KEGG   Balaenoptera musculus (blue whale): 118900502
Entry
118900502         CDS       T09887                                 
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus01521  EGFR tyrosine kinase inhibitor resistance
bmus04010  MAPK signaling pathway
bmus04014  Ras signaling pathway
bmus04015  Rap1 signaling pathway
bmus04020  Calcium signaling pathway
bmus04151  PI3K-Akt signaling pathway
bmus04360  Axon guidance
bmus04510  Focal adhesion
bmus04520  Adherens junction
bmus05100  Bacterial invasion of epithelial cells
bmus05144  Malaria
bmus05200  Pathways in cancer
bmus05202  Transcriptional misregulation in cancer
bmus05205  Proteoglycans in cancer
bmus05206  MicroRNAs in cancer
bmus05208  Chemical carcinogenesis - reactive oxygen species
bmus05211  Renal cell carcinoma
bmus05218  Melanoma
bmus05223  Non-small cell lung cancer
bmus05225  Hepatocellular carcinoma
bmus05226  Gastric cancer
bmus05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118900502 (MET)
   04014 Ras signaling pathway
    118900502 (MET)
   04015 Rap1 signaling pathway
    118900502 (MET)
   04020 Calcium signaling pathway
    118900502 (MET)
   04151 PI3K-Akt signaling pathway
    118900502 (MET)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118900502 (MET)
   04520 Adherens junction
    118900502 (MET)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    118900502 (MET)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118900502 (MET)
   05202 Transcriptional misregulation in cancer
    118900502 (MET)
   05206 MicroRNAs in cancer
    118900502 (MET)
   05205 Proteoglycans in cancer
    118900502 (MET)
   05208 Chemical carcinogenesis - reactive oxygen species
    118900502 (MET)
   05230 Central carbon metabolism in cancer
    118900502 (MET)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    118900502 (MET)
   05226 Gastric cancer
    118900502 (MET)
   05218 Melanoma
    118900502 (MET)
   05211 Renal cell carcinoma
    118900502 (MET)
   05223 Non-small cell lung cancer
    118900502 (MET)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    118900502 (MET)
  09174 Infectious disease: parasitic
   05144 Malaria
    118900502 (MET)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118900502 (MET)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bmus01001]
    118900502 (MET)
Enzymes [BR:bmus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     118900502 (MET)
Protein kinases [BR:bmus01001]
 Receptor tyrosine kinases (RTK)
  MET family
   118900502 (MET)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr TIG Pkinase Sema PSI Kinase-like Pkinase_fungal Linker_histone
Other DBs
NCBI-GeneID: 118900502
NCBI-ProteinID: XP_036718794
UniProt: A0A8C0CUB7
LinkDB
Position
9:complement(33913477..34041229)
AA seq 1382 aa
MKAPAVLAPGILVLLFTLVQKSNGECKEALVKSKMNVNMQYQLPNFTAETPIQNVVLHKH
HIYLGAINYLYVLNDKDLQKVAEYKTGPVLEHPDCFPCQNCSHKANLSGGVWKDNINMAL
LVDTYYDDQLISCGSVHRGTCQRHVLPPDNTANIQSEVHCMYSPQADEEPSQCPDCVVSA
LGTKVLLSEKDRFINFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGTQLAKQIGANLNDDILYGVFAQSKTDSVEPMNR
SAVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSLTPHVNF
RLDSHPVSPEAVVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPSFVQCG
WCHDKCVRLEECPGGTWTQETCLPTIYKVFPTSAPLEGGTTLTICGWDFGFKRNNKFDLK
KTKVLLGNESCTLTLSESTINMLKCTVGPAMNEHFNMSIVISNSRGTVHYSTFSYVDPII
KSISPSYGPKTGGTLLTLTGKHLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQSTPTE
FPIKLKIDLASREMNSFIYREDPIVYEIHPTKSFVSGGSTITGVGKNLNSVSILRMVINV
HEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPND
LLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPILTSGDSDISSPLLQNAVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVDGEG
DT
NT seq 4149 nt   +upstreamnt  +downstreamnt
atgaaggcccctgctgtgcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagcaatggggagtgtaaagaggcactagtaaagtccaagatgaatgtgaacatgcag
tatcagcttcctaacttcacagcagaaacacccattcagaatgtcgttttgcacaagcat
cacatttacctcggtgccattaactacctttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcctgtgctggaacacccagattgtttcccatgtcagaac
tgcagccacaaagccaatttatcaggtggcgtttggaaagataacatcaacatggctctg
cttgttgacacgtactatgatgaccaactcattagctgcggcagtgtccacagagggacc
tgccagcgacacgtccttccacctgacaatactgctaacatacagtcggaggttcattgc
atgtactctccacaggcagacgaagagcccagccagtgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctgctgtctgagaaggatcgattcatcaacttcttcgtgggcaat
accataaattcttcttaccttccagatcattcattgcattcgatatctgtgagaaggcta
aaggaaacgcaagatggttttaagtttttgacagaccaatcctatattgatgttctacct
gagttccgagattcctaccccattaagtatgtccacgcctttgaaagcaaccattttatt
tactttttgacggtccaacgggaaactctagatgctcagacttttcacacaagaataatc
aggttctgttcagtagactctggtttgcattcgtacatggaaatgcctctggagtgtatt
ctcacagaaaagagaagaaagagatccacaagggaggaagtgtttaatattctccaagct
gcgtatgtcagtaagcctgggacccagctcgctaagcaaataggtgccaacctgaatgat
gacattctctacggggtgtttgcacaaagcaagacagattctgtcgaaccaatgaatcgc
tctgctgtctgtgcgttccctgtcaaatatgtcaatgagttcttcaacaagatcgtcaac
aaaaacaatgtgagatgtctccagcatttttatggccccaaccacgaacactgcttcaat
aggacacttctgagaaattcatcaggctgtgaagtgcgcagtgatgaataccgaacggag
tttaccacagctttgcagcgcgttgacttattcatgggccagttcaaccaagtcctctta
acatctatatccacctttattaaaggagacctcaccatcgctaatcttggaacgtcagag
ggtcgattcatgcaggttgtggtttctcgatcaggatcattaaccccacatgtgaatttt
cgcctggattcccaccctgtgtctccagaagcagttgtggagcacccgctaaaccaaaat
ggctatacactcgttgtcactgggaagaagatcaccaagatcccgctgaatggcttgggc
tgtgaacatttccagtcctgcagtcagtgcctctccgccccttcctttgtgcagtgtggc
tggtgccatgataaatgtgtgcgattggaggaatgccctggtggaacatggactcaagag
acctgtctgcctacaatctacaaggttttcccaactagtgccccccttgaaggagggaca
actctgaccatatgtggctgggactttggattcaagaggaataataaatttgacttgaag
aaaaccaaagttctccttggaaatgagagctgcaccttgactttaagtgagagcacgata
aacatgttgaaatgcacagttggtcctgcaatgaatgaacatttcaatatgtccatagtt
atttcaaacagtcgagggaccgtacattatagtacattttcctatgtggatcctataata
aaaagtatttctccaagttatggtcctaaaactggtggcactttacttacattaactgga
aagcacctaaacagtggaaattctagacacatttcaattggtggaaaaacttgtacttta
aaaagtgtttcagatagtattctcgaatgttataccccagcccaaagcactccaactgag
tttcctattaaattgaaaattgacttagccagccgagagatgaacagcttcatttaccgg
gaagaccccattgtctatgaaatacatcccaccaaatctttcgttagtggtgggagcaca
ataacaggtgttggaaaaaacctgaattcagttagtatcctgaggatggtaataaatgtg
cacgaagcgggaaggaactttacagtggcatgtcagcatcgctctaattcggagataatc
tgctgtacaactccttcactacaacagctgaacctacaactccccctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtgctagaa
atcaagggaaacgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagaatatacactcacattctgaagccgttttatgtacggtccccaatgac
ctgctgaaattgaacagtgaactaaacatagagtggaagcaagcaatttcttcaaccgtc
cttggaaaagtgatagttcaaccagatcagaatttcacaggactgattgttggtgttgtc
tcaatatcaataatactcttattattacttgggctgttcctgtggctgaaaaagagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagggtacacactcctcat
ttggatcggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactacagagctacttttccagaagaccagtttcctaactcatctcagaatggg
tcatgcagacaagtgcagtatcctctgacagacctatcccccatcctaactagtggggac
tctgatatatccagtccattactgcaaaatgctgtccacattgacctcagtgctctaaat
ccagagctggtccaggcagttcagcatgtagtgattgggccaagcagcctgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtatatcatgggactttgttggac
aacgatgataagaaaattcactgtgctgtgaaatccttgaatagaatcactgacatagga
gaagtttcccaatttctgaccgagggaatcatcatgaaagattttagtcatcccaatgtt
ctctcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccgtac
atgaaacatggggatcttcgaaatttcattagaaatgagactcacaaccccactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtccacagagacttggctgcaagaaactgtatgctggatgaaaaattcactgtcaaa
gttgctgattttggccttgccagagacgtgtatgataaggaatactatagcgtacacaac
aaaacaggtgcaaaactgccggtgaagtggatggctttagaaagcctgcaaactcagaaa
tttaccaccaagtcagatgtgtggtcctttggcgtgctcctctgggaactgatgacaaga
ggagcaccaccttatcctgatgtcaacacctttgatatcacagtatatttgttgcaaggc
agaaggctcctacaacctgaatactgcccagatcccttgtatgaagtgatgctgaaatgc
tggcaccctaaagctgaactgcgcccatccttttctgaactggtctccaggatatcagcg
atattctctactttcattggggagcactatgtccacgtgaacgctacatacgtgaatgtc
aaatgtgtcgctccatatccttctctgttgtcatcacaagataatgttgatggcgagggg
gacacatga

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