Bos mutus (wild yak): 102273144 Help Entry 102273144         CDS       T02919                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism bom  Bos mutus (wild yak) Pathway bom00010   Glycolysis / Gluconeogenesis bom00620   Pyruvate metabolism bom01100   Metabolic pathways bom01200   Carbon metabolism bom01230   Biosynthesis of amino acids bom04910   Insulin signaling pathway bom04930   Type II diabetes mellitus bom04932   Non-alcoholic fatty liver disease bom04950   Maturity onset diabetes of the young Module bom_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate bom_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102273144 (PKLR)    00620 Pyruvate metabolism     102273144 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102273144 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102273144 (PKLR)    04950 Maturity onset diabetes of the young     102273144 (PKLR)    04932 Non-alcoholic fatty liver disease     102273144 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:bom04147]     102273144 (PKLR) Enzymes [BR:bom01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      102273144 (PKLR) Exosome [BR:bom04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    102273144 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C HpcH_HpaI Motif Other DBs NCBI-GeneID:  102273144 NCBI-ProteinID:  XP_014334586 LinkDB All DBs Position 3:complement(19390785..19396034) Genome browser AA seq 468 aa AA seqDB search MPQGPGQLPLKSSLCSGPQYHAESIANIREAVESFANSPLSYRPVAIALDTKGPEIRTGI LQGDPASEVEIVKGSRVLVTVDPEFQTRGDANTVWVDYPNIVRLMPVGGRIYIDDGLISL VVKKIGPEGLETEVENGGVLGSRKGVNLPGIQVDLPGLSEQDVQDLRFGVEHGVDIVFVS FVRKASDVAAVRDALGPEGQGIKIVSKIENHEGVKKFNEILEVSDGIMVARGDLGIEIPA EKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSG ETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKC CAGAIIVLTTTGRSAQLLSRYRPRATVIAVTRSAQAARQAHLCRGVFPVLYREPPEDIWA DDVDRRVQFGIDNGKLCGFLSSGDLVIVVTGWQPGSGHTNIMRVLSVT NT seq 1407 nt NT seq  +upstreamnt  +downstreamnt atgccccaaggtcccggccagcttcccctgaaatcctcactttgttctggtccccagtac cacgctgagtccatcgctaacatccgggaggcggtggagagctttgcaaattctccgctc agctaccgacccgtggccatcgccctggacaccaagggaccagagatacgcactgggatc ctgcaaggggacccggcgtcagaagtggagatagtgaagggctcccgggtgctggtgacc gtggacccagagttccagacccgcggggacgcgaacaccgtgtgggtggactaccccaat atcgtccgactcatgccggtggggggccgcatctacattgacgacgggctcatctcccta gtggtcaagaaaatcggtccagaagggctagagaccgaagtggagaacggcggtgtcctg ggcagtcggaagggcgtgaacttgccaggcatccaggtggacctgcccgggctgtccgaa caagatgtccaggacctgcgcttcggggtggagcatggcgtggacatcgtctttgtctct ttcgtgcggaaagccagcgacgtggctgccgtccgggatgctctggggccggaaggacag ggcatcaagatcgttagcaaaatcgagaaccacgagggcgtaaagaagttcaatgaaatc ctggaggtgagcgacggtattatggtggcacggggtgacctgggcattgagatcccggct gagaaggttttcctggctcagaagatgatgatcggccgttgcaacttggcgggaaagccc gttgtctgtgctacacagatgctggagagcatgatcactaagccccggccaactcgggca gagacaagtgacgtggccaatgctgttctggatggggcagactgcatcatgctgtcaggg gagactgccaaaggcaactttcctgtggaggctgtaaagatgcagcatgcgattgcccgg gaggcagaggctgccgtgtaccaccggcagctctttgaggagctacgccgggcagcacca ctgagccgggatcccacggaggtcaccgctattggtgctgtggaggctgccttcaagtgc tgtgctggtgccatcattgtgctgaccacaactggccgctcagcccagcttctgtcccgg taccgacctcgggcaacagtcattgccgtcacccgctctgctcaggctgcccgccaggcc cacctgtgccgaggagtcttccctgtgctctaccgtgaacctccagaggacatctgggcc gatgatgtggaccgtcgggtccaatttggcatcgacaatggaaagctctgtggcttcctc agttctggggacctggtgattgtggtgacaggctggcaaccaggctctggccataccaac atcatgcgggtgctgagcgtaacctga

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