Bos mutus (wild yak): 102271230
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Entry
102271230 CDS
T02919
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00140
Steroid hormone biosynthesis
bom01100
Metabolic pathways
bom05215
Prostate cancer
Module
bom_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102271230 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
102271230 (SRD5A2)
Enzymes [BR:
bom01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
102271230 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
102271230
NCBI-ProteinID:
XP_005893075
UniProt:
L8IT53
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Position
11:92145650..92193554
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AA seq
254 aa
AA seq
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MSVRCQQSPVLAGSATLAALGALVLYLAEPSGYGKYSENLMPVAIRLPARAAWFLQELPS
FAVPAGILAGQPSSLLGPPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLFRGFVFCM
GNGLLQGYYLVYCAEYPAEWYTDIRFSLGIFLFILGMGINIHSDYILRQLRKPGEIIYRI
PQGGLFTYVSGANFLGEIIEWIGYALASWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFD
DYPKSRRALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgtctgttcgctgccagcagagtccggtgcttgcaggcagtgccactttggccgccctg
ggggcactggtcctgtacctcgcggagccctccggctacgggaagtactcggagaacttg
atgccggtggctatccgtctgcccgcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatactcgccgggcagcccagctctctcctgggtccgcctgcg
actgtgcttctgggcctcttctgcgcacattactttcacaggacatttgtttattcactg
ctcactagagggaggccgtttccagttgtattccttttcagaggctttgtcttctgcatg
ggaaatggactcctccaaggctactatctggtttactgtgctgaataccctgctgagtgg
tacacagacatacggtttagcctgggtatcttcttattcattttgggaatgggaatcaac
attcacagtgactatatattgcgccagctcaggaagcctggagaaatcatctataggatt
ccacaaggtggcttgttcacgtatgtttctggagccaatttcctcggtgagatcattgaa
tggatcggctatgccctggcctcttggtccctcccagcacttgcatttgcatttttctca
ctttgtttccttgggctgcgagcttttcatcatcatagattctacctcaagatgtttgat
gactaccccaagtctcgaagagccctcattccattcatcttttaa
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