Bos mutus (wild yak): 102285300
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Entry
102285300 CDS
T02919
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00562
Inositol phosphate metabolism
bom01100
Metabolic pathways
bom01521
EGFR tyrosine kinase inhibitor resistance
bom04012
ErbB signaling pathway
bom04014
Ras signaling pathway
bom04020
Calcium signaling pathway
bom04062
Chemokine signaling pathway
bom04064
NF-kappa B signaling pathway
bom04066
HIF-1 signaling pathway
bom04070
Phosphatidylinositol signaling system
bom04072
Phospholipase D signaling pathway
bom04360
Axon guidance
bom04370
VEGF signaling pathway
bom04380
Osteoclast differentiation
bom04611
Platelet activation
bom04613
Neutrophil extracellular trap formation
bom04625
C-type lectin receptor signaling pathway
bom04650
Natural killer cell mediated cytotoxicity
bom04662
B cell receptor signaling pathway
bom04664
Fc epsilon RI signaling pathway
bom04666
Fc gamma R-mediated phagocytosis
bom04670
Leukocyte transendothelial migration
bom04722
Neurotrophin signaling pathway
bom04750
Inflammatory mediator regulation of TRP channels
bom04919
Thyroid hormone signaling pathway
bom04933
AGE-RAGE signaling pathway in diabetic complications
bom04935
Growth hormone synthesis, secretion and action
bom05167
Kaposi sarcoma-associated herpesvirus infection
bom05169
Epstein-Barr virus infection
bom05170
Human immunodeficiency virus 1 infection
bom05171
Coronavirus disease - COVID-19
bom05200
Pathways in cancer
bom05205
Proteoglycans in cancer
bom05206
MicroRNAs in cancer
bom05214
Glioma
bom05223
Non-small cell lung cancer
bom05225
Hepatocellular carcinoma
Module
bom_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
102285300 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
102285300 (PLCG2)
04014 Ras signaling pathway
102285300 (PLCG2)
04370 VEGF signaling pathway
102285300 (PLCG2)
04064 NF-kappa B signaling pathway
102285300 (PLCG2)
04066 HIF-1 signaling pathway
102285300 (PLCG2)
04020 Calcium signaling pathway
102285300 (PLCG2)
04070 Phosphatidylinositol signaling system
102285300 (PLCG2)
04072 Phospholipase D signaling pathway
102285300 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102285300 (PLCG2)
04613 Neutrophil extracellular trap formation
102285300 (PLCG2)
04625 C-type lectin receptor signaling pathway
102285300 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
102285300 (PLCG2)
04662 B cell receptor signaling pathway
102285300 (PLCG2)
04664 Fc epsilon RI signaling pathway
102285300 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
102285300 (PLCG2)
04670 Leukocyte transendothelial migration
102285300 (PLCG2)
04062 Chemokine signaling pathway
102285300 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
102285300 (PLCG2)
04919 Thyroid hormone signaling pathway
102285300 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
102285300 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102285300 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
102285300 (PLCG2)
04380 Osteoclast differentiation
102285300 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102285300 (PLCG2)
05206 MicroRNAs in cancer
102285300 (PLCG2)
05205 Proteoglycans in cancer
102285300 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102285300 (PLCG2)
05214 Glioma
102285300 (PLCG2)
05223 Non-small cell lung cancer
102285300 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102285300 (PLCG2)
05171 Coronavirus disease - COVID-19
102285300 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
102285300 (PLCG2)
05169 Epstein-Barr virus infection
102285300 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102285300 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102285300 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bom04131
]
102285300 (PLCG2)
Enzymes [BR:
bom01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
102285300 (PLCG2)
Membrane trafficking [BR:
bom04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
102285300 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
102285300 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
102285300
NCBI-ProteinID:
XP_070244755
LinkDB
All DBs
Position
18:complement(54164783..54324766)
Genome browser
AA seq
1262 aa
AA seq
DB search
MANVDTLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEG
FLDIMEIKEIRPGKSSKDFERAKAVRQKEECCFTVLYGSQFILSTLSLAADSKEDAAKWL
SGLKILHQEVMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSAKFL
KDKFLEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFLLGNTDRPDASAVHL
HDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWD
EKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDCWDG
PDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARVFKE
VFGDLLLTKPKEASADQLPSPSQLRGKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGELHM
WDPIDQKWTRHYCAVADAKLSFSDDIEQTVEEELPLDIPPTELHFGEKWFHKKVEKRTSA
EKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTMKYYLTD
NLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDMLMRI
PRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKH
ALYRKMKLRYPVTPELLERYNTERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYRAK
QSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISPTEGEEVDKQIIEDN
PLGSLCRGILNLNIYNVVKAPHGKNQKPFVFILEPKKQGDPPVEFATDSVEELFEWFQSI
REITWKMDAKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVETKA
DSIVRQKPSDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQM
NHALFSLNGRTGYVLQPESMRAEKYDPMPPESQRKIQMTLTVKVLGARHLPKPGRSIACP
FVEVEICGAEYDSNKFKTTVVNDNGLSPVWTPTQEKVTFEIYDPNLAFLRFVVYEEDMFS
DPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQL
RRRQEELNNQLFLYDTHQNLRSATRDALVREFNVNENQLQLYQEKCNRRLREKRVSNSKF
YS
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
atggccaacgtggacaccctcccggagtacgagaagagtcagatcaagcgggccctggag
ctgggcaccgtcatgaccgtgttcagcttccgcaagtccaccccggagcggaggaccgtc
caggtgatcatggagacgcggcaggtggcctggagcaagacggccgacaagatcgagggc
ttcctggacatcatggagataaaggagatccggccggggaagagctccaaggatttcgag
cgcgcgaaagcggtccgccagaaggaagaatgctgcttcaccgtcctgtacggctcccag
tttatcctcagcacgctcagcctggcagccgactcgaaggaggatgccgctaagtggctg
tctggcctgaagatcttacaccaggaagtgatgagcgcgtccacccccaccatcatcgag
agctggctgagaaagcagatttattctgtggatcaaaccaggagaaacagcatcagcctc
cgggagttgaagaccatcttgcctctggtcaacttcaaagtgagcagtgccaagttcctc
aaagataagttcctggaaataggcgcacacaaagatgaactcagctttgaacagttccat
ctcttctataaaaaacttatgtttgaacagcaaaaatcgatccttgacgaattcaaaaag
gattcctccgtgttcctcttgggcaacaccgaccggccagacgcctctgctgtccacctg
cacgacttccagcggtttctcttgcatgaacagcaggagctttgggctcaggatctgaac
aaagtccgtgagcggatgacgaagtttattgacgacaccatgagggaaactgctgaaccc
ttcctgtttgtggatgagttcctcacgtacctgttttcccgggagaacagcatctgggac
gaaaagtacgacgtggtggacatgcaggacatgaacaaccccttgtctcattactggatc
tcctcgtctcacaacacgtacctcacgggggaccagctgcggagcgagtcgtccacggag
gcctacatccgctgcctgcggatgggctgccgctgcatcgagctggactgctgggacggg
cccgacggcaagcccatcatctaccacggctggacgcggaccaccaagatcaagttcgac
gacgttgtgcaggccatcaaagaccacgcctttgtcacctccagcttccccgtgatcctg
tccatcgaggagcactgctgtgtggagcagcagcgccacatggccagggtgttcaaggaa
gtgtttggagacctgctgctgaccaaacccaaggaggccagtgccgaccagctgccgtcg
cccagccagctgcgcgggaagatcatcatcaagcataagaagctgggcccccgcggtgac
gtggatgtcaacatggaggacaagaaggacgagcacaagcagcagggcgaactgcacatg
tgggaccccatcgaccagaaatggactcggcactactgtgccgttgctgatgccaagctg
tccttcagcgatgacattgaacagactgtggaagaggagctgcccctggatataccccca
acagagctgcattttggggagaagtggttccacaagaaggtggagaagaggacaagtgcc
gagaagctgctgcaggaatactgtgccgagacagggggcaaggatgggaccttcttggtg
cgggagagtgagaccttccccaacgactacaccttgtccttctggcggtcgggccgcgtg
cagcactgccggatccgctccaccatggagggcgggaccatgaagtactacctgaccgac
aacctcatgttcaccagcatctacgctctcatccagcactaccgcgagacacacctgcgc
tgcgccgagttcgagctccggctgaccgaccccgtgcccaaccccaacccgcacgagtcc
aagccgtggtactacgatgggctgagccgtggagaagcggaggacatgctgatgcggatc
ccccgggatggggccttcctgatccggaagcgggaaggtaccgactcctatgccatcacc
ttcagggccaggggcaaggtgaagcactgtcgcatcaaccgagacggccggcacttcgtg
ctgggcacctccgcctacttcgagagccttgtggagctggtcagctactacgagaagcac
gcactctaccggaagatgaaactgcgctaccccgtgacccccgagctcctggagcgctac
aacacggaaagagatataaactccctctacgatgtcagcaggatgtatgtggatcccagt
gaaatcaatccttcaatgcctcagagaaccgtgaaagctctgtatgactacagggccaag
cagagtgacgagctgagcttttgccgcggtgccctcatccacaacgtctccaaggagcct
gggggctggtggaaaggagactatgggaccagaatccagcagtacttcccgtccaattac
gtcgaggacatttcaccaacagaaggggaggaggtggataagcagattattgaagacaat
cccttagggtccctttgcagaggaatcctgaatctcaacatctataatgttgtaaaagcc
ccacatgggaagaaccagaagcctttcgtctttatcttggagcccaagaagcagggcgac
cctccggtagagtttgccacggacagcgtggaggagctgtttgagtggttccagagcatc
cgggagatcacctggaagatggacgccaaggagaacaacatgaagtactgggagaagaac
cagtccatcgccatcgagctctcggacctggtcgtctactgcaagccaaccagcaagacc
aaggacaacctcgaaaaccctgacttccgagaaatccgctccttcgtggagacgaaggct
gacagtatcgtcagacagaagcccagcgatctcctgaaatacaatcaaaagggcctgacc
cgtgtgtaccccaaaggacagcgggtggactcgtccaactatgaccccttccgcctctgg
ctgtgcggctcccagatggtggcactcaatttccagactccagataagtacatgcagatg
aaccacgccctgttctccctcaacgggcggacgggctacgtcctgcagcctgagagcatg
agggcggagaagtacgaccccatgccacccgagtcccagaggaagatccagatgaccctg
acggtcaaggtgctgggggcccgtcacctccccaagcccggccgcagcatcgcgtgcccc
ttcgtggaggtggagatatgcggagcggagtacgacagcaacaagtttaagacgacggtt
gtgaatgacaatggcctcagccctgtttggaccccaacgcaggagaaggtgacgtttgag
atttatgaccccaaccttgcgtttctgcgctttgtggtttatgaggaagatatgttcagc
gatcccaactttctggcccatgccacgtaccccattaaaggaatcaagtcaggatttaga
tctgttcctctgaagaacggctacagtgaagacattgagctggcgtccctcctggttttc
tgtgagatgcggccagtcctggagagcgaagaggagctgtattcctcctgccgccagctg
cggaggcggcaagaagaactgaacaaccagctctttctgtacgacacccaccagaacctg
cgcagtgccacccgcgatgccctggtcagagaattcaacgtcaacgagaaccagctgcag
ctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaacagcaagttt
tactcatag
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