Bos mutus (wild yak): 102277585 Help Entry 102277585         CDS       T02919                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism bom  Bos mutus (wild yak) Pathway bom01521   EGFR tyrosine kinase inhibitor resistance bom01522   Endocrine resistance bom04010   MAPK signaling pathway bom04012   ErbB signaling pathway bom04014   Ras signaling pathway bom04062   Chemokine signaling pathway bom04068   FoxO signaling pathway bom04072   Phospholipase D signaling pathway bom04150   mTOR signaling pathway bom04151   PI3K-Akt signaling pathway bom04510   Focal adhesion bom04540   Gap junction bom04630   JAK-STAT signaling pathway bom04650   Natural killer cell mediated cytotoxicity bom04660   T cell receptor signaling pathway bom04662   B cell receptor signaling pathway bom04664   Fc epsilon RI signaling pathway bom04714   Thermogenesis bom04722   Neurotrophin signaling pathway bom04810   Regulation of actin cytoskeleton bom04910   Insulin signaling pathway bom04912   GnRH signaling pathway bom04915   Estrogen signaling pathway bom04917   Prolactin signaling pathway bom04926   Relaxin signaling pathway bom04935   Growth hormone synthesis, secretion and action bom05034   Alcoholism bom05160   Hepatitis C bom05161   Hepatitis B bom05163   Human cytomegalovirus infection bom05165   Human papillomavirus infection bom05200   Pathways in cancer bom05205   Proteoglycans in cancer bom05206   MicroRNAs in cancer bom05207   Chemical carcinogenesis - receptor activation bom05208   Chemical carcinogenesis - reactive oxygen species bom05210   Colorectal cancer bom05211   Renal cell carcinoma bom05213   Endometrial cancer bom05214   Glioma bom05215   Prostate cancer bom05220   Chronic myeloid leukemia bom05221   Acute myeloid leukemia bom05223   Non-small cell lung cancer bom05224   Breast cancer bom05225   Hepatocellular carcinoma bom05226   Gastric cancer bom05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bom00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102277585 (SOS2)    04012 ErbB signaling pathway     102277585 (SOS2)    04014 Ras signaling pathway     102277585 (SOS2)    04630 JAK-STAT signaling pathway     102277585 (SOS2)    04068 FoxO signaling pathway     102277585 (SOS2)    04072 Phospholipase D signaling pathway     102277585 (SOS2)    04151 PI3K-Akt signaling pathway     102277585 (SOS2)    04150 mTOR signaling pathway     102277585 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102277585 (SOS2)    04540 Gap junction     102277585 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102277585 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     102277585 (SOS2)    04660 T cell receptor signaling pathway     102277585 (SOS2)    04662 B cell receptor signaling pathway     102277585 (SOS2)    04664 Fc epsilon RI signaling pathway     102277585 (SOS2)    04062 Chemokine signaling pathway     102277585 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     102277585 (SOS2)    04912 GnRH signaling pathway     102277585 (SOS2)    04915 Estrogen signaling pathway     102277585 (SOS2)    04917 Prolactin signaling pathway     102277585 (SOS2)    04926 Relaxin signaling pathway     102277585 (SOS2)    04935 Growth hormone synthesis, secretion and action     102277585 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     102277585 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     102277585 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102277585 (SOS2)    05206 MicroRNAs in cancer     102277585 (SOS2)    05205 Proteoglycans in cancer     102277585 (SOS2)    05207 Chemical carcinogenesis - receptor activation     102277585 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     102277585 (SOS2)    05231 Choline metabolism in cancer     102277585 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     102277585 (SOS2)    05225 Hepatocellular carcinoma     102277585 (SOS2)    05226 Gastric cancer     102277585 (SOS2)    05214 Glioma     102277585 (SOS2)    05221 Acute myeloid leukemia     102277585 (SOS2)    05220 Chronic myeloid leukemia     102277585 (SOS2)    05211 Renal cell carcinoma     102277585 (SOS2)    05215 Prostate cancer     102277585 (SOS2)    05213 Endometrial cancer     102277585 (SOS2)    05224 Breast cancer     102277585 (SOS2)    05223 Non-small cell lung cancer     102277585 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     102277585 (SOS2)    05160 Hepatitis C     102277585 (SOS2)    05163 Human cytomegalovirus infection     102277585 (SOS2)    05165 Human papillomavirus infection     102277585 (SOS2)   09165 Substance dependence    05034 Alcoholism     102277585 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102277585 (SOS2)    01522 Endocrine resistance     102277585 (SOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH PH_19 Motif Other DBs NCBI-GeneID:  102277585 NCBI-ProteinID:  XP_070234210 LinkDB All DBs Position 10:65060045..65165951 Genome browser AA seq 1332 aa AA seqDB search MQQAPQPYEFYSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPKFNENFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKI RSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG CSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSVIYAAKSAEEKNNWMAALI SLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA LEKGEQPISTDLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLESFISSVR GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGCASEKEFTDYLFNKSLEIEPRNCK QPPRFPRKSAFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS EEPLIPPPLPPRKKFDQDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPAGPFDGPL HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPN TPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPVY RLPLLENAETPQ NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccttacgagttctacagcgaagagaacagtccgaaatggcgg ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct aatgaagagtctctctattacattgaagagctgatttttcagctgcttaataaattatgc atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaaagaaga aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac aaagtggactaccatgtatccctgtatattgtggctgtgctggagtatatctcagctgat attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcaacaa gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac ataggcttggtttctctttgtgaagatgaacctagttcttcaggcgagttaaactactat gaccttgttagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc ataaaagtgtttcgagaagcttttctttctgacagaaagctgtttaaaccttctgatatt gaaaagattttcagtaacattttagatatacatgaattgactgtgaaacttttaggttta attgaagacacagttgaaatgactgatgaaagtagccctcatcccttagctggcagctgt tttgaagatctggcagaggagcaagcatttgatccttatgaaacattatcccaggatatt ctttcaccaaagtttaatgaaaattttagtaagttgatggccagacctgcagtggctcta cactttcagtccatcgctgatggttttaaagaggcagttcgttatgtccttccacgcctt atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaaata cgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatgaat ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat gaatttattatggaaggcccattgacaagaattggtgctaaacatgaacggcatattttt ctctttgatggcttaatgattagctgcaaacccaatcacagccagtcacgccttccagga tgcagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt gataaagaagatacttgtgagtgcaaacatgcttttgaattagtatccaaagatgaaaac agcgtaatatatgctgctaagtctgccgaagagaaaaataattggatggcagcacttatt tcccttcagtatcgtagtactcttgatcgaatgctagattcagtattattgaaggaagaa aatgaacaaccattgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct gaggaaaacattgtttttgaagacaacttgcagagtagaagtggaatccccattattaaa ggaggaactgtggtgaaattaattgaaaggctaacatatcatatgtacgcagatcccaat tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattactaagc ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggcg ttagaaaaaggcgaacagcccatcagtacagaccttaaaaggtttcgcaaggaatacgtc caaccagtacaacttagagtcttaaatgtgtttcggcactgggttgaacaccatttttat gactttgaaagagacttggagctgcttgaaagactagaatccttcatttcaagtgtaaga gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaaaaaacaa gctcaggcaaatggtataagccataatattacctttgaaagtccacctccaccaattgaa tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata gaaattgcacgtcagctgacccttttggaatctgatctctacaggaaagttcaaccttct gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta aaaatgattcgccacaccacaaatctcaccctctggtttgaaaaatgcattgtggaggca gaaaattttgaggaacgagtggcaatactgagtagaattatagaaattctgcaagttttt caagatttgaataatttcaatggtgtattggagatcgtcagtgcagtaaattcagtatca gtctatagactagatcatacctttgaggcgttgcaggaaagaaaaaggaaaattttggat gacgctgtggaattaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatc aatccaccctgtgtgcctttttttggaatatatttaacaaatatactgaagactgaagaa gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg aaagtagctgaaattactggagaaattcagcagtatcaaaatcaaccttactgtttacgg atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggatgtgcttctgaa aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaattgcaaa cagccacctcgatttcctaggaaatcagctttctccttaaaatctcctggaataaggcct aatacaggccgacatggctctacctcaggtactttgcgaggtcacccaacaccattagaa agagaaccgtgtaaaataagctttagtcggattgctgaaacggagcttgaatcaacagtg tcagcaccaacctctccaaatacaccgtctaccccaccagtgtctgcttcttcagacctt agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca gtcctcttgcctcattcaaagtctttcttcagttcgtgtggtagtttacataagctaagt gaagagccactgattcctcctccacttccacctcgaaaaaaatttgatcaggatgcttca aattccaagggaactatgaaatctgatgatgacccccctgctattccaccaagacaacct cctcctccaaaggtaaaacccagagttcctgctcccgctggtccatttgacgggcctctg cacagtccacctccaccgccgccaagagaccctcttcctgatacccctccaccggttcca cttcggcctccagaacactttataaactgtccgtttacccttcagccacctccactggga catcttcacagagatccagactggttcagagacgttagtacgtgtccaaattctccgaac actcctcctagcacaccctctccaagggtacctcgtcgatgctatgtgctcagttctagt caaaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct catctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccagtgtat agactgcctttgttagaaaatgcagaaactcctcaatga

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