Bos mutus (wild yak): 102287065
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Entry
102287065 CDS
T02919
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00260
Glycine, serine and threonine metabolism
bom00630
Glyoxylate and dicarboxylate metabolism
bom00670
One carbon pool by folate
bom01100
Metabolic pathways
bom01200
Carbon metabolism
bom01230
Biosynthesis of amino acids
bom01240
Biosynthesis of cofactors
bom01523
Antifolate resistance
bom04981
Folate transport and metabolism
Module
bom_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102287065 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102287065 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102287065 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102287065 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102287065 (SHMT2)
Enzymes [BR:
bom01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102287065 (SHMT2)
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
102287065
NCBI-ProteinID:
XP_005901762
UniProt:
L8I966
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Position
5:16112184..16120100
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AA seq
504 aa
AA seq
DB search
MLSFSFIWATRPLRRCGQLVGMAVRCQHSEAAQTQTGEASKGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFKPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQILKNAQA
MANALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKTTKLQDFKSFLLKDPETSH
QLADLRQRVEQFARAFPMPGFDDH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccttctcttttatttgggcgactcggcctctgcggagatgtggtcagctggtt
gggatggccgtacggtgccagcacagtgaggcggcccagactcagactggagaagcaagc
aagggctggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctg
cggagagagaaggacaggcagtgtcgaggcctggagctcattgcttcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacggaggagcagaggtagtggatgagatagagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgctcagtggggagtcaatgtccaaccc
tactccggatccccagccaatctggctgcctacacagcccttctgcagcctcacgaccga
atcatggggctggacttgcccgatgggggccatctcacccacggctacatgtctgatgtc
aagcggatctcagctacatctatcttcttcgagtctatgccttataagctgaacccccaa
accggcctcattgactatgaccagctggcactcactgctcggctcttcaaaccacgactc
atcatagctggtaccagtgcctatgctcgtctcattgactacgcccgcatgagagaagtg
tgtgacgaggtcaaggcacacctcttggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacccttcaagcacgcggatattgtcaccacgaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggggtgcaggctgtggac
cccaaaactggccgagagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcctgcacccccatgttccgggagtactccctgcagattctgaagaacgctcaggcc
atggctaatgccctgctggagcgaggctactccctggtgtctggtggcactgacaaccac
ctagtgctggtagaccttcggccaaagggcctggacggagctcgagcagaacgggtgttg
gaacttgtatccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcacc
cctgggggcctgaggctgggggccccagccctgacttctcgagggttccttgaagatgac
ttccggaaagttgtaggctttatagatgaaggtgtcaacattggcttggaagtgaagagc
aagaccaccaaactccaggatttcaaatctttcctgctcaaagacccagaaacaagtcat
cagctggccgaccttaggcaacgggtggagcagttcgccagggccttccccatgcctggt
tttgatgatcactga
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