Brucella melitensis M28: BM28_B1083
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Entry
BM28_B1083 CDS
T01852
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit beta
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
bmz
Brucella melitensis M28
Pathway
bmz00280
Valine, leucine and isoleucine degradation
bmz00640
Propanoate metabolism
bmz00785
Lipoic acid metabolism
bmz01100
Metabolic pathways
bmz01110
Biosynthesis of secondary metabolites
bmz01210
2-Oxocarboxylic acid metabolism
Module
bmz_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bmz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BM28_B1083
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BM28_B1083
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BM28_B1083
Enzymes [BR:
bmz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BM28_B1083
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GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
ADZ68332
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Position
2:1067109..1069286
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AA seq
725 aa
AA seq
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MAEKIDLKPSAPWYRLNTTDEDWQNAEAADLLKWYSQMKLIRRFEEKILDFEKAGLVHGP
AHASIGQEAAAVGAMSVLKTDDQINGTHRAHHQVLTKLINAQTPSDFDILQSDFTDGMHD
AVYRLMAEIMGLNTGYCGGRGGSMHMRDAASGIAGTSAIVGGNIPHAAGYALADKILNRK
GISVAFFGDGPSLQGATYEAMNIAALYRLPVIFYVENNLYAVSTHIQDATRETRIASRCP
MLGFTGIECDGMDILSVHQAMREACRIIEEEGGPVVIEAQCYRYLHQSGSKSGSDFGYRT
REEEEEWKSRDPIALAERRLKELGIAGDAEFLKIDERVTAAVQAAGERLTETAAGSNVLR
IPDALWPSASSVDDGILGDGSEFSGAEFREIEDYQPDELEKMRFAAAASDVLGRAMEKDP
TIIVIGEDVHRFAGGVSGFTRNALELFPDRVLAMPIAENGFTGVVLGAALRGLRPVVEIM
FGDFCFVAADQIANGISKVRHMFGDGFPVPIVMRVRVSPHTGYGSQHSGDPSALFGMFPG
WRVVSPTNAFDYIGLMNSALKSDDPVAVIEHVEFYQRESLVPRNDRDYCIPLGKAKIVRP
GSACTVLATSVMVQASIKAAEEAGIDAEIIDMRSLDMFGIDWALIGASIGKTNRVVIAEQ
VASGLSLGRHWIAEIQKRFFNDLDHEVLHVTGSMASPVVSLVLNKAALGSADKVRSALEQ
ITHSA
NT seq
2178 nt
NT seq
+upstream
nt +downstream
nt
atggcagagaaaattgatctgaaaccatccgcaccctggtatcggttgaataccacggac
gaggattggcaaaatgcagaagcggccgatctgctgaaatggtatagccagatgaagctg
atccgccggttcgaagaaaagatactcgattttgaaaaggcgggtctggtccatggaccg
gcccatgcaagcattggtcaggaggctgctgcggtcggcgccatgtcggtgctgaaaacc
gatgaccagatcaatggcacgcaccgcgcccaccatcaggtcctgacaaaactgatcaat
gcccagacgccatcggatttcgatattcttcagtccgatttcaccgatggcatgcatgac
gcggtttatcgcctcatggccgaaatcatggggctgaatacgggctattgcggcgggcgc
ggcggctcgatgcatatgcgcgatgcggcttcgggcattgccggaaccagcgcgatcgtc
ggcggcaatattccccatgccgccggttatgccctcgcagacaagatcctcaaccggaag
ggaatttctgttgccttcttcggcgatggcccttccttgcagggcgcgacctatgaagcg
atgaacatcgccgcgctctaccgcctgccggtcattttttacgtggagaataatctctac
gccgtatcgacccatattcaggatgcaacgcgcgagacgcgcattgcctcgcgctgtccc
atgctcggctttaccggcatcgaatgcgacggcatggacattctttccgtccatcaggcg
atgcgtgaagcctgccgcattatcgaggaagagggcggtccggtcgtcatcgaggcgcag
tgctacagatatctgcatcaaagcggcagcaaatcgggcagcgatttcggttatcgcacg
cgtgaggaagaagaggaatggaaaagccgcgatccgattgcgcttgccgagcggcgcctg
aaggaactggggatcgcgggagatgccgagtttttgaagattgacgagcgtgtgaccgcc
gccgttcaagcggctggagagcgcctgaccgaaacggccgccggcagcaatgttctgcgt
attcccgatgcgctttggccgtcggcatccagtgtggacgacgggattttgggagatggc
agcgaattttccggtgcggaatttcgcgagatcgaggattatcagcccgatgagctggaa
aagatgcgctttgccgcggcggcttcggatgtgctcgggcgggcgatggaaaaggacccg
acgatcatcgtcataggggaggatgtccatcgttttgcaggcggtgtcagcggctttacc
agaaacgcgcttgagctttttcccgaccgggttctcgccatgcccatcgccgaaaacggc
tttaccggcgtagtgcttggtgcagccctgcggggcctgcgcccggtggtggaaatcatg
ttcggtgatttctgctttgtcgcggccgaccagatcgcgaacgggatttcaaaagtgcgt
catatgttcggcgacggttttccagtccccatcgtcatgcgtgtgcgcgtttcgccccac
accggctatggttcgcagcattccggcgatccctcggcactgttcggcatgtttcccgga
tggcgcgtcgtctcgcccacaaatgcctttgattatatcggcctgatgaacagcgcgctg
aaatcggacgatcccgtcgcggttattgagcatgtcgagttttaccagcgcgaaagctta
gttccgaggaatgacagggattattgcatcccgctcggcaaggcgaagatcgtgcgtccg
gggtcggcctgcaccgttcttgccacatccgtcatggtacaggcttccatcaaggctgcg
gaagaggcgggcatcgatgccgaaatcatcgatatgcgcagcctcgacatgttcgggatc
gactgggccttgattggcgcttccatcggcaaaaccaaccgggtggtgattgccgagcag
gttgcaagcggcttgtcgctcggacggcattggatcgccgaaatccagaagcgcttcttc
aacgatctcgaccatgaagtcctgcatgtgacgggaagcatggcctcgccggtcgtgtcg
ctggttttaaacaaggccgccctcggatcggccgacaaggtccggtcggcccttgagcag
attacgcattccgcatga
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