Bos mutus (wild yak): 102276437
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Entry
102276437 CDS
T02919
Symbol
BRCA2
Name
(RefSeq) breast cancer type 2 susceptibility protein isoform X1
KO
K08775
breast cancer 2 susceptibility protein
Organism
bom
Bos mutus (wild yak)
Pathway
bom03440
Homologous recombination
bom03460
Fanconi anemia pathway
bom05200
Pathways in cancer
bom05212
Pancreatic cancer
bom05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
102276437 (BRCA2)
03460 Fanconi anemia pathway
102276437 (BRCA2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102276437 (BRCA2)
09162 Cancer: specific types
05212 Pancreatic cancer
102276437 (BRCA2)
05224 Breast cancer
102276437 (BRCA2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
bom04121
]
102276437 (BRCA2)
03036 Chromosome and associated proteins [BR:
bom03036
]
102276437 (BRCA2)
03400 DNA repair and recombination proteins [BR:
bom03400
]
102276437 (BRCA2)
Ubiquitin system [BR:
bom04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
102276437 (BRCA2)
Chromosome and associated proteins [BR:
bom03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
102276437 (BRCA2)
DNA repair and recombination proteins [BR:
bom03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
102276437 (BRCA2)
FA (Fanconi anemia) pathway
Downstream FA components
102276437 (BRCA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB1
Tower
Motif
Other DBs
NCBI-GeneID:
102276437
NCBI-ProteinID:
XP_070236543
LinkDB
All DBs
Position
12:complement(28496581..28535792)
Genome browser
AA seq
2917 aa
AA seq
DB search
MPIGCKERPTFFDIFKARCNKADLGPISLNWFEELSSEAPLCNSEPLEESEYKISSNETN
PFKTPQRKPYHQLASTPVIFKEQSLTLPLYQSPLKELHKFRLDSGKDIANSKHKSCCRVK
AKINQANDVISPPPNSSLSESPVVLRCTHVTPQREKSVVCGSLFHTPKLIKGQTPKRISE
SLGAEVDPDMSWSSSLATPPTLSSTVLIVQDEEASAAVFPRDTTAILKTYFSNHDESLKN
NKFIPSGPDSDNKNQTKAESHGLEKMLEDSFRKVNSCKDHFEKSMPNVLEHEVHETVAGI
SEEDSLPVCVSKYKTKKLQKRKTGKGRKNIFHETKTDECEEAKKEMTESKHSFVSETEPN
DSDPLDSNVIKQKPVGNGTDIISREVLPSSVSEWSQLTLSGLNGTQVQKTSLLHISSCDQ
TNSEEDLIGTEKECTNFITLENSLPHISSISKTVKILNKETVVNKTDEGQCLESHEDPTT
VGKQILSDSSPLQDTKKSIFRIRESPEKIFREDFSNNVTDSNLKKEPEDSKSESEIQTIY
SQKEDSVCSSSGDNESWPATTKYTSEALKNTGLISTLKKKTKKFIYVINDKTAYQGLKIQ
KDQESELTNSSAQFEAKPLEAPHTFTNVDSGSLPSSIQKKCSQNDSEEPTLSLTSSFGTV
LRKCFNNESSSSTNKTISQDLYCKETNINKEKWQSFITTETDYVSCLQDKHCEDNPKSQG
VSDIKEKVLPVVCCPELPHSEECNDTVFQFQESFLHDHDNTTILTPSSKDLLSNPVVIPR
GKQSYKMSEKIKSKNCEAGFELTKYISMEDNQETCVLNENSKKAEMLSPEKYITGALPSV
KVQCHQNMNLTVIHKDQEETTLISKRTVNPNSEELSPDSENNYIFQTTSERNIPILGNIK
EVHEADLSCLREPVLKNSVRVTSTDMDGGQAAKVSITKDSVSSNTVHGLIEKNRNSVKQQ
PKMTLGQDSKPDVSLDTDTKSNRNNFCKDKWAGLSDLTSSHSFGNGFRTASNKEIKLSEH
NIKKSKMLFKDIEEHYPASLPWVEIVKSLENQRKGGQPHDRDSQSVDTVCGYVQSGAVVS
DGENSHTTPPVLSLKQDFNSNHNLTPSQKAEITELSTILEESGSQFEFTQFRKPSHILQS
NPFEMPETQMTVLNTTSEEQKDVDLHLTASTPSLSHIDSKKCEGLAGREQKMICLSTTNC
NKSVSGSLTDKGEEFRGFYSARGTKLNVSNEALQKAMKLFSDIEKVSEKTPAEVDPGSFS
SNQCNNSDVSMFKVENYSNDKNLSEENNKCQLILQSNFEMTTSIFVKENTEDFKRNTENK
DNKCIGFVCNLGESDGCASSKNDTVYVHKDESGLPYTDQYNIHLKLSHHFMKEENIPIKE
SLSDLTCLEVMKAEETFNKSNKKEPIANKMRQNIKDFGVFDLSFWTANGKNIRVSKESLN
KVVNFFDEKCTEKELNNFSDSSNSELLSGININKIDISSHEETSMFKNKMLQESSPAGIE
NQILTLQQREKCEFKKIKEPTTLGFHTASGKKVKIAKESLDTVKNLFDETKQDNSEVTDF
IQGAKMLMDREVCKEGLDLACEIVKGTAPKHEEMQNSLEEKELVSEETAMPPRFLSDHLQ
GQTENLHTSHSVSLKVKVHENMEEETAKSPITCYTNHSTCSAIENSALAFYTGHGRKISV
SQASLLEAQKWLREGELNDQPEKINSSKIICLKEYTRDYVGNPSCGNSSNSITENDKSLS
EKQDSTSLNNSMPNSYSYSDFCHSSEGFNKSENLSKNKIDNSGIEPVVKNVKGRKNTSFS
EVIPTIREANINPQAVDKDSCVLKLVTKFSPCKNKKTAVEVALSNSNNFETEPPAYSTAS
DQIAFVSRETTVRERFTDNCRNIYTKQNTETKSGTDQTKTVTDSHKALGDSEDVIFPNSP
DNEEHNMHSHDVSPDIQSEPILQHDQSISGLEKVSEIPLRHVDLKTSDRCKFNMGKHPRS
VSSMNACGIFNTASGKSVQVSDSALQKARQVFSKSEDRAKQFFSRVSFKSNDEHSDIFTR
KENTMTHNPPNLLSSAFSGFSTASGKHVPVSESALCKVKGMFEEFDLIGTEYSLQHSPTS
RQDVSKILPVSCTDKRNPEHSVSSKMEKAYNKEFKLSNNYNIESASSENNHSIKVSSYLS
EFKQDQQQSVLGTRVSHTDNIHLLGEKQTLPKYIKKEIGKTETFPDLVKTNTEICSTDSK
DPENYFETEAVEIAKAFMEDGELTDSEFPSHAKHSPFTCQKNKETVLSNSRIEKRRGDAL
VTVGEPPIKRNLLNEFDRTIENQGKSLKASKSTPDGTMKDRRLFMHHISLEPVTCGPSCI
TTERQEIQTPNFTAPGQEFLSKSHFYEHLTLGKSSSNLSISGQPLGKVPDPRNEKRRHSI
TIGKPMKVFVPPFKTKSHIHRDEQFVGKNTNLEENKQQKNIDEHGSGDSENNVNNCEIHQ
TTTILFTKGEEEPLDSITNLQNARDIQDMRIRKKQRQCIFPQPGSLYLAKTSTMPRIPLR
EAVEGRIPSACSHKQLYMYGVSKHCVKINSKNAEAFQFHTQDYFGKESLWTGKGIQLADG
GWLIPSNDGKAGKEEFYRALCDTPGVDPKLISRVWVYNHYRWIIWKLAAMEFAFPKKFAN
RCLNPERVLLQLKYRYDVEIDRSKRSAIKKIMERDDTAAKTLVLCVSEIISLSTDISEPS
SNKTSSVDTTKVAVVQLTDGWYAIKAQVDPPLSALLKNGRLTVGQKIVIHGAELVGSPDA
CTPLEAPESLMLKISANSTRPACWYAKLGFSPDPRPLPLPLSSLFSDGGNVGCVDIIIQR
AYPIQWMEKTSTGLYIFRNEREEEKEATKYAEAQQKKLEALFTKIQAEFEDHEENVTEQC
IPSRALTRQQVRALQDGAELYEAVKNAPDPSYLEVRQ
NT seq
8754 nt
NT seq
+upstream
nt +downstream
nt
atgccgattggatgcaaagagaggccaactttttttgacatttttaaggcgcgatgcaac
aaagcagatttaggaccaataagccttaattggtttgaagaactttcttcagaagctcca
ctctgtaattctgaacctttagaagaatcagaatataaaatcagcagtaatgaaacaaac
ccatttaaaacaccacaaaggaaaccttatcatcagttggcttcaactcctgtaatattc
aaagagcaaagtctaactctgccactgtaccaatctcctttaaaggaattacataaattc
agattggattcaggaaaggatattgccaacagtaaacataaaagttgttgcagggtgaag
gctaaaatcaatcaagcaaatgatgttatcagcccacctccaaattcctctcttagtgaa
agtcctgttgttctgcgatgtacacatgtaacaccacaaagagaaaagtcagtggtatgt
ggaagtttatttcatacaccaaagctcataaagggtcagacaccgaaacgtatttctgaa
agtttaggagctgaggtggatcctgatatgtcttggtcaagttctttggccacaccacca
acacttagttctactgtgctcatagtccaagatgaggaagcatctgcagctgtgtttcct
agggatactactgctattttgaaaacatatttttctaaccatgatgaaagtctgaaaaat
aataagtttatcccttctgggccagacagtgacaacaaaaatcaaacaaaagctgaaagt
catggattggagaaaatgttagaggattcatttcgtaaagtaaatagctgcaaagaccat
tttgaaaagtcaatgccaaatgtcctagaacatgaagtacatgaaacagttgcaggtatc
tctgaagaagatagtttgccagtatgtgtttctaaatataaaacaaaaaagctacaaaaa
agaaaaactggcaagggtaggaaaaatattttccatgaaacaaaaacagatgaatgtgaa
gaagctaaaaaggaaatgacagaaagtaaacattcatttgtatctgaaacagaaccaaat
gacagtgatccattagattcaaatgtaataaagcaaaagcccgttgggaatggaactgac
ataatctccagggaagttttaccatcttcagtctctgaatggtctcagctcacactctcg
ggtctaaatggaacccaggtgcagaaaacgtctctactgcatatttcctcttgtgaccaa
actaattcagaagaagacctcataggcacagagaaagagtgtaccaacttcattacttta
gaaaattctttgccacatatttcaagcatatcaaaaacagtgaagatattaaataaggaa
acagtggtaaacaagacagatgaagggcagtgtcttgaatctcatgaagatcccactact
gtgggaaagcaaatactaagtgactcttctccacttcaggacaccaaaaaatctatcttc
aggataagagaatctcctgaaaagatatttagagaagatttctcaaataatgtgactgat
tcaaacttgaaaaaagaaccagaagactctaaaagtgaatcagaaatacaaactatttac
tcacagaaagaggattctgtatgttcaagttcaggggataatgagagctggccagccact
accaaatacacttcagaagctttgaagaacacaggtttaatatccactttgaaaaagaaa
acaaaaaagtttatttatgttataaatgataaaacagcttatcaaggactgaaaatacag
aaagaccaagaatcagaactaactaactcttcagcccaatttgaagcaaagcctttggag
gcaccacatacatttacaaatgttgattcaggttcattgccttcttctatccaaaaaaaa
tgttcacagaatgattctgaagaaccaactttgtctttaaccagctcttttgggacagtt
ctgagaaaatgttttaataatgaaagcagttcttctactaataaaacaatatctcaggat
ctttattgtaaagaaacaaacattaataaggaaaaatggcagtcatttataaccacagaa
actgattatgtatcatgcttgcaggacaagcattgtgaagataatccaaaaagccaaggt
gtttcagatataaaggaaaaagtcttgcctgtagtatgttgccctgaattgccacattca
gaggaatgtaatgatactgtcttccaattccaggaaagttttttacatgaccatgataat
accaccattttaactcctagctccaaggatcttctgtcaaatccagttgttattcctaga
ggaaaacaatcatataaaatgtcagagaaaataaaatctaagaattgtgaagcaggtttt
gaattaactaaatatatttccatggaagacaatcaagaaacatgtgttttaaatgaaaat
tctaagaaagctgagatgttgtcacctgaaaaatatataacaggagcattaccttctgtg
aaagtacaatgccaccaaaatatgaatctcacagtcatccataaagaccaggaagaaact
actttaatttcaaaaagaactgtcaacccaaactctgaagaactctccccagacagtgaa
aataattatatctttcaaacaactagtgaaaggaatattcctattttaggaaacattaag
gaagttcatgaggcagacctcagttgtttaagagaacctgttctcaaaaactctgttaga
gtaacaagtacagatatggatggtggacaagcagccaaagtgtccattacaaaagattct
gtctcatcaaatacagtccatggtcttatagagaagaatagaaatagcgtaaagcaacaa
ccaaagatgactctaggtcaagattcaaagccagatgtgtccctagatacagatacaaaa
tcaaacagaaataacttttgcaaggacaaatgggcaggactctcagatttgacttcaagt
cacagttttggaaatggcttcagaacagcttctaataaagagataaaactctctgaacac
aacattaagaaaagcaaaatgctcttcaaggatattgaagaacattatcctgctagctta
ccttgggttgaaattgtaaaatcattagaaaatcaaaggaaaggaggccaacctcatgat
cgtgattcacagtcagttgatacagtgtgtgggtatgtgcagagtggtgcagttgtttct
gatggtgaaaacagtcacacaactcctccagttttatctttaaagcaagacttcaattca
aaccataatttaacacccagccagaaggcagaaattacagaactttctacaatattggaa
gaatcaggaagtcagtttgaatttacacagttcagaaaaccaagccacattttacagagt
aatccatttgaaatgcctgaaacccagatgactgtcttgaataccacttctgaggagcag
aaagatgttgatcttcatctcacagccagtaccccatctctcagtcacatagatagcaag
aaatgtgaaggtttagctggacgtgagcaaaagatgatctgcttgtcaacaaccaactgt
aacaaaagtgtttctggttctttaacagataaaggtgaagagtttaggggcttttattca
gcccgtggcacaaaactgaatgtttctaatgaagcattgcagaaagccatgaaactgttc
agtgacatcgagaaagttagtgagaaaactcctgcagaagtagatccaggaagtttctct
tcaaatcagtgtaacaattctgatgtttctatgtttaaggtagaaaattatagcaatgat
aaaaatttaagtgaggaaaataataaatgccaactgatactacaaagtaactttgaaatg
accaccagcatttttgtcaaagaaaatactgaagatttcaagagaaatactgaaaacaaa
gataacaaatgtattggttttgtttgtaatttaggagaatctgatggctgtgcttcaagt
aaaaatgatacagtttatgttcataaagacgaaagtggcttaccatatactgatcaatac
aacatacatctgaaattatctcatcactttatgaaagaggaaaacattccaattaaagaa
agtttgtcagatttaacttgtttggaagttatgaaagctgaagaaacatttaataagtca
aataaaaaggagccaattgctaataagatgaggcaaaatataaaagattttggtgttttt
gatttgtccttttggactgcaaatgggaaaaacataagggtctctaaggagtctttaaat
aaagttgtaaatttctttgatgaaaaatgtacagaaaaagaattgaataatttttcagat
tcctcaaattctgaattactttctggcataaatatcaacaaaatagacatttcaagtcat
gaggaaaccagtatgttcaaaaacaaaatgttgcaagaaagcagcccagctggtattgaa
aatcaaatactgacactgcagcaaagagaaaaatgtgaattcaaaaagatcaaagaacca
accacgttgggtttccatacagctagtgggaaaaaagtaaaaattgccaaagagtctttg
gacacagtgaaaaatctttttgatgaaacaaagcaagacaatagtgaagtgactgatttt
atccaaggggcaaaaatgctaatggacagagaggtttgtaaggaagggcttgacttagca
tgtgagatagttaaaggaactgccccaaagcatgaagagatgcagaattctctagaggag
aaagagcttgtttctgaggagactgccatgccacccaggttcttaagtgatcatttacaa
ggacaaactgaaaatctccacacatcacatagtgtctctctgaaagttaaagtacatgaa
aatatggaagaagaaacagcaaaaagtcctataacgtgttacacaaaccattccacttgt
tcagccattgaaaactcagctttagcgttttacacaggacatggtagaaaaatttctgtg
agtcaggcttcactacttgaagcccagaaatggcttagagaaggagaattgaatgatcaa
ccagaaaaaataaattcctccaaaattatatgtttaaaggaatatactagggattacgta
ggaaatccttcatgtggaaacagttcaaacagtataactgaaaatgacaaaagcctctct
gaaaagcaagattcaacttccttaaacaacagcatgcctaacagctattcatattctgat
ttttgtcattccagtgagggatttaataaatcagagaatctctcaaaaaataaaattgat
aattccggtattgagccagtagtaaagaatgtcaaaggcaggaaaaacactagtttttct
gaagtaatacccaccataagagaagcaaacataaacccacaagctgtagacaaagatagt
tgtgttctgaaacttgtgactaagttttcaccatgcaaaaataaaaagacagctgttgaa
gtggccttatctaattcaaataattttgagaccgaaccacctgcatacagtacagcaagt
gatcaaatagcctttgtttcacgtgaaacaacagtcagagagaggtttacagacaactgc
aggaacatatatactaagcaaaacactgagacgaaatcaggcactgaccaaacgaaaact
gtgacagattctcataaggcattgggtgactcagaggatgttattttccctaactctcca
gataatgaagaacataatatgcattcacatgatgtttctcctgacattcaaagtgaaccg
attttacaacatgaccaaagtatttctggattggagaaagtttctgagataccacttcgt
catgttgatttgaaaacttctgatagatgtaaatttaacatgggaaagcatcccaggtct
gtctcttctatgaatgcttgtgggatttttaacacagcaagtggaaaatctgtccaagtg
tcagattctgcattacaaaaagcgagacaggtattttctaagtcagaagaccgtgccaag
cagttcttttccagagtatcatttaaaagtaatgacgagcattcagacatattcacaaga
aaagaaaatactatgacacataaccccccaaatttactatcatctgctttctctggattt
agtacagcaagtggaaaacacgttccagtttctgagagtgccttatgcaaagttaaggga
atgtttgaagaattcgatttaatcggaactgaatatagtctccagcattcacctacttct
aggcaagatgtatcaaagatacttcctgtctcttgtactgataaaagaaacccagaacac
tctgtaagctccaaaatggaaaaagcctacaataaagaatttaaattatcaaacaactat
aacattgaaagtgcttcatcagaaaataatcactctattaaagtttcttcgtatctctct
gaatttaagcaagaccaacaacagtcagtattaggaaccagagtatcacacactgacaac
attcatcttttgggggaaaagcaaactttgcctaaatatataaaaaaggaaattgggaaa
acggaaacttttcctgatcttgtgaaaacaaatacagaaatttgttctactgactccaaa
gacccagagaactattttgaaacagaagcagtagagattgctaaagcttttatggaagat
ggtgagctgacagattctgaatttccaagtcatgcgaaacactctccttttacatgccaa
aaaaataaggaaacggttttgtcaaattcaagaatagaaaaaagaagaggagatgcactt
gtcacagtcggagaacccccaatcaaacgaaacttgttaaatgaatttgacaggacaata
gaaaatcaaggaaaatccttaaaggcttcaaaaagcactccagatggcacaatgaaagat
agaaggttgtttatgcatcacatttctttagagccagttacctgtggaccctcttgcata
actacggaacgtcaagaaatacagaccccaaatttcactgcacctggtcaagaattttta
tctaagtctcacttttatgaacacctgactttgggaaagtcttcaagcaatttatcaatt
tcagggcagccacttggcaaggttcctgacccaaggaatgagaaaaggagacactcgata
actataggcaaacccatgaaagtctttgtcccaccttttaaaactaaatcacacattcac
agagatgagcagtttgttggcaagaatactaatttggaggaaaacaaacaacaaaaaaac
atagatgagcatggctctggtgacagtgaaaacaatgttaacaactgtgaaattcatcaa
acaacaactatacttttcaccaagggtgaagaagaacctttagattcaattacaaatctt
cagaatgccagagatatacaggatatgcgaattagaaagaaacaaaggcaatgtattttt
ccacagccaggcagtctgtatcttgcaaaaacatccactatgcctagaatccctctcaga
gaggcagtagaaggccgaattccctctgcgtgttctcacaaacagctatatatgtatggt
gtttctaaacactgtgtaaaaattaacagcaaaaatgcagaggcttttcagtttcacact
caggattattttggtaaggaaagtttatggactggaaagggaatacagttggctgatggt
ggatggctcataccctccaatgatggaaaggctggaaaagaagaattttatagagctctg
tgtgacaccccaggtgtggatccaaagcttatttctagagtttgggtctataatcattat
agatggattatatggaaactagcagctatggaatttgcctttcctaagaaatttgctaat
agatgcctgaacccagaaagggtacttcttcaactaaaatacagatatgatgtggaaatc
gatagaagcaaaagatcagcgataaaaaagataatggaaagggatgacacagctgcaaaa
acacttgttctctgtgtttctgaaataatttcattaagcacagatatatctgaaccttct
agcaataagactagcagtgtggataccacaaaggtggccgttgtccaacttacagatgga
tggtatgctattaaggcccaggtggaccctcccctctcagctctcctaaagaacggtaga
ctgactgtgggtcagaagatcgtaattcacggagcagagctggtgggctctcctgatgcc
tgtacacctcttgaagccccagaatctcttatgttaaagatttctgctaatagcactcga
cctgcttgctggtatgccaaacttggattctcccctgatcccagacctcttcctcttccc
ttgtcatcactcttcagcgatggaggaaatgttggttgcgttgatataattattcagaga
gcataccctatacagtggatggagaagacatcaactggattatacatatttcgcaatgaa
agagaagaagaaaaggaagcaacaaaatatgcagaagctcagcaaaagaagctggaagcc
ctgttcactaaaattcaagcagaatttgaagaccatgaagaaaatgtgacagaacaatgt
ataccatcacgtgcactaacaagacagcaagtccgtgctctgcaagatggtgcagaactt
tatgaagctgtgaagaacgcgccagacccaagttaccttgaggtgagacagtaa
DBGET
integrated database retrieval system
