Balaenoptera musculus (blue whale): 118896827
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Entry
118896827 CDS
T09887
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00790
Folate biosynthesis
bmus01100
Metabolic pathways
bmus01240
Biosynthesis of cofactors
bmus01523
Antifolate resistance
bmus04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118896827 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
118896827 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118896827 (FPGS)
Enzymes [BR:
bmus01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
118896827 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
118896827
NCBI-ProteinID:
XP_036711158
UniProt:
A0A8B8XMX4
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Position
6:108434402..108453952
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AA seq
580 aa
AA seq
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MSRARCHLRAALFLAAVSSRGATTGVAARRVLSAWPAPQEPGMEYQDAVRTLNTLQTNAN
YLEQVKRQRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDDSSCVSMPGYFR
FLTLMAFHVFLQEKVDLAVMEVGIGGAYDCTNIVKKPVVCGVSSLGIDHTGLLGDTMEKI
AWQKGGIFKCGIPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPLLTLGLEG
EHQQSNAALALQLARCWLQQKGYQDTGELKASRPSLLGQLPLAPVFQPTSHMQHGLRDTE
WPGRTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHSRERPGGGSEVRVLLFNSTGDR
DSAALLKLLQPCQFDYTIFCPNLTEVSSTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHE
DQASPEAGGPAPLLLAPRPAHTHSTSSLVFSCISHALQWISQGRDPVFQPASPPRVLFAH
PVAGSGAIVLQEAATIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgctgccacctgcgcgcggctctcttcctggcagcggtttcttcgcgt
ggtgcaacaaccggggtcgcagcgaggcgagtattgagcgcgtggcctgcgccacaggag
cccggcatggagtatcaggatgctgtgcgcacactcaacaccctgcagaccaatgccaac
tacctggagcaggtgaagcgccagcggggtgacccccagacacaactggaagccatgaag
ttgtacttggcacggagtgggctgcaggtggaggacttggaccaactgaacatcatccac
atcactgggaccaaggggaagggctccacctgtgccttcactgaacgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgaatcaatgggcagcccataagccccgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatgacagcagctgtgtctccatgcctggctacttccgc
ttcctcacactcatggccttccatgtcttcctccaagagaaggtggacctggcagtgatg
gaagtgggcatcggcggggcttacgactgcaccaacatcgtcaagaagcctgtggtgtgt
ggggtctcctctcttggcatcgaccacactggccttctgggggacacgatggagaagatt
gcatggcagaaagggggcatttttaagtgtggcatccccgccttcaccgtgctccagcct
gacgggcccctggcagtgctgagggaccgcgctcagcagatctcatgtcccctctacctg
tgcccaccactagaagccctggaggaaggggggccactgctgaccctgggcctggagggg
gagcaccagcagtccaatgccgccttggccttgcagctggctcgctgctggctgcagcaa
aagggctaccaggatactggagagctgaaggcatccaggccaagcctcctggggcagctg
cccctggcacctgtgttccagcccacgtcccacatgcagcatgggcttcgggacacggag
tggccgggccggacgcagttgctgcggcgggggcccctcacttggtacctggacggcgcg
cacaccaccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcacagccga
gagaggccgggcggagggtctgaggtgcgtgtcttgctcttcaactctactggggaccgg
gattcggcggccctgctgaagctgctgcagccctgccagtttgactataccattttctgc
cctaacctgacagaggtgtcatccacggacaatgcagaccaacagaacttcacagtgacc
ctggaccaggtgctgctccgctgccttgcacaccagcaacactggagccgcctgcacgag
gaccaggccagcccggaggctggtgggcctgcacccctgctgctggcaccccgcccagcc
cacacccacagcaccagctccctcgtcttcagctgcatttcccacgccttgcagtggatc
agccaaggccgggaccctgtctttcagccagccagtcccccacgggtcctctttgcccac
cctgtggcaggcagtggggccatcgtcctccaggaggctgccaccatccacgtgctggtc
acaggcagcctgcacctggtgggcggcgtgctgaagctgctggagccctccctgtcccag
tag
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