Balaenoptera musculus (blue whale): 118906231
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Entry
118906231 CDS
T09887
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus01521
EGFR tyrosine kinase inhibitor resistance
bmus01522
Endocrine resistance
bmus04010
MAPK signaling pathway
bmus04012
ErbB signaling pathway
bmus04014
Ras signaling pathway
bmus04062
Chemokine signaling pathway
bmus04068
FoxO signaling pathway
bmus04072
Phospholipase D signaling pathway
bmus04150
mTOR signaling pathway
bmus04151
PI3K-Akt signaling pathway
bmus04510
Focal adhesion
bmus04540
Gap junction
bmus04630
JAK-STAT signaling pathway
bmus04650
Natural killer cell mediated cytotoxicity
bmus04660
T cell receptor signaling pathway
bmus04662
B cell receptor signaling pathway
bmus04664
Fc epsilon RI signaling pathway
bmus04714
Thermogenesis
bmus04722
Neurotrophin signaling pathway
bmus04810
Regulation of actin cytoskeleton
bmus04910
Insulin signaling pathway
bmus04912
GnRH signaling pathway
bmus04915
Estrogen signaling pathway
bmus04917
Prolactin signaling pathway
bmus04926
Relaxin signaling pathway
bmus04935
Growth hormone synthesis, secretion and action
bmus05034
Alcoholism
bmus05160
Hepatitis C
bmus05161
Hepatitis B
bmus05163
Human cytomegalovirus infection
bmus05165
Human papillomavirus infection
bmus05200
Pathways in cancer
bmus05205
Proteoglycans in cancer
bmus05206
MicroRNAs in cancer
bmus05207
Chemical carcinogenesis - receptor activation
bmus05208
Chemical carcinogenesis - reactive oxygen species
bmus05210
Colorectal cancer
bmus05211
Renal cell carcinoma
bmus05213
Endometrial cancer
bmus05214
Glioma
bmus05215
Prostate cancer
bmus05220
Chronic myeloid leukemia
bmus05221
Acute myeloid leukemia
bmus05223
Non-small cell lung cancer
bmus05224
Breast cancer
bmus05225
Hepatocellular carcinoma
bmus05226
Gastric cancer
bmus05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118906231 (SOS1)
04012 ErbB signaling pathway
118906231 (SOS1)
04014 Ras signaling pathway
118906231 (SOS1)
04630 JAK-STAT signaling pathway
118906231 (SOS1)
04068 FoxO signaling pathway
118906231 (SOS1)
04072 Phospholipase D signaling pathway
118906231 (SOS1)
04151 PI3K-Akt signaling pathway
118906231 (SOS1)
04150 mTOR signaling pathway
118906231 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118906231 (SOS1)
04540 Gap junction
118906231 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118906231 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
118906231 (SOS1)
04660 T cell receptor signaling pathway
118906231 (SOS1)
04662 B cell receptor signaling pathway
118906231 (SOS1)
04664 Fc epsilon RI signaling pathway
118906231 (SOS1)
04062 Chemokine signaling pathway
118906231 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
118906231 (SOS1)
04912 GnRH signaling pathway
118906231 (SOS1)
04915 Estrogen signaling pathway
118906231 (SOS1)
04917 Prolactin signaling pathway
118906231 (SOS1)
04926 Relaxin signaling pathway
118906231 (SOS1)
04935 Growth hormone synthesis, secretion and action
118906231 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
118906231 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
118906231 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118906231 (SOS1)
05206 MicroRNAs in cancer
118906231 (SOS1)
05205 Proteoglycans in cancer
118906231 (SOS1)
05207 Chemical carcinogenesis - receptor activation
118906231 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
118906231 (SOS1)
05231 Choline metabolism in cancer
118906231 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
118906231 (SOS1)
05225 Hepatocellular carcinoma
118906231 (SOS1)
05226 Gastric cancer
118906231 (SOS1)
05214 Glioma
118906231 (SOS1)
05221 Acute myeloid leukemia
118906231 (SOS1)
05220 Chronic myeloid leukemia
118906231 (SOS1)
05211 Renal cell carcinoma
118906231 (SOS1)
05215 Prostate cancer
118906231 (SOS1)
05213 Endometrial cancer
118906231 (SOS1)
05224 Breast cancer
118906231 (SOS1)
05223 Non-small cell lung cancer
118906231 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
118906231 (SOS1)
05160 Hepatitis C
118906231 (SOS1)
05163 Human cytomegalovirus infection
118906231 (SOS1)
05165 Human papillomavirus infection
118906231 (SOS1)
09165 Substance dependence
05034 Alcoholism
118906231 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118906231 (SOS1)
01522 Endocrine resistance
118906231 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
118906231
NCBI-ProteinID:
XP_036729560
UniProt:
A0A8C0DCM7
LinkDB
All DBs
Position
13:58707251..58859749
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSVSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
SDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcagggccaagttcatcctactcttgagtct
agtgatgacgctcttcagtatgtggaagaattaattctgcagttattaaatatgctatgc
caggctcagccccgaagtgcttcggatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaagcaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaacttaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtggatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agttgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggttttcatgatcgtttccttagtcagttatcaaagcctggagcg
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagccttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccaatgagtacaagcatgcttttgaaataattctgaaagat
gaaaatagcgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgacgtgacaatgctccag
gaagaaaaggaggagcagatgaggctccccagtgctgatgtgtatagatttgcagagcct
gactctgaagaaaatatcatatttgaagagaacgtgcagcccaaagctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttttaatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctacgattttgaaagagacgcagatcttttgcagcgaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaagtgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttactggaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaggaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcacctgtatacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagt
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagtaggatccctgaaagtgaaacggaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgactctgatcattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagatcatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgatattcagtatcagac
cggacctctatatcagatcctcctgaaagccctcccttattacctccacgagaacccgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccttccccctttacaccacctccg
cctcaaacaccttctcctcacggcacaagaaggcatctgccatcaccaccactgacacaa
gaagtggaccttcattccattgctgggcctcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccgaaaacttacaaaagggagcatacacacccatccatgcac
agcgatggaccaccgctgttggagaatgcccattcgtcctga
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