Burkholderia oklahomensis EO147: DM82_4058
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Entry
DM82_4058 CDS
T03284
Symbol
bkdA1
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bok
Burkholderia oklahomensis EO147
Pathway
bok00280
Valine, leucine and isoleucine degradation
bok00640
Propanoate metabolism
bok00785
Lipoic acid metabolism
bok01100
Metabolic pathways
bok01110
Biosynthesis of secondary metabolites
bok01210
2-Oxocarboxylic acid metabolism
Module
bok_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bok00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DM82_4058 (bkdA1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DM82_4058 (bkdA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DM82_4058 (bkdA1)
Enzymes [BR:
bok01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DM82_4058 (bkdA1)
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
LutB_C
Motif
Other DBs
NCBI-ProteinID:
AIO69893
UniProt:
A0AAI8BCZ8
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Position
2:370849..372081
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AA seq
410 aa
AA seq
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MSQYGPLRLHVPEPTGRPGCKTDFSYLHLSPPGKVRKPPIDVAPADTSDLAYGLVRVLDD
DGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHT
LALERGDMCFPTYRQQGILMVRDYPLVDMMCQLMSNERDPLKGRQLPVMYSTREAGFFSI
SGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVV
NNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPT
LIEWVTYRGGPHSTSDDPSKYRPGDDWTCFPLGDPLDRLKRHMIGIGVWSEQAHEDTKAA
FEADVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPEHLRRQRQQLGV
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagccagtacgggccattgcgattgcatgtgccggagcctaccgggcgtccgggatgc
aagaccgatttttcctatttgcacctgtcgccacccggcaaggtgcgcaaaccccctatc
gacgtcgcccccgccgacacgagcgacttggcctatggcctcgtccgcgtgctcgacgac
gacggacgagccgtcgggccatgggcgcccgatctcgatcccgacatcctgcgcaaaggc
atccgtgcgatgctgaagacgcgcatcttcgacgcgcgcatgcagatcgcgcagcgccag
aagaagatctcgttctacatgcaatgcctcggcgaggaagcgatcgcggtcgcgcacacg
ctcgcgctcgagcgcggcgacatgtgctttccgacctaccgtcagcaaggcatcctgatg
gtgcgcgactatccgctcgtcgacatgatgtgccagctgatgtcgaacgagcgcgatccg
ctgaagggccgccagctgccggtgatgtactcgacgcgcgaagccggcttcttctcgatc
tcgggcaatctcgcgacgcagttcattcaggcggtcggctgggcgatggcgtcggcgatc
aagggcgacacgcggatcgcttccgcgtggatcggcgacggcgcgacggccgaagccgac
ttccacaccgcgctcacgttcgcgcacgtgtaccgtgcgcccgtgatcctcaacgtcgtc
aacaaccagtgggcgatctcgacgttccaggcgatcgcgggcggcgaaggcgcgacgttc
gcgggacgcggcgtcggctgcgggatcgcttcgctgcgcgtcgacggcaacgacttcctc
gcggtgtacgccgcgtcccgctgggcggccgagcgcgcgcgccgcaacctcgggccgacg
ctgatcgagtgggtcacgtatcgcgggggcccgcactcgacgtccgacgatccttccaaa
taccgccccggcgacgactggacgtgcttcccgctcggcgatccgctcgatcgcctgaag
cgccacatgatcggcatcggcgtgtggtccgagcaggcgcacgaagacacgaaggccgcg
ttcgaagcggacgtgctcgccgcgcagaaggaagcggagcgctacggcacgctcgccgac
gagcacgtgccgaacgtcgcgagcattttcgaggacgtctacaaggagatgccggagcac
ttgcgccggcagcgccaacagctcggggtttga
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