactctttgtaagcgattctgggat
aagctcaacttattcctgcgaggaaatttatctttaggttggcagttgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacacaaaattcaaagtacct
caatgtagcacttctgtggatctgactcctcctgcatcttataataaagaagaaagtgaa
caaacagggaagaagtctaaaaaagacagacactgtctggaaaactccagcccaacattc
tctaaagaaccaatgaaagctgatgcatgtcaagtgcaagagagtattttcagcaaagca
aataatgccatagaagaggataacgagcaaacttatataaaagatttgaaactcgaagac
catttctcagctgagttgtgcttgaagccgagtagtaaaaggcttgttaatgaaagagct
cgaggccaagttaaaataagtacagggaaacataagtctgtaaaagagaattcctcatat
accccacagaattgtacgtcaagaaatggtccagaaaaggtatttgacagaggaataata
acatcaacacgtttgttgactgattctagcagtgactctctggaaaaggtgtccacatcc
aatgaggatttctctttaaaggatgatgctcttggcaaaacctcaaaagcaaaaactaag
gcacataaagatgaaatctgtgctaagttatcacatgtaataaaaaagcagcacaggaaa
agtatcactttagaggaaaacctgactgtatctagcatcgaaagtttctattcaaagaaa
gatacaggaggtcagaaaggatatggcttcatacacaatccctctttaggccctaatggt
attctggatgataaaaatggagaacaaaaatctgaaaacagtttattgctgaaaaagaaa
caagtaaaggaagaagagttaggcattttctctacccctgaaatcagttgtcaaatactg
gaatgtcatgttgataataaagatttggtctcatttacagaaatgaccaatatttttgtg
gagaaaacacctccctttaaagatcctgtgactggacttgaatcaagagatacggaaatt
agcaagagtaccgttcagttttcttctaatttaagagaacaggcccttagcatcagtcat
aattctgacaccttaacagattctcagatagacagagacctccgcgaattatctttaata
gctcaagccagtgttactaagttcccatcagattcagctaaaaaaaaaagtctatcccag
ctacaaagaaaagttaaagatgatagaagacgtttcacagccaacaaaaatagtgtcagg
gaaacctgctgtggacaggttattattatttcagattctgatgaagatgatgaaaatgat
gatgaaagaattgtgggttttaagaaacacattagacaggataaaacatgcattgagaaa
gactgtccagagcagcatacttcaatagctaacacaaatgtggaacagaaggtaaaggaa
gaaaatacaaggtcccttttgcagtttgaggaatctgattctcagttttttgagtttgaa
agtccatgtgaagtgttttcagtttggcaagatcagaaaccagacaacaagaattcagtt
cgagagaatgaagaaaattcgtgcttgactcatatcacaaatgatgggggttatgataca
gattatgtacctgaagaggtcattaaaaaagcagcagagggcattgaggaacacgcagaa
ccacacagtagtagtatttctgttgagaaattttgtgaaattgaagtgaagaaacccaag
agaaaacgatacaagaaagctgctatggctgaagatcctgtaaggccttcatctcctgtc
aaaagtgaggaccagtctgatattcttaatgagagagatgtgactgaaaatgattttaaa
agtatagacataaggactacaactcccagttcaagcattcagagaaccactactgtttcc
ctgaagaggtctccaccaaagcttcgcacttattccaaacctgttaggagagtgtcactt
tctaaaactcctaaaaaaacacattcggataccaaaacaggacagagtaaaagtttaaat
tacctaagttgtagaacaactcctgctatagtgccaccaaagaaatttcgccagtgtcct
gaaccaacttcaacggttgagaaacttggtctgaaaaaggctcctcgtagggcatttgag
ttgtcccagcgatctttggagtgtttagctcagttacgtgaccatggcaaaactgttgga
gtagttgatacccggaaaaagactaagttaatttctcctcagactctctctgtcaaaaat
aataagaaactgctgacgagtcaagaccttcagttgcgaaggcagaggagacccagatca
caacaaaacagacaaggatgttttgattatcaaagtacagatacagcacgagccgggcca
catgcagcacagaattctgacaaatttgtgccagaatcagatacatcagattatagttat
aaaagaggagctgaggtaactgctaaaagtaaggaaaaacagttaataaaatgtgtgtct
tctgaaacagaacccacgaaagcaaaatatgtttctcaggtagctgatgacacttgtctt
ttgaaccagtgtaattctgtagtgttaaatggagaaataccaacaaatgaaatagttgtt
tctacctcaggggaccctttaggtggaggtgacctaacagtacatcatttagatgtggca
gctttgaaagagggagagcctgaatccagcagtgacatagaggaagataatatattttta
acacaatgtgatcctgaagatatggatttatgttcacaaatggagaaagagaatgataaa
ctcattgaagtagttcatggaaaagatacagtccaggtagaagaagattctgtgagtcgg
cctcagttggaatctttgagtagcacaaaatgtaagtacaaagattgtgttgaaacactg
aaaaaccagggtgaatactgttcaaaacactctgaagctaaagcagcagatgaagatata
tttcgtaaacctggcttgcctctctctgcatctaaaccttcgagaccttccactgctaag
atttttagctccagtagtacttcacgaattgctggtctttccaagtctttggaaaatacg
tcagcgctcctaccaactctgaaaaataagtcaagtggggtacaatctgttttgaaagta
ccacagccagcctctccggtgtctcagaagccagtggctgaagtgaagggtttgtgcaac
gttctccgttctcatactccaaataattccaacaggcaaggctacaaagttccatttggt
gaaaacagatctttcttggctacctctccagtaaacattctcttgtcagcacagtccatc
tctgacaccttcgttaaagagatcttaaaatggaaatacgaaatgtttgtgaactttgat
cattgcggacccccgtcaactctttgtcagtccatcgcaagacatgtgcctgtgagattt
caagattgtggagattattttaatgtgtttttccctttgatgatactgaatacttttgaa
acagtggcacaggaatggaccagctctccaaacaaagagaaattccatcagttgcattta
cgaaaatttcctactgattataaaaaatactgggagtttgtggtttatcttgaggaatgt
gaactagctaaacagcttcatccaaaggaaaatgatttggtgtttttggttcctgaaaga
ctaaatggagagaagaaggatatagagagacatcgcatgcaagatccccatgaatattat
tgtggttatgttcataaattccgccgcacttcagtcatgcgtaatgggaaatcggagtgt
tccctttccatccagacgcaacataatttaccagtcaatttaaatgaattcgtgaaatgt
cttgtaatcagctctctggtgactacacaaaggaagttgaaagccatgtctttgctgagt
ggtcggagccaactggccagagccgttctgaatccaaaccccatggacttctgtacaaaa
gatttactaactacagcatctgagagaattattgcctacctaaaagatttcaatgaagac
caaaagaaagcgatagaaactgcatatgccatggtgaaacactccccagcagttgccaag
atctgtctgattcatggaccacccgggacaggaaaatcaaaaaccattgtgggcctcctg
taccgcctactgacagagaggagggggcattcagatgagaactccaatgccaaaatcaaa
caaaaccgtgtccttgtgtgtgcaccttccaatgcagctgttgatgaacttatgaaaaaa
attatccttgaattcaaagagaagtgtaaagacaagaagaatcctttgggaaactgtgga
gatataaatttagtacgtctaggtccagaaaagtctattaatactgaggtcctaaaattc
agtttggacagccaagttaaccacagaatgaaaaaagacttaccttctcatattcaggag
atgcatagaagaaaggaatttctggatcatcaactagatgaactttcccgccagcgtgct
ttatgccgaggtggaagggagctacagaggcaagaattagatgaaaaaattgccaaagtt
tcaaaagaaaggcaggagcttgcttctaaaattaaagaggttcaaggacgcccacaaaag
acacagaacatcatcatcttagagtcccacatcatctgctgcacactgagcacgagtggt
ggtttgctgcttgaggctgctttccgtgggcaagggggtgtcccctttagttgcgtcatt
gttgatgaggccgggcagtcttgtgaagttgaaactcttactccgctcatccatcgctgc
agcaagctcatcctcgtaggggaccctaagcagctccctcccacggtcatctctgtgaag
gcccaggattatggctatgaccagtcgatgatggcccgcttctacaaacttctggaagag
aacgtggagcacaacgtgattggcaggctgcctgtcttacagctcaccattcagtacagg
atgcacccagacatatgtctcttcccttctaattacgtttataacaagagcttgaaaaca
aatagattgacagagaccattcggtgttcatctgaatggccatttcagccctacctcgtg
tttgatgttggagatggttcagaaaagcgggataatgactcatatgtaaatgttcaggaa
ataaaactggtaatggaaataattaaacttataaaagacaaaagaaaggatgttactttc
cgaaacattggcataataacccattacaaggctcagaagatgatgattcagaaggatttg
gacaaagagtttgatggaaaagggccagcagaagtagataccgtggatgccttccagggt
cgtcagaaagattgtgttattgttacatgtgtcagagcaaatgccatgcaaggctcaatt
gggtttctggcaagtttgcagagattgaatgtcaccatcacacgagccaagtacagcctc
ttcatcctgggacatttgaggaccctgatggaaaaccagcattggaatcacctgattcag
gatgcacagaagcgtggtgccattattaagacttgggacaaaaactatagacacgatgca
gtgaagattctgaaactcaagcccatactgcagagaagtctgactcaccctcctgctgtc
gccccagaggtgtccacaccccagggcggagtgcccagcaacaagctagacagtgaattt
gccaagatgtcctttgcttcttccccgtaccactcaccctctgactccaaagaagccact
gtcactgttactgcaaaggaccctgaaaggccacccattcaggaccggcttcgggaccca
cgactgcttaggaggatgggcttgggctgtgaagccaaagggaaatgcctcagtgagctg
cagccctcgagcccccagtaccccggagcaacgcctcccttgggagagccaggcttcccc
ggaagtcaccaggacccgaccagtatcgggcagcagccccccgccaagggagctgctgtg
aacaggcacagtcctcacgcgcagtgcgacgctccagctgctagtaccaatgcttccgcg
agtaaacgtgcccaggaagggggggcactcagccacaggagggagaccagggccttcact
gagggggatcaggagaggcgtggctctctgagccaccacacaaagaggaactcaggctgg
gacgagaggggactggaggaggaggacagtagcttaaagaagaggaggcttttatag
DBGET
integrated database retrieval system
