Burkholderia pseudomallei 668: BURPS668_A2294 Help Entry BURPS668_A2294    CDS       T00481                                  Name (GenBank) syringomycin synthetase Organism bpd  Burkholderia pseudomallei 668 SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AMP-binding Condensation PP-binding Thioesterase AMP-binding_C Abhydrolase_1 Hydrolase_4 LIDHydrolase Motif Other DBs NCBI-ProteinID:  ABN87372 LinkDB All DBs Position II:complement(2220921..2238941) Genome browser AA seq 6006 aa AA seqDB search MHARAFHSVISPYHIRLPLRRIRIIREYVNTTQEYGVMTDMLDSSEISVRDDIDPVPGAA PERVLALTAGQYGIWLDQMLNPDLPCYILGAILRIDGTFDEALLTSVVNEVVNANDSLRA VLVSEGGSVRQRVLSDVELEIAHIDFSGSVHPHDSAWRYMRTAFDTAFALDGLLCDFRIV RESPSRTYWMYRCHHLVADGQSVSMICRMIVDLYNRRASADMARIEPTPSYFDSLDDDRK YAESSRYERDAQFWQDKFSSLPPPLLSSRSSEAAARPASFPDGQVNLTIERTKYDRLGRI AEASGCTIVHVMFGVLALYFSRAFQVDEVVIGMPVHNRSTAQQKRAIGMFASVVPIRIPV DGNERFVSLLNGVSAELRHCYRHQRFPIAELNRRLGLVRTGRRQLFDLTLSFEKFPLDFY IGDVKLGLTSMRHRFEQTPITVNVQDYHEDQDLVMQFNYDVNAFSHAEVDNIGTRIGGLL DALIEHHDDMPVGMLPLLDEAERKQVVYEWNATERDYPIEQCIHQLFEAQVDRKPEAIAL TFDGRRLGYAELNARANRLAHYLQARGVGPDRLVALCAERGIEMVVGLLAILKAGGAYVP LDPSHPPERLRRMLDDTNPVAVLVDDIGADALASFESHVAARSPRVHLSRDIAQWRACSP ANPSTPRERAARRLAYVIYTSGSSGEPKGVMNEHRGVVNRLWWMQQTYALDERDAVLQKT PFSFDVSVWEFFWPLMSGARLVIAKPEGHKDPAYLSELIDRERVTTLHFVPSMLQAFLED EGAARGCGSVKRVMCSGEALPPSLVKRFYRCLPDARLHNLYGPTEAAVDVTAWACDAEEG GASVPIGRPIANTRIYVLDGYGQPVPRGVAGELYIGGVQVARGYLNRPELTRERFVDDPF VAGGRLYKTGDLARWRTDGSLEYLGRNDFQVKIRGFRIELGEIEAQLAKVAGVRETVVLA RDSGSPADEKRLVAYYTGNADVAALREQATRHLPAYMVPLAYVRLDAWPLTPNGKLDRRA LPAPADDAYARAEYEAPQGAKEEALAAIWKDLLPVERISRHDNFFELGGHSLLVIGLSEK LRAAGLHADVRVVYRASTLADLAAHLGTDNQDIRIPPNLIADGDEHITPAQLTLVALSQE SIDALVTKVEGGAANVQDIYPLAPLQEGILFHHLMSGESDPYVLSGVLAFRSREVMERFV SALQQVIDRHDILRTGFFWEGLEQPVQVVQRRATLPVSVVELDAREGDIVRQLETRFDSR GYRMDVSRAPLMHVHAACDGEHERWVARVLFHHLSIDHTTLERVIEEARAIGQGRVEDLP RPVPFRNFVAQARLGVSEADHEAYFRAKLGDIDEPTAPFGLLSVQGDGREIAEAARRLKP ELSGALRGHARRLGVSAASMMHVAWGLVLSRTTGRQDVVFGTVLFGRMQGGAQSDRALGL FINTLPVRMRVAQTSVEASVKETHAQLAELMRHEHAPLVLAQRCSGVPAQTPLFTSLLNY RYSKPKVAAAHIADGIELLDGHERTSYPLSVTVDDHERDFTIVAKVCERIGPQRVCELME LALEQLTRALGANPGGELAELDVLPAAERTQVLHGWNETGRAYARDACLHQLFEAQVSRT PEAAAVICGDETLSYTDLDARANRLAHYLRGQGVGPDTRVGLALGRGVEMMTGLLAILKA GGAYVPLDPGYASERLRAILDDSRPAIVLADAAGRTALDALAGAPPIADLQADASRWSAL PSTPPRVEGLTPRHLAYVIYTSGSTGQPKGVMVEHASVVNLWRALDEAIYRAHPSARRVS LNASIAFDSLVKQWVQLLSGRTLVVVPEPVRFDGRRLLDAIGRDRIDVFDCTPSQLALIE GARGPEDEAYPQVTLVGGEAIGEGMWSELASVSSRTYYNVYGPTECTVDATLARITAEHA PHIGGPLANVRAYVLNERLSPAPVGVRGELYIGGAGVARGYLNRPELTRERFIDDPFVAG GRLYRTGDLARWRTDGRLEYLGRNDFQVKIRGFRIELGEIEAQLAKVADVREVVVLARDS AAEVHDSATEHATPNAPSPSPETSTATAAATATATATEKRLVAYYTGDADVTALRAQAAQ HLPSYMVPSAYVRLDAWPLTPNGKLDRRALPAPADDAYARAEYEAPQGAKEEALAAIWRE LLHVERVSRHDNFFELGGHSLLAVQLVSRLRQALSVEVALGTVFDAPVLSALAERLEAEN TAVLPPIPLAPRDGRIALSLAQQRLWFLTQLEGVSEAYHMSGAVRLDGPLNREVLQRALN RIVMRHEALRTCFAREEGEPIQVIQPHADLTMSYHDLREAESIRHEAGNLEQRAKDLSQA HASAPFDLSRDLPVRVLLLQLEDEAHVVQVVMHHIASDGWSVGVFLQELSALYGSFIAEQ GDPLAPLPLQYADYAAWQRRWLASGQLEKQGAFWQTNLSGAPTLLELPTDRPRPPKQSHA GASVEVKLGAALSERVKRLSQRHGVTPYMTLLSSWAAVLSRLSGQEEVVIGSPVAGRNRT EVEALIGFFVNTLALRLDLSSEPTVGELLKRTKAQVLSAQAHQDLPFDQVVERVKPPRST AHPPLFQVMFVWQNAHEGSLQIPGLRLSTWGDPLTMAPFELTLAVREHQDDIACTLTYAT SLFDRATVERYLGHWLRQLDAMATDADPVVTGLPLLGEAERAQVLHGWNETGRAYARDAC LHQLFEAQVSRTPEAAAVICGDETLSYTDLDARANRLAHYLRGQGVGPDTRVGLALGRGV EMMTGLLAILKAGGAYVPLDPGYASERLRAILGDSRPAIVLADAAGRTALDALAGAPPIA DLQADASRWSALPSTPPRVEGLTPRHLAYVIYTSGSTGQPKGVMVEHASVVNLWRAVDEA IYRAHPSARRVSLNASIAFDSLVKQWVQLLSGRTLVVVPEPVRFDGRRLLDAIGRDRIDV FDCTPSQLALIEGARGPEDEAYPQVTLVGGEAIGEGMWSELASVSSRTYYNVYGPTECTV DATLARITAEHAPHIGGPLANVRAYVLNERLSPAPVGVRGELYIGGAGVARGYLNRPELT RERFIDDPFVAGGRLYKTGDLARWRTDGKLEYLGRNDFQVKIRGFRIELGEIEAQLAKVT GVREVVVLARDSASEVHDSATEHATPNALSPSPETSTATAAATAATTATATATEKRLVAY YTGDADVAALRAQAAQHLPSYMVPSAYVRLDAWPLTPNGKLDRRALPAPADDAYARAEYE APQGAKEEALAEIWRDLLQVDQISRHDNFFQLGGHSLLAISLGDMMRERGLHADVRTLFN AETLAALAAQSGTDSIDVDVPPNLIPVGAARITPDMLPLVALTQPQIDAIAQQVDGGATN VQDIYPLAPLQEGMLFHHLLHTQGDLYLEPHLLAFRTRERLERFLSALQCVIDRHDVLRT GFFWEGVPQPVQVVWRRARLPVEYVELPDSHGDVASQLEARCDPRRHRIDIGRAPLVHCH VAHDARNDRWVLGVLTHHLVSDHTTLALLAEEAQAFEQGRGDALPPAVPFRNFVAHARLG TSEREHEAFFREMLGDVDEPTAPFGLLDVQGDGSAIVEHRRALAPGLSRSVRAHARRLGV SAASVMHVAWSLVLARTANRRDVVFGTVLFGRMQGGAHAHRTMGLFMNTLPVRIALDESD VETSLIATHDRLARLLRHEHAPLALAQRCSAVPAQAPLFTSLLNYRYSPHEEQGDATDDD VQFIAARERNNYPLTMIVDDTGEGFALTAQVDASIDAARVCAFMHTALEQLVRALDDARG AVLAELDVLPADEHRCVVSACNDTDAELPGVDFVDRRFEAQAARTPEAIAVACGAHALSY AALNRRANRLAHYLRAHGAGPERVVALALERSVDMMVGLLGILKSGSAYLPLDPAYPAER LAYIVDDARPALLLTEAALRDDWRDAGAPVVLLDADGPAIDACPDHNPDDAGRDARTLSS LAYVIYTSGSTGRPKGVMIEHRNLANLLGAMGEQPGIGAHDVLLAVTSLSFDIAALELFL PLLHGARAVIAARDDAADPARLAHLIESSGASLMQATPSTWRMLAQHGWPRSARPLTLLC GGEALPPALAERLLAHVPAIWNLYGPTETTVWSTVRRVTTPVVDIGGPIANTQVYVLDER LRPAPIGVAGELYIGGAGVARGYLNRPELTRERFVDDPFRRGGRLYRTGDLARRRADGNL EYLGRNDFQVKIRGFRIELGEIEAQLAKAHGVQGVALAARDTPTADKRLVAYYVGDASAA ALREHAAARLPAYMVPAAYVRLAAWPLTPNGKLDRAALPAPDDEAYARAEYEAPRGEHEC KLAAIWRAVLQVERIGRHDDFFELGGHSLLAVRAVTAMRDAFGSDTSLRDLFARPVLKDL AEHASTAARARDAAIPKVARGEPAPMSFAQQRLWFLARMGGLGDAYHMPIAVRLRGALDV DALQRALSRIVSRHDALRTTFALEGEQPVQRVHADDGAGLRLRIDDLRGCADAGARRARI LAGQASEPFDLARGPLVRGALVREADDVHTLCVTIHHIVSDGWSIDVFCRELSELYRAFA GGRPDPLPPLPVQYADYAAWQQRGIGGAALHAQAEYWRDALAGAPTLLELPTDRPRPPQP DYAGATVGLALDAPLTAGLRALARRHGATLFMTVFAAWSVLLSRLSRQTDVVIGTPSANR GHAQIEGLIGFFVNTIALRVDLDGAPTVAELLARVKARTLAAQQHQDIPFEHVVERVQPA RSLSHSPVFQAMFAWQHASRGEMRLEGLRAEPLDDAARTIAKFDLTLSLRESGDAIDGGL EYASALFERATIERFAGYLRRLLEGMVADDTQRVDALPMLSRDERRDLIERRNATARPYP ANSGVHRLFEAQAARTPDATAIVDGATTLDYRALDARANRIAHALAHAGVRAGDRVALHL EPSIGLVAAQLAVLKLGAAYVPVDVGNPPARKAFVAQDSGARLVLGDAALDWPAAAGVPQ RDLAALLAGPWPSDAPARAPQCGGDTPAYVMYTSGSSGQPKGVLVTHRGIARLAVNSGYA TFDASDRFAFASNPAFDASTFEVWTALLNGASIGIVKRDDLLDLGALAGKLSSIGVTCLF LTTALFNRCVSFDPAMFARLRCVISGGERADPAVYRKVLEAGPPRHLLNAYGPTETTTFA AVWEAEPRTLAAQAAPIGRPIGNTSVYVLDAYGAPVPVGVTGEIHIGGPGVAQGYLNRPA LSAERFVRDPFVGGDARMYRTGDLGRWRPDGMLDCIGRADFQVKIRGFRIELGEIEACLL EHGALAQAAVLARDDGGDGGKTLVAYYVPRAGHEDGAPALRAHLAARLPEYMVPAAYVRL PAMPLTPNGKLERRALPAPDERSYVRRDYAAPQGEIETTLARIWAELFGIERVGRHDGFF ELGGHSLLAVRMVARVHDVLGVEVPLRALFADPVLHVFASAVARASTRQASSNLVAFRSA GTAAPLFFIHSGLGEIGFVGDLLPGIAPEIPVYGFAAVGFLAGETPHATIEEMAAQYVDA MRRVQPHGPYRLAGWCAGGNIAFEMAHQLIAADETVEFLCMIDSPTSAPIDRSVTACVLA RIPDDIPEALRTRLHALGDAFDVRGMLHACQAAGMLPIDLPTGLMERHVAVQYAIKHAKL NYVPPRLPVDVIHFVAQDEPMWRNGWAMDGWHDVADRVICLPASGDHMTMVAAPHAEQLG RRITEALAVHGGPRADGAERGYAPRIAIQTAPRDARAPTLFCIPGAGASVTTFSTLARHL PATFSVDGLQPRGLCGTMVPYLDVETAARAYLRSIRKAAPRGPYHLVGHSFGGWVAYEIA CRLQEQGERVATLMLLDTERPGATDIVRGRKTRVDALAKLVELYEMHLGRPLGVSRDDLA ALAHDAQIEHLRAALVRAKILPPSVHPNVLLGVVRVLEMNVNTPYRPAGLYAGTMHVVLI ANAKADADLDAWRDEQAEQWRGLADDVRIVRAGGNHMTMLQPPHAASIAALLERTAGAPA RLAQVH NT seq 18021 nt NT seq  +upstreamnt  +downstreamnt atgcatgcgcgggcgtttcattcggtgatatcgccgtatcacattcgccttccgttgcgg cgcattcgaatcattcgtgaatacgtgaacacgactcaggagtatggcgtcatgactgac atgctcgattcttcggaaatttcggtccgcgacgatatcgatcccgttccgggcgccgcg cccgaacgcgtccttgcgctgacggccggccagtacggcatctggctcgatcaaatgctc aatccggatctgccgtgttacatcctcggcgcgattcttcgaatcgacggtacgttcgac gaggcgttgctgacgtcggtcgtcaacgaagtcgtcaatgcgaacgattccctgcgcgcg gtgctggtgagcgaaggcggttcggtgcggcagcgtgtcctgtccgacgtggagctggag attgcgcatatcgatttttccggctccgtgcacccgcacgacagcgcgtggcgatacatg cgaacggcgttcgatacggcgttcgcgctcgacggactgctgtgcgatttccgcatcgta cgcgagagcccgtctcgcacgtactggatgtatcgctgccatcatctggttgcggacggt cagagcgtgtcgatgatctgccggatgatcgtcgatctctataaccgccgtgcgagcgcg gacatggcgcgcatcgagccgacgccctcctatttcgattcgctcgacgacgaccgcaag tatgccgagtcgtcccgttacgagcgcgacgcgcagttctggcaggacaaattttcgtcg cttccgccgccgttgctttcgtcgcgctcgagcgaggcggccgcacgccccgcgtcgttt cccgacggccaggtgaatctgacgatcgagcgcacgaagtacgatcggctcgggcggatc gccgaggcgagcggatgtacgatcgtccacgtgatgttcggcgtgctcgcgctctacttc tcgcgagcgtttcaggtcgacgaggtggtgatcggcatgccggtgcacaaccgaagcacc gcacagcagaagcgcgcgatcggcatgttcgcttcggtggtgccgattcgcatcccggtc gacgggaacgagcgtttcgtatcattgctgaacggcgtgtcggccgagttgcggcattgc tatcgccatcagcgttttccgatcgcggagttgaaccggcgtctggggctcgtgcgaacc ggtcgcaggcagcttttcgatctcacgctgtcgttcgagaagttcccgctcgatttctac atcggcgacgtcaagctagggctgacatcgatgcggcaccgtttcgagcagacgccgatc acggtcaacgtccaggattatcacgaggaccaagacctcgtcatgcagttcaattacgac gtcaatgcgttctctcatgcggaggtcgacaacattggcacgcgcatcggcgggttgctc gatgcattgatcgagcatcacgacgatatgccggtgggcatgctgccgttgctcgacgaa gccgaacgcaaacaggtggtgtacgagtggaacgcaacggagcgtgactatccgatcgag cagtgcattcatcagttgttcgaagcgcaggtggatcggaagccggaggcgattgcgctg acgttcgacgggcggcgactgggctacgcggaactcaacgcccgagcgaaccggcttgcg cactatctgcaggcgcgcggcgtgggcccggaccgactggtcgcgctttgcgccgaacgc ggaatcgagatggtggtggggctgctggcgatcctgaaggcgggcggcgcgtatgtgccg ctggatccgagccatccgcccgagcgtttgcgccggatgctggacgatacgaacccggtg gcggtgctcgtcgacgacatcggcgcggacgcgctcgcatcgttcgaatcacatgtcgcg gcccgttcgccacgtgtgcacctgtcgcgcgacatcgcgcaatggcgggcatgcagcccg gcgaatccgtccaccccacgggagcgcgcggcgcggcgtctcgcatacgtgatctacacg tcgggctcgagcggcgagccgaagggcgtgatgaacgagcatcgcggggtggtgaaccgg ctgtggtggatgcagcagacgtacgcgctggacgagcgcgacgcggtattgcaaaagacg ccgttcagcttcgacgtatcggtgtgggagttcttctggccgctgatgtcgggcgcgcgg ctggtgatcgcgaagccggaggggcacaaggatccggcgtacctgtcggagttgatcgat cgcgaacgcgtgacgacgctgcacttcgtaccgtcgatgctgcaggcgttcctggaggat gagggcgcggcccggggctgcgggagcgtgaagcgggtgatgtgcagcggagaggcgctg ccgccgtcgctggtgaagcgcttctatcgttgcttgccggatgcgcgcttgcacaatctg tacggtccgacggaagcggcggtggacgtgacggcgtgggcgtgcgatgcggaagaaggg ggcgcgtcggtgccgatcggtcggccgatcgcgaacacgcggatctacgtattggacggg tatggccagccggtgccgcgaggggtggcgggggaactgtatatcggcggcgtgcaggtg gcgcgagggtatctgaaccggccggagctgacgcgggagcggttcgtcgacgatccgttc gtggcgggcggtcgactctataagacgggagatttggcgcgttggcgcacggacgggagt ctggagtatctgggtcgaaacgatttccaggtgaagatacgcggtttccggatcgagttg ggggagatcgaggcgcaactggcgaaggtggcgggcgtgcgcgagacggtggtgttggcg cgcgactcgggttcgcctgccgacgagaaacgcctcgtcgcgtactacacggggaatgcc gatgttgcggcgttgagggaacaggcaacacgacatctgccggcctacatggtgccattg gcgtacgtgcggctggacgcgtggccgctgacgccgaacggcaagctggaccggcgcgca ctgcccgcgccggcggacgacgcgtacgcccgcgccgaatacgaagcgccgcagggcgca aaggaagaagcactggccgcgatctggaaggacctgctgcccgtggagcgcatcagccgc catgacaatttcttcgaactcggcgggcattcgctgctcgtgatcggcttgagcgagaag cttcgggcggcgggcttgcatgccgacgtgcgtgtcgtctaccgggcgtcgacgctggcc gatctcgccgcgcatctggggaccgacaatcaggacatccggataccgccgaatctgatt gccgacggcgacgagcacattacgccggcccaactgacgctggtggcgctgagccaggag tcgatcgacgcgttggtgacaaaggtggaaggcggcgcggcgaacgtgcaggacatctat ccgttggcgccgttgcaggaaggcattctgtttcatcacctgatgtcgggggaaagtgat ccgtacgtgctgtcgggcgtgctggcgttccgcagccgcgaggtgatggagcggtttgtg tcggcattgcagcaggtgatcgatcggcacgacatcctgcgcaccggcttcttctgggag ggactcgagcaaccggtgcaggtcgtgcagcgccgggcgacgttgccggttagcgtcgtc gagctcgatgcacgcgaaggcgacatcgtgcggcaactggagacccgcttcgattcgcgc ggctatcggatggacgtgagccgcgcgccgttgatgcacgttcacgcggcttgcgacggc gagcacgaacgctgggtggcgcgcgtgctgtttcaccatctgtcgatcgatcatacgacg ctcgagcgtgtgatcgaggaggcgcgcgcgatcgggcagggccgagtggaggacttgccg cggccggtgccgttccggaatttcgtcgcgcaggcgaggctgggggtgagcgaggcggac cacgaggcgtacttcagggcgaagctgggggacatcgatgagccgacggcgccgttcggt ctgctgagcgttcagggagacgggcgtgagatagcggaggcggcgcggaggttgaagccg gagctgtcgggggcgcttcgcggacatgcgcgccggctgggggtgagcgcggcgagcatg atgcatgtggcgtgggggctggtgctgtcgcgcacgacggggcggcaggacgtggtgttc ggcacggtgctgttcgggcggatgcagggaggcgcgcaatcggatcgagcgctgggcttg ttcatcaacacgttgccggtgcggatgagggtagcgcagacgagcgtggaggcgagcgtg aaggagacgcatgcgcaactggcggaattgatgcgtcacgagcatgcgccgctggtgctg gcacagcgttgcagcggggtgccggcgcagacgccgttgttcacgtcgctgctgaactat cggtacagcaagccgaaggtcgcggccgcgcatattgccgacggcatcgaattgctcgac gggcacgagcgaaccagttatccattgagcgtgaccgtggatgatcacgagcgcgatttc acgatcgtcgcgaaggtttgtgaacggattgggccacagcgcgtatgcgaactcatggaa ctggcgttggagcagctgactcgcgcgctgggcgcaaatccgggcggtgaattggctgag cttgacgtattgccggccgccgaacgcacacaggtactgcacggctggaacgaaacaggc cgcgcgtatgcgcgggatgcctgcctccatcagttgttcgaagcgcaggtatcgcgaacg ccggaagcggcggcggtgatctgcggcgacgagacgctgagctatacggacctcgacgcg cgtgcgaatcgcctcgcgcactacctgcgcggacaaggcgtcgggccggacacgcgcgtg gggctggcgctcgggcgcggcgtcgagatgatgacgggattgttggcgatcttgaaggcg ggcggcgcatatgtgccgctggacccgggctatgcatcggagcgcttgcgcgcgatcctg gacgacagccggccggcgatcgtgctggcggacgcggcggggcgcacggcgctggatgcg ctggccggtgcgccgccgattgcggacctgcaagcggatgcgtcgcgctggagcgcgttg ccttcgacgccgccgcgtgtcgaaggcctgacgccgcgccaccttgcctatgtgatctac acgtcgggctcgacgggacagccgaagggggtaatggtcgagcacgcaagcgtggtgaat ctgtggcgtgcgctggacgaggcgatctaccgcgcgcatccgagcgcgcggcgcgtgagc ctgaacgcatcgatcgcgttcgattcgctggtcaagcagtgggtgcagttgctgtcgggg cggacgctggtggtggtgccggagccggtgcgcttcgacgggaggcgtctgctcgatgcg atcgggcgagaccggatcgatgtcttcgattgcacgccgtcgcaactggcgttgatcgag ggggcgcgagggccggaggacgaagcctatccgcaagtgacgctggtggggggcgaggcg atcggcgaagggatgtggtcggagttggcgagcgtatcgagccggacgtactacaacgtg tatggtccgacggaatgcacggtggatgcgacgctcgcgcggatcacggcggagcatgcg ccgcacatcggcgggccgctggcgaacgtgcgggcctatgtgttgaacgagcggttgagc ccggcgccggtgggcgtgcgcggggagctctacatcggcggggcgggcgttgcacgcggg tacttgaaccggccggagctgacgcgggagcggttcatcgacgatccgttcgtggcgggc gggcggctgtataggacgggggatctggcgcgttggcgtacggacgggaggctggaatat ctggggcgaaacgacttccaggtgaagatacgcggtttccggatcgagttgggggagatc gaggcgcaactggcgaaggtggcggatgtgcgcgaggtggtcgtgcttgcgcgagattcg gcagcggaggtgcacgatagcgcgacggaacacgcaactccgaatgcgccttcgccctcg cccgagacctcaaccgcgacagcagcggcaacagcaacggcaacagcgaccgagaaacgc ctcgtcgcgtactacacgggcgacgccgatgtcacggcattgagagcgcaagccgcgcag cacttgccgagctacatggtgccgtcggcgtatgtgcggctggacgcgtggccgctgaca ccgaacggcaagctggaccggcgcgcgctacccgcgccggcggacgacgcgtacgcccgc gccgaatacgaagcgccgcagggcgcaaaagaagaagcactggccgcgatctggcgggag ctgctgcatgtggagcgcgtcagccgccacgacaacttcttcgaactcggcggccactcg ctgctggcggtgcaactggtatcgcgcctgcggcaggcgctgtcggtggaggtggcgctg ggcacggtgttcgacgcgccggtgctgtcggcactggccgagcggctcgaagcggagaac acggcggtcctgccgccgataccgctggcgccacgcgacggaagaatcgcgctgtcgctg gcgcagcaacggctatggttcctgacgcaactggaaggcgtcagcgaggcgtaccacatg agcggcgcggtgcggcttgatgggccgttgaatcgagaggtgctgcaacgtgcgctgaac cgtatcgtgatgcgccacgaagcactgcggacgtgcttcgctcgggaggagggtgaaccg atccaggtgatccagccgcatgccgatctgacgatgagctatcacgacctgcgcgaagcg gagtcgatccgacatgaagccgggaacctcgaacagcgggcaaaggacctgagccaagcc cacgcatcggcgccattcgacctgagccgagacctgccggtgcgagtgctgctgctgcaa ttggaagatgaagcccacgtcgtgcaggtggtgatgcatcacatcgcatcggacggctgg tcggtcggggtgttcctgcaagagctgagcgcgctgtacgggtcgttcatcgcggagcag ggcgatccgctggcgccgctgccgttgcaatacgcggactacgccgcatggcaacgcagg tggctggcgagcggccagttggagaagcaaggcgcgttctggcaaacgaacctgtccggc gcaccgacgctgctggagctgccgacggaccgtccgcgtccgccgaagcaatcgcacgcg ggcgcgagcgtcgaggtgaagctgggcgcggcgttgagcgaacgggtgaagcgcctgagc caacgccacggggtgacgccgtacatgacgctgctgtcgagctgggcggcggtgctgagc cggttgagcggacaggaggaagtggtgatcggcagcccggtcgcggggcggaaccgaacg gaggtcgaagcgctgatcggtttcttcgtgaacacgctggcgttgcggctggatctgtcg tcggagccgacggtgggcgaattgctgaagcggacgaaggcgcaggtgctgtcggcgcag gcgcatcaggacttgccgttcgatcaggtggtggagcgggtgaagccgccgcgcagcacc gcgcatccgccgctgttccaggtgatgttcgtctggcagaacgcgcacgaaggcagcttg cagattcctgggttgcgtctgagcacatggggcgatccgctgacgatggcgcctttcgag ctgacgcttgccgtccgcgagcatcaggacgatatcgcgtgtacgttgacctatgcgacg tcgttgttcgatcgagcgacggtcgagcgctatctcggccactggctccggcagctcgac gcaatggcgaccgatgcggatcccgtcgtcacaggcctgccgctgctcggcgaagccgag cgcgcgcaggtactgcacggctggaacgaaacaggccgcgcgtatgcgcgggatgcctgc ctccatcagttgttcgaagcccaggtatcgcgaacgccggaagcggcggcggtgatctgc ggcgacgagacactgagctatacggacctcgacgcgcgtgcgaatcgcctcgcgcactac ctgcgcggacaaggcgtcgggccggacacgcgcgtggggctggcgctcgggcgcggcgtc gagatgatgacgggattgttggcgatcctgaaggcgggcggcgcatatgtgccgctggac ccgggctatgcgtcggagcgcttgcgcgcgatcctgggcgacagccggccggcgatcgtg ctggcggacgcggcggggcgcacggcgctggatgcgctggccggtgcgccgccgattgcg gacctgcaagcggatgcgtcgcgctggagcgcgttgccttcgacgccgccgcgtgtcgaa ggcctgacgccgcgccaccttgcctatgtgatctacacgtcgggctcgacgggacagccg aagggggtgatggtcgagcacgcaagcgtggtgaatctgtggcgtgcggtggacgaggcg atctaccgcgcgcatccgagcgcacggcgcgtgagcctgaacgcatcgatcgcgttcgat tcgctggtcaagcagtgggtgcagttgctgtcggggcggacgctggtggtggtgccggag ccggtgcgcttcgacgggaggcgtctgctcgatgcgatcgggcgagaccggatcgatgtc ttcgattgcacgccgtcgcaactggcgttgatcgagggggcgcgagggccggaggacgaa gcctatccgcaagtgacgctggtggggggcgaggcgatcggcgaagggatgtggtcggag ttggcgagcgtatcgagccggacgtactacaacgtgtatggtccgacggaatgcacggtg gatgcgacgctcgcgcggatcacggcggagcatgcgccgcacatcggcgggccgctggcg aacgtgcgggcctatgtgttgaacgagcggttgagcccggcgccggtgggcgtgcgcggg gagctctacatcggcggggcgggtgttgcgcgcgggtacttgaaccggccggagctgacg cgggagcggttcatcgacgatccgttcgtggcgggtgggcggctgtataagacgggggat ctggcgcgttggcgcacggacgggaagctggaatatctgggtcgaaacgacttccaggtg aagatacgcggattccggatcgagttgggggagatcgaggcgcaactggcgaaggtgacg ggggtgcgcgaggtggtcgtgcttgcgcgagattcggcatcggaggtgcacgatagcgcg acggaacacgcaactccgaatgcgctttcgccctcccccgagacctcaaccgcgacagca gcggcaacagcagcgacaacagcaacggcaacagcgaccgagaagcgcctcgtcgcgtac tacacgggcgatgccgatgtcgcggcattgagagcgcaagccgcgcagcacttgccgagc tacatggtgccgtcggcgtacgtgcggctggacgcgtggccgctgacgccgaacggcaag ctggaccggcgcgcattgcccgcgccggcggacgacgcatacgcccgcgccgaatacgaa gcgccgcagggcgcaaaagaagaagcactggccgagatctggcgggacctgctgcaagtc gatcaaatcagccgccacgacaacttcttccagttgggcggtcattcgctgctggcgatc agcctgggcgacatgatgcgcgagcgcggcttgcacgccgacgtgcgcacgctgttcaac gcggagacgctggccgcgctcgccgcgcaatcgggcacggacagcatcgacgtcgacgtc ccgccgaacctgatccccgtcggcgccgcgcgaatcacgcccgacatgctgccgctcgtc gcgctgacccagccgcagatcgacgcgatcgcgcagcaggtagacggcggcgcgacgaac gtacaggacatctatccgctcgcgccgctgcaggaaggcatgctgttccatcatctgctg cacacgcagggcgacctctatctggaaccgcatctgctcgcgttccgcacgcgcgagcgg ctcgagcggttcctgtccgcgctgcaatgcgtgatcgaccgtcacgacgtgctgcgcacc ggcttcttctgggaaggcgtcccgcagccggtgcaggtggtgtggcggcgcgcgcggctg ccggtcgaatacgtcgagctgccggacagccacggcgatgtcgcgagccagctcgaagcc cgctgcgatccgcgccgccatcgcatcgacatcggccgcgcgccgctcgtgcactgtcac gtcgcgcacgatgcgcgcaacgaccgctgggtgctcggcgtgctgacgcaccatctggtc agcgaccatacgacactcgcgctcctcgccgaagaagcgcaggcgttcgagcagggccgc ggcgatgcgctgccgcctgcggtgccgtttcgcaacttcgtcgcgcacgcgcgcctcggc acgagcgagcgcgagcacgaagcgttcttccgcgagatgctgggcgacgtcgacgagccg accgcgccgttcggcctgctcgacgtgcagggcgacggcagcgcgatcgtcgagcaccgg cgcgcgctcgcgcccgggttgtcccgctcggtgcgcgcgcacgcgcggcgtctcggcgtg agcgcggcgagcgtgatgcacgtcgcatggagcctcgtgctcgcgcggacggcgaaccgg cgcgacgtggtgttcggcacggtgctgttcggccgcatgcaaggcggcgcgcacgcgcat agaacgatgggcctcttcatgaacacgctgcccgtgcggatcgcgctcgacgagtcggat gtcgagacgagcctgatcgcgacgcacgatcgcctcgcgcggctgctgcgccacgagcac gcgcccctcgcgctcgcgcagcgctgcagcgcggtacccgcgcaggcgccgctgttcacg tcgctgctgaactaccgctattcgccgcacgaagagcagggcgacgcaacggacgacgac gttcagttcatcgccgcgcgcgagcgcaacaactacccgctgacgatgatcgtcgacgac acgggcgagggcttcgcgctcacggcgcaggtggacgcctcgatcgacgcggcgcgcgtc tgcgcgttcatgcatacggcgctcgagcagctcgtgcgcgcgctcgacgacgcgcgcggc gcggtgctcgccgagctcgacgtgctgcccgccgacgagcatcggtgcgtggtgtcggcc tgcaacgatacggatgccgaactgccgggcgtcgacttcgtcgatcgccggttcgaggcg caggcggcgcgcacgcccgaggcgatcgccgtcgcgtgcggcgcgcacgcgctcagctac gcggcgctgaaccggcgtgcgaatcgcctcgcgcactatctgcgcgcgcacggcgcgggc ccggagcgcgtcgtcgcgctcgcgctcgagcgctcggtcgacatgatggtcgggctgctc ggcatcctgaaatcgggcagcgcctatctgccgctcgatcccgcgtatccggccgagcgg ctcgcgtacatcgtcgacgacgcgcgccccgcgctgctgttgactgaagccgcgctgcgg gacgactggcgagacgccggcgcacccgtcgtgctgctcgacgcggacgggccggcgatc gacgcgtgtccggatcacaacccggacgatgccggccgggatgcgcgcacactgtcgtcg ctcgcgtacgtgatctacacatcgggttcgacggggcgcccgaagggcgtgatgatcgag catcgaaatctcgcgaacttgctcggcgcgatgggcgagcagcccggcatcggcgcgcac gacgtgctgctcgcggtgacctcgctgtcgttcgacatcgccgcgctggagctcttcctg ccgctgctgcacggcgcgcgcgcggtgatcgcggcgcgcgacgacgcggccgatccggcg cggctcgcgcatctgatcgaaagcagcggggcgagcctgatgcaggcgacgccttcgacg tggcgcatgctggcgcagcacggctggccgcgatcggcgcggccgctgacgctgctgtgc ggcggcgaggcgctgccgcccgcgctcgccgagcggctgctcgcgcatgtccccgcgatc tggaacctgtacgggccgacggagaccacggtatggtcgaccgtgcggcgcgtgacgacg cccgtcgtcgacatcggagggccgatcgccaacacgcaggtctacgtgctcgacgagcgg ctgcgccccgcgccgatcggcgtcgcgggcgagctgtacatcggcggcgcgggcgtcgcg cgcggctatctgaaccgccccgagctcacgcgcgagcgcttcgtcgacgatccgttccgg cgcggcgggcggctgtaccgcaccggcgatctggcgcggcggcgcgcggacggcaacctc gagtacctcggccgtaacgatttccaggtgaagattcgcggcttccggatcgagctcggc gaaatcgaggcgcagctcgcgaaggcgcacggcgtgcaaggcgtggcgcttgccgcgcgc gacacgcccacggcagacaagcggctcgtcgcgtactacgtcggcgacgcgagcgccgcg gcgctgcgcgagcacgcggccgcgcgattgccggcgtacatggtgccggcggcctatgtg cggctcgccgcgtggccgctgacgccgaacggcaagctcgaccgcgcggcgctgcccgcg ccggacgacgaagcgtacgcgcgcgccgaatacgaagcgccgcggggcgagcacgagtgc aagctcgcggcgatctggcgggccgtgctgcaggtcgaacggatcggccgtcacgacgat ttcttcgagctgggcggccattcgctgctcgcggtgcgcgcggtcacggcgatgcgcgat gcgttcggcagcgacacgagcctgcgcgacctgttcgcgcggcccgtgctgaaagatctc gccgaacacgcgagcacggccgcgcgtgcgcgcgacgcggcgatcccgaaggtcgcgcgc ggcgagcccgcgccgatgtcgttcgcgcagcagcggctgtggttcctcgcgcggatgggc gggctcggcgatgcgtatcacatgccgatcgccgtgaggctgcgcggcgcgctcgacgtc gacgcgctgcagcgcgcgctgagccgaatcgtgtcgcgccacgatgcgctgcgcacgacg ttcgcgctcgaaggcgagcaaccggttcagcgcgtgcacgcggatgatggcgcggggctg cgcttgcgcatcgacgatctgcgcgggtgcgccgacgccggcgcgcggcgcgcgcggatc ctggccgggcaggcgagcgagccgttcgatctggcgcgcgggccgctggttcgcggcgcg ctcgtgcgcgaggccgacgacgtgcacacgctatgcgtgacgatccatcacatcgtgtcg gacggctggtcgatcgacgtgttctgccgcgaactgagcgagttgtatcgcgcattcgcc ggcgggcggcccgacccgttgccgccgctgccggtgcagtacgccgattacgcggcgtgg cagcaacgcggcatcggcggcgcggcgctgcacgcgcaggccgaatactggcgcgatgcg ctcgcgggtgcgccgacgctgctcgaactgccgacggaccggccgcgtccgccgcagcca gactatgcgggcgcgacggtcgggctcgcgctcgacgcgccgctgacggcgggcttgcgc gcgctcgcgcggcgtcacggcgcgacgctcttcatgaccgtgttcgccgcgtggagcgtg ctgctgtcgcgcctgtcgcggcaaaccgacgtggtgatcggcacgccgagcgcgaaccgc ggccatgcgcagatcgagggcttgatcggctttttcgtcaacacgatcgcgctgcgcgtg gacctcgacggcgcgccgaccgtggccgagctgctcgcgcgcgtgaaggcgcgcacgctc gccgcgcagcagcatcaggacattccgttcgagcatgtggtcgagcgggtacagccggcg cgcagtctctcgcatagcccggtgtttcaggcgatgttcgcgtggcagcacgcgtcgcgc ggcgagatgcggctcgaagggctgcgcgcggagccgctcgacgacgcggcgcgcacgatc gcgaagttcgatctgacgctgtcgctgcgcgagagcggcgatgcgatcgacggcggtctc gaatacgcgagcgcgctgttcgagcgcgcgacgatcgagcgcttcgccggctacctgcgg cgtttgctggaagggatggtcgcggacgacacgcagcgcgtcgatgcattgccgatgctg tcgcgcgacgaacggcgcgatctgatcgagcgccggaacgcgaccgcgcggccgtatccg gcgaacagcggcgtgcatcggctgttcgaggcgcaggcggcgcgcacgcccgatgcgacc gcgatcgtcgacggggcgacgacgctcgactatcgcgcgctcgatgcgcgcgcgaaccgc atcgcacacgcgctcgcgcacgccggcgtgcgcgcgggcgatcgcgtcgcgctgcatctc gagccgtcgatcgggctcgtcgcggcgcagctcgcggtgctcaagctcggcgccgcctac gtgcccgtcgatgtcggcaatccgcccgcgcgcaaggcgttcgtcgcgcaagacagcggc gcgcggctcgtgctcggcgacgcggcgctcgactggccggcggcggccggcgtgccgcag cgcgatctggcggcgctgctcgccgggccgtggccgtcggacgcgcccgctcgcgcgccg cagtgcggcggcgacacaccggcatacgtgatgtacacgtcgggctcgagcgggcagccg aagggcgtgctcgtcacgcatcgcggcatcgcgcggctggcggtgaacagcggttatgcg acgttcgacgcgtcggaccggttcgcgttcgcatcgaacccggcgttcgacgcatcgacg ttcgaagtgtggacggcgcttctcaacggcgcgagcatcggcatcgtgaagcgcgacgat ctgctcgatctcggcgcgctcgccggcaagctgtcgtcgatcggcgtcacctgtctgttc ctcacgacggcgctgttcaaccggtgcgtgtcgttcgatccggcgatgttcgcgcggctg cgctgcgtgatctcgggcggcgagcgcgccgatccggcggtctaccggaaggtgctggaa gcgggcccgccgcgccatctgctgaacgcgtacggcccgaccgagaccaccacgttcgcc gcggtctgggaagccgagccgcgcacgctcgccgcgcaggccgcgccgatcgggcggccg atcggcaatacgtcggtctacgtgctcgacgcgtacggcgcgccggtgcccgtcggcgtg acgggcgagatccacatcggcggcccgggtgtcgcgcaaggctacctgaaccgaccggcg ctttcggccgagcgcttcgtgcgcgatccgttcgtcggcggcgacgcgcggatgtaccgc acgggcgacctcggccgatggcggcccgacggcatgctcgactgcatcggccgcgccgac ttccaggtgaagattcgcggctttcggatcgagctcggcgaaatcgaagcgtgcctgctc gaacacggcgcgctcgcgcaggcggcggtgctcgcgcgcgacgacggcggcgacggcggc aagacgctcgtcgcgtattacgtgccgcgcgcggggcacgaggatggcgcgcccgcgctg cgcgcgcatctggccgcacgcctgcccgaatacatggtgcccgccgcgtacgtgcggctg ccggcgatgccgctcacgcccaacggcaagctcgagcgccgcgcgctgcccgcccccgac gagcgatcgtacgtgcggcgcgactacgcggcgccgcagggcgagatcgagacgacactc gcgcggatctgggcggagctgttcggcatcgagcgcgtcggccggcacgacggcttcttc gaactcggcgggcattcgctgctcgcggtgcggatggtcgcgcgcgtgcacgatgtgctg ggcgtcgaggtgccgctgcgcgcgctgttcgccgatccggtgctgcacgtgttcgcgtcg gcggtcgcgcgcgcgtcgacgcgccaggcgtcgtcgaatctcgtcgcgttccgcagcgcg ggcacggccgcgccgctcttcttcattcattcggggctcggcgagatcggcttcgtcggc gatctgctgcccggcatcgcgccggagattccggtgtacggcttcgcggcggtcggcttc ctcgcgggcgagacgccgcacgcgacgatcgaggagatggccgcgcaatatgtcgacgcg atgcggcgcgtgcagccgcatgggccgtatcggctcgccgggtggtgcgcgggcggcaac atcgcgttcgaaatggcccatcagctgatcgcggccgacgagacggtcgagttcctctgc atgatcgattcgccgacgtccgcgccgatcgaccgctcggtcaccgcgtgcgtgctcgcg cgcattcccgacgacattccggaggcgttgcgcacgcggcttcatgcgctcggcgatgcc ttcgacgtgcgcggcatgctgcacgcgtgccaggcggcgggcatgctgccgatcgatctg ccgaccgggctgatggagcggcacgtcgcggtgcaatacgcgatcaagcatgcgaagctg aactacgtgccgccgcgtttgcccgtcgacgtgattcacttcgtcgcgcaggacgagccg atgtggcgcaacggctgggcgatggacggctggcacgacgtcgcggaccgggtgatctgc ctgcccgcgagcggcgaccacatgacgatggtggcggcgccgcacgcggagcaactgggg cggcgcatcacggaggcgctcgccgtgcacggcgggccgcgcgcggatggcgcggagcgc ggctacgcgccgcgcatcgcgatccagacggccccgcgcgacgcgcgcgcgccgacgctc ttctgcattccgggcgccggcgcgagcgtgacgacgttctcgacgctcgcgcggcatctg ccggcgacgttctccgtggacgggctgcagccgcgcggcctgtgcgggacgatggtgccg tatctcgacgtcgagacggccgcgcgcgcgtacctgagaagcatccggaaagccgcgccg cgcgggccgtaccacctcgtcggccattcgttcggcggctgggtggcctacgagatcgcg tgccggctgcaggagcagggcgagcgcgtcgcgacgctgatgctgctcgacaccgagcgg cccggcgcgaccgacatcgtgcgcgggcgcaagacgcgcgtggacgcgctcgcgaagctc gtcgagctgtacgagatgcatctgggccgcccgctcggtgtgagccgcgacgatctggcc gcgctcgcgcacgacgcgcagatcgagcatctgcgtgcggcgctcgtgcgcgcgaagatc ctgccgccgtccgtgcatccgaacgtgctgcttggcgtcgtgcgggtgctcgagatgaac gtgaacacgccgtatcggcccgcgggtctctacgcggggacgatgcacgtcgtgctgatc gcgaacgcgaaagcggacgcggacctcgacgcgtggcgcgacgagcaggccgagcagtgg cgcggcctcgcggacgacgtgcggatcgtgcgcgcgggcggcaatcacatgacgatgctg cagccgccgcacgcggcgtcgatcgcggcgctgctcgagcgcacggccggcgcgcccgcg cggctcgcgcaggtgcactag

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