Balaenoptera musculus (blue whale): 118905781
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Entry
118905781 CDS
T09887
Symbol
SRD5A2
Name
(RefSeq) LOW QUALITY PROTEIN: 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00140
Steroid hormone biosynthesis
bmus01100
Metabolic pathways
bmus05215
Prostate cancer
Module
bmus_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
118905781 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
118905781 (SRD5A2)
Enzymes [BR:
bmus01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
118905781 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
118905781
NCBI-ProteinID:
XP_036728474
UniProt:
A0A8B8Z314
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All DBs
Position
13:65145922..65204927
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AA seq
322 aa
AA seq
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MAISDREESQKLQHQRLMGEEQIFEGQLEGENSGRLWRGADARAKARIWAKGRAQDTKLA
RESLHPLSAWLLSEESPVLAGSATLAALGALVLCLAEPAGYGKYTESRMPVATRLSARAA
WFLQELPSFAVPAGILAGQPRSLFGQPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFL
FRGFVFCMGNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLFILGMGINIHSDYILRQLRK
PGEIIYRIPQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHH
RFYLKMFEDYPKSRKALIPVIF
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggctatttcggacagagaagagtcccagaagttgcagcatcagaggttgatgggtgaa
gaacaaatcttcgaagggcagttagaaggagagaacagtggcaggctgtggagaggggcg
gacgcgcgggcgaaggcgcgaatatgggctaaaggaagggcgcaggacacgaagttggct
cgcgaaagccttcatccactctccgcctggctgctttccgaagagagtccggtgctggca
ggcagcgccactttggccgccctgggggcactggttctgtgcctcgcggagcccgccggc
tacgggaagtacacggagagccggatgcccgtggctacccgcttgtccgcccgcgccgcc
tggttcctgcaggagctgccctccttcgcggtgcccgcggggatcctcgccgggcagccc
cgctctctcttcggccagcctgcgactgtgcttctgggcctcttctgcgcacattacttc
cacaggacatttgtttactcactgctcactagagggaggccgtttccagttgtattcctt
ttcagaggctttgtcttctgcatgggaaatggactcctccaaggctactatctggtttac
tgtgctgaataccctgctgagtggtacacagacatacggtttagcttgggtgtcttctta
tttattttgggaatgggaatcaacattcatagtgactatatattgcgccagctcaggaag
cctggagaaatcatctataggattccacaaggtggcttgttcacatacgtttctggagcc
aatttccttggcgagatcattgaatggatcggctatgccctggccacttggtccctccca
gcacttgcatttgcatttttctcactttgtttccttgggctgagagcttttcaccaccat
agattctacctcaagatgtttgaggactaccccaagtctcggaaagccctcattccagtc
atcttttaa
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