Bos mutus (wild yak): 102268521
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Entry
102268521 CDS
T02919
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00270
Cysteine and methionine metabolism
bom00480
Glutathione metabolism
bom01100
Metabolic pathways
bom01240
Biosynthesis of cofactors
bom04216
Ferroptosis
Module
bom_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102268521 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102268521 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102268521 (GCLC)
Enzymes [BR:
bom01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102268521 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
102268521
NCBI-ProteinID:
XP_070217444
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Position
23:complement(42863050..42908022)
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AA seq
638 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
EKKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPAPFIETFPEDEEATKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKDKEIYEQLLQ
EGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QELFYFRKDICKAGGNAVVDGCGKAAGRAEPAAEEYALMTIDTIINGKEGVFPGLIPVLN
SYLESMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIAKHPDYKQDSVITDQMNY
SLLLKCNQIANESCECPELLGPAFRKVRYSGSKTDSSA
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagacccagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgatgaggtggagtacatgttggtgtcttttgatcat
gaaaagaaaaaagcccaactggtcctgtctggagaggaacttcttgaaactctgcaagaa
aagggggaaaggacgaacccaaaccatccgaccctttggagaccagaatatgggagctac
atgatcgaggggacacccgggcagccgtacggtgggaccatgtctgaattcaacacagtt
gaggacaacatgaggaaacggcgcaaagaagccacatctctcctgggggaaaaccaggcc
ctctgcacgatcacttcctttcccagattaggctgccctgggttcacgctgcccgagttc
aaacccaacccggtggaaggaggagcttccaagtcccttttctttcctgatgaagccatc
aacaagcacccgcgcttcagcacgctcaccaggaacatccggcaccggaggggcgagaaa
gtggtcatcaatgtgcccatctttaaggacaagaacaccccagctccatttatagagact
ttccctgaggacgaggaggccacgaaggcctctaagcccgaccacatttacatggacgcc
atgggcttcgggatgggcaactgctgcctacaggtaacgttccaagcctgcagcatatct
gaggccagatacctttacgatcagttggctaccatctgcccaattgtcatggctttgagt
gctgcgtcgcctttttaccgaggctacgtgtcagacattgattgtcgctggggcgtgatt
tccgcgtctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaac
cactataggatcagtaagtcccgatacgattcgatagacagttacttgtctgagtgtggt
gagaaatacaatgacattgacctgacaaaagacaaagaaatctatgaacagctgttgcag
gaaggcctcgaccacctgctggcccagcacgtggcgcatctcttcatcagagacccgctg
actctgtttgaagagaaaatccacctggatgatgccaacgagtccgaccactttgagaat
attcagtccacaaattggcagacaatgcgattcaagcctcctcctccaaactctgacatt
gggtggagagtggaattccggcccatggaggttcagctgacagacttcgagaactccgcg
tatgtggtgtttgtggtgctgctcaccagggtgatcctgtcctacaaactggactttctc
atcccgctgtccaaggttgatgagaacatgaaggtcgcccagaagcgagatgccgtcctg
caggaactgttttatttcaggaaagacatttgcaaagcaggtggcaatgccgtggtggac
ggctgcggcaaggccgcgggcagggcggagccagcggcggaggagtacgcgctcatgacc
atcgacaccatcatcaacggcaaggaaggcgtgttccccgggctgatccccgtcctgaac
tcctacctggagagcatggaggtggacgtggacaccaggtgcagcattctgaactacctg
aagctcatcaagaagagggcgtccggagaattaatgacagttgccaaatggatgagggag
tttatcgcaaagcatcccgactacaagcaggacagtgtaataactgaccagatgaactat
agccttcttctaaagtgtaatcaaatcgcaaacgaatcgtgtgagtgcccagagttactc
ggaccagcgtttaggaaagtcaggtacagtggaagtaaaaccgactcttccgcttag
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