Bos mutus (wild yak): 102267343 Help Entry 102267343         CDS       T02919                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism bom  Bos mutus (wild yak) Pathway bom04072   Phospholipase D signaling pathway bom04115   p53 signaling pathway bom04140   Autophagy - animal bom04150   mTOR signaling pathway bom04151   PI3K-Akt signaling pathway bom04152   AMPK signaling pathway bom04211   Longevity regulating pathway bom04218   Cellular senescence bom04714   Thermogenesis bom04910   Insulin signaling pathway bom04919   Thyroid hormone signaling pathway bom05163   Human cytomegalovirus infection bom05165   Human papillomavirus infection bom05168   Herpes simplex virus 1 infection bom05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bom00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     102267343 (TSC2)    04151 PI3K-Akt signaling pathway     102267343 (TSC2)    04152 AMPK signaling pathway     102267343 (TSC2)    04150 mTOR signaling pathway     102267343 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102267343 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     102267343 (TSC2)    04218 Cellular senescence     102267343 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102267343 (TSC2)    04919 Thyroid hormone signaling pathway     102267343 (TSC2)   09149 Aging    04211 Longevity regulating pathway     102267343 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     102267343 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     102267343 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     102267343 (TSC2)    05163 Human cytomegalovirus infection     102267343 (TSC2)    05165 Human papillomavirus infection     102267343 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:bom01009]     102267343 (TSC2) Protein phosphatases and associated proteins [BR:bom01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102267343 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Motif Other DBs NCBI-GeneID:  102267343 NCBI-ProteinID:  XP_070218705 LinkDB All DBs Position 25:complement(40395907..40427746) Genome browser AA seq 1814 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVARTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMVCLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYHMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLNIIERLLQQLQSLDSPELSAIVHDLLSTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDCLETERSSEKKAG GPLSPPAGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDVILKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKELKESSAADAFRCRSISVSEHVVRRIQTSLTSASLGSADENSMAQADDNLKNLHLE LTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLL GLDSGELQGGPELSSDPSMHVRQTKEAPAKLESQAGQQVYHGARDRVRSMSGGHGLRVGA LDAPACYFPSSPTSPGSQTAPASQPEKASAGSPLPAQKEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS AKPSPPPRSNTVASFSSLCQSRCQGKLHRSISWADSAVVLEEGGPGEAGLSAEPPELEDF EATLGSDGRCGRSDAFSRSSSTSSQEEKSFHAEELPPGGIPIERAVSSEGSRASVDLAFQ PSQPLSKSSSSPELQTLQDILGDPGDKAEVGRLSPEAKARSQSGILDGEGAAWSAPGEER RGRGPAQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKNRAGTSNTEKVP GINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQS NSELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIM QAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITP LDYECNLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDI YPSKWIARLRHIKRLRQRIREEAHYSSASLPLMQTHPPGHAKAPAQAPAESTPTYETGQR KRLVSSVDDFTEFV NT seq 5445 nt NT seq  +upstreamnt  +downstreamnt atggctaagccagcaagcaaagattcaggcttgaaggagaagttcaagattcttttggga ctggggactccacggccaaatcccaggtctgcagagggcaaacagactgagtttatcatc accgcggaaatcctgagagagctgagtgttgaatgtggcctcaataatcgcatccgggtg atagggcagatctgtgaggttgccagaacgaagaaattcgaagagcatgcggtggaagca ctctggaaggccgtctcggacctgctgcagccagagcggccacccgaggcccggcatgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcctgggcgttctcagg gccctcttcttcaaggtcatcaaggattacccctctaatgaagacctccacgagagactg gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaagaagagctg gcggactttgtcctgcagtggatggacgttggcctgtcctccgaattcctcctggtgctc gtgaacttagtcaaattcaacagctgttaccttgatgagtacatcgcatccatggtccac atggtctgcctgctgtgtgtccagaccgtgtcctccgtggacatagaggtgtctctgcag gtgctggatgctgtggtctgctacaactgtctgccagccgagagcctccccctattcatc gtcactctctgccgcaccatcaacgtcaaggagctctgtgaaccttgctggaagctgatg cgcaacctcctgggcacccacctgggccacagcgccatctaccacatgtgccgcatcatg gaagacagagcctacatggaggacgcaccactgctgagaggagccgtgttctttgttggc atggctctctggggtgcccaccggctctattctctcaagaactccccaacatctgtgttg ccatcgttttatgaggccatgacctgtccgaatgaggtggtgtcctacgagattgtcctc tccataaccagactcatcaagaagtacaggagggagctccaggccgtgacctgggacatc ctgctgaacatcatcgagcgcctgctccagcagctccagagcctggacagcccagagctg agcgccatcgtgcacgacctgctgagcacagtggaggagctgtgtgaccagaacgagttt cacggctcccaggagagatactttgaactcgtggagaggtgtgcggaccagaggcctgag tcatcccttttaaacttaataacctacagggctcagtccatccatccagcgaaggacggc tggatccacaacctgcagctgctgatggagaggtttttcaggaacgagtcacgcagcgcc gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaggagcttatcaactcagtggtcatctcgcagctctcccacatccctgaggataga gaccaccaggtccggaagctggccactcagctgctggtagatctggccgaaggctgccac acccaccacttcaacagcctgctggacattgttgagaaggtgatcgcccgttccctctct ccgccccccgagctggaggagagggatgtggccgcgtactcggcctccttggaggatgtg aagactgcggtcctggggctcctggtcatccttcagaccaagctgtatgccctgcctgcc agccatgccacacgcgtgtacgagacgctggtcagccacattcagctccactacaagcac agctacaccctgcccattgccagcagcatccgtctgcaggccttcgacttcctgctgcag ctgcgggccgactcactgcaccgcctgggcctgcccagcaaagacgggcttgtgaggttc agcccctactgcgtctgtgactgcctggagacagagaggagctccgagaagaaggccggg ggccccctgtccccgcccgccgggccccctggccctgcgcctgcgggccctgctgtgcgc ctcgggtccctgccctactccctgctcttccgtgttctgctgcagtgtctgaagcaggag actgactggaaggtgctgaagctggtgctcagcaaactgcccgagtcgctgcgctataag gtcctcatcttcacctccccatgcagtgtcgaccagctgtccgccgccctctgctccatg ctttcaggtcccaagaccctggagcggctccgaggcactccagaaggcttctccagaacc gacctgcatctcgctgtggttcccgtgctgacagccctgatctcttaccataactacttg gacaaaactagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgt gccagccagtgtgtggtggccctggccgtgtgcagcgtggagatgcccgacgtcatcctc aaggcactgcccgtcctggttgtgaagctcacacacatctcggccacggccagcatggcc atcccgctcctcgagttcctgtccactctggccagactgcctcacctctacaggaacttc gcagcagagcagtatgccagtgtgtttgccatctccctgccgtataccaacccctccaag ttcaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcatcaggtgc cgcctgcccttccggaaggactttgttccttacatcaccaagggtctgcgctccaacgtc ctcctgtctttcgatgacacccccgagaaggacagcttccgagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaactcaaggagagctctgcagccgatgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcaggatccagacctctctcacgagcgccagcttgggg tctgcagacgagaactcgatggcccaggccgacgacaacttgaaaaacctccacctggag ctcacagagacgtgtctggacatgatggccagatatgtgttctccaacttcacggcggtc cccaagaggtcccccgtgggagagttcctcctggctggtggcaggaccaaaacctggctg gttgggaacaagcttgtcaccgtgacgacaagcgtgggtaccgggacccggtcactgcta ggcctggactctggagagctgcagggtggcccggagttgagctctgaccccagcatgcat gtgagacagacaaaggaggcacccgccaagctggagtcccaagctgggcagcaggtgtac cacggagcccgggaccgggtccgctccatgtccgggggccatggccttcgcgtgggtgcc ttggacgctccagcctgctacttccccagcagccccacgtccccgggctcccagaccgct ccagccagccagcccgagaaggcctcagctggcagcccgctcccagcacagaaggagaag acaaacctggctgcttacgtgcccctgctgacccagggctgggcagagatcctggtccgc aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccccttctcc tcggacatcaacagcatgccgctgcaggagctgtccaatgccctcatggccgccgagcgc ttcaaggagcgccgcgacacagccctgtacaagtcgctgtcggtgccggcggccggctca gccaagccatccccgcccccacgctccaacacagtggcctctttctcctccctgtgccag tccaggtgccaaggaaagctgcacaggagcatttcctgggcagattctgcggtggtcctg gaggagggaggtccaggtgaggctggtttgtctgcagagcctcccgagttggaagatttt gaggcgacactgggctccgacgggcgctgtgggcgcagcgacgctttcagcaggtcatct tccacctccagccaggaggagaagtcattccatgccgaggagttgcctcctgggggcatc cccatcgagcgggcggtctcctcggagggctcccgggcctccgtggacctcgccttccag ccctctcagcccctgagcaagtccagctcgtcacctgaactgcagaccctgcaggacatc ctgggggaccccggggacaaggctgaggtcggccggctgagccccgaggccaaggcccgg tcgcagtcagggatcctggacggggaaggtgccgcctggtcagccccgggtgaggaacgc cggggtcggggccctgcccagccagagggccccttgccttccagctgtccccgctccccc agcgggctgcggccccgaggctacaccatctcggattcggccccgtcacgcaggggcaag agggtggagagggatgccttcaagaaccgagcagggacctccaacaccgagaaggtgcca ggcatcaaccccagcttcgtgttcctgcagctctaccactcaccgttctttggtgacgag tccaacaagccaatccttttgcctaacgagtctttcgaacgatcagtgcagctccttgat cagatcccgtcgtacgacacgcacaagatcgcggtcctgtacgtgggagaaggccagagc aacagcgagctcgccatcctgtccaacgagcatggctcctacaggtacacagagttcctc acggggctgggcaagctcatcgagctcaaggactgccagccggacaaggtgtacctgggc ggcctggacgtgtgcggcgaggatggccagttcacctactgctggcacgacgacatcatg caagctgtcttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgctgt gacaagaagcgccacctgggcaacgacttcgtgtccatcgtctacaacgactctggcgag gacttcaagttgggcaccatcaagggccaattcaacttcgtccacgtgattatcacgccc ctggactacgagtgcaacctggtgtctctgcagtgcaggaaagacatggagggccttgtg gataccagcatggccaagatcgtgtctgaccgaaacctgcccttcgtggcccgccagatg gccctgcacgccaatatggcctcgcaggtgcatcatagccgctccaatcccaccgacatt tatccctccaagtggattgccaggctccgccacatcaagcggctgcgccagcggatccgt gaggaagcccactactcaagcgccagcctgcccctgatgcagacacaccctcctggtcat gccaaggctccggcacaggccccggctgagtccacgcccacctatgagacgggccagcgg aaacggctggtctcctctgtggacgacttcactgagttcgtgtga

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