Bosea sp. NBC_00550: NWE53_10125
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Entry
NWE53_10125 CDS
T09927
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bow
Bosea sp. NBC_00550
Pathway
bow00300
Lysine biosynthesis
bow00550
Peptidoglycan biosynthesis
bow01100
Metabolic pathways
bow01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bow00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NWE53_10125
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NWE53_10125
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NWE53_10125
Enzymes [BR:
bow01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NWE53_10125
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UZF94499
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Position
complement(2123470..2124894)
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AA seq
474 aa
AA seq
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MSAPLWTGEKLIAALGARPEGAVPPVVTGASIDTRTLVPGDVFFAIKGEARDGHDFVKGA
LDKGAALAVIDEEHAAEFAGAGALAIVPDVLKAMEQAGTARRAELKAGIVAVTGSVGKTG
TKEALRLVLSRQGKTHAPVASYNNHWGVPLTLCRTPADIAYGVYEIGMNSPGEIVPLARM
VRPQVAIITTIQPVHLAAFASLEGIAEEKAGVFWELEKGGTAIVNADIPQSELLRDIAKS
GPAGRIITFGESPDADVRLISCALKPDLSVVEARVFGEPVTYRLGSPGKHIVLNSLGVLA
VVHALGADLALAALALGDLRPPAGRGARQILQARGGAITLLDESYNGNPASMRAAIENLG
RLPVEGRGRRIAVLGDMLELGPSGGDLHRGLAEPLVANTIDQVFACGPLMKGLYESLPSA
MRGAYAPGASELEPLVLDAIRAGDVVTVKGSLGSRMGPIVKAILARFPAMPAED
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccccgctctggaccggtgagaagctgatcgcggcgctgggcgcgcgacccgaa
ggcgccgtgccgcctgtcgtgaccggcgcctcgatcgacacccggacgctcgtgccgggc
gatgtcttcttcgccatcaagggtgaggcccgcgacgggcatgacttcgtcaagggcgcg
ctcgacaagggcgcggcgctcgccgtcatcgacgaggagcacgcggcggagttcgccggg
gccggcgcgctcgccatcgtgcccgacgtgctgaaggcgatggagcaggccggcaccgcg
cgccgggccgaactcaaggccggcatcgtcgccgtcactggctcggtcggcaagaccggc
accaaggaggcgctgcgcctcgtgctctcgcggcagggcaagacccatgcgccggtcgcc
tcctacaacaaccattggggcgtgcctctcacgctctgccgcacgcctgccgatatcgcc
tatggcgtctacgagatcgggatgaacagccccggcgagatcgtcccgctggcgcggatg
gtgcgcccgcaggtcgcgatcatcaccacgatccagccggtgcatctcgccgccttcgct
tcgctggaggggatcgccgaggagaaggccggcgtcttctgggaacttgaaaaaggcggc
acggccatcgtcaacgccgacatcccgcaatcggagctgctgcgcgatatcgccaagtcc
gggccggccgggcggatcatcaccttcggcgaaagcccggatgccgatgtccggctgatc
tcctgcgcgctcaagccggacctgtccgtggtcgaggcccgcgtcttcggcgagcccgtc
acctatcgcctcggcagcccgggcaagcatatcgtgctgaactcgctcggcgtgctcgcc
gtcgtccatgcgctcggtgccgatctcgcgctggccgcgctcgcgctcggcgacctcagg
ccgccggccgggcgcggggcgcggcagatcctgcaggcgcggggcggcgcgatcacgctg
ctcgacgagagctacaacggcaaccccgcctcgatgcgcgccgcgatcgagaatctcggt
cgcttgccggtggaagggcgcggccggcgcatcgccgtgctcggcgacatgctggagctc
ggaccgagcggcggcgacctccatcgcggtctcgccgagcctctcgtggctaacacgatc
gaccaggtcttcgcctgtggcccgctgatgaaagggctctatgagagcttgccttccgcc
atgcggggggcttatgcccccggggcgagcgaactggagccgctcgtgctcgatgcgatc
cgcgccggcgatgtcgtcacggtcaagggttcgctcggctcgcgcatggggccgatcgtc
aaggcgatcctcgcgcgcttccccgccatgcctgccgaagactga
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