KEGG   Balaenoptera musculus (blue whale): 118901763
Entry
118901763         CDS       T09887                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus01522  Endocrine resistance
bmus04010  MAPK signaling pathway
bmus04015  Rap1 signaling pathway
bmus04068  FoxO signaling pathway
bmus04071  Sphingolipid signaling pathway
bmus04114  Oocyte meiosis
bmus04148  Efferocytosis
bmus04218  Cellular senescence
bmus04261  Adrenergic signaling in cardiomyocytes
bmus04370  VEGF signaling pathway
bmus04380  Osteoclast differentiation
bmus04517  IgSF CAM signaling
bmus04550  Signaling pathways regulating pluripotency of stem cells
bmus04611  Platelet activation
bmus04613  Neutrophil extracellular trap formation
bmus04620  Toll-like receptor signaling pathway
bmus04621  NOD-like receptor signaling pathway
bmus04622  RIG-I-like receptor signaling pathway
bmus04625  C-type lectin receptor signaling pathway
bmus04657  IL-17 signaling pathway
bmus04658  Th1 and Th2 cell differentiation
bmus04659  Th17 cell differentiation
bmus04660  T cell receptor signaling pathway
bmus04664  Fc epsilon RI signaling pathway
bmus04668  TNF signaling pathway
bmus04670  Leukocyte transendothelial migration
bmus04714  Thermogenesis
bmus04722  Neurotrophin signaling pathway
bmus04723  Retrograde endocannabinoid signaling
bmus04728  Dopaminergic synapse
bmus04750  Inflammatory mediator regulation of TRP channels
bmus04912  GnRH signaling pathway
bmus04914  Progesterone-mediated oocyte maturation
bmus04917  Prolactin signaling pathway
bmus04926  Relaxin signaling pathway
bmus04932  Non-alcoholic fatty liver disease
bmus04933  AGE-RAGE signaling pathway in diabetic complications
bmus04935  Growth hormone synthesis, secretion and action
bmus04936  Alcoholic liver disease
bmus05014  Amyotrophic lateral sclerosis
bmus05020  Prion disease
bmus05022  Pathways of neurodegeneration - multiple diseases
bmus05132  Salmonella infection
bmus05133  Pertussis
bmus05135  Yersinia infection
bmus05140  Leishmaniasis
bmus05142  Chagas disease
bmus05145  Toxoplasmosis
bmus05152  Tuberculosis
bmus05161  Hepatitis B
bmus05163  Human cytomegalovirus infection
bmus05167  Kaposi sarcoma-associated herpesvirus infection
bmus05169  Epstein-Barr virus infection
bmus05170  Human immunodeficiency virus 1 infection
bmus05171  Coronavirus disease - COVID-19
bmus05205  Proteoglycans in cancer
bmus05208  Chemical carcinogenesis - reactive oxygen species
bmus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bmus05415  Diabetic cardiomyopathy
bmus05417  Lipid and atherosclerosis
bmus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118901763 (MAPK12)
   04015 Rap1 signaling pathway
    118901763 (MAPK12)
   04370 VEGF signaling pathway
    118901763 (MAPK12)
   04668 TNF signaling pathway
    118901763 (MAPK12)
   04068 FoxO signaling pathway
    118901763 (MAPK12)
   04071 Sphingolipid signaling pathway
    118901763 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    118901763 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118901763 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118901763 (MAPK12)
   04218 Cellular senescence
    118901763 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118901763 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118901763 (MAPK12)
   04613 Neutrophil extracellular trap formation
    118901763 (MAPK12)
   04620 Toll-like receptor signaling pathway
    118901763 (MAPK12)
   04621 NOD-like receptor signaling pathway
    118901763 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    118901763 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    118901763 (MAPK12)
   04660 T cell receptor signaling pathway
    118901763 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    118901763 (MAPK12)
   04659 Th17 cell differentiation
    118901763 (MAPK12)
   04657 IL-17 signaling pathway
    118901763 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    118901763 (MAPK12)
   04670 Leukocyte transendothelial migration
    118901763 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118901763 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    118901763 (MAPK12)
   04917 Prolactin signaling pathway
    118901763 (MAPK12)
   04926 Relaxin signaling pathway
    118901763 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    118901763 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118901763 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    118901763 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    118901763 (MAPK12)
   04722 Neurotrophin signaling pathway
    118901763 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118901763 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118901763 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    118901763 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118901763 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    118901763 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118901763 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118901763 (MAPK12)
   05161 Hepatitis B
    118901763 (MAPK12)
   05171 Coronavirus disease - COVID-19
    118901763 (MAPK12)
   05163 Human cytomegalovirus infection
    118901763 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118901763 (MAPK12)
   05169 Epstein-Barr virus infection
    118901763 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118901763 (MAPK12)
   05135 Yersinia infection
    118901763 (MAPK12)
   05133 Pertussis
    118901763 (MAPK12)
   05152 Tuberculosis
    118901763 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118901763 (MAPK12)
   05140 Leishmaniasis
    118901763 (MAPK12)
   05142 Chagas disease
    118901763 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118901763 (MAPK12)
   05020 Prion disease
    118901763 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    118901763 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118901763 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    118901763 (MAPK12)
   05415 Diabetic cardiomyopathy
    118901763 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118901763 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    118901763 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118901763 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118901763 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bmus01001]
    118901763 (MAPK12)
Enzymes [BR:bmus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118901763 (MAPK12)
Protein kinases [BR:bmus01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118901763 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like Haspin_kinase TAP42
Other DBs
NCBI-GeneID: 118901763
NCBI-ProteinID: XP_036721208
UniProt: A0A8B8YFP3
LinkDB
Position
10:complement(104293542..104302218)
AA seq 392 aa
MSSPQLARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPNETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPPEFVQRLQSAEAQNYMKGLPELQKKDFASILTNASPLAVNLLEKMLVLDAERRV
TAAKALTHPYFESLHDTEDEPKAQKYDESFDDVDRMLDEWKRFALAWRPRAPLFISEGSQ
HLLSLRLGSDACPAPGPPSAGALTSHAGTGPV
NT seq 1179 nt   +upstreamnt  +downstreamnt
atgagctctccgcagctcgcccgcaagggcttttaccgccaagaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctcgggcgcctatggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggtggccataaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccatgagaacgtaattgggctgctggatgtgttcacacccaatgagaccctggat
gatttcacagacttttacctggtgatgccgttcatgggcaccgacctggggaagctcatg
aagcacgagaagctgagtgaggaccggatccagttcctcgtctaccagatgctcaagggg
ctgaagtacatccacgctgctggcatcatccacagggacctgaagcctggcaacctggcc
gtgaacgaggactgtgagctgaagatcctggactttggcctggcccggcaggcagatagc
gagatgactggatacgtggtgacccggtggtaccgggcgcctgaggtcatcttgaattgg
atgcactacacacagacggtggacatctggtcagtgggctgcatcatggctgagatgatc
acagggaagacgctcttcaaaggcagcgaccacctagaccagctgaaggagatcatgaag
gtgacggggacgcctccccctgagtttgtgcagaggctgcagagtgccgaggctcagaac
tacatgaagggcctccctgagctacagaaaaaggattttgcctccatcctgaccaacgcg
agccctctggccgtgaacctcctggagaaaatgctggtgctggatgcggagcggcgggtg
acggcggccaaggcgctgacccacccctacttcgagtcgctgcacgacacagaggacgag
cccaaggcccaaaagtacgatgaatcctttgatgacgtggaccgcatgctggacgagtgg
aagcgctttgcattggcctggagaccaagggcccctctcttcatctctgagggctcccag
cacctgctcagcctgaggctgggctcggacgcctgcccagcccccgggcctccctctgct
ggggccctgacgtcccatgctggaacgggccctgtctag

DBGET integrated database retrieval system