KEGG   Brevibacillus parabrevis: PSE45_14515
Entry
PSE45_14515       CDS       T08846                                 
Name
(GenBank) non-ribosomal peptide synthase/polyketide synthase
  KO
K16124  tyrocidine synthetase III
Organism
bpab  Brevibacillus parabrevis
Pathway
bpab01054  Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:bpab00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01054 Nonribosomal peptide structures
    PSE45_14515
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:bpab01008]
    PSE45_14515
Polyketide biosynthesis proteins [BR:bpab01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   Tyrocidine synthetase
    PSE45_14515
SSDB
Motif
Pfam: Condensation AMP-binding PP-binding AMP-binding_C Thioesterase Abhydrolase_3 Antitox_RHH
Other DBs
NCBI-ProteinID: WDV92885
LinkDB
Position
complement(3045518..3064978)
AA seq 6486 aa
MKKQENIAKIYPLTPLQEGMLFHAVTDTGSSAYCLQMSATIEGDFHLPLFEKSLNKLVEN
YEVLRTAFVYQNMQRPRQVVFKERKVTVPCENIAHLPSAEQDAYIQAYTKQHHTFDLTKD
NLMKAAIFQTAENKYRLVWAFHHIIVDGWTLGVLLHKLLTYYAALRKGEPIPREATKPYS
EYIKWLDKQNKDEALAYWQNYLAGYDHQAAFPKKKLGTEASRYEHVEAMFTIAPEKTQQL
IQIANQNQATMSSVFQALWGILASTYKNADDVVFGSVVSGRPPQIQGIESMVGLFINTIP
TRVQTNKQQTFSELLQTVQKQALASATYDFAPLYEIQSTTVLKQELIDHLVTFENYPDHS
MKHLEESLGFQFTVESGDEQTSYDLNVVVALAPSNELYVKLSYNAAVYDSSFVNRIEGHL
RTVIDQVIGNPHVHLHEIGIITEEEKQQLLVAYNDTAAEYPRDKTIFELIAEQASRTPAK
AAAVCGEDTLTYQELMERSAQLANALREKGIASGSIVSIMAEHSLELIVAIMAVLRSGAA
YLPIDPEYPQDRIQYLLDDSQTTLLLTQSHLQPNIQFAGSVLYLDDRSLYEGGSTSFAPE
SKPDDLAYMIYTSGSTGNPKGAMITHQGLVNYIWWANKVYVQGEAVDFPLYSSISFDLTV
TSIFTPLLSGNTIHVYRGADKVQVILDIIKDNKVGIIKLTPTHLKLIEHIDGKASSIRRF
IVGGENLPTKLAKQIYDHFGENVQIFNEYGPTETVVGCMIYLYDPQTTTQESVPIGVPAD
NVQLYLLDASMQPVPVGSLGEMYIAGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTGD
LAKWLPDGNMEYAGRMDYQVKIRGHRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLY
AYLVSERELTVAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKVERKKLPKPAGAVVTG
TAYAAPQNEIEAKLAEIWQQVLGISQVGIHDDFFDLGGHSLKAMTVVFQVSKALEVELPV
KALFEHPTVAELARFLSRSEKTEYTAIQPVAAQEFYPVSSAQKRMYILQQFEGNGISYNI
SGAILLEGKLDYARFASAVQQLAERHEALRTSFHRIDGEPVQKVHEEVEVPLFMLEAPED
QAEKIMREFVRPFDLGVAPLMRTGLLKLGKDRHLFLLDMHHIISDGVSSQILLREFAELY
QGADLQPLSLQYKDFAAWQNELFQTEAYKKQEQHWLNTFADEIPLLNLPTDYPRPSVQSF
AGDLVLFAAGKELLERLQQVGAETGTTLYMILLAAYNVLLSKYTGQEDIIVGTPVAGRSH
ADVENIMGIFVNTLALRNQPASSKTFAQFLQEVKQNALAAYDHQDYPFEELVEKLAVQRD
ISRNPLFDTLFSLENANQQSLAIAELTASPYELFNKISKFDLALNASESPADIQFQLTFA
TKLFKKETVERMARHYLEILRWISEQPTASLADIDMMTEAEKRTLLLNVNDTFVERTAAT
ALHQLVEEQAARTPDEVAVVYEEYALTYRELNARANQLARLLRSHGTGPDTLIGIMVDRS
PGMVVGMLAVLKAGGAYTPIDPSYPPERIQYMLSDSQAPILLTQRHLQELAAYQGEIIDV
DEEAIYTGADTNLDNVAGKDDLAYVIYTSGSTGNPKGVMISHQAICNHMLWMRETFPLTT
EDAVLQKTPFSFDASVWEFYLPLITGGQLVLAKPDGHRDIAYMTRLIRDEKITTLQMVPS
LLDLVMTDPGWSACTSLQRVFCGGEALTPALVSRFYETQQAQLINLYGPTETTIDATYWP
CPRQQEYSAIPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTKAS
FVDNPFEPGGTMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVK
AVVVMARQDGKGQNSLYAYVVAEQDIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANG
KVDRKALPQPEDAAASAAVYVAPRNEWEAKLAAIWESVLGVEPIGVHDHFFELGGHSLKA
MHVISLLQRSFQVDVPLKVLFESPTIAGLAPLVAAARKGTYTAIPPVEKQEYYPVSAAQK
RMFILQQMEGAGISYNMPGFMYLDGKLDTERLQQALKSLVQRHESLRTSFHSVQGETVQR
VHDDVELAISFGEATEAETRQIAERFIQPFDLGTAPLLRAGLIKLAPERHLFMLDLHHIV
VDGVSIGLLIEEFAQLYHGEELPALRIQYKDFAKWQQDWFQTEEFAAQEAYWLNTFTGEI
PVLNLPTDYPRPSVKSFAGDRFVFGSGTALPKQLHQLAQETGTTLYMVLLAAYNVLLSKY
SRQEDIIVGAPTAGRSHAETESIVGMFVNTLALRNEPAGGKTFRDFLAEVKINTLGAFEH
QDYPLDELVDKLDMQRDLSRNPLFDTVFILQNMEQKPFEMEQLTITPYVAEVKQAKFDLS
LEAYEENAEIIFSLDYSTKLFSRETIEKIATHFIQILRAVIAEPEMPLSEITMLTEAEKQ
RLLVDFNGAHKDFPQNKTLQALFEEQAEKSPQATAVEISGQPLSYQELNERANQLAATLR
ERGVQPDQPVGIMANRSVEMVVGILAILKAGGAYVPIDPEYPEERVAYMLTDCQARLVLT
QKHLGAKLGSSVTAECLYLDDESNYGVHRSNLQPINTASDLAYIIYTSGTTGKPKGVMVE
HRGIVNNVLWKKAEYQLKVGDRSLLSLSFAFDAFVLSFFTPVLSGATVVLAEDEEAKDPV
SLKKLIAASRCTLMTGVPSLFQAILECSTPADIRPLQTVTLGGEKITAQLVEKCKQLNPD
LVIVNEYGPTESSVVATWQRLAGPDAAITIGRPIANTSLYIVNQYHQLQPIGVVGEICIG
GRGLARGYWNKPALTEEKFVSHPFAAGERMYKTGDLGKWLPDGTIEYIGRIDEQVKVRGY
RIEIGEIESALLAAEKLTAAVVVVYEDQLGQSALAAYFTADEQLDVTKLWSHLSKRLPSY
MIPAHFVQLDQLPLTPNGKVDKKALPKPEGKPVTEAQYVAPTNAVESKLAEIWERVLGVS
GIGILDNFFQIGGHSLKAMAVAAQVHREYQVELPLKVLFAQPTIKALAQYVATSGKETYV
PIEPAPLQEYYPVSSAQKRMYVLRQFADTGTVYNMPSALYIEGDLERKRFEAAIHGLVER
HESLRTSFHTVNGEPVQRVHEHVELNVQYAEVTEAQVEPTVESFVQAFDLTKAPLLRVGL
FKLAAKRHLFLLDMHHIISDGVSAGIIMEEFSKLYRGEELPALSVHYKDFAVWQSELFQS
DVYTEHENYWLNAFSGDIPVLNLPADFSRPLTQSFEGDCVSFQADKALLDDLHKLAQESQ
STLFMVLLAAYNVLLAKYSGQEDIVVGTPIAGRSHADIENVLGMFVNTLALRNYPVETKH
FQAFLEEVKQNTLQAYAHQDYPFEALVEKLDIQRDLSRNPLFDTMFILQNLDQKAYELDG
LKLEAYPAQAGNAKFDLTLEAHEDETGIHFALVYSTKLFQRESIERMAGHFLQVLRQVVA
DQATALREISLLSEEERRIVTVDFNNTFAAYPRDLTIQELFEQQAARTPEHAAVVMDGQM
LTYRELNEKANQLAHVLRQNGVGKESIVGLLADRSLEMITGIMGILKAGGAYLGLDPEHP
SERLAYMLEDGGVKVVLVQKHLLPLVGEGLTPIVLEEESLHREDCGNPAIVNGASDLAYV
MYTSGSTGKPKGVMVEHRNVTRLVTHTNYVQVRESDRMIQTGAIGFDAMTFEIFGALLHG
ASLYLVSKDVLLDAEKLGSFLRTNQITTMWLTSPLFNQLSQDNPAMFDSLRALIVGGEAL
SPKHINRVKSALPDLEIWNGYGPTENTTFSTCYLIEQHFEEQIPIGKPIANSTAYIVDGN
NQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGETMYRTGDLARWLPDGTI
EYLGRIDQQVKIRGYRIELGEIETVLSQQAQVKEAVVAVIEEANGQKALCAYFVPEQAVD
AAELREAMSKQLPGYMVPAYYVQMEKLPLTANGKVDRRALPQPSGERTTGSAFVAAQNDT
EAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAMNVITQVHKTFQVELPLKALFATPTIH
ELAAHIAESAFEQFETIQPVEPAAFYPVSFAQKRMYILHQFEGSGISYNVPSVLVLEGKL
DYDRFAAAIQSLVRRHESLRTSFHSVNGEPLQRVHPDVELPVRLLEATEDQSESLIQELI
QPFDLEIAPLFRVNLIKLGAERHLFFMDMHHIISDGVSLAVIVEEIASLYAGKQLSDLRI
QYKDFAVWQTKLAQSDRFQKQEDFWTRTFAGEIPLLNLPHDYPRPSVQSFDGDTVALGTG
HHLLEQLRKLAAETGTTLFMVLLAAYHVLLSKYAGQEEIVVGTPIAGRSHADVERIVGMF
VNTLALKNTAAGSLSFRAFLEDVKQNALHAFEHQDYPFEHLVEKLQVRRDLSRNPLFDTM
FSLGLAESAEGEVADLKVSPYPVNGHIAKFDLSLDAMEKQDGLLVQFSYCTKLFAKETVD
RLAAHYVQLLQTITADPDIELARISVLSKAETEHMLHSFLATKTAYPTDKTFQKLFEEQV
EKTPNEIAVLFGNEQLTYQELNAKANQLARVLRRKGVKPESTVGILVDRSLYMVIGMLAV
LKAGGTFVPIDPDYPLERQAFMLEDSEAKLLLTLQKMNSQVAFPYETFYLDTETVDQEET
GNLEHVAQPENAAYIIYTSGTTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPVRLLQMAS
FAFDVSTGDFARALLTGGQLVICPNEVKMDPASLYEIIRRHEITIFEATPALIMPLMHYV
YENELDMSQMKLLILGADSCPAEDFKTLLARFGQKMRIINSYGVTEACIDTSYYEETDVT
AIRSGTVPIGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVP
NPFAPGERLYRTGDLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAV
VVAREDHGQEKELCAYVVADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKVD
RRSLPAPDVTMLRTTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALGGHSLRAMRV
ISSMHNEYQVDIPLRILFEKPTIQELAAFIEETAKGNVFSIEPVQKQAYYPVSSAQKRMY
ILDQFEGVGISYNMPSTMLIEGKLERTRVEAAFQRLIARHESLRTSFAVVNGEPVQNIHE
DVPFALAYSEVTEQEARELVSSLVQPFDLEVAPLLRVSLLKIGEDRYVLFTDMHHSISDG
VSSGILLAEWVQLYQGDVLPELRIQYKDFAVWQQEFSQSTAFHKQEAYWLQTFADDIPVL
NLPNDFTRPSTQSFAGDQYTIGAGKALTEGLHQLAQATGTTLYMVLLAAYNVLLAKYAGQ
EDIIVGTPITGRSHADLEPIVGMFVNTLAMRNKPQREKTFSEFLQEVKQNALDAYGHQDY
PFEELVEKLAIARDLSRNPLFDTVFTFQNSTEEVMTLPECTLAPFMTDETGQHAKFDLTF
SATEEREEMTIGVEYSTSLFTRETMERFSRHFLTIAASIVQNPHIRLGEIDMLLPEEKQQ
ILAGFNDTAVSYALDKTLHQLFEEQVDKTPDQAALLFSEQSLTYSELNERANRLARVLRA
KGVGPDRLVAIMAERSPEMVIGILGILKAGGAYVPVDPGYPQERIQYLLEDSNAALLLSQ
AHLLPLLAQVSSELPECLDLNAELDAGLSGSNLPAVNQPTDLAYVIYTSGTTGKPKGVMI
PHQGIVNCLQWRRDEYGFGPSDKALQVFSFAFDGFVASLFAPLLGGATCVLPQEAAAKDP
VALKKLMAATEVTHYYGVPSLFQAILDCSTTTDFNQLRCVTLGGEKLPVQLVQKTKEKHP
AIEINNEYGPTENSVVTTISRSIEAGQAITIGRPLANVQVYIVDEQHHLQPIGVVGELCI
GGAGLARGYLNKPELTAEKFVANPFRPGERMYKTGDLVKWRTDGTIEYIGRADEQVKVRG
YRIEIGEIESAVLAYQGIDQAVVVARDDDATAGSYLCAYFVAATAVSVSGLRSHLAKELP
AYMIPSYFVELDQLPLSANGKVDRKALPKPQQSDATTREYVAPRNATEQQLAAIWQEVLG
VEPIGITDQFFELGGHSLKATLLIAKVYEYMQIELPLNLIFQYPTIEKVADFITHKRFES
RYGTAILLNQETARNVFCFTPIGAQSVYYQKLAAEIQGVSLYSFDFIQDDNRMEQYIAAI
TAIDPSGPYTLMGYSSGGNLAFEVAKELEERGYGVTDIILFDSYWKDKAIERTVAETEND
IAQLFAEIGENTEMFNMTQEDFQLYAANEFVKQSFVRKTVSYVMFHNNLVNTGMTTAAIH
LIQSELEADEEAPVAAKWNESAWANATQRLLTYSGHGIHSRMLAGDYASQNASILQNILQ
ELFILK
NT seq 19461 nt   +upstreamnt  +downstreamnt
atgaaaaagcaggaaaacatcgcaaaaatttacccgctaaccccattgcaagagggtatg
ttgtttcacgctgtcacagacacgggcagcagcgcctattgcctccagatgtctgcaacg
atcgagggcgattttcacctgccgctttttgaaaagagtctgaacaagctcgtggaaaac
tacgaagtattgcgcacggcttttgtataccaaaacatgcagcgacctcgccaagtcgtg
ttcaaggaaagaaaagtgaccgttccttgcgaaaacatcgcgcatttgccaagcgcagag
caggacgcgtacatacaagcgtacacgaagcaacatcatacattcgacctgacaaaagac
aacttgatgaaagcagccatttttcaaacggccgagaacaagtaccgattggtttgggcc
ttccatcatattatcgtggacggttggacattgggcgtcttgctgcataagctgctgacc
tattacgcagcgctgcgaaaaggcgagccgattccgcgggaagcgacgaagccgtacagc
gaatatatcaagtggctggataagcaaaacaaggacgaggccctcgcttattggcaaaac
tacctggcagggtatgaccatcaggctgcttttccgaaaaagaagcttggaacggaagca
agccgctatgaacatgtcgaggcgatgttcacgatcgctcccgagaagacgcagcagctg
atccagatcgcgaaccaaaatcaggcgacgatgagcagcgtgtttcaagctctttggggc
attttggccagcacatacaaaaatgcggacgatgtcgttttcggctcggtcgtatcaggc
cgcccgccgcaaatccaaggaattgagagcatggtcggcttgttcatcaacacgattccg
acccgcgtccagacgaacaaacaacagacgttcagcgagctgctgcaaaccgtgcaaaag
caagccctggcgtctgccacctacgatttcgcgccgctgtacgaaattcagagcacaacg
gtgctgaaacaggaattgatcgatcatttggtcacgtttgaaaattaccccgatcattcg
atgaagcatctggaagaatcattagggtttcaatttaccgtagaaagcggagatgagcag
acctcctatgatttgaacgtggtcgtcgccctcgctccctcgaacgagctgtacgtgaag
ctaagctacaatgccgcggtgtatgattcgtcattcgtaaacagaatcgaagggcatctc
cgcaccgtcatcgaccaggtgatcggcaatccgcatgtacacctgcacgagatcggcatc
atcaccgaagaggaaaagcagcaactgctcgtcgcctacaacgacacggctgctgaatat
ccgcgggacaaaacgattttcgagctgatcgcggaacaagcgagccggacaccagcgaaa
gcagcagctgtttgcggcgaggacaccctgacctatcaggagctgatggagcgttctgcc
cagcttgccaatgctttgcgcgaaaaaggaatcgccagcggcagcatcgtctcgattatg
gcggaacattcactggagctgatcgtggcgatcatggctgtcttgcggtcaggtgctgcc
tacttgccgattgatcccgagtacccgcaagatcgcatccagtatttgctcgatgacagc
cagaccacgctgctgttaacccagtcgcatctgcagccaaacatccagtttgcaggcagc
gtgctttatttggacgatcgttccttgtacgaaggcggcagcacatccttcgcacccgag
agcaagcctgatgatttggcgtacatgatctacacttccggttctaccggcaatccaaaa
ggggcgatgattactcatcaaggcctggtcaattacatctggtgggccaacaaggtgtac
gtccaaggcgaagcggtggactttccgctgtactcttccatttcgttcgatttgaccgtc
acctcgatcttcacgccgcttctgtccggcaacacgattcatgtgtacagaggggcagac
aaggtacaggtcattttggacatcatcaaagataacaaagtcgggatcatcaagctgacg
ccgacacacctgaagctgattgaacacatcgacggcaaggccagcagcatcaggcggttc
atcgtcggcggcgagaacttgccgacaaagctggcgaagcaaatttacgaccatttcgga
gagaacgtgcaaattttcaacgagtacggaccgaccgaaaccgttgtcggttgcatgatt
tacttgtatgacccgcaaacaacgacccaggagtcggtgccaatcggtgtcccggcagac
aacgtccagctttatttgctcgatgcttccatgcagccggtgcccgtcggctcgcttggc
gaaatgtacatagccggagacggcgtagccaaagggtatttcaacagaccggagctgacg
aaggaaaagtttatcgacaacccgttccgtccgggaaccaaaatgtatcgaacaggcgac
ctggcaaaatggctgcctgatggaaacatggagtatgcaggcagaatggactatcaagtg
aagattcgcggccatcggatcgagatgggcgaaatcgaaacgcgcctgacgcagcatgag
gcggtcaaggaagcggtcgtgatcgtggaaaaggatgagagcggccaaaacgtgctgtac
gcgtaccttgtttccgagcgggaactgacggtagctgagctgagagaatttttggggcgt
acgctgccttcctatatgattccttccttctttattcgcttggcggaaattccgctgacc
gcgaacggaaaagtagagcgaaaaaaattgccgaagccagctggcgcagtcgttacaggc
accgcgtatgcagctccgcaaaatgaaatcgaggcaaagctggccgagatatggcagcag
gtgctgggcataagccaggtagggattcacgacgatttctttgacttgggcggacactcg
ttgaaggcgatgactgtcgttttccaagtctcgaaagcgctggaagtggaattgcccgta
aaggccttgttcgaacatccaaccgtagcggagctggcccgcttcctttcgcggtcggaa
aaaaccgagtacaccgcgattcaacccgtggcagcgcaggagttttacccggtttcatct
gcgcaaaaaagaatgtatatcctgcaacagttcgaaggcaacggaatcagctacaacatt
tcgggtgcgattctcctcgaaggaaagctggactacgcccggtttgccagcgctgtgcaa
cagctggcagagcgccacgaagctttgcgcacctcgttccaccggatcgacggcgagcct
gtgcaaaaagtgcacgaggaagtagaagtgccgcttttcatgctggaggctcccgaagac
caggcggagaaaatcatgcgcgagtttgtccgtccgtttgatctcggggtcgctccgctg
atgcgaacaggtttgctcaagctgggcaaagaccgccatttgtttttgctcgacatgcac
catatcatctcggacggcgtttcttcgcaaattttgctgcgtgaatttgccgagttgtac
cagggagcagacttgcagccgctttcgctgcaatacaaagattttgctgcttggcaaaat
gagctgtttcagacggaggcatacaagaagcaggagcagcactggctgaacacgtttgct
gatgaaattccgctcttgaacctgccgactgactatccgcgccctagcgtgcaaagtttt
gcaggcgatctcgtcctttttgccgccggaaaagaactgctggagcggttgcaacaggta
ggggcagagactggcaccaccttgtacatgattttgcttgccgcctacaatgtgctgttg
tccaagtataccggccaggaagacatcatcgtcggcacgcctgtcgctggacgttcccat
gcggacgtggaaaacatcatgggcatattcgtgaacacattggcgctgcgcaaccagcct
gccagcagcaaaacgtttgcgcaatttttgcaggaagtgaagcaaaacgcgcttgcagcc
tatgaccatcaagattatccatttgaagaactcgtggaaaaactggcggttcagcgggat
attagccgaaatccgttgtttgacacgttgttttctttggaaaacgcgaaccagcagtcg
cttgccatcgccgagctgacagcgtcgccctatgagctgttcaacaaaatttccaagttc
gatctcgctttgaacgcaagcgaatcgccagcggacattcagttccagctcacattcgca
accaagctgttcaagaaagaaacggtcgagcgaatggcccggcattacctggaaattttg
cgctggatcagtgagcagccaacggcaagcctcgcggacatcgacatgatgacggaagcg
gaaaaacgcacactccttctgaacgtgaacgatacgtttgtcgagcgtaccgccgcgacc
gccttgcatcaattagtggaggagcaagcagcacgcacgcctgatgaagtggccgtcgtg
tacgaagaatatgccttgacctatcgcgagctgaacgccagggcgaaccagctggcccgt
ttgttgcgcagtcacggaaccggaccagatacgttgatcggcattatggtggaccgttcg
ccaggcatggtcgtcgggatgctggctgtgctcaaagcaggcggcgcgtacacgccaatc
gacccaagctatccgccagaacgaatccagtacatgctcagcgacagccaggcgccgatt
ttgctgacgcagcgtcatttgcaggagctggctgcttatcaaggggagatcatcgacgta
gacgaggaagcgatttacaccggagccgacacgaacctggacaacgtcgctggcaaggac
gacttggcctatgtgatctacacatcgggatcgacgggcaatccgaaaggcgtcatgatc
tcccatcaggcgatttgcaatcacatgttgtggatgagagagacgttcccgctgacgacc
gaggatgctgtcctgcaaaaaacgccgttcagcttcgacgcttccgtatgggagttttat
ttgccgctcatcaccggaggacaactggtgttggcaaagccggacgggcatcgcgacatc
gcctacatgactcgtctcattcgagatgagaaaatcacgaccttgcagatggttccgtcc
ttgctggatctggtcatgaccgacccgggctggagcgcatgcacgagcttgcagcgagtg
ttctgcggcggggaagcattgacgcctgccctcgtctcgcgtttttacgagacacagcaa
gctcagttgatcaacttgtacggccctacagagacaaccatcgatgcgacttattggcct
tgcccgcgccagcaggaatacagcgcaattccgatcggcaaaccgatcgacaacgtccgg
ctgtatgtcgtcaatgccagcaaccagctccagccagtaggcgtagcgggagagctgtgc
attgccggagacggtttggcccgcggctattggcagcgcgaggagctgacgaaagcaagc
tttgtcgacaacccgtttgagccgggcggcaccatgtaccgtaccggagacatggtccgt
tatttgccagatggccatatcgagtatttgggacgcatcgaccatcaagtcaaaatcaga
ggtcaccgcatcgagctgggggaaatcgaagccacgcttttgcagcatgaagcggtcaaa
gcggtcgtcgtcatggcccgccaggatggcaaagggcaaaacagcctgtacgcctatgtc
gtagcggaacaggacatccagacagcggagctgagaacgtacctgtctgccaccttgcca
gcctacatggttccgtccgcttttgttttcttggagcagctgccgctttcagcgaacggc
aaagtggatcgcaaggcattgcctcaaccggaggatgccgccgcctctgctgccgtttat
gtggcgccgcgcaacgaatgggaagccaagctcgcagcgatatgggaaagtgtgcttggg
gtcgagccgatcggggttcacgatcatttctttgaactgggcggacattctttgaaagcg
atgcacgtcatttctttgctccagcgcagcttccaggtggacgtaccgttgaaagtcctg
tttgaatcgccaacgatcgcgggcctggccccacttgttgcggctgcccgcaaaggcacg
tacacagcgatcccccctgtcgaaaagcaggagtattacccggtttccgcggcacagaag
cgaatgttcattctgcagcaaatggaaggagcaggtatcagctacaacatgccaggcttc
atgtatctcgacggcaagctggatacagagcggctgcaacaggcgctgaaaagtttggtg
caacgccacgaatcgttgcgcacctcgttccactccgtgcaaggcgagacggttcagcgt
gtgcatgacgatgtcgaactggctatctcgtttggcgaagcgaccgaagcagagacccgg
caaatagccgagcggtttatccagccgttcgatctgggaacagccccgctgttgcgtgcc
ggactcatcaagctggcgccggaacgtcacctgttcatgctcgatttgcaccatattgtc
gtcgatggcgtctccatcggcctgctcatcgaggaatttgcccagctctatcacggggaa
gagctgccagcgctgcgcattcagtacaaagattttgccaagtggcagcaggactggttc
cagaccgaagaatttgccgcgcaggaagcctactggctcaacacctttacgggagaaatc
cccgtgctcaatctgccgacggattaccccagaccgtctgtgaaaagctttgcgggagat
cgcttcgtctttggctccggcactgctttgccaaaacaattgcatcagctcgcccaagag
acaggcacgacactctacatggttctgttggccgcctacaacgtgctcctgtccaaatac
tccagacaagaggacatcatcgtcggcgctcctaccgctggcaggtcccatgccgaaacg
gagtccatcgtcggaatgtttgtcaacacactggccttgcgcaacgagccagccgggggc
aaaactttccgcgactttttggccgaagtgaaaatcaatacgttgggagcgtttgagcat
caagattatccgctcgatgaactcgtcgacaagctggacatgcaacgggatttgagccgc
aaccctttgtttgacacggttttcattttgcaaaatatggagcaaaagccgttcgaaatg
gagcagttgacgattactccttatgtggcagaggtgaagcaagccaaatttgacctgtcg
ctggaggcgtacgaagaaaacgcggaaatcatctttagcctggattacagcaccaagctg
ttttcgcgcgagacgatcgaaaaaatagcgacccattttatccaaatcttgcgggcggtc
atcgcggaaccggaaatgccgttgtccgagatcaccatgctcacagaggcggaaaagcag
cgcttgctggtcgacttcaacggtgcgcacaaagattttccgcaaaacaaaacgcttcag
gcgctttttgaagaacaagcggaaaagtcgccgcaggcaacagccgtggaaatcagcggg
cagcccctgtcctatcaggagctgaatgagcgagccaaccagcttgccgctacgttgcgg
gagcggggagtacagcctgaccaacctgtagggattatggcgaaccgctctgtggagatg
gtcgtcggcatcctcgccatcttgaaagcaggcggagcttacgtgccgatcgacccggaa
tatccggaggagcgtgtcgcctacatgctgacggattgccaagcccgcctggtgctgacg
caaaaacatctgggagcgaagcttggttccagcgtgaccgcagaatgcctgtatctcgac
gacgagagcaactatggtgtgcaccgctcgaatttgcagccgatcaatacggcttccgat
ctggcttacatcatctacacatcgggtacgactggcaagccaaaaggggtcatggtcgag
caccggggcatcgtcaacaacgtgctgtggaagaaagcggagtaccaactgaaggttggc
gacagaagcttgctgtctctgtcctttgcctttgacgctttcgttctgtccttctttacg
cctgtgctttccggggcaactgtcgtactggcggaggatgaagaagccaaggacccagtc
tctttgaaaaagctcatcgccgcttcgcgctgcaccttgatgacaggcgtgccgagcttg
ttccaggccattctggaatgcagcacgccagcggatatccgtccgctgcaaaccgtcaca
ctcggcggagaaaaaattacggcgcagcttgttgaaaaatgcaagcagctgaatcccgat
ctggtcatcgtcaacgagtacggcccgacagaaagcagtgtcgtcgccacttggcagcgc
cttgcgggtccggatgctgccatcaccatcgggcggccgattgccaacaccagcctgtac
atcgtgaaccaatatcaccagctacagccaatcggcgtggtcggggagatttgcatcggc
ggccgcggcttggcacgaggctattggaacaagccagcgctcacggaagagaagtttgtt
tcccatccgtttgcggcaggcgagcgcatgtacaagacgggcgatcttggcaagtggctc
ccggacggaacgattgaatacattgggcgcatcgacgaacaggtcaaagtccgaggctac
cgaattgaaatcggcgagatcgagtcggctctgctggcagcggaaaagctgacagcggct
gttgtggtcgtctatgaggatcagcttggccagtcggctctggcagcgtattttacggcc
gacgaacagcttgatgtcacgaagctgtggtcgcatctgtcgaagcgactcccgtcgtac
atgattcctgcgcattttgtgcagctcgatcagcttccgcttacgccaaacggcaaagtc
gacaagaaagccttgccgaagccagaaggcaagcccgtaaccgaagcgcaatatgtcgcg
ccgacaaatgcggtggaaagcaagctggcagagatttgggaacgcgtgctcggggttagc
ggcatcggcattctcgacaactttttccagatcggcggacattccttgaaagcgatggct
gtcgctgcacaggtgcaccgcgagtatcaggttgagcttccgctgaaagtgctgttcgcg
cagcctacgatcaaggcgttggcccagtatgtcgccacgagcggaaaagagacgtatgtg
ccgatcgagcctgcaccgttgcaagagtattatcctgtttcttccgcgcaaaagcggatg
tatgtcctgcgccagtttgcggacacaggcacggtttataacatgccgagcgcgttgtat
atcgaaggcgatctggagcggaagcgttttgaagccgccatccacggattggtcgagcgg
cacgaatcgctgcgcacatccttccatacggtaaatggcgagcctgtccagcgcgtacac
gagcatgtcgagctgaatgtgcagtacgcggaagtgacggaagcgcaagtggagccaacc
gtcgagtcgttcgtgcaagcatttgatctgacaaaagctccgctattgcgggtcggactt
ttcaagctggcagcgaaacggcatctgttcctgctggatatgcatcacatcatctcggat
ggcgtctcggccggaatcattatggaagagttctcgaagctgtatcgaggcgaagaactg
cctgcgctttccgtccattacaaagatttcgccgtctggcagtctgaactgttccagagc
gacgtctataccgagcatgaaaactactggctgaacgcgttttctggcgacattccggtg
cttaacttgccagccgatttttctcgtccgctgacacagagctttgaaggagattgcgtt
tcgttccaggcagacaaagcgttgctggacgatcttcacaagctcgctcaggagagccaa
tcgacgttgttcatggtattgctggcggcttacaatgtgctgcttgccaagtacagcgga
caggaagacatcgtcgtcggcacaccgattgcgggcagatcgcacgccgatatcgagaac
gttctggggatgtttgtcaacacgctcgctttgcgcaactatccggtcgagacgaaacac
ttccaggcatttttggaagaggtcaagcaaaatacgctgcaagcatacgcccatcaagat
tatccgttcgaagcactggtcgaaaagctggacatccagcgggatctcagccgcaatccg
ctgtttgacaccatgtttattttgcaaaacctggaccaaaaagcttacgagctggatggg
ctgaaactggaggcatatccggcacaagcaggcaacgccaaattcgatctcacgctggaa
gcgcacgaggacgagacaggcattcattttgcgctcgtctactcgaccaaattgttccag
cgagaatcgatcgaaagaatggcgggtcacttcctgcaagtgctgcgccaagtcgttgcc
gaccaagcaactgccttgcgcgagatcagcctgctcagcgaggaagagcgccggattgtg
actgttgatttcaacaacacgtttgccgcgtatccgcgcgatctgacgattcaggagctg
ttcgagcagcaggcagcaagaactccggagcatgcagcggtcgtgatggacggacagatg
ctgacgtatcgggagctgaacgaaaaagcgaaccagctcgcccatgtccttcgtcaaaac
ggagtcgggaaagagagcatcgtcggtctgctcgcagatcgttcgctggaaatgattaca
ggcatcatggggattctcaaagcgggcggcgcctacctgggcctggacccggagcatccg
tccgaacgcctggcttacatgctggaagatggcggcgtgaaagttgtcctcgtgcaaaag
cacttgctgccgctcgtcggcgaagggctgacgccaatcgttttggaagaggagagcctg
caccgggaagattgcggcaatccggcgattgtcaacggtgcgagtgacctggcttatgtg
atgtacacctcaggctctacaggcaagccaaaaggagtcatggtcgagcatcgcaacgtc
acccgcttggttacgcatacgaattacgtgcaagtgcgcgagagcgaccggatgattcaa
accggcgcgattggcttcgacgccatgacatttgagattttcggcgcgttgctgcacggg
gccagcctgtatttggtgagcaaggacgtcttgctggatgccgaaaagctgggcagcttc
ctgcggacgaatcagattacgaccatgtggctgacctcgccgctcttcaaccagctttcg
caagacaatccggcgatgtttgacagcttgcgcgccttgatcgtcggtggcgaagcgttg
tcgccgaagcacatcaaccgagtaaaaagtgcccttcctgacctggaaatctggaacgga
tacggcccgaccgaaaacacgaccttctcgacgtgctatttgattgagcagcattttgaa
gagcagattccgattggcaagccgattgcaaactccaccgcgtatatcgtcgacggcaac
aatcagccgcagccgatcggcgtgccgggtgaactgtgcgtcggtggtgacggtgtcgca
agaggctatgtgaacaagccggaattaaccgccgaaaagtttgtgcccaatccgtttgcg
cctggcgaaacgatgtatcgcaccggagatttggcgagatggctgccggatgggacgatt
gagtatttgggccgaatcgaccagcaggtcaaaatcaggggataccggatcgagcttggg
gaaatcgagacggtcttgtcccagcaggcacaagtaaaagaagcagtcgtggccgtgatc
gaggaggcgaacgggcaaaaagctctctgcgcttactttgtgccagaacaggccgtcgac
gccgccgagctgcgagaagcgatgtccaaacagttgcctggctacatggtccctgcctac
tatgtgcaaatggaaaagctgccgttgaccgcgaacggaaaggtcgaccgccgggcattg
ccgcagccatccggcgagcggacgacaggaagcgcctttgtcgctgcgcaaaatgatacc
gaagcgaagctgcaacagatttggcaagaagttttgggcattccggcaatcggcattcac
gacaacttctttgaaatcggcggtcattccttgaaggcgatgaacgtcatcacgcaagtc
cataagacattccaggtggagctgccgttaaaagcactgtttgccactccgacgatccat
gagttggctgcgcatattgccgagagcgcattcgagcagttcgagacgatccagccagtc
gagcctgccgcgttttatcccgtgtcgtttgcccaaaagcgaatgtacatcctgcatcag
ttcgaaggaagcgggatcagctacaacgtgccgagtgtgctggtgctggaaggcaagctc
gattatgaccgctttgctgctgccatccagagcctggttagacggcatgaatctttgcgc
acctcgttccattcggtaaacggggaaccgctgcaacgagtacatccggatgtcgagctg
cctgtccgccttttggaggcgacagaagatcagagcgaatcgctcatccaggagctaatc
cagccgtttgatctggagatagccccgttgttcagagtgaacctgatcaagcttggcgca
gagcggcacttgttcttcatggatatgcaccacattatttccgatggcgtatcgcttgcg
gtcatcgtcgaggaaattgccagcttgtatgcaggaaaacagctttccgacctgcgcatc
cagtacaaagactttgctgtgtggcagaccaagctggctcagtcggatcgcttccaaaaa
caggaggatttttggacccggacgtttgccggggagattcctttgctgaatctgccccat
gattatccaagaccttctgtgcagagctttgacggtgacacggtcgcgcttggcaccgga
catcacctgctggaacaactgcgcaagctcgctgccgagactggcacgaccttgttcatg
gtgctgctggctgcctaccatgtgttgctctccaagtacgccggacaggaagaaatcgtc
gtcggtacaccgatcgcaggccgctcgcacgcagatgtagagcgcattgtcgggatgttc
gtcaacacgctcgctttgaaaaatacggccgctggcagcctgagcttccgcgcctttttg
gaagacgtgaagcaaaatgcgctccatgccttcgagcatcaagactatccgtttgagcat
ctggtcgagaagctgcaagtgcggcgcgatctgagcagaaacccgctgtttgatacgatg
ttcagcctggggcttgccgaatcagccgaaggagaagtagcggatctgaaagtgtcgcct
tatccggtgaacggccacatcgccaaattcgacctttccctggatgcgatggaaaaacag
gatggacttcttgttcaattcagctattgcacgaagttgtttgcaaaagaaacggttgat
cgactggccgcccattacgttcagcttttgcaaacaatcacagccgatcccgacatcgag
ctcgcccggatcagcgtgttgtccaaagcagagacggagcacatgctgcacagcttcctc
gcaaccaaaacggcctatccgacggacaaaacgttccagaagctgttcgaggagcaagtg
gaaaaaacaccgaacgagattgccgttctgttcggcaatgaacagctgacctatcaggag
ttgaatgcaaaagcaaaccagctcgcccgcgtcctgcggcgaaaaggcgtcaagccggag
agcaccgtcggcattctcgtagaccgctcgctctacatggttatcggcatgctggccgtg
ttgaaagcaggcggaacattcgtcccgattgatccggactacccgctggagcgccaagcg
ttcatgctcgaagacagcgaggcgaagctgctgctcaccttgcaaaaaatgaacagtcaa
gttgccttcccttatgaaaccttttatctggatacagagacagtggatcaggaggagacg
ggcaatctggagcacgttgcgcagccggagaacgccgcttacatcatctacacatccggt
acgacgggcaagccaaaaggggtcgtcatcgagcaccgcagctatgccaatgtcgcgttt
gcctggaaagacgaatatcacctggacagcttcccggtccgtttgctgcaaatggcgagc
ttcgcctttgacgtctcgacgggcgattttgccagggcgctgctgacaggcgggcaactg
gtcatctgcccgaatgaagtcaaaatggacccagcttcgctgtacgagatcatcaggcgt
cacgaaattaccattttcgaagcgacacccgccttgatcatgccgttgatgcactacgtt
tacgaaaacgaactggatatgagccaaatgaagctgctgattctcggagcagacagctgc
ccggcggaagacttcaaaacgttgctcgcgcgcttcggccagaagatgcgcattatcaac
agctacggcgtgacagaggcgtgcattgacaccagctactacgaagaaacagacgtcacc
gccatccgctcgggaacggtgccgatcggcaaaccgcttccgaacatgacgatgtacgtg
gtcgatgcgcatttgaatttgcagcctgtcggcgtcgtaggcgaattgtgcatcggcgga
gcaggggttgcgcgcggttatttgaacagacctgagctgacggaagagaagttcgtgccg
aatccgttcgccccaggtgaacgattgtaccgcacaggtgatctggcgaagtggcgcgca
gatggcaatgtcgagttcctcggacgcaatgaccaccaggtaaaaatcaggggtgttcgc
atcgagctgggcgagatcgagacacagctgcgcaagctggacggaattacggaagcagtc
gtggtcgcaagagaagatcacgggcaggaaaaggaattgtgcgcatacgtcgtggcggac
cacaagcttgacaccgcagaattgcgggcgaatttgctgaaggaactgccgcaagcgatg
attccagcgtatttcgtcaccttggatgcgctgccgctgactgccaatggcaaagtagac
agacgttccttgccagcgccggatgtcaccatgctgagaacgaccgagtatgtagcgccg
cgctccgtctgggaagcccgattggcccaagtatgggagcaggtgctgaatgttccgcaa
gtgggtgcgctggacgactttttcgcgctcggcggtcactccttgcgtgccatgcgtgtc
atttccagcatgcacaacgaataccaggtcgacatcccgctgcgcatcttgttcgaaaaa
ccgacgattcaggaactggcggcgttcatcgaagagacagccaaagggaatgtcttctcg
atcgagcctgtgcaaaagcaagcgtactatccggtttcctcggcacaaaagcgcatgtac
atcctcgatcaatttgagggagtcggcatcagctacaacatgccgtcgaccatgctgatc
gaaggcaagctggagcgaacacgggtggaagcggcgttccagcgcttgattgcgcgacat
gaaagcctgcgcacttcgtttgccgtcgtcaacggagagcctgtgcaaaacattcacgag
gacgttccgtttgcgcttgcctattcggaagtcacagaacaggaggcgcgcgaactcgtt
tcttccctcgtgcagccgttcgatctggaggtcgcaccgctcctgcgcgtctcgctgctg
aaaatcggcgaggatcgttacgtgctctttaccgacatgcatcacagcatttccgatggc
gtatcctccggcattcttctggcagagtgggtgcagctgtatcaaggcgacgttttgccg
gagctgcgtatccagtacaaggactttgctgtgtggcaacaagagttttcccagtcgacc
gccttccacaagcaggaagcgtactggctgcaaacgtttgccgatgacattcctgtgctg
aacttgccgaacgatttcacccgccccagcacccaaagctttgccggggatcagtacacg
atcggcgcgggcaaagcgctcacggaaggcttgcaccagttggcgcaggcgacgggaacg
actttgtacatggttttgctcgccgcgtacaacgtgctgctcgccaagtatgccgggcag
gaggacatcatcgtcggcacgccgattacaggcagatcccatgccgatctcgaaccgatc
gtcggcatgttcgtgaacacgttggcgatgcgtaacaaaccgcagcgcgaaaagactttt
agcgagtttttgcaagaagtcaagcaaaatgcgctggatgcgtacggccatcaggactac
ccgtttgaagagctggtggaaaagctcgcgatcgcgcgcgatttgagccgaaatccgctg
tttgacaccgtgtttacgttccaaaacagcacggaagaggtcatgacgctgcctgaatgc
acgcttgcgccgtttatgacggacgaaacaggccagcacgccaagttcgacttgactttc
agcgctacggaagagcgggaagaaatgacgattggcgtggagtacagcacaagcttgttt
acgcgggaaacgatggaacggttcagccgccacttcctgacgattgcagcgagcatcgtg
caaaatccgcacatccgtctgggcgagatcgacatgcttttgccagaagaaaaacagcag
attttggccgggttcaacgatacggcagtcagctatgcgctggacaaaacgctgcaccag
ctattcgaagagcaggtcgacaaaacaccggatcaggcagcgcttctctttagcgagcaa
tcgctgacgtacagcgaactgaacgagcgagcaaacagactggcaagggtcctgcgcgca
aaaggagtcggaccggaccgtctggtagcgatcatggcggagcgctcgccggaaatggtg
atcggtattctcggtattttgaaggcaggcggcgcttatgttcccgtcgatcccggctat
ccgcaggagcgcattcagtacctgctcgaagatagcaacgcagccctgctgctcagccag
gcgcatctgttgccgctgttggcccaggtgtcaagcgagctgccggagtgccttgatctg
aacgctgaactggatgccggactgagcggctccaacctgccagctgtcaaccaaccgact
gaccttgcctacgtcatctatacatccggtacgaccggcaagccgaagggtgtcatgatc
ccgcatcaaggaatcgtgaactgcttgcagtggagaagagacgaatacgggttcgggccg
agtgacaaggcgttgcaagtgttctcctttgccttcgacggttttgtagccagcttgttc
gctccgctgctcggaggggcaacgtgcgtgttgccgcaagaagcagctgccaaagacccg
gtcgcgctgaaaaaactgatggccgcaacggaagtcacccattactacggcgtaccgagt
ctgttccaggccattctcgattgctcgacgacaaccgacttcaatcagttgcgttgcgtc
actttgggcggcgagaagctgcctgtgcagcttgtgcaaaaaacaaaagaaaagcatccg
gcaatcgagatcaacaacgagtacggcccgacggaaaacagcgtcgtcaccaccatctcg
cgctcgattgaagcggggcaagcgatcacgattggccgaccgcttgcgaacgtccaagtc
tacattgtagatgagcagcatcacttgcagccgattggcgtggtcggtgagctgtgcatc
ggcggagccgggcttgccagaggctatctgaacaaaccggagctgaccgcagagaagttt
gtcgcaaatccgttccgaccaggcgagcgcatgtacaaaacaggcgacttggtaaaatgg
cggacggatggcacgatcgagtacatcggccgcgcagacgaacaggtcaaggtgagaggg
tatcgcatcgagatcggcgagatcgagagcgccgtactcgcttaccagggcatcgatcaa
gcggtggtcgttgcgcgagacgatgacgctacggctggttcctatctttgcgcctacttt
gtcgcagcaacagccgtgtccgtatccggcttgagaagccatctggccaaagagctgcct
gcttacatgattccgagctatttcgtcgagctggatcagctgccgctttccgccaatgga
aaagtggatcgcaaagctttgccgaagccgcaacagtccgatgcgaccacgcgcgaatac
gtggccccgaggaatgcgaccgaacagcaactggcagccatctggcaagaagttttggga
gtagagccaatcggcatcaccgaccagttctttgaactcggaggacattccttaaaagct
acgctgttgattgccaaagtgtatgagtacatgcaaatcgagctgccgctgaatctcatc
ttccagtatccgacgatcgaaaaggtggccgatttcatcacgcataagcgctttgagagc
agatacggcacagccattttgttaaatcaggagacggcgcgaaacgtattttgcttcacg
ccgatcggcgcacaaagcgtgtactaccagaagcttgcggcggaaattcaaggcgtctct
ttgtacagctttgatttcatccaggatgacaaccggatggagcagtatatcgcggcgatc
accgcaattgatccaagcggtccgtacacgctcatgggctactcctcgggaggcaatctg
gcttttgaagtggcgaaagaactggaggagcggggctatggcgtcaccgacatcatcttg
ttcgactcgtactggaaagacaaggcgattgagcggactgtcgcggaaacagaaaacgac
attgcccagctattcgccgagattggcgaaaacaccgagatgttcaacatgacgcaagaa
gacttccagctgtacgccgccaatgagtttgtcaagcaaagcttcgttcgcaaaacggtc
agctatgtgatgttccataacaatctggtcaataccggaatgaccactgccgcgatccac
ctcatccaatccgagctggaagcagacgaggaagctccggtggcagccaagtggaacgaa
tcagcctgggcaaacgcaacgcaacgactgctgacgtacagcgggcacggaatccactcg
cgcatgctggcgggcgattacgcgtcgcaaaatgcttcgattttgcaaaacatcctgcaa
gaactgttcatcctgaaataa

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