Bos mutus (wild yak): 102285642 Help Entry 102285642         CDS       T02919                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04961   Endocrine and other factor-regulated calcium reabsorption bom04962   Vasopressin-regulated water reabsorption bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05207   Chemical carcinogenesis - receptor activation bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102285642 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102285642 (ADCY9)    04371 Apelin signaling pathway     102285642 (ADCY9)    04020 Calcium signaling pathway     102285642 (ADCY9)    04072 Phospholipase D signaling pathway     102285642 (ADCY9)    04024 cAMP signaling pathway     102285642 (ADCY9)    04022 cGMP-PKG signaling pathway     102285642 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102285642 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     102285642 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102285642 (ADCY9)    04062 Chemokine signaling pathway     102285642 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     102285642 (ADCY9)    04923 Regulation of lipolysis in adipocytes     102285642 (ADCY9)    04912 GnRH signaling pathway     102285642 (ADCY9)    04913 Ovarian steroidogenesis     102285642 (ADCY9)    04915 Estrogen signaling pathway     102285642 (ADCY9)    04914 Progesterone-mediated oocyte maturation     102285642 (ADCY9)    04921 Oxytocin signaling pathway     102285642 (ADCY9)    04926 Relaxin signaling pathway     102285642 (ADCY9)    04935 Growth hormone synthesis, secretion and action     102285642 (ADCY9)    04918 Thyroid hormone synthesis     102285642 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     102285642 (ADCY9)    04916 Melanogenesis     102285642 (ADCY9)    04925 Aldosterone synthesis and secretion     102285642 (ADCY9)    04927 Cortisol synthesis and secretion     102285642 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102285642 (ADCY9)    04270 Vascular smooth muscle contraction     102285642 (ADCY9)   09154 Digestive system    04970 Salivary secretion     102285642 (ADCY9)    04971 Gastric acid secretion     102285642 (ADCY9)    04972 Pancreatic secretion     102285642 (ADCY9)    04976 Bile secretion     102285642 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102285642 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     102285642 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     102285642 (ADCY9)    04727 GABAergic synapse     102285642 (ADCY9)    04725 Cholinergic synapse     102285642 (ADCY9)    04723 Retrograde endocannabinoid signaling     102285642 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102285642 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     102285642 (ADCY9)    04213 Longevity regulating pathway - multiple species     102285642 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     102285642 (ADCY9)    04714 Thermogenesis     102285642 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102285642 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     102285642 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102285642 (ADCY9)    05163 Human cytomegalovirus infection     102285642 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     102285642 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102285642 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102285642 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102285642 (ADCY9) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102285642 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom Motif Other DBs NCBI-GeneID:  102285642 NCBI-ProteinID:  XP_005901380 UniProt:  L8IB07 LinkDB All DBs Position Un AA seq 1354 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVRINPKQPSSNSHPKHCKYSISSSCSSSGDS GGVPRRMGAGGRLRRRKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDNFNHTRAARPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLILGVAYSVLFETFGYHFQDEACFASPGAEALHWELLSRALLHLCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVLDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFTPKPEAGAEGGAVQNGCQEEPKN SAKASGGPSSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDPELERAYRTSYQEEVVKSSPVRTF ASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSVR MVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTGS AVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYISLCPDSSTVISHLDAVQNFSST RKLCNASLSHDGRSPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRT KIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGK ECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILF EFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDT TGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPKCTDSGLVPQHQLSIS PDIRVQVDGSIGRSPTDEIASLVPSVQNPDQVSPGSENNAQTRDAHPSAKRPWKEPVRAE ERCRFGKAIEKSDCEEVGMEEANELTKLNVSERA NT seq 4065 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagctgtgac tccagcggagacagcaacagcgtgcgggtcaggatcaaccccaagcagccgtcctccaac agccacccgaagcactgcaagtacagcatctcctccagctgcagcagctccggggactcc ggaggggtcccccgaagaatgggcgcgggaggccgcctgcgcaggaggaagaagctgccc cagctgttcgaacgggcctccagccggtggtgggaccccaagtttgactctgtgaacctg gaggaggcttgcatggagcgttgcttcccgcagacccagcgccgcttccggtatgcgctc ttctacatcggcttcgcctgccttctctggagcatctattttggggtccacatgaaatcg aaactgattgtcatggtagcccctgctctgtgcttcctcgtggtgtgtgtgggctttttt ctgtttaccttcaccaagttgtacgcccgccattacgtgtggacttcgctggttctcacc ctcctggtattcgccctgaccctggctgcccagtttcaggttttgacgcccctctcagga cgagttgacaacttcaatcatactcgggctgccaggcccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgattttgggagtggcctattctgttctttttgagacctttggc taccacttccaagatgaagcctgctttgcctcacctggagcggaggctctgcactgggag ctgctgagccgggccctgctccacctctgcatccacgccatcgggatccacctgttcatc atgtcccaggtgagatccaggagcaccttcctcaaggtgggccagtctattatgcacgga aaggatctggaagtggaaaaggccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaaacagggggatgaggagagtgagaattctgtcaaaagg cacgccacctccagccccaagaacaggaagaagaagtcttccatccagaaagcccctatc gccttccgcccgtttaagatgcagcagatcgaagaagtcagtattttatttgcagatatt gtgggcttcaccaagatgagtgccaataagtctgcccacgccctggtgggtctcctcaac gatctgttcggccgctttgaccggttgtgtgaggagaccaaatgtgagaaaatcagcacc ttgggagactgctactattgtgtggctgggtgtcctgagccaagggccgaccatgcctac tgctgcatcgagatggggttgggcatgataagagccattgaacagttctgccaagagaag aaagagatggtgaacatgcgcgttggggttcacacagggaccgtcctgtgtggcatcttg ggcatgaggaggtttaaatttgatgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggctggcaaggttcacatttccgaggccaccgcaaaatacctagat gaccggtacgaaatggaggatgggaaagttactgaacgccttggccagagtgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcac tgcagctgttcagaggccttactttctggctttgaggtccttgacggctcgcgggtgtcc tcaggccctaggggacaggggacagcgtcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccatcgtgcggaatcacgttcactcccaag ccagaagctggtgcagaaggtggagcggtccagaacggctgtcaggaggagcccaagaac agcgccaaggcctccggaggacccagctccaaaacgcaaaatggacttctgagtcctccc ccggaggagaagctcaccaacagtcagacctccctgtgcgagatcttacaggagaagggc aggtgggcaggcgtgagcctggatcagtcggctctccttccgctgaggttcaagaacatc cgggagaaaacggatgcccactttgtcgacgttatcaaggaagacagcctgatgaaagac tacttttttaagccgcccattaaccagttcagcttgaacttcctggatccggagctcgag cgggcctacaggaccagctatcaagaagaggttgtaaagagctctcccgtgaggactttc gccagtgccaccttcagctccctcctggatgtgcttctgtcgacaacagtgtttctgatt ctctccatcacctgcttcctgaggtacggggccgcctccacgccgcccccgccggccgcc ctggcagtcttcggagcggccctgctgctggagatcctgtccctcgtggtctctgtcagg atggtgttcttcctggaggacgtgatgacgtgcacgaagcgcctgctggagtggatagcc ggctggctcccgcgccatttcatcggggccatcctggtgtctctccccgccctggcagtg tattcacacgtcacctctgaatttgaaacaaacatacactccaccatgttcacgggctcg gccgtgctgaccgccgtggtgcaatactgcaacttctgccagctcagctcctggatgcgg tcctccctggccactgtcgtcggggccgggcccctgctgctgctgctctacatctccctg tgcccggacagttccactgtaatttcacaccttgatgcagtacagaatttcagctccacc aggaagctgtgcaacgcctcgctgtctcacgacggcaggagcccagccagcctgatcggc caggaggtgattctcgtcttcttcctcctgctcctgttggtctggttcctgaaccgagag ttcgaagtcagctaccgcctgcactaccacggggacgtggaggcggacctgcaccgcacc aagatccagagcatgagggaccaggccgactggctgctgcggaacatcatcccctaccac gtggccgagcagctcaaggtgtcccagacctactccaagaaccacgacagcggaggcgtc atcttcgccagcatcgtcaacttcagcgagttctacgaggagaactacgagggcggcaag gagtgctacagggtcctcaacgagctgatcggggactttgacgagctcctgagcaagccg gactacagcagcatcgagaagatcaagaccatcggggccacgtacatggccgcgtccggg ctgaacgccacgcagtgccgcgacggcagccacccgcaggagcacctgcagatcctcttc gagttcgccaaggagatgatgcgtgtggtggacgacttcaacaacaacatgctgtggttc aacttcaagctcagggtgggcttcaaccacgggcccctgacggcgggcgtcatcggcacc accaagctgctgtacgacatctggggggacacggtcaacatcgccagcaggatggacacc acgggggtggagtgccgcatccaggtcagcgaggagagctaccgcgtcctgagcaagatg ggctacgagttcgactaccgagggacggtgaatgtcaagggcaaaggccaaatgaagacc tacctgtaccccaagtgcacagacagtgggttggtgccacagcaccagctgtccatctca cccgacatccgggtccaggtggatggcagcatcggacgctcccccacagacgagatagcc agcctggtgccttccgttcagaacccggaccaggtgtccccgggttccgagaacaacgcc cagaccagggacgctcacccgtctgctaagagaccctggaaggagccagtcagagccgag gaaaggtgtcggttcggcaaagccatagagaaaagcgactgtgaagaagtggggatggag gaagccaacgaactcacgaagctcaacgtctcagagagggcgtga

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