Bactrocera oleae (olive fruit fly): 106619525 Help Entry 106619525         CDS       T07646                                  Name (RefSeq) ryanodine receptor isoform X13   KO K04962   ryanodine receptor 2 Organism bod  Bactrocera oleae (olive fruit fly) Brite KEGG Orthology (KO) [BR:bod00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:bod04040]     106619525    04990 Domain-containing proteins not elsewhere classified [BR:bod04990]     106619525 Ion channels [BR:bod04040]  Voltage-gated cation channels   Ryanodine receptor    106619525 Domain-containing proteins not elsewhere classified [BR:bod04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    106619525 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 GWT1 DUF4639 Motif Other DBs NCBI-GeneID:  106619525 NCBI-ProteinID:  XP_014093112 LinkDB All DBs Position Unknown AA seq 5130 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTASGSETGKGTGSGHRTLLYGNAILLRHHNSDMYLACLSTS SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE NEQSIVNASFHVTHWSVQPYGTGISRVKYVGYVFGGDVLRFFHGGDECLTIPSTWGREPG QNIVVYEGGSVMSQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNENNELVL VKKEEASIASTTFCLRQEKDDEKKVLEDKDLEVIGVPIIKYGDTTVIVQHCESSLWLSYK SYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFINALE TLQSNRRHSIFFQQVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEE GVLNLILEAIDKINVITSQGFLASYLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQF ANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRD PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVGQVDGS AMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGKKWGGNGAGDDLYSFGFD GAHLWTGGRRTLVVNNLPQEPYIRKGDVIGVTIDLSIPIITFSFNGSKVLGCFRDFNLDG MFFPVMSCSSKLSCRFLFGGDHGRLKFAPPLGFSPLVQCLMPHQNLSLDPCFYYGNLNKN VLAGPWLIEDDTAFVPNPVDTSGVLLPSSVDHIKEKLAENIHEMWALNKIEAGWSWGEHR DDYQRIHPCLTQFEKLPLPERRYDSQLAVQTLKTILALGYYITMDKPPARIRPIRLPNEI FMQANGYKPAPLDLNAVTLSPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSENHRS PHLVPYSKVDEAIKKANRDTASETVRTLLVYGYILDPPTGEGNEGLLAEAQRLKFAAFRT YRVERNYAVTSGKWYFEFEVLTAGPMRVGWARADCHPGIMLGSDDSSWAFDGHNEEKIAG GTCESFGKQCGHGDIVGVFLDLADHTISFSLNGELLMDALGGETTFAEVSAEGVGFVPAC TLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMP DCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMSQFINELEKSHRWE EIKIRQYRLQREAQDLAIQQQQAAANVDHMLKGGFTMSDIKGLHQNFEDAVESDEQLSRI PARPPRRNSLTRNITFESDVTSDTRGSAAFDMVNGINGLNGTDEGIDDKKKRGRSPFKFF SKKTRDQSKDKTGGTFQEPSLERRNTVAHGRNVVNAQLSTKTPTLRLNNADMPIQQGPKQ LTSTTLGQPTIESAGNELFDTECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLHSKE FNKSKVRCVSVVIEDEYEVIRDRIDRQSCYVVRADELFNEVTQDSSGKGASQGMFIGCFV DTSTGIIRFTCEGKETTHRWMMEPDTKLFPAIFVEATSKEILQIELGRTSTTLPLSAAVL PTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDIRGWSMLCEDPVSMLALH IPEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNYRAAHALCQHVDQKQLLYAIRS EYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYIIPLGTELKELYSDDEMCHSLRSLIT ESVRPQMRMTDITPPVYSYTSSLPSVSSEPIPNIDQLYSPKFPLEVVREFVMEALKEAVE VNQVHNRDPIGWTNENLFLPLLKLTDRLLLVGVLTDVDVQKLLIMIDPETWDITFEKDGK DEHRKGLLTMKMAEGAKLQMCYLLHHLYDIQLRHRVESIISFSHDFVGDLQGDQLRRYIE IKQSDLPSAVAAKKTKEFRCPPREQMNQILCFKNLESDDQENCTCGLDLRSRLYDFHDSL MKKVSLNALHEPDEVDCNAIEEVKAGPVTKIYNFINAVKELEEGPKEIEEPEKKTPEEVF RKVLIKTIVSWAEESQIENPKLVREMFSLLVRQYDTVGELVRALGKTYVINNRARDDVAE MWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRIHENVMAVMMNT LGRRAQAQSDAPPQTEGVEGAPPKEKDTSHEMVVGSCRFLCYFCRTGRQNQKAMFDHFDF LLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSEL VEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGE GLFRAIVEANRMSERISDRCNMQNEAEGTIAGLNFTHPLPEGDEDEDYIDTGAAILNFYC TLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLTQTPPGEERPK SDMPSGLLPNNKQSIVLFLERVYGIETQDLFYRLLEDAFLPDLRTATILDKSDGSESDMA LSMNRYIGNSILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDFL VALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSSQGQGSYGAS SDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYGR QSGAPDQPQYDPQPIDTEQVQLNNDLETLVQKFSEHYHDAWASRRLENGWSYGEIRSDND RKHPRLKPYNMLSDYERERYRDPVRECLKALVSIGWRIEQSDIDVPLNHRGSTRRQSKPQ INDFQSESSPFNYNPHPVDMTNLTLSREMQNMAERLAENSHDIWAKKKKEELNSCGGVIH PQLVPYDLLTDKEKRKDRERSQEFLKYMQYQGYKLHKPSKGGVTEGEGGATQAAVELRFS YSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTASRDIKFFSKVVLPLMEKYFSTHRN YFVAMATATNITGAASLKEKEMVASIFCKLASLLRNRLTAFGPDVRITVRCLQVLVKGID AKTLVKNCPEFIRTSMLTFFNQTADDLGNTILNLQEGKYSHLRGTHLKTSTSLSYVNQVV LPALTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHERKYLKTEIERHR PTLGSCLGAFSSCFPVAFLEPHLNKHNQYSLLNRIADHSLEAQDIMVRMESCMPNLESIL GEVDIFVESEKTYIDAPHIIDVILPLLCSYLPFWWAQGPDNVSPTSGNHVTMVTADHMNS LLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMFH KEESMRGFIKSATDDTSQVETQLQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEA EDLYNHVAEIFNIWSKSQYFLKEEQNFISTNEIDNMALIMPTATRRSAITEGAPVTGGKV KKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMQEYD VIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKREELADEQALEKLSNQNDKGKDKTQET VDRIVAMAKVLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNI FARSYYEQWLQEENVGQEIMIEDLTQTFEESEKSKKEEEESEGKPDPLTQLVTTFCRGAM TERSGALQEDLLYMSYAQIAAKSCGEEEEEGGDEEGGGEGKEEGASIHEQEMEKQKLLFH QARLSNRGVAEMVLLHISASKGVPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKKDV GFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQLTC EGHNLDWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFF KAIGVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDL LKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESAGNVELILKYFDMFLKLKDLI ESPSFAEIDIKNEGWVTPKDFRDKMEQSKNYTPDEMDFLLACCERNHEGKIDYGDFVDRF HEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRIER VYFEIKDSNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLM ATDDGGGNVKRDTAYSSYMSEEEEERAARDPIRRTMQAIKDGLRFIVHILSPSNIKHQIG IMQTKSVAELIIGFFKMIFYIFFYTGYGNFCVVRYIFGILMNLMRGPAPEEVEAPPVEEE TFGKMLPPSPIEEPPGPVQAFGLEFNKEENGQFKVTVRESSGGSGNSSLEETSESSQEEG GTAADQAVENEPYQLQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAEAKKKSS ATAQETPAVNQIDFAQYAHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFGDDGE ASGDDELILGSGSGGSLTASGFGGGSGDYSGDGAGDEEDLPELVHVDEDFFYMAHVIRIA AFLHSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIADQPEDDDFKSHWDKLVI SAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSAFMAQESEEGGLVKYIMNID WRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTH NGKQLVLTVMLLTIVVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVRA GGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKEN MESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNM YQQRSWDFFPVGDCFRKQYEDELSGGGGGG NT seq 15393 nt NT seq  +upstreamnt  +downstreamnt atggctgaagccgaaggtggttccgagcaggatgatgtttcgttcctgcgaacggaagat atggtgtgtctctcatgtaccgccactggtgaacgcgtctgtttagcagctgaaggattt ggtaatcgccattgttttttagaaaatatagcggacaaaaatattccgccagatctatcc caatgcgttttcgtaattgagcaggcactatcagttcgagcattgcaagaattagtaact gcgtctggatcggaaactggaaagggcactggatctggtcacaggacattgctttatggt aatgctatacttttacggcaccacaatagtgatatgtacctagcgtgcctttccacttct tcttcgaacgataagttgtctttcgacgttggattgcaagaacatagccaaggtgaggct tgctggtggacagtacatccagcaagtaaacagaggtctgaaggcgagaaagtacgagtg ggtgatgatctgattttagtctccgtagccaccgaacgatatttgcacaccactaaagaa aacgaacagtcaattgttaacgccagttttcatgtaacgcactggtcggtgcaaccttat ggtactggcatatcacgagttaaatatgttggatatgtgtttggcggtgatgttttacga ttttttcatggcggtgatgaatgtttaactataccaagtacatggggtcgtgaacctggc cagaacattgttgtgtatgagggtggctcagtaatgtcgcaagctcgatcgttgtggcgt ctggaattggcacgcactaaatggactggtggctttattaactggtatcatccaatgcgc atacgtcatattaccactggaagatatcttggggtgaacgaaaataacgaattagttttg gtgaaaaaagaggaagcttctattgcatcaacgactttctgcttaaggcaagaaaaagac gacgagaaaaaagtactggaggataaagatctagaagtaatcggtgtacctatcattaaa tatggcgatacgactgttattgtgcagcactgtgagtccagcctgtggcttagctacaaa agctatgaaactaagaaaaagggtgtcggcaaagtggaagaaaagcaggcaatccttcat gaagagggaaaaatggacgattgtttggacttttcacgatctcaagaagaggaatccaaa actgcccgtgttattcgaaaatgcagtagtctttttacacaattcatcaatgctttggaa acactacaatccaatcgacgacattcaatattctttcaacaagtaaatttaaacgaaatg gtcatgtgccttgaggatttaataaattacttttcgcaacctgaagatgacatggaacac gaagaaaagcaaaatcgttttcgagcactccgaaatcggcaggatctctttcaagaagaa ggtgttctaaatctaatattggaggctattgataaaattaatgttatcacttcacaagga tttttagccagttatttggcaggtgatgagactggtcaaagttgggacctaatatcgact tacctttatcaacttttggccgcaataataaaagggaaccatactaattgtgctcagttt gccaacagtaaccgtctaaattggctattttcacgattaggctcacaagcatctagtgaa ggatccggcatgttggatgtattgcactgtgttttaattgactccccggaagcactaaat atgatgcgcgatgaacatattaaagtaataatttcattacttgaaaaacatgggcgagac ccgaaagttcttgatgtactatgttcactgtgcgtaggcaatggagtggcggttagatca tcccaaaataatatttgcgattttctgttgcctggaaaaaatttattactgcaaacacaa cttgtagatcacgtcgccagcatacgtccaaatatttttgttggtcaagtagatggatct gcgatgtaccaaaagtggtacttcgaagtcactatggatcatattgaacaaactactcac atgatgccacatttgagaataggatgggccaatacctctggctatgttccatatccaggt ggtggaaaaaagtggggaggaaacggtgccggtgatgatctttattccttcggttttgac ggcgcccatttatggacgggtggtcgacgaactttggttgttaacaacttaccacaagaa ccatatattcgaaaaggagatgttatcggcgttactatcgatctttcaatacctattatt actttttcttttaacggtagcaaggttctcggatgtttcagggattttaatttggatgga atgttcttccctgtaatgagttgttcttcaaagttgagttgtcgctttctttttggtgga gaccacggccgtcttaaatttgctccacctctgggtttctccccactggttcagtgtttg atgccacatcaaaatctaagtttggatccttgtttttactatggaaacttaaacaaaaat gttttagctggaccgtggctaatcgaagatgacactgcatttgtacctaaccctgttgat acttctggagtcttacttccttcctctgtggatcacataaaggaaaagctggcagaaaac atccatgaaatgtgggcactaaacaaaatagaagcaggctggtcctggggtgagcacaga gatgactaccaacgaatacatccatgtcttacgcaatttgaaaaactacctttaccagag cgtcgctacgatagtcaactggcggtgcaaacacttaagaccatattagctcttggatat tatattactatggataagccgcctgcgcgtattcgtcctattcgattaccaaatgaaatt tttatgcaggctaatggctacaaacctgctcccttagacctcaatgcagtcactctatct ccaaaattggaggaactagtagaccagttggctgaaaatacacataatttatgggctcgt gagcgaatccaacaaggttggacttatggactcaatgaagactccgaaaatcaccgcagc ccacacttggtgccttactcaaaagtggatgaggcaattaaaaaagcgaatcgtgatacc gcttctgaaacagtacgtactctcttggtatatggatatatattagatccaccaactggt gaaggcaatgagggattactagccgaagcgcaacgattaaaatttgctgcatttcgcacg tatcgcgtcgaacgtaattatgctgtgacatctggaaaatggtattttgagtttgaagtt cttactgctggtccaatgcgtgtaggatgggctagagcagactgtcatccagggatcatg ttgggcagcgacgactccagttgggcttttgacggacataacgaagaaaaaattgctgga ggtacctgcgaatcatttggtaaacaatgcgggcatggcgatattgtaggcgtgttctta gatctcgccgatcacacaatcagtttttcacttaatggagaacttcttatggacgcttta ggcggtgaaacaacttttgcagaggtgtctgctgaaggagtgggatttgtacctgcttgc actttaggtgtgggacaaaaagcacgtttaatatacgggcaagatgtcgactcgttgaag ttttttactacatgtggactccaggagggctatgaaccgttttgtgttaatatgcgtcgc ccggtaactcattggtacaccaaagatcaaccaatttttgaaaacactgaagaaatgcct gactgtcgaatagatgttacacgtatcccagggggggcagatacccctccacatttgaag atatctcataatacgtttgagactatggaaaaggctaattgggaatttttacgactttct ctacctgttacttgcatgagtcaatttataaatgagttagaaaagtctcatcgatgggaa gaaattaaaatacgacagtatcgactacaacgcgaagctcaagacttagctattcaacaa caacaagctgctgccaatgtagatcatatgttgaaaggtggcttcaccatgagtgacatt aaaggtcttcatcaaaattttgaggacgcggtggaatcagatgaacaattgtcacgcatt cctgcaagaccccctcgtcgaaattccttgacacgtaatataactttcgagtcagacgtg acgagcgatacgcgaggatctgctgcgtttgatatggtaaacggtatcaatggattaaat ggtactgacgaaggaattgacgataaaaaaaaacgtggtcgaagccctttcaaatttttc tccaaaaaaacgcgggatcaaagtaaagataaaacaggtggcacattccaagaaccatca ctagaacgtagaaatacggttgctcatggtcgcaatgttgtaaatgctcaattgtctaca aaaacaccaactctacgcttgaataatgctgatatgccgattcaacaaggccctaagcag ctgacctctaccactttggggcaaccaactatcgaatcagctggcaacgaattatttgac actgaatgtctgaagttgatcaatgaatatttttacggcgttcggatatttcctggacaa gatccaacacatgtctatgtcggttgggttacaacacaatatcatcttcacagtaaggag ttcaacaaatcaaaagtacgatgcgtttccgttgttattgaagacgaatatgaagttatt agggatcgtattgatagacagagttgttacgttgtaagagctgatgaactttttaatgaa gtaacgcaagattcttcaggaaaaggcgcctctcagggaatgtttattgggtgttttgtg gacacctcgactggtattattcgttttacatgtgaggggaaagagacaactcaccgctgg atgatggaaccagacacaaagctttttccagcaatatttgtggaggcaactagtaaagaa attttacagattgaactgggccgaacatctacaactttacctctttctgctgctgtcctt cctacaagcgataaacatattaatcctcagtctcctcctcgccttaaggtacagtgtctc cggcctcatcaatgggcacgtgttccaaatacagctctgcaagtacatgctctcaaactt tccgatatacgtggttggtctatgctgtgcgaagatccagtgtcaatgcttgcccttcac atacccgaagaagatcgctgcattgacattttggagttaatagagatggacaaattatta tcatttcatgctcatacccttacattatatgctgcactttgttaccagtcaaactatcgt gctgctcatgctctttgtcagcatgttgatcaaaagcagcttctttacgcaataaggtcg gaatacatgagcggacctcttcgacaaggattttacgacctattaattgctcttcatttg gagtcacatgccactaccatggaagtatgtaagaatgaatacataattccactcggaact gagctaaaagaattgtacagcgatgatgaaatgtgccactcgttgcgctcactcataaca gagtcggtgcgtccccaaatgcgaatgacagatattacaccccctgtatatagctataca tctagtttaccaagtgtttccagtgaaccaataccaaacatcgatcagctgtattctccg aaatttccacttgaagtagtaagagagtttgtaatggaggcattgaaagaagcagttgaa gtcaatcaagttcacaaccgtgatccaattggttggactaatgagaatctattcctccca cttcttaaacttactgatcgattattattagttggcgttcttacggatgtagatgtacaa aagctactcataatgattgatcctgaaacatgggatatcacattcgaaaaagacggcaaa gatgaacatcgtaaaggacttttgactatgaaaatggccgaaggagctaagcttcaaatg tgttaccttcttcaccacctttacgacatacagctgcggcatagggttgaaagtatcata tcattttctcatgattttgttggtgatttgcaaggcgatcagctccggcgatacattgaa ataaaacagtcggaccttccaagtgccgtggccgcaaaaaaaactaaagagtttcgttgt ccccctcgagagcagatgaatcaaatactgtgttttaaaaatcttgagtctgatgatcaa gaaaattgtacttgtggcttagatttgagaagtcgattgtatgattttcatgatagcctt atgaaaaaggtatctcttaatgcgctgcatgaacccgatgaagtcgattgtaatgcaata gaagaagtgaaagcgggaccagttacaaaaatttataattttataaatgctgttaaagaa cttgaggaaggacctaaagaaattgaggaaccagagaagaaaactccagaagaagttttt cgaaaagtattaataaaaactatagtcagttgggctgaagaatcgcaaatagaaaacccg aagcttgtgcgtgagatgttcagtttgttagtccgccaatatgatactgtgggggaactg gtacgagcacttggtaaaacctacgttattaataacagagctagggatgacgtagctgag atgtgggttggcttaagtcaaattcgcgctttacttccggtacaaatgagtcaagaagag gaggagcttatgaggaaacgcctttggaaattggtaaataatgctacattcttccaacac cctgaccttatacgaatattaagaatccacgagaacgtaatggcagttatgatgaataca ctaggaagacgtgctcaagcacaaagtgacgcacccccacagacagaaggggtagaaggc gcacccccaaaagaaaaagacacatctcatgaaatggtggtcggaagctgccgcttcctt tgttacttttgtcgtacaggtcgtcaaaatcagaaggccatgtttgatcattttgacttc ttattagacaacgcaaatattctactggcaagaccaagcttacgaggttcaaccccatta gatgtggcatattcaagcttgatggaaaatacagaattggctctagcactaagggagcat tatttagaaaagattgctgtttatttgtcacgatgtggattacaaagcaattcggaacta gttgaaaaaggctatccagacttgggatgggatccagtggaaggtgaacgttatttagat ttccttagatattgtgtatgggtaaacggggaaagcgtcgaagaaaacgcaaaccttgtc attcgtcttcttatccgccgtccagaatgtttaggaccggctctaagaggagaaggggaa ggcttattccgcgcaatagtggaagctaaccgaatgtcagagcgtatttctgatagatgc aacatgcaaaatgaggcggaaggaactattgctggtttaaacttcacacatccattacct gaaggagacgaggatgaagactacatagatactggtgcagcgattctaaatttttattgt acgcttgttgatcttcttggaagatgtgctccagatgcttccgtcattgaacaaggaaaa aatgaatcgcttagagctagagctattttgagatcattggtcccactggaagatcttcaa ggtgttctcagtttaaaattcacattgacacaaacaccaccaggagaagagagaccgaaa tcagatatgccgtccgggcttctaccgaacaataaacaaagcattgttctatttttggaa cgagtgtatggtatagaaactcaagatttattctaccgtttactggaagatgcattttta cctgatttaagaacagccactattcttgataagagtgatggttcggaaagtgatatggcc ctttccatgaatcgttatattggtaattctatactgccattacttataaaacattcgaaa ttttacaatgaagcggaaaactatgccagccttttggatgcaaccttgcacacggtatat cgactgtcaaagaatcgtatgctaacaaagggccagagagaggctgtatcggatttcttg gtggcgcttacatcccagatgcaacctgccatgttattgaaactattacgcaagttgact gtggatgtctccaaactatctgaatatactaccgtggctttaagactactcactcttcac tttgatcgttgtgcaaaatattacggttcatctcaaggtcaagggtcatatggggcatcg tctgatgaagaaaaacgactgacgatgcttctattctcaaatattttcgattcgctcagt aatatggattatgacccggagttatttggaaaagcattaccttgtttaattgctattgga tgtgcattgccgcctgattacagtttatcgaaaaatactgatgaagactattatggtcgg caatcgggagctccagatcagccacaatatgatccccaacctattgacacagagcaagta caattaaacaatgacctcgaaacactggtgcaaaaatttagtgaacattaccatgatgcc tgggcaagtcgacgtttagaaaatggatggtcgtatggtgaaatacgttcggataatgat cgaaaacatcctcgcctgaagccttacaacatgttaagtgattacgaacgtgaacgttat cgagatccagtaagagaatgtctgaaagccttagtttctattggttggcgcattgaacag tcagatattgatgttcccctcaatcatcgcggatcaactcgtcgtcaatccaaaccacaa atcaacgattttcagagtgaaagcagtccattcaactataacccacatccggtagatatg acaaatctaaccctaagtagagaaatgcaaaatatggcagaacgtttggctgagaactct catgacatatgggcaaagaagaagaaagaagagcttaactcctgcggcggtgttatacat cctcaactggttccttatgacttattaacagataaggaaaaacgtaaagaccgtgaacga tcacaagagttcttaaagtatatgcaatatcaaggctacaaattacacaagccctctaaa ggtggagttacagaaggggaaggaggagccacacaagcagcagtggaacttcgattttca tattctctactagaaaaattaattcaatatttggatcgtgctactattaatatgaagcta cttaagccatcaaccacatttagccgacgctcatcattcaaaacggcttcgcgtgacata aaattcttctcaaaagttgtacttccattaatggaaaaatatttttctacacaccgtaac tattttgttgcaatggcaacggcaacaaacatcacaggtgcagcttctctgaaggaaaaa gaaatggtggcatctatattttgtaaattggcatcacttcttcgtaatcgcctcactgcc tttggaccagatgtgcgaatcacagtgcggtgtcttcaagtattagtaaagggtatagat gctaaaacactagtaaaaaattgtccagagtttataagaacatcaatgctaacatttttt aatcaaactgctgatgatctgggtaatacgattcttaatttacaagagggcaagtatagt catcttcgtggcacacatttgaaaacatctacttcgttaagctatgtaaatcaagtagta ctgccagcattaactgctatgtttgatcatttagctgcttgcgattatggtagtgatctt ctattagacgaaatacaagtggcttcatacaaaatattagcagcattgtatcacctagga accgatggaacactcacacatgaacgaaaatatttgaaaaccgaaattgagcggcatcgg cccacattaggctcgtgcttgggtgcattcagttcttgtttcccagtcgctttcttagaa ccacatctaaataagcataaccaatattcactacttaatcgcattgcagaccactcatta gaagctcaagatattatggtgcgtatggaaagctgcatgccaaatttagaaagtattctg ggagaagtcgatatctttgttgaatcagaaaaaacatacattgatgcaccgcatataata gacgttattttacctttactatgctcctatcttccgttttggtgggcacagggtccggat aatgttagtcccacgagtggtaatcacgtgaccatggtaacagcagatcatatgaactca cttctccgtaacgttttgaaaatgattaaaaagaatattggaaatgataatgccccttgg atgacgaggatcgctgcatacactcaacaaataattattaacacttctgaagagttgcta aaagatccgtttttgccactcgccgagcgtgtgaaaaaacgtacagaaaatatgtttcat aaggaagagagtatgcgtggttttattaaatcggccacagatgacacttctcaagttgaa actcagttacaagaagactggcaacttcttgttcgggacatttattcattttatccactt ttaatcaaatatgttgatctgcaacgtaatcactggcttaaagacaatatccccgaagcg gaagatttatataatcatgtagctgaaatctttaacatatggtcaaagagtcaatacttt cttaaagaagaacaaaactttatttcgaccaatgaaattgacaatatggcgcttattatg cctacggctacaaggcgatcagcaattactgaaggtgcacccgtaacgggtggtaaagtt aagaagaagaaaaagaacagagataaaaagagagacaaagataaagaagtacaagctagt ctaatggtagcttgtctgaagcgtttgcttccagttggcttaaatctgtttgctgggaga gaacaggagcttgtacaacattgcaaagatcgctacttgaaaaaaatgcaggaatatgat gtcatagaatttgctcgaaatcagttgacacttcctgacaaattagatccttcagatgaa atgtcatggcagcactatttgtattcaaagttgggaaaaagggaggaactcgcagatgaa caggcattggagaaactttcaaatcaaaatgataagggcaaggacaagacgcaagaaact gttgaccgtatagtagccatggccaaagttcttttcggtttgcatatgattgaccatccc caacaacaaagcaagaacgtctacaggagtgttgtatccatacaaaggaaacgtgctgtt atcgcatgtttccgtcaaacatctctacattctctacccagacatcgagcctgcaacatt tttgccagatcctactacgagcaatggcttcaagaagaaaacgtgggtcaagagataatg attgaagacttgactcaaacgtttgaggaatcggagaaatccaagaaagaagaagaagag tctgaaggtaagccagatccgctcacacaactagttactactttctgtcgcggagcgatg accgaacgaagcggagctttgcaagaagatttactttatatgtcatacgcacaaatcgct gcaaagtcctgtggagaggaagaagaagaagggggcgatgaagagggagggggagagggt aaagaggaaggagctagcatacatgaacaagaaatggaaaaacaaaaactcctcttccat caagcgcgactctcaaatcgtggcgttgcggaaatggtgctgcttcatatatccgcttca aaaggtgtcccctctgaaatggttatgacaacattaaatttgggtatagcaatactccgt ggtggtaatatagacattcaaatgggaatgttgaatcatctgaaggagaaaaaagatgtg ggtttctttacatcaattgcaggtcttatgaattcttgtagtgtactagatttggatgca tttgaacgcaatacaaaggcggaaggtcttggtgtaggttcggaaggagccgctggcgag aaaaacatgcatgatgctgagtttacttgtgcattatttcgattcattcaattgacttgc gaagggcacaacctagattggcagaactacttgcgtacgcaggcgggcaacacaaccaca gtcaacgtggtaatatgtactgttgattacttactacgtctacaagaatccataatggac ttctattggcactactctagtaaggagatcatagatccggcaggaaaggctaacttcttc aaagcgatcggtgtggcaagtcaagtatttaatacattgactgaggtcattcaaggtcca tgtacattaaatcaacaagctttagcacattctcgtttatgggacgctgttggtggtttc ctttttcttttctcacatatgcaagacaagttgtcaaaacattctagccaagtggactta ttgaaagagctgctcaatttgcagaaagacatgattactatgatgctttctatgctcgaa ggaaacgttgttaatggtacaattggaaaacaaatggtggacacactggtcgagtcagct ggcaacgtagaactaattctaaaatatttcgatatgtttttaaaattgaaagatttgatt gaatctccaagctttgcggaaatcgatataaaaaatgagggctgggtgactccaaaagat tttagggacaaaatggaacaatctaagaattacactccagatgaaatggactttcttttg gcttgctgtgaacgtaaccacgaaggcaaaattgactatggcgatttcgttgatcgtttt catgagccatcaaaagaaatcggttttaatttagccgtattgttgacgaatctgagtgag catatgccgaatgagcctcgtttagcccgattcttggagacagctggatcggtgctgaat tattttgaacctttccttggtcgtattgagattttgggtagctccaaacgtattgagcgc gtatattttgaaataaaagactcaaatattgaacaatgggaaaagccacaaattaaagaa tccaagagggcattcttctattcaatagtcactgaaggtggagacaaagaaaaattagaa gctttcgttaatttctgtgaagatgctatctttgaaatgactcacgcttcaggcttaatg gcaactgacgatggtggtggtaatgttaagcgggatactgcctacagttcctatatgagc gaagaagaggaggaacgtgccgcacgggatcctatacggcggaccatgcaagctatcaag gatggccttagattcatagtgcatatcttaagtccatcaaatataaaacatcaaattggg ataatgcaaaccaagtcggtagcagaactaattattggattcttcaaaatgatattttat atatttttttatactggctacggcaatttctgtgtcgttcgttacattttcggaattcta atgaatctaatgcgtggaccagcaccagaagaagtcgaagctccaccagtcgaggaggaa acatttggtaagatgttgccaccatcacctattgaagaaccaccgggaccagtgcaagcc tttggacttgaatttaacaaagaagaaaatggccagttcaaagtaacagttcgtgaatcg tctggtggtagtggtaactcgtcattagaagaaacgagtgaatcaagtcaagaagaggga ggaacagccgctgatcaagcggtagagaatgaaccgtatcaacttcaagaaccaatatca atcgttgacttactaggtggagaagctgccaagaaagcagcacaagaacgacaagaggcg caaaaggcccaagaagcggctatggcttcaattgaagccgaagctaagaaaaaatcgtca gcaactgctcaagaaacgccagcggttaatcaaattgactttgctcagtacgcacatcgt gccgttagtttccttgcacgcaatttttataaccttaaatatgttgcattggtgttagct tttagtattaattttatgttactcttctataaagtaacatcttttggcgatgatggagag gcttcaggtgacgatgaacttattcttggttctggatctggtggtagtctaacagcatcc ggatttggtggcggttcgggagattattctggggatggtgcaggcgacgaagaagactta ccagaacttgtacatgttgacgaagatttcttctatatggctcacgtcatacgcatagct gcttttttacatagtttagtctccctcgcaatgctaatagcatactaccatttaaaagtg cctttagccattttcaagagagagaaagaaatagctcgtcgattggaatttgatggtctc ttcattgcagatcaaccggaagatgatgattttaaatcacactgggacaaattagtgata tctgctaagtcatttcccgttaactattgggacaagtttgtgaaaaagaaggtgagacag aagtacagcgaaacatatgacttcgattcaatatcgaatctacttggaatggagaaaagt gctttcatggcgcaagagagtgaggaaggtggtttggtgaagtacataatgaatatagat tggcgttatcaagtatggaaagcaggggttacatttaccgataacgctttcctatactcg ctgtggtatttctcattctcagtgatgggcaacttcaataactttttcttcgcagcccat ttactcgatgtagccgttggatttaaaacgcttcgcaccattttacaatcggtcactcat aacggaaaacaacttgttcttactgtaatgctcctaacaattgtagtatacatttataca gtaatagctttcaacttcttccgcaaattttacatacaagaagaagatgaagaggtagat aaaaaatgtcatgatatgctgacttgttttgtattccacttatataaaggagtgcgagcc ggaggaggaattggtgatgaaattggagatcccgacggagatgactacgaagtttatcgt attatttttgacatcacattcttctttttcgttattattatacttctagcgattattcaa ggtttgattatagatgcttttggtgagttacgtgatcaacttgaatcggttaaggaaaat atggaatcaaattgtttcatatgtggcatgggaaaagatttttttgatatagttcctcac ggttttgatactcacgtgcaaaaggaacataatcttgcaaattacatgttcttcttgatg catctaatcaacaaaccggatacagaatacactggtcaggagacttatgtatggaatatg tatcaacagcggagttgggacttcttcccagtaggtgattgctttcgtaagcagtatgaa gacgagctgtcaggaggtggtggaggtggttaa

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