Bos mutus (wild yak): 102286537
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Entry
102286537 CDS
T02919
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00790
Folate biosynthesis
bom01100
Metabolic pathways
bom01240
Biosynthesis of cofactors
bom01523
Antifolate resistance
bom04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102286537 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102286537 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102286537 (FPGS)
Enzymes [BR:
bom01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
102286537 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
102286537
NCBI-ProteinID:
XP_005908507
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Position
11:complement(8417855..8429562)
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AA seq
585 aa
AA seq
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MSRARCHALFLAAVSPRGATTRVAVRRGLSAWPVLQEPDMEYQDAVRTLNTLQTNANYLE
MVKRKRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGL
KTGFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLT
LMAFHVFLQEKVDLAVLEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQ
KGGIFKSGVPAFTVLQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQ
RSNAALALQVARCWLQQKGYQDAGELKASRPSLPGQLPLAPVFQPTPRMQQGLRHTEWPG
RTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHRCERPDSGSEVRVLLFNSTGDRDSA
ALLKLLQPCQFDYAIFCPNLAEMASTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHEEQV
SPDPWSTPSQEQDGPASLLLAPHPPHTHSASSLVFSCISHALQWITQGRDPLFQPPSPPR
GLLAHPVADSGAMVLQEAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1758 nt
NT seq
+upstream
nt +downstream
nt
atgtctcgggcacgctgccacgctctcttcctggcagcggtttctccgcgtggtgcaaca
accagggtcgcagtgcggcgagggttgagcgcgtggcctgtgctgcaggagccagacatg
gagtatcaggatgccgtgcgtacactcaacaccctgcagaccaatgctaactacttggag
atggtgaagcgtaagcggggtgacccccagacacagctggaagccatgaagctgtacttg
gcacggagtgggctgcaggtggaggacttggaccagctgaacattatccacatcactgga
accaaggggaagggctccacgtgtgccttcactgaacgtatcctccgaagctatggcctg
aagacggggttctttagctctccccacctggtgcaggtgcgtgagcggatccgcatcaat
gggcagcccataagctccgagctcttcaccaagcacttctggcgcctctaccaccggctg
gaggagaccaaggacgacagcagctgtgtctccatgcccggctacttccgcttcctcacg
ctgatggccttccacgtcttcctccaagagaaggtagacctggcagtgttggaagtaggc
attggcggggcttacgactgcaccaacatcatcaggaagcctgtggtgtgtgggatcacc
tctcttggcatcgaccacactggccttctgggggacacgatggagaagatcgcatggcag
aaagggggcatttttaagagtggcgtccctgccttcaccgtgctccagcctgacgagccg
ctggcggtgctaagggacagggctcagcagatctcatgtcccctctacctgtgcccacca
ctacaagccctggaggaaggggggccaccactgaccctgggcctggagggagagcaccag
cggtccaatgctgccctggccttgcaggtggcccgctgctggctgcagcagaaaggttac
caggatgctggggagctgaaggcatccaggcccagcctcccggggcagctgcccctggca
cctgtgttccagcccacgccccgcatgcagcaggggcttcggcacacggaatggccaggt
cggacgcagttgctgcggcgcgggcctcttacctggtacctggacggcgcgcacaccacc
agcagcatgcaagcctgtgtgcgctggttccgccaggcgctgcaccgctgcgagaggcca
gacagcggttccgaggtgcgcgtcttgctcttcaactccactggggaccgggattccgcg
gccctgctgaagctgctgcagccctgccagtttgactatgccattttctgccctaacctg
gcagagatggcatcaacagacaatgcagaccaacagaacttcacagtgacactggaccag
gtgctgctccgctgcctcgcccaccaacagcactggagtcgcctgcatgaggagcaggtc
agcccggacccctggagcacccccagccaggagcaggatgggcctgcatctctgctgctg
gcgcctcacccaccccacacccacagtgccagctccctcgtcttcagctgcatctcccat
gccttgcagtggatcacccaaggccgggaccctctctttcagccgcccagtcccccacgg
ggcctcctcgcccaccctgtggcagacagtggggccatggtactccaagaggctgccgcc
attcacgtgctggtcacaggcagcctgcacctggtgggcggtgtcctgaagctgctggag
ccctccctgtcccagtag
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